98 Matching Annotations
  1. Aug 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Positive Allosteric Modulation of M1 mAChRs with VU0486846 Reverses Cognitive Deficits in Male APPswe/PSEN1ΔE9 Alzheimer’s Mice
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    sciencedirect.com/science/article/pii/S0028390825003624
  3. www.sciencedirect.com www.sciencedirect.com
    Andrographolide modulates glucose metabolism in visceral adipose tissue in an Alzheimer's disease obese mouse model
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    sciencedirect.com/science/article/pii/S0021925825024585
  4. www.sciencedirect.com www.sciencedirect.com
    Reconstructed cell-type-specific rhythms in human brain link Alzheimer’s pathology, circadian stress, and ribosomal disruption
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    sciencedirect.com/science/article/pii/S0896627325005173
  5. www.science.org www.science.org
    A wearable spatiotemporal controllable ultrasonic device with amyloid-β disaggregation for continuous Alzheimer’s disease therapy
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    science.org/doi/10.1126/sciadv.adw1732
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A wearable spatiotemporal controllable ultrasonic device with amyloid-β disaggregation for continuous Alzheimer’s disease therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12309685/
  7. Jul 2025
  8. www.researchsquare.com www.researchsquare.com
    Cannabidiol modulates brain copper homeostasis in wild-type-like but not Alzheimer’s disease transgenic female mice: Implications for neuroprotective therapy
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    researchsquare.com/article/rs-6727849/v1
  9. link.springer.com link.springer.com
    Impaired hippocampal circuit function underlying memory encoding and consolidation precede robust Aβ deposition in a mouse model of alzheimer’s disease
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    link.springer.com/article/10.1038/s41598-025-05653-2
  10. Jun 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer’s Disease Mouse Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12154612/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lecanemab Binds to Transgenic Mouse Model‐Derived Amyloid‐β Fibril Structures Resembling Alzheimer's Disease Type I, Type II and Arctic Folds
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    pmc.ncbi.nlm.nih.gov/articles/PMC12152531/
  13. Mar 2025
  14. onlinelibrary.wiley.com onlinelibrary.wiley.com
    CPNE7 Regulates Amyloidogenesis Through CAP1-Dependent ADAM10 Translation
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70026
  15. Feb 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Muscle Cathepsin B treatment improves behavioral and neurogenic deficits in a mouse model of Alzheimer’s Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11785056/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Regulation of cell distancing in peri-plaque glial nets by Plexin-B1 affects glial activation and amyloid compaction in Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11346591/
  18. Jan 2025
  19. molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com
    SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease
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    molecularneurodegeneration.biomedcentral.com/counter/pdf/10.1186/s13024-024-00788-8.pdf
  20. link.springer.com link.springer.com
    SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease
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    link.springer.com/article/10.1186/s13024-024-00788-8
  21. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225000112-main-html.html
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    52.53.155.43/f3927b613620da7ae9927001d3d9d5a924748cb9/1-s2.0-S2589004225000112-main-html.html
  22. Nov 2024
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vitamin C deficiency increases basal exploratory activity but decreases scopolamine-induced activity in APP/PSEN1 transgenic mice
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC2828687/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PET neuroimaging studies of [18F]CABS13 in a double transgenic mouse model of Alzheimer’s disease and non-human primates
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    pmc.ncbi.nlm.nih.gov/articles/PMC4879824/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Wnt-induced activation of glucose metabolism mediates the in vivo neuroprotective roles of Wnt signaling in Alzheimer disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC7680578/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuroinflammation increases oxygen extraction in a mouse model of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11005245/
  27. Sep 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early hippocampal hyperexcitability and synaptic reorganization in mouse models of amyloidosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11388185/
  29. Aug 2024
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology, cognition, and behavior in APP/PS1 mice
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11317949/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chimeric antigen receptor macrophages target and resorb amyloid plaques
