126 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Alzheimer’s Disease and circadian disruption sex-specifically contribute to a loss of bone maintenance in APP/PS1 model mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC13174557/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effects of Wheat Malt Extract on Molecular and Behavioral Markers in Aged APP/PS1 and Wild-Type Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC13256562/
  4. Jun 2026
  5. pubs.acs.org pubs.acs.org
    Cu(ATSM) Restores Blood–Brain Barrier Abundance of P-Glycoprotein and Improves Cognitive Function in the APP/PS1 Mouse Model of Alzheimer’s Disease
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    pubs.acs.org/doi/10.1021/acschemneuro.6c00252
  6. www.biorxiv.org www.biorxiv.org
    Early Loss of Deep Restorative Sleep and Auditory Stimulus Evoked 40-Hz activity of Hippocampal Parvalbumin Neurons in the APP/PS1 Mouse Model of Alzheimer’s Disease
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    biorxiv.org/content/10.64898/2026.05.26.725476v1
  7. May 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Behavioral and brain-wide neural signatures of sundowning in Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC13131861/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fructose Intake Is Associated with Brain Metabolic Reprogramming and Exacerbation of Alzheimer-like Alterations in APP/PS1 Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC13164289/
  10. Apr 2026
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Endothelial NAD+ depletion drives vascular senescence and neuroinflammation via mtDNA‐cGAS/STING‐CD38 signaling in Alzheimer's disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC13109647/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sex-dependent rescue of memory and synaptic deficits in AD model mice by increasing PSD-95 palmitoylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13031330/
  13. Mar 2026
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Decreased Length of Locus Coeruleus Norepinephrine Axons and Increased Amyloid Beta Pathology in Male APP/PS1 Mice During Protracted Abstinence From Alcohol
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    pmc.ncbi.nlm.nih.gov/articles/PMC13009128/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Zolpidem restores sleep and decreases amyloid in a mouse model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12976976/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chronic Aerobic Exercise Alleviates Amyloid-induced Capillary Dysfunction
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    pmc.ncbi.nlm.nih.gov/articles/PMC12871324/
  17. www.sciencedirect.com www.sciencedirect.com
    Tanycytic degeneration impairs tau clearance and contributes to Alzheimer’s disease pathology
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    sciencedirect.com/science/article/pii/S3051383926000010
  18. www.sciencedirect.com www.sciencedirect.com
    Efficient amyloid-β degradation in Alzheimer’s disease using SPYTACs
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    sciencedirect.com/science/article/pii/S0092867426001625
  19. Feb 2026
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cry2 deficiency leads to cognitive impairment through the microbiota-gut-brain axis mediated S1P/NLRP3/IL-1β pathway in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12918613/
  21. Dec 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Near-lifespan mesoscopic optical imaging of cerebrovascular function reveals age and sex differences in preclinical Alzheimer’s disease model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12699225/
  23. www.biorxiv.org www.biorxiv.org
    Nuclear BIN1 isoforms regulate c-Myc-mediated cell cycle control in oligodendrocytes
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    biorxiv.org/content/10.1101/2025.09.30.676706v1
  24. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511472
  25. Nov 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comparative Investigation of the Retinal Phenotype of Three Mouse Models of Alzheimer's Disease With Optical Coherence Tomography
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    pmc.ncbi.nlm.nih.gov/articles/PMC12636989/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Progressive remote memory decline coincides with parvalbumin interneuron hyperexcitability and enhanced inhibition of cortical engram cells in a mouse model of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12638044/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Muscle Cathepsin B Treatment Improves Behavioral and Neurogenic Deficits in a Mouse Model of Alzheimer's Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12610946/
  29. Oct 2025
  30. www.spiedigitallibrary.org www.spiedigitallibrary.org
    LPS-induced systemic inflammation reduced sensory stimulation-evoked astrocyte Ca2+ without altering the vascular response in the APP/PS1dE9 mouse model
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    spiedigitallibrary.org/conference-proceedings-of-spie/13303/1330303/LPS-induced-systemic-inflammation-reduced-sensory-stimulation-evoked-astrocyte-Ca2/10.1117/12.3043431.full
  31. www.biorxiv.org www.biorxiv.org
