29 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IOA-244, a novel p110δ PI3K inhibitor, blocks breast tumour progression on either mono- or combined-therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13184035/
  3. www.sciencedirect.com www.sciencedirect.com
    Transcriptome-guided development of a fibrosis-reversal compound reduces skin scarring and allows regeneration via mitochondrial uncoupling
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    sciencedirect.com/science/article/pii/S2666379126002387
  4. May 2026
  5. aacrjournals.org aacrjournals.org
    PCBP2 Mediates Olaparib Resistance in Breast Cancer by Inhibiting m6A Methylation to Stabilize PARP1 mRNA
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    aacrjournals.org/cancerres/article/85/20/3949/766094/PCBP2-Mediates-Olaparib-Resistance-in-Breast
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pertuzumab Enhances the Antitumor Activity of T-DXd in HER2-Positive Gastric Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13136884/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    JIN-A02, a Mutant-Selective Fourth-Generation EGFR inhibitor, Overcomes C797S-Mediated Resistance and Demonstrates Intracranial Activity in NSCLC
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133602/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical Characterization and Clinical Activity of RNK08954, a Highly Selective and Orally Bioavailable KRAS G12D Inhibitor
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133609/
  9. Apr 2026
  10. aacrjournals.org aacrjournals.org
    ACYP2 induces temozolomide resistance in glioblastoma by promoting PARP1-mediated DNA damage repair
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    aacrjournals.org/mcr/article/24/1/7/771152/ACYP2-Induces-Temozolomide-Resistance-in
  11. 54.241.53.176 54.241.53.176
    cd-25-1346-html.html
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    54.241.53.176/86f1cde136cae9cb2b05401d7da6d7a0a1acbc52/cd-25-1346-html.html
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PTEN Loss Promotes PI3Kβ Phosphorylation and EPHA2/SRC/p-PI3KβY962 Complex Assembly to Drive Tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13056290/
  13. aacrjournals.org aacrjournals.org
    Development of multivalent FAP-targeted Small Molecule-Drug Conjugates with tailored MMAE release kinetics
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    aacrjournals.org/mct/article/24/10/1487/765486/Development-of-Multivalent-FAP-Targeted-Small
  14. Mar 2026
  15. www.sciencedirect.com www.sciencedirect.com
    YTHDF3 facilitates DNA damage response by recognizing METTL3-mediated m6A modification to promote chemotherapy resistance in glioblastoma
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    sciencedirect.com/science/article/pii/S0304383526002089
  16. Feb 2026
  17. www.nature.com www.nature.com
    Epigenetic regulation of NDGA and its synergistic inhibition with EZH2 inhibitors in prostate cancer via NRP1
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    nature.com/articles/s41401-026-01754-4
  18. Jan 2026
  19. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Tumor Extracellular Vesicles lncOSLMT Drives Lung Inflammatory Premetastatic Niche Formation in Osteosarcoma via m6A-Dependent hnRNPA2B1/COX-2 Axis
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202519490
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FNDC4 Drives Metastasis and Immune Evasion in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12809120/
  21. www.sciencedirect.com www.sciencedirect.com
    Deubiquitinase USP45 stabilizes RTCB and DDX1, promoting tumorigenesis and chemoresistance
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    sciencedirect.com/science/article/pii/S0141813025105278
  22. www.nature.com www.nature.com
    PDZRN4 suppresses lung adenocarcinoma progression via inhibiting ubiquitin-mediated HIF-1A degradation
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    nature.com/articles/s41388-025-03670-z
  23. Dec 2025
  24. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Lung adenocarcinoma surfaceome remodeling with EGFR inhibitors uncovers placental alkaline phosphatase as a target for combination therapy
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    sciencedirect.com:5037/science/article/pii/S2666379125005865
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Bi-steric, mTORC1-Selective Inhibitor, RMC-5552, in Advanced Solid Tumors: A Phase 1 Trial
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666311/
  26. Nov 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP10-mediated deubiquitination and activation of KRAS mutants promotes colorectal cancer via a novel USP10/KRAS positive feedback circuit
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    pmc.ncbi.nlm.nih.gov/articles/PMC12827889/
  28. Oct 2025
  29. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Erucic Acid, Derived by Lactobacillus Crispatus, Induces Ferroptosis in Cervical Cancer Organoids Through the PPAR-δ Signaling Pathway
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202512599
  30. Jul 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    68Ga-NK224 PET/CT for Noninvasive Evaluation of PD-L1 Expression and Intertumor Heterogeneity: A Translational Exploratory Study
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260512/
  32. Jun 2025
  33. www.science.org www.science.org
    Adoptive cell therapy with macrophage-drug conjugates facilitates cytotoxic drug transfer and immune activation in glioblastoma models
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    science.org/doi/10.1126/scitranslmed.adr4058
  34. May 2025
  35. www.nature.com www.nature.com
    NUDT21 lactylation reprograms alternative polyadenylation to promote cuproptosis resistance
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    nature.com/articles/s41421-025-00804-1
  36. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/1f223659e065ae2334abaabf911eb2b757fce79a/PDF-html.html
  37. May 2024
  38. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Discovery of a novel potent EGFR inhibitor against EGFR activating mutations and on-target resistance in NSCLC
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    pubmed.ncbi.nlm.nih.gov/38330145/
  39. Mar 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10905675/
  41. Feb 2024
  42. 52.53.155.43 52.53.155.43
    cd-23-0954-html.html
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    52.53.155.43/aaf525c30ae01b53e260240fad732783dfb4bbac/cd-23-0954-html.html