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    pmc.ncbi.nlm.nih.gov/articles/PMC11063938/
  32. www.frontiersin.org www.frontiersin.org
    LRRC25 expression during physiological aging and in mouse models of Alzheimer’s disease and iPSC-derived neurons
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    frontiersin.org/articles/10.3389/fnmol.2024.1365752
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sex-dependent effects of acute stress on amyloid-β in male and female mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC10232275/
  34. www.frontiersin.org www.frontiersin.org
    Acute stressors do not impair short-term memory or attention in an aged mouse model of amyloidosis
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    frontiersin.org/articles/10.3389/fnbeh.2023.1151833
  35. www.frontiersin.org www.frontiersin.org
    Region-specific heterogeneity in neuronal nuclear morphology in young, aged and in Alzheimer’s disease mouse brains
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    frontiersin.org/articles/10.3389/fcell.2023.1032504
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC7941983/
  37. Jul 2024
  38. molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com
    Astrocytic autophagy plasticity modulates Aβ clearance and cognitive function in Alzheimer’s disease
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    molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-024-00740-w
  39. May 2024
  40. www.frontiersin.org www.frontiersin.org
    Extracellular vesicles mediate inflammasome signaling in the brain and heart of Alzheimer’s disease mice
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    frontiersin.org/articles/10.3389/fnmol.2024.1369781
  41. Apr 2024
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Magnesium-L-threonate treats Alzheimer’s disease by modulating the microbiota-gut-brain axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11034594/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    zpae022-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC11025629/
  44. www.sciencedirect.com www.sciencedirect.com
    Exercise-enhanced IGF1R sumoylation-induced nuclear translocation decreases neuroinflammation in alzheimer's mice
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    sciencedirect.com/science/article/pii/S2090123224001279
  45. www.sciencedirect.com www.sciencedirect.com
    The association of GNB5 with Alzheimer disease revealed by genomic analysis restricted to variants impacting gene function
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    sciencedirect.com/science/article/pii/S0002929724000053
  46. Jan 2024
  47. molecularbrain.biomedcentral.com molecularbrain.biomedcentral.com
    Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state
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    molecularbrain.biomedcentral.com/articles/10.1186/s13041-024-01076-8
  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's disease
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    onlinelibrary.wiley.com/doi/full/10.1111/acel.13895
  49. www.mdpi.com www.mdpi.com
    Evaluation of Novel B1R/B2R Agonists Containing TRIOZAN™ Nanoparticles for Targeted Brain Delivery of Antibodies in a Mouse Model of Alzheimer Disease
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    mdpi.com/1420-3049/28/13/5206
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sleep-Deep-Net learns sleep wake scoring from the end-user and completes each record in their style
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    pmc.ncbi.nlm.nih.gov/articles/PMC10769368/
  51. cmjournal.biomedcentral.com cmjournal.biomedcentral.com
    Kai-Xin-San protects against mitochondrial dysfunction in Alzheimer’s disease through SIRT3/NLRP3 pathway
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    cmjournal.biomedcentral.com/articles/10.1186/s13020-023-00722-y
  52. link.springer.com link.springer.com
    Natural and Pathological Aging Distinctively Impacts the Pheromone Detection System and Social Behavior
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    link.springer.com/article/10.1007/s12035-023-03362-3
  53. www.biorxiv.org www.biorxiv.org
    Neuroinflammation increases oxygen extraction in a mouse model of Alzheimer’s disease
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    biorxiv.org/content/10.1101/2023.10.16.562353v1
  54. www.mdpi.com www.mdpi.com
    CRMP2 Participates in Regulating Mitochondrial Morphology and Motility in Alzheimer’s Disease
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    mdpi.com/2073-4409/12/9/1287
  55. www.mdpi.com www.mdpi.com
    Multi-Targeting Intranasal Nanoformulation as a Therapeutic for Alzheimer’s Disease
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    mdpi.com/2218-273X/13/2/232
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deletion of Small GTPase H-Ras Rescues Memory Deficits and Reduces Amyloid Plaque-Associated Dendritic Spine Loss in Transgenic Alzheimer’s Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC10771223/
  57. www.nature.com www.nature.com
