34 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer’s Disease
    1
    1. scibot 14 Nov 2024
      100012

      DOI: 10.1021/acs.jmedchem.0c00278

      Resource: (IMSR Cat# JAX_100012,RRID:IMSR_JAX:100012)

      Curator: @AleksanderDrozdz

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    pmc.ncbi.nlm.nih.gov/articles/PMC8025741/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Super-Resolution Ultrasound Reveals Cerebrovascular Impairment in a Mouse Model of Alzheimer's Disease
    1
    1. scibot 07 Nov 2024
      100012

      DOI: 10.1523/JNEUROSCI.1251-23.2024

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      Curator: @AleksanderDrozdz

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    pmc.ncbi.nlm.nih.gov/articles/PMC10904092/
  4. Sep 2024
  5. academic.oup.com academic.oup.com
    Reduced levels of MRE11 cause disease phenotypes distinct from ataxia telangiectasia-like disorder
    1
    1. scibot 26 Sep 2024
      Stock number 100012

      DOI: 10.1093/hmg/ddae101

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      Curator: @vtello

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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddae101/7695534
  6. Aug 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduction of human Alzheimer’s disease risk and reversal of mouse model cognitive deficit with nucleoside analog use
    1
    1. scibot 02 Aug 2024
      100012

      DOI: 10.1101/2023.03.17.23287375

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      Curator: @bandrow

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    ncbi.nlm.nih.gov/pmc/articles/PMC10055589/
  8. www.mdpi.com www.mdpi.com
    An Intercellular Flow of Glutathione Regulated by Interleukin 6 Links Astrocytes and the Liver in the Pathophysiology of Amyotrophic Lateral Sclerosis
    1
    1. scibot 02 Aug 2024
      100012

      DOI: 10.3390/antiox10122007

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      Curator: @Naa003

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      RRID:IMSR_JAX:100012 RRIDCUR:Missing
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    mdpi.com/2076-3921/10/12/2007/htm
  9. Jun 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease
    1
    1. scibot 27 Jun 2024
      Jackson LabsStock# 100012

      DOI: 10.7554/eLife.89889

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      Curator: @evieth

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      DOI:10.7554/eLife.89889 RRID:IMSR_JAX:100012
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    ncbi.nlm.nih.gov/pmc/articles/PMC11192536/
  11. May 2024
  12. www.sciencedirect.com www.sciencedirect.com
    The first two blastomeres contribute unequally to the human embryo
    1
    1. scibot 14 May 2024
      RRID:IMSR_JAX:100012

      DOI: 10.1016/j.cell.2024.04.029

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      Curator: @scibot

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    sciencedirect.com/science/article/pii/S0092867424004550
  13. Jan 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Bezafibrate confers neuroprotection in the 5xFAD mouse model of Alzheimer's disease
    1
    1. scibot 02 Jan 2024
      100012

      DOI: 10.1016/j.bbadis.2023.166841

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    sciencedirect.com/science/article/pii/S0925443923002077
  15. Jul 2023
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    E protein binding at the Tcra enhancer promotes Tcra repertoire diversity
    1
    1. scibot 22 Jul 2023
      JAX:100012

      DOI: 10.3389/fimmu.2023.1188738

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      Curator: @scibot

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    ncbi.nlm.nih.gov/pmc/articles/PMC10358851/
  17. Apr 2023
  18. 52.53.155.43 52.53.155.43
    MeCP2 Represses the Activity of Topoisomerase IIβ in Long Neuronal Genes
    1
    1. scibot 12 Apr 2023
      JAX:100012

      DOI: 10.1101/2023.02.24.529960

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      Curator: @scibot

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    52.53.155.43/f9112145f5ddb849897c97bd39c4325cb2ff350e/2023.02.24.529960v1.full-html.html
  19. Mar 2023
  20. www.frontiersin.org www.frontiersin.org
    The Therapeutic and Diagnostic Potential of Amyloid β Oligomers Selective Antibodies to Treat Alzheimer’s Disease
    1
    1. scibot 22 Mar 2023
      JAX:100012

      DOI: 10.3389/fnins.2021.768646

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    frontiersin.org/articles/10.3389/fnins.2021.768646/full
  21. Apr 2022
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blood-brain barrier permeability is regulated by lipid transport-dependent suppression of caveolae-mediated transcytosis
    1
    1. scibot 21 Apr 2022
      JAX:100012