    Repetitive mild traumatic brain injury causes neuronal damage in the APP/PS1 mouse model of Alzheimer’s disease without an enduring impact on amyloid pathology, sleep, or epileptiform activity
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    biorxiv.org/content/10.1101/2025.06.06.658157v1
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Copper overload worsens the inflammatory response of microglia to amyloid beta (Aβ) by impairing phagocytosis and promoting mitochondrial DNA-mediated NLRP3 inflammasome activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12495055/
  33. Sep 2025
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Zolpidem restores sleep and slows Alzheimer’s progression in a mouse model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12425003/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impaired hippocampal circuit function underlying memory encoding and consolidation precede robust Aβ deposition in a mouse model of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11160633/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Differences in Learning Strategy Selection and Object Location Memory Impairments in APP/PS1 Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12426418/
  37. www.biorxiv.org www.biorxiv.org
    Systemic inflammation reduces astrocyte Ca2+ and neurovascular coupling in a mouse model of Alzheimer’s disease
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    biorxiv.org/content/10.1101/2025.08.31.673380v1
  38. Aug 2025
  39. www.sciencedirect.com www.sciencedirect.com
    Positive Allosteric Modulation of M1 mAChRs with VU0486846 Reverses Cognitive Deficits in Male APPswe/PSEN1ΔE9 Alzheimer’s Mice
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    sciencedirect.com/science/article/pii/S0028390825003624
  40. www.sciencedirect.com www.sciencedirect.com
    Andrographolide modulates glucose metabolism in visceral adipose tissue in an Alzheimer's disease obese mouse model
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    sciencedirect.com/science/article/pii/S0021925825024585
  41. www.sciencedirect.com www.sciencedirect.com
    Reconstructed cell-type-specific rhythms in human brain link Alzheimer’s pathology, circadian stress, and ribosomal disruption
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    sciencedirect.com/science/article/pii/S0896627325005173
  42. www.science.org www.science.org
    A wearable spatiotemporal controllable ultrasonic device with amyloid-β disaggregation for continuous Alzheimer’s disease therapy
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    science.org/doi/10.1126/sciadv.adw1732
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A wearable spatiotemporal controllable ultrasonic device with amyloid-β disaggregation for continuous Alzheimer’s disease therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12309685/
  44. Jul 2025
  45. www.researchsquare.com www.researchsquare.com
    Cannabidiol modulates brain copper homeostasis in wild-type-like but not Alzheimer’s disease transgenic female mice: Implications for neuroprotective therapy
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    researchsquare.com/article/rs-6727849/v1
  46. link.springer.com link.springer.com
    Impaired hippocampal circuit function underlying memory encoding and consolidation precede robust Aβ deposition in a mouse model of alzheimer’s disease
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    link.springer.com/article/10.1038/s41598-025-05653-2
  47. Jun 2025
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer’s Disease Mouse Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12154612/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lecanemab Binds to Transgenic Mouse Model‐Derived Amyloid‐β Fibril Structures Resembling Alzheimer's Disease Type I, Type II and Arctic Folds
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    pmc.ncbi.nlm.nih.gov/articles/PMC12152531/
  50. Mar 2025
  51. onlinelibrary.wiley.com onlinelibrary.wiley.com
    CPNE7 Regulates Amyloidogenesis Through CAP1-Dependent ADAM10 Translation
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70026
  52. Feb 2025
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Muscle Cathepsin B treatment improves behavioral and neurogenic deficits in a mouse model of Alzheimer’s Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11785056/
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Regulation of cell distancing in peri-plaque glial nets by Plexin-B1 affects glial activation and amyloid compaction in Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11346591/
  55. Jan 2025
  56. molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com
    SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease
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    molecularneurodegeneration.biomedcentral.com/counter/pdf/10.1186/s13024-024-00788-8.pdf
  57. link.springer.com link.springer.com
    SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease
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    link.springer.com/article/10.1186/s13024-024-00788-8
  58. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225000112-main-html.html
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    52.53.155.43/f3927b613620da7ae9927001d3d9d5a924748cb9/1-s2.0-S2589004225000112-main-html.html