    Cryo-EM of Aβ fibrils from mouse models find tg-APPArcSwe fibrils resemble those found in patients with sporadic Alzheimer’s disease
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    nature.com/articles/s41593-023-01484-4
  58. www.biorxiv.org www.biorxiv.org
    Cuprizone drives divergent neuropathological changes in different mouse models of Alzheimer’s disease
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    biorxiv.org/content/10.1101/2023.07.24.547147v1
  59. journals.plos.org journals.plos.org
    Two mouse models of Alzheimer’s disease accumulate amyloid at different rates and have distinct Aβ oligomer profiles unaltered by ablation of cellular prion protein
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    journals.plos.org/plosone/article
  60. Sep 2023
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ligustilide-loaded liposome ameliorates mitochondrial impairments and improves cognitive function via the PKA/AKAP1 signaling pathway in a mouse model of Alzheimer's disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC10916432/
  62. Aug 2023
  63. www.sciencedirect.com www.sciencedirect.com
    MALDI mass spectrometry imaging discloses the decline of sulfoglycosphingolipid and glycerophosphoinositol species in the brain regions related to cognition in a mouse model of Alzheimer's disease
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    sciencedirect.com/science/article/pii/S0039914023007737
  64. May 2023
  65. www.mdpi.com www.mdpi.com
    DEAD-Box Helicase 17 Promotes Amyloidogenesis by Regulating BACE1 Translation
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    mdpi.com/2076-3425/13/5/745
  66. www.mdpi.com www.mdpi.com
    The Memory Benefit to Aged APP/PS1 Mice from Long-Term Intranasal Treatment of Low-Dose THC
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    mdpi.com/1422-0067/23/8/4253/htm
  67. Apr 2023
  68. www.biorxiv.org www.biorxiv.org
    Cryo-EM Structures of Amyloid-β Fibrils from Alzheimer’s Disease Mouse Models
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    biorxiv.org/content/10.1101/2023.03.30.534981v1
  69. Mar 2023
  70. www.biorxiv.org www.biorxiv.org
    Natural and pathological aging distinctively impact the vomeronasal detection system and social behavior
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    biorxiv.org/content/10.1101/2022.08.31.505522v4
  71. www.frontiersin.org www.frontiersin.org
    Trans ε-Viniferin Decreases Amyloid Deposits With Greater Efficiency Than Resveratrol in an Alzheimer’s Mouse Model
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    frontiersin.org/articles/10.3389/fnins.2021.803927/full
  72. www.science.org www.science.org
    Molecular basis of astrocyte diversity and morphology across the CNS in health and disease
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    science.org/doi/10.1126/science.adc9020
  73. www.mdpi.com www.mdpi.com
    Ginsenoside F1 Protects the Brain against Amyloid Beta-Induced Toxicity by Regulating IDE and NEP
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    mdpi.com/2075-1729/12/1/58
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chronic effects of blast injury on the microvasculature in a transgenic mouse model of Alzheimer’s disease related Aβ amyloidosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC8751260/
  75. www.biorxiv.org www.biorxiv.org
    Impact of cellular prion protein expression on disease progression and pathology in two mouse models of Alzheimer’s disease
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    biorxiv.org/content/10.1101/2022.09.25.508690v1
  76. journals.lww.com journals.lww.com
    Inhibiting 5-hydroxytryptamine receptor 3 alleviates... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2023/09000/Inhibiting_5_hydroxytryptamine_receptor_3.30.aspx
  77. Feb 2023
  78. Local file Local file
    Type of the Paper (Article
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  79. Jan 2023
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microglial Expression of the Wnt Signaling Modulator DKK2 Differs between Human Alzheimer’s Disease Brains and Mouse Neurodegeneration Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC9836029/
  81. journals.lww.com journals.lww.com
    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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    journals.lww.com/nrronline/fulltext/2026/04000/the_cullin3_ring_e3_ubiquitin_ligase_complex_and.44.aspx
  82. Dec 2022
  83. journals.lww.com journals.lww.com
    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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    journals.lww.com/nrronline/fulltext/2026/04000/the_cullin3_ring_e3_ubiquitin_ligase_complex_and.44.aspx
  84. Oct 2022
  85. www.nature.com www.nature.com
    A distinct astrocyte subtype in the aging mouse brain characterized by impaired protein homeostasis
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    nature.com/articles/s43587-022-00257-1
  86. Jul 2022
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sex-Related Microglial Perturbation Is Related to Mitochondrial Changes in a Model of Alzheimer’s Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC9297004/
  88. Jun 2022
  89. www.sciencedirect.com www.sciencedirect.com
    Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S1550413122001930
  90. Apr 2022
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Age and Alzheimer’s Disease-Related Oligodendrocyte Changes in Hippocampal Subregions
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    ncbi.nlm.nih.gov/pmc/articles/PMC9023310/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Longitudinal Assessment of Working Memory Performance in the APPswe/PSEN1dE9 Mouse Model of Alzheimer’s Disease Using an Automated Figure-8-Maze
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    ncbi.nlm.nih.gov/pmc/articles/PMC8155296/
  93. www.nature.com www.nature.com
    Inhibition of the CEBPβ-NFκB interaction by nanocarrier-packaged Carnosic acid ameliorates glia-mediated neuroinflammation and improves cognitive function in an Alzheimer’s disease model
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    nature.com/articles/s41419-022-04765-1
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reactive astrocytes as treatment targets in Alzheimer's disease—Systematic review of studies using the APPswePS1dE9 mouse model
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    ncbi.nlm.nih.gov/pmc/articles/PMC8247905/
  95. Feb 2022
  96. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A M1 muscarinic acetylcholine receptor positive allosteric modulator improves pathology and cognitive deficits in female APPswe/PSEN1ΔE9 mice
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15750
  97. Nov 2021
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of Microbiota Sensing – Free Fatty Acid Receptor 2 Signaling Ameliorates Amyloid-β Induced Neurotoxicity by Modulating Proteolysis-Senescence Axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8544178/
  99. Jul 2021
  100. molecularbrain.biomedcentral.com molecularbrain.biomedcentral.com
    Minor ginsenoside F1 improves memory in APP/PS1 mice
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    molecularbrain.biomedcentral.com/articles/10.1186/s13041-019-0495-7
  101. www.spiedigitallibrary.org www.spiedigitallibrary.org
    Revealing brain pathologies with multimodal visible light optical coherence microscopy and fluorescence imaging
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    spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-24/issue-06/066010/Revealing-brain-pathologies-with-multimodal-visible-light-optical-coherence-microscopy/10.1117/1.JBO.24.6.066010.full
  102. Jun 2021
  103. www.sciencedirect.com www.sciencedirect.com
    Hippocampal sub-networks exhibit distinct spatial representation deficits in Alzheimer’s disease model mice
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    sciencedirect.com/science/article/pii/S0960982221007375
  104. www.nature.com www.nature.com
    Microglial metabolism is a pivotal factor in sexual dimorphism in Alzheimer’s disease
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    nature.com/articles/s42003-021-02259-y
  105. May 2021
  106. www.nature.com www.nature.com
    Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer’s disease
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    nature.com/articles/s41398-021-01349-z
  107. Mar 2021
  108. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer’s disease
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15260
  109. Jan 2021
  110. www.sciencedirect.com www.sciencedirect.com
    Development of a PET radioligand selective for cerebral amyloid angiopathy
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    sciencedirect.com/science/article/pii/S0969805120300305
  111. academic.oup.com academic.oup.com
    Gene therapy for Alzheimer’s disease targeting CD33 reduces amyloid beta accumulation and neuroinflammation
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    academic.oup.com/hmg/article/29/17/2920/5892986
  112. www.sciencedirect.com www.sciencedirect.com
    Cell-Type- and Brain-Region-Resolved Mouse Brain Lipidome
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    sciencedirect.com/science/article/pii/S2211124720311219
  113. Dec 2020
  114. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Emodin inhibits Aβ42 aggregation and improves cognitive deficits in Alzheimer's disease transgenic mice
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15156
  115. Sep 2020
  116. onlinelibrary.wiley.com onlinelibrary.wiley.com
    High‐frequency transcranial magnetic stimulation protects APP/PS1 mice against Alzheimer’s disease progress by reducing APOE and enhancing autophagy
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  121. Jan 2020
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    Vasomotion as a Driving Force for Paravascular Clearance in the Awake Mouse Brain
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  123. www.frontiersin.org www.frontiersin.org
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  125. Nov 2018
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  129. www.sciencedirect.com www.sciencedirect.com
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    The conformational epitope for a new Aβ42 protofibril‐selective antibody partially overlaps with the peptide N‐terminal region
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