      DOI: 10.1016/j.neuron.2017.03.043

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      Curator: @scibot

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    ncbi.nlm.nih.gov/pmc/articles/PMC5474951/
  23. Jan 2022
  24. www.sciencedirect.com www.sciencedirect.com
    Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation
    1
    1. scibot 16 Jan 2022
      JAX:100012

      DOI: 10.1016/j.celrep.2021.110231

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    sciencedirect.com/science/article/pii/S221112472101740X
  25. Dec 2021
  26. 52.53.155.43 52.53.155.43
    Anti-Neuroinflammatory Effects of a Semi-Synthetic Isoorientin-Based Glycogen Synthase Kinase-3β Inhibitor in Lipopolysaccharide-Activated Microglial Cells
    2
    1. scibot 21 Dec 2021
      RRID:IMSR_JAX:100012

      DOI: 10.1021/acschemneuro.1c00537

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      Curator: @scibot

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      RRID:IMSR_JAX:100012
    2. scibot 21 Dec 2021
      RRID:IMSR_JAX:100012

      DOI: 10.1021/acschemneuro.1c00537

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    52.53.155.43/ee11fa5e17c1cbf98df95798a21c393bc1f1bd99/acschemneuro.1c00537-html.html
  27. Jul 2021
  28. www.sciencedirect.com www.sciencedirect.com
    MLL1 Inhibition and Vitamin D Signaling Cooperate to Facilitate the Expanded Pluripotency State
    1
    1. scibot 31 Jul 2021
      Jackson LaboratoryCat# 100012

      DOI: 10.1016/j.celrep.2019.10.074

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      Curator: @bandrow

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      RRID:IMSR_JAX:100012 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2211124719313968
  29. www.sciencedirect.com www.sciencedirect.com
    The Anti-amyloid Compound DO1 Decreases Plaque Pathology and Neuroinflammation-Related Expression Changes in 5xFAD Transgenic Mice
    1
    1. scibot 31 Jul 2021
      RRID:IMSR_JAX:100012

      DOI: 10.1016/j.chembiol.2018.10.013

      Resource: (IMSR Cat# JAX_100012,RRID:IMSR_JAX:100012)

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    sciencedirect.com/science/article/pii/S2451945618303465
  30. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protection Against β‐Amyloid Neurotoxicity by a Non‐Toxic Endogenous N‐terminal β‐Amyloid Fragment and its Active Hexapeptide Core Sequence
    2
    1. scibot 29 Jul 2021
      RRID:IMSR_JAX:100012

      DOI: 10.1111/jnc.14257

      Resource: (IMSR Cat# JAX_100012,RRID:IMSR_JAX:100012)

      Curator: @evieth

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      RRIDCUR:Duplicate RRID:IMSR_JAX:100012 RRIDCUR:Validated
    2. scibot 29 Jul 2021
      RRID:IMSR_JAX:100012

      DOI: 10.1111/jnc.14257

      Resource: (IMSR Cat# JAX_100012,RRID:IMSR_JAX:100012)

      Curator: @evieth

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      RRID:IMSR_JAX:100012 RRIDCUR:Validated
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14257/full
  31. www.jneurosci.org www.jneurosci.org
    α2δ-4 is required for the molecular and structural organization of rod and cone photoreceptor synapses
    1
    1. scibot 28 Jul 2021
      RRID:IMSR_JAX:100012

      DOI: 10.1523/JNEUROSCI.3818-16.2018

      Resource: (IMSR Cat# JAX_100012,RRID:IMSR_JAX:100012)

      Curator: @evieth

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      RRIDCUR:Unrecognized RRID:IMSR_JAX:100012
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    jneurosci.org/content/38/27/6145
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 27 Jul 2021
      RRID:IMSR_JAX:100012

      DOI: 10.1016/j.neuron.2018.03.010

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      Curator: @scibot

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      RRID:IMSR_JAX:100012
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    ncbi.nlm.nih.gov/pmc/articles/PMC5919779/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MouseBytes, an open-access high-throughput pipeline and database for rodent touchscreen-based cognitive assessment
    1
    1. scibot 27 Jul 2021
      RRID:MGI:100012