  59. Nov 2024
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vitamin C deficiency increases basal exploratory activity but decreases scopolamine-induced activity in APP/PSEN1 transgenic mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC2828687/
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PET neuroimaging studies of [18F]CABS13 in a double transgenic mouse model of Alzheimer’s disease and non-human primates
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    pmc.ncbi.nlm.nih.gov/articles/PMC4879824/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Wnt-induced activation of glucose metabolism mediates the in vivo neuroprotective roles of Wnt signaling in Alzheimer disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC7680578/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuroinflammation increases oxygen extraction in a mouse model of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11005245/
  64. Sep 2024
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early hippocampal hyperexcitability and synaptic reorganization in mouse models of amyloidosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11388185/
  66. Aug 2024
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology, cognition, and behavior in APP/PS1 mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11317949/
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chimeric antigen receptor macrophages target and resorb amyloid plaques
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    pmc.ncbi.nlm.nih.gov/articles/PMC11063938/
  69. www.frontiersin.org www.frontiersin.org
    LRRC25 expression during physiological aging and in mouse models of Alzheimer’s disease and iPSC-derived neurons
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    frontiersin.org/articles/10.3389/fnmol.2024.1365752
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sex-dependent effects of acute stress on amyloid-β in male and female mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC10232275/
  71. www.frontiersin.org www.frontiersin.org
    Acute stressors do not impair short-term memory or attention in an aged mouse model of amyloidosis
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    frontiersin.org/articles/10.3389/fnbeh.2023.1151833
  72. www.frontiersin.org www.frontiersin.org
    Region-specific heterogeneity in neuronal nuclear morphology in young, aged and in Alzheimer’s disease mouse brains
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    frontiersin.org/articles/10.3389/fcell.2023.1032504
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC7941983/
  74. Jul 2024
  75. molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com
    Astrocytic autophagy plasticity modulates Aβ clearance and cognitive function in Alzheimer’s disease
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    molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-024-00740-w
  76. May 2024
  77. www.frontiersin.org www.frontiersin.org
    Extracellular vesicles mediate inflammasome signaling in the brain and heart of Alzheimer’s disease mice
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    frontiersin.org/articles/10.3389/fnmol.2024.1369781
  78. Apr 2024
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Magnesium-L-threonate treats Alzheimer’s disease by modulating the microbiota-gut-brain axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11034594/
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    zpae022-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC11025629/
  81. www.sciencedirect.com www.sciencedirect.com
    Exercise-enhanced IGF1R sumoylation-induced nuclear translocation decreases neuroinflammation in alzheimer's mice
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    sciencedirect.com/science/article/pii/S2090123224001279
  82. www.sciencedirect.com www.sciencedirect.com
    The association of GNB5 with Alzheimer disease revealed by genomic analysis restricted to variants impacting gene function
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    sciencedirect.com/science/article/pii/S0002929724000053
  83. Jan 2024
  84. molecularbrain.biomedcentral.com molecularbrain.biomedcentral.com
    Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state
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    molecularbrain.biomedcentral.com/articles/10.1186/s13041-024-01076-8
  85. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's disease
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    onlinelibrary.wiley.com/doi/full/10.1111/acel.13895
  86. www.mdpi.com www.mdpi.com
    Evaluation of Novel B1R/B2R Agonists Containing TRIOZAN™ Nanoparticles for Targeted Brain Delivery of Antibodies in a Mouse Model of Alzheimer Disease
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    mdpi.com/1420-3049/28/13/5206
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sleep-Deep-Net learns sleep wake scoring from the end-user and completes each record in their style
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    pmc.ncbi.nlm.nih.gov/articles/PMC10769368/
  88. cmjournal.biomedcentral.com cmjournal.biomedcentral.com
    Kai-Xin-San protects against mitochondrial dysfunction in Alzheimer’s disease through SIRT3/NLRP3 pathway
