332 Matching Annotations
  1. Aug 2025
  2. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Transcriptomic Profiling of Small Molecule Atf6 Modulators in the Retina
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202501459R
  3. rupress.org rupress.org
    Perturbation of calreticulin potentiates CD8+ T cell–mediated antitumor immunity
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    rupress.org/jem/article/222/10/e20242360/278219/Perturbation-of-calreticulin-potentiates-CD8-T
  4. 52.53.155.43 52.53.155.43
    1-s2.0-S1556086425010196-main-html.html
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    52.53.155.43/f40ef8ae5f2bf3c83df319cd652be5efdc5714ac/1-s2.0-S1556086425010196-main-html.html
  5. 52.53.155.43 52.53.155.43
    russell-et-al-2025-cardiomyocyte-specific-larp6-overexpression-prevents-angiotensin-ii-induced-myocardial-dysfunction-html.html
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    52.53.155.43/cdc89213e8da95a53f691c27b85c44a7e3f558a7/russell-et-al-2025-cardiomyocyte-specific-larp6-overexpression-prevents-angiotensin-ii-induced-myocardial-dysfunction-html.html
  6. www.biorxiv.org www.biorxiv.org
    Cyclin-dependent kinase 9 inhibitors as oncogene signaling modulators in combination with targeted therapy for the treatment of colorectal cancer
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    biorxiv.org/content/10.1101/2025.08.13.669992v1
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CircMORC1 downregulated in plasma EVs promotes gastric cancer cell proliferation and invasion via miR-103a-1-5p sponging
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    pmc.ncbi.nlm.nih.gov/articles/PMC12344900/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Neutrophil Storage Pool in the Fetal Liver is the Principal Source of the Postnatal Neutrophil Surge
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    pmc.ncbi.nlm.nih.gov/articles/PMC12326356/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Oncogenic KRAS Mutations Confer a Unique Mechanotransduction Response to Peristalsis in Colorectal Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11802306/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations
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    pmc.ncbi.nlm.nih.gov/articles/PMC12319405/
  11. Jul 2025
  12. 52.53.155.43 52.53.155.43
    ssrn-5360566-html.html
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    52.53.155.43/c03b7c68b79b1d8db242c85c685d5735da740c17/ssrn-5360566-html.html
  13. www.nature.com www.nature.com
    Direct transdifferentiation of tumorigenic melanoma cells induces tumor cell reversion
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    nature.com/articles/s41419-025-07863-y
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RIT1 Drives Oncogenic Transformation and is an Actionable Target in Lung Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281470/
  15. www.biorxiv.org www.biorxiv.org
    Bi-allelic mutations in KCTD11 cause a new form of autosomal recessive intermediate Charcot-Marie-Tooth disease
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    biorxiv.org/content/10.1101/2025.06.30.661538v1
  16. www.sciencedirect.com www.sciencedirect.com
    Concerted changes in Epithelium and Stroma: a multi-scale, multi-omics analysis of progression from Barrett’s