      DOI: 10.7554/eLife.49630

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      Curator: @evieth

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      RRIDCUR:Unresolved RRIDCUR:SyntaxError RRID:IMSR_JAX:100012
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    ncbi.nlm.nih.gov/pmc/articles/PMC6934379/
  34. www.sciencedirect.com www.sciencedirect.com
    Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents
    1
    1. scibot 27 Jul 2021
      RRID:_IMSR_JAX:100012

      DOI: 10.1016/j.chembiol.2019.10.005

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      Curator: @ethanbadger

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      RRIDCUR:Unresolved RRIDCUR:SyntaxError RRID:IMSR_JAX:100012
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    sciencedirect.com/science/article/pii/S2451945619303502
  35. May 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation
    1
    1. scibot 04 May 2021
      100012

      DOI: 10.1016/j.devcel.2020.04.018

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      Curator: @Naa003

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      RRID:IMSR_JAX:100012 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1534580720303506
  37. Apr 2021
  38. www.sciencedirect.com www.sciencedirect.com
    p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)
    1
    1. scibot 24 Apr 2021
      JAX:100012

      DOI: 10.1016/j.cell.2020.12.025

      Resource: (IMSR Cat# JAX_100012,RRID:IMSR_JAX:100012)

      Curator: @scibot

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      RRID:IMSR_JAX:100012
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    sciencedirect.com/science/article/pii/S0092867420317475
  39. Mar 2021
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic disruption of WASHC4 drives endo-lysosomal dysfunction and cognitive-movement impairments in mice and humans
    1
    1. scibot 28 Mar 2021
      RRID:IMSR_JAX:100012

      DOI: 10.7554/eLife.61590

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      Curator: @evieth

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      RRID:IMSR_JAX:100012 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC7984842/
  41. Jan 2021
  42. www.sciencedirect.com www.sciencedirect.com
    MCT1 Deletion in Oligodendrocyte Lineage Cells Causes Late-Onset Hypomyelination and Axonal Degeneration
    1
    1. scibot 22 Jan 2021
      Cat#100012

      DOI: 10.1016/j.celrep.2020.108610

      Resource: (IMSR Cat# JAX_100012,RRID:IMSR_JAX:100012)

      Curator: @Naa003

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      RRID:IMSR_JAX:100012 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2211124720315990
  43. Oct 2020
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A dual role for Cav1.4 Ca2+ channels in the molecular and structural organization of the rod photoreceptor synapse
    1
    1. scibot 27 Oct 2020
      RRID:IMSR_JAX:100012

      DOI: 10.7554/eLife.62184

      Resource: (IMSR Cat# JAX_100012,RRID:IMSR_JAX:100012)

      Curator: @evieth

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      RRID:IMSR_JAX:100012
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    ncbi.nlm.nih.gov/pmc/articles/PMC7561352/
  45. Jan 2020
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a resilient mouse facial motoneuron population following target disconnection by injury or disease
    1
    1. scibot 13 Jan 2020
      JAX:100012

      DOI: 10.3233/RNN-170809

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      RRID:IMSR_JAX:100012 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6373730/
  47. www.sciencedirect.com www.sciencedirect.com
    Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:100012

      DOI: 10.1016/j.chembiol.2019.10.005

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      Curator: @ethanbadger

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      RRID:IMSR_JAX:100012 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2451945619303502
  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A novel crosslinking protocol stabilizes amyloid β oligomers capable of inducing Alzheimer's‐associated pathologies
    1
    1. scibot 12 Jan 2020
      RRID:IMSR_JAX:100012

      DOI: 10.1111/jnc.14647

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      Curator: @ethanbadger

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      RRID:IMSR_JAX:100012 RRIDCUR:Validated
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14647
  49. Nov 2018
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency
    1
    1. scibot 05 Nov 2018
      JAX:100012

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      RRID:IMSR_JAX:100012

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      RRID:IMSR_JAX:100012
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    ncbi.nlm.nih.gov/pmc/articles/PMC6091870/
  51. www.sciencedirect.com www.sciencedirect.com
    Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency
    1
    1. scibot 05 Nov 2018
      JAX:100012

      Curator: @evieth

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      RRID:IMSR_JAX:100012

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      RRID:IMSR_JAX:100012 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124718308970
  52. www.sciencedirect.com www.sciencedirect.com
    Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:100012

      Curator: @anp055

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      RRID:IMSR_JAX:100012

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      RRID:IMSR_JAX:100012 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627318301879