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    cmjournal.biomedcentral.com/articles/10.1186/s13020-023-00722-y
  89. link.springer.com link.springer.com
    Natural and Pathological Aging Distinctively Impacts the Pheromone Detection System and Social Behavior
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    link.springer.com/article/10.1007/s12035-023-03362-3
  90. www.biorxiv.org www.biorxiv.org
    Neuroinflammation increases oxygen extraction in a mouse model of Alzheimer’s disease
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    biorxiv.org/content/10.1101/2023.10.16.562353v1
  91. www.mdpi.com www.mdpi.com
    CRMP2 Participates in Regulating Mitochondrial Morphology and Motility in Alzheimer’s Disease
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    mdpi.com/2073-4409/12/9/1287
  92. www.mdpi.com www.mdpi.com
    Multi-Targeting Intranasal Nanoformulation as a Therapeutic for Alzheimer’s Disease
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    mdpi.com/2218-273X/13/2/232
  93. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deletion of Small GTPase H-Ras Rescues Memory Deficits and Reduces Amyloid Plaque-Associated Dendritic Spine Loss in Transgenic Alzheimer’s Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC10771223/
  94. www.nature.com www.nature.com
    Cryo-EM of Aβ fibrils from mouse models find tg-APPArcSwe fibrils resemble those found in patients with sporadic Alzheimer’s disease
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    nature.com/articles/s41593-023-01484-4
  95. www.biorxiv.org www.biorxiv.org
    Cuprizone drives divergent neuropathological changes in different mouse models of Alzheimer’s disease
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    biorxiv.org/content/10.1101/2023.07.24.547147v1
  96. journals.plos.org journals.plos.org
    Two mouse models of Alzheimer’s disease accumulate amyloid at different rates and have distinct Aβ oligomer profiles unaltered by ablation of cellular prion protein
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    journals.plos.org/plosone/article
  97. Sep 2023
  98. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ligustilide-loaded liposome ameliorates mitochondrial impairments and improves cognitive function via the PKA/AKAP1 signaling pathway in a mouse model of Alzheimer's disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC10916432/
  99. Aug 2023
  100. www.sciencedirect.com www.sciencedirect.com
    MALDI mass spectrometry imaging discloses the decline of sulfoglycosphingolipid and glycerophosphoinositol species in the brain regions related to cognition in a mouse model of Alzheimer's disease
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    sciencedirect.com/science/article/pii/S0039914023007737
  101. May 2023
  102. www.mdpi.com www.mdpi.com
    DEAD-Box Helicase 17 Promotes Amyloidogenesis by Regulating BACE1 Translation
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    mdpi.com/2076-3425/13/5/745
  103. www.mdpi.com www.mdpi.com
    The Memory Benefit to Aged APP/PS1 Mice from Long-Term Intranasal Treatment of Low-Dose THC
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    mdpi.com/1422-0067/23/8/4253/htm
  104. Apr 2023
  105. www.biorxiv.org www.biorxiv.org
    Cryo-EM Structures of Amyloid-β Fibrils from Alzheimer’s Disease Mouse Models
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    biorxiv.org/content/10.1101/2023.03.30.534981v1
  106. Mar 2023
  107. www.biorxiv.org www.biorxiv.org
    Natural and pathological aging distinctively impact the vomeronasal detection system and social behavior
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    biorxiv.org/content/10.1101/2022.08.31.505522v4
  108. www.frontiersin.org www.frontiersin.org
    Trans ε-Viniferin Decreases Amyloid Deposits With Greater Efficiency Than Resveratrol in an Alzheimer’s Mouse Model
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    frontiersin.org/articles/10.3389/fnins.2021.803927/full
  109. www.science.org www.science.org
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  123. Jul 2022
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  125. Jun 2022
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  127. Apr 2022
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  132. Feb 2022
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  134. Nov 2021
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  136. Jul 2021
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  139. Jun 2021
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  142. May 2021
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  144. Mar 2021
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  146. Jan 2021
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  150. Dec 2020
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  152. Sep 2020
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  158. Jan 2020
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  162. Nov 2018
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    The conformational epitope for a new Aβ42 protofibril‐selective antibody partially overlaps with the peptide N‐terminal region
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