Hypothesis

20 Matching Annotations

Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Microglia-derived APOE2 improves remyelination even in the presence of endogenous APOE4

1
1. scibot 23 Jan 2026
  
  in Public
  
  RRID:IMSR_JAX:031820
  
  DOI: 10.1186/s12974-025-03639-5
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:031820
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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12802005/
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Single-Cell Approaches Define the Murine Leptomeninges: Cortical Brain Interface as a Distinct Cellular Neighborhood Composed of Neural and Non-neural Cell Types

1
1. scibot 07 Sep 2025
  
  in Public
  
  RRID:IMSR_JAX:031820
  
  DOI: 10.1523/ENEURO.0046-25.2025
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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RRID:IMSR_JAX:031820

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12376965/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Microglia overexpressing brain-derived neurotrophic factor promote vascular repair and functional recovery in mice after spinal cord injury

1
1. scibot 24 May 2025
  
  in Public
  
  RRID:IMSR_JAX:031820
  
  DOI: 10.4103/NRR.NRR-D-24-00381
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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RRID:IMSR_JAX:031820

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12094574/
elifesciences.org elifesciences.org

Microglia aging in the hippocampus advances through intermediate states that drive activation and cognitive decline

2
1. scibot 22 May 2025
  
  in Public
  
  RRID:IMSR_JAX:031820
  
  DOI: 10.7554/eLife.97671
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
2. scibot 17 May 2025
  
  in Public
  
  Stock 031820
  
  DOI: 10.7554/eLife.97671
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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elifesciences.org/articles/97671
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints

1
1. scibot 07 Nov 2024
  
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  031820
  
  DOI: 10.1038/s41590-023-01627-6
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @AleksanderDrozdz
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC10863749/
Aug 2024
www.sciencedirect.com www.sciencedirect.com

Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes

1
1. scibot 20 Aug 2024
  
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  #031820
  
  DOI: 10.1016/j.celrep.2024.114637
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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scibot

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sciencedirect.com/science/article/pii/S2211124724009872
Apr 2024
www.sciencedirect.com www.sciencedirect.com

CCR2+ monocytes replenish border-associated macrophages in the diseased mouse brain

1
1. scibot 19 Apr 2024
  
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  JAX:031820
  
  DOI: 10.1016/j.celrep.2024.114120
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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scibot

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sciencedirect.com/science/article/pii/S2211124724004480
www.sciencedirect.com www.sciencedirect.com

LXR/CD38 activation drives cholesterol-induced macrophage senescence and neurodegeneration via NAD+ depletion

1
1. scibot 18 Apr 2024
  
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  JAX:031820
  
  DOI: 10.1016/j.celrep.2024.114102
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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RRID:IMSR_JAX:031820

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scibot

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sciencedirect.com/science/article/pii/S2211124724004303
Mar 2024
www.sciencedirect.com www.sciencedirect.com

Neutrophil-inflicted vasculature damage suppresses immune-mediated optic nerve regeneration

1
1. scibot 19 Mar 2024
  
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  The Jackson LaboratoryStock# 031820
  
  DOI: 10.1016/j.celrep.2024.113931
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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RRID:IMSR_JAX:031820

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scibot

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sciencedirect.com/science/article/pii/S2211124724002596
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Fate mapping of Spp1 expression reveals age-dependent plasticity of disease-associated microglia-like cells after brain injury

1
1. scibot 06 Feb 2024
  
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  JAX:031820
  
  DOI: 10.1016/j.immuni.2024.01.008
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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RRID:IMSR_JAX:031820

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scibot

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sciencedirect.com/science/article/pii/S1074761324000323
Jan 2024
www.sciencedirect.com www.sciencedirect.com

A comparative evaluation of the strengths and potential caveats of the microglial inducible CreER mouse models

1
1. scibot 18 Jan 2024
  
  in Public
  
  RRID:IMSR_JAX:031820
  
  DOI: 10.1016/j.celrep.2023.113660
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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RRID:IMSR_JAX:031820

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scibot

URL

sciencedirect.com/science/article/pii/S2211124723016716
Dec 2023
www.sciencedirect.com www.sciencedirect.com

Microglia promote remyelination independent of their role in clearing myelin debris

1
1. scibot 16 Dec 2023
  
  in Public
  
  The Jackson LaboratoryCat# 031820
  
  DOI: 10.1016/j.celrep.2023.113574
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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RRID:IMSR_JAX:031820

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scibot

URL

sciencedirect.com/science/article/pii/S2211124723015863
Aug 2023
www.sciencedirect.com www.sciencedirect.com

A comparative analysis of microglial inducible Cre lines

1
1. scibot 30 Aug 2023
  
  in Public
  
  RRID:IMSR_JAX:031820
  
  DOI: 10.1016/j.celrep.2023.113031
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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RRID:IMSR_JAX:031820

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scibot

URL

sciencedirect.com/science/article/pii/S2211124723010422
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Optical opening of the blood-brain barrier for targeted and ultra-sparse viral infection of cells in mouse cortex

1
1. scibot 12 Jul 2023
  
  in Public
  
  RRID:IMSR_JAX:031820
  
  DOI: 10.1016/j.crmeth.2023.100489
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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RRID:IMSR_JAX:031820

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10326348/
May 2023
52.53.155.43 52.53.155.43

Finding the right tool: a comprehensive evaluation of microglial inducible cre mouse models

1
1. scibot 27 May 2023
  
  in Public
  
  RRID:IMSR_JAX:031820
  
  DOI: 10.1101/2023.04.17.536878
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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RRID:IMSR_JAX:031820

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scibot

URL

52.53.155.43/212e4b73c62c195b3a5740795c4e69d16edaaa96/2023.04.17.536878v1.full-html.html
Feb 2023
www.sciencedirect.com www.sciencedirect.com

The mechanosensitive ion channel Piezo1 modulates the migration and immune response of microglia

1
1. scibot 09 Feb 2023
  
  in Public
  
  JAX:031
  
  DOI: 10.1016/j.isci.2023.105993
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @sofiakhan13
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820 RRIDCUR:Unresolved
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RRID:IMSR_JAX:031820

RRIDCUR:Unresolved

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scibot

URL

sciencedirect.com/science/article/pii/S2589004223000706
dm5migu4zj3pb.cloudfront.net dm5migu4zj3pb.cloudfront.net

161507.1-20230126111242-covered-e0fd13ba177f913fd3156f593ead4cfd.pdf

1
1. scibot 07 Feb 2023
  
  in Public
  
  031820
  
  DOI: 10.1172/JCI161507
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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RRID:IMSR_JAX:031820

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scibot

URL

dm5migu4zj3pb.cloudfront.net/manuscripts/161000/161507/cache/161507.1-20230126111242-covered-e0fd13ba177f913fd3156f593ead4cfd.pdf
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Brain region- and sex-specific transcriptional profiles of microglia

1
1. scibot 09 Sep 2022
  
  in Public
  
  RRID:IMSR_JAX:031820
  
  DOI: 10.3389/fpsyt.2022.945548
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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RRID:IMSR_JAX:031820

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9448907/
Jul 2021
www.sciencedirect.com www.sciencedirect.com

GABA-receptive microglia selectively sculpt developing inhibitory circuits

1
1. scibot 07 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:031820
  
  DOI: 10.1016/j.cell.2021.06.018
  
  Resource: (IMSR Cat# JAX_031820,RRID:IMSR_JAX:031820)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:031820
  
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  RRID:IMSR_JAX:031820
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RRID:IMSR_JAX:031820

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scibot

URL

sciencedirect.com/science/article/pii/S0092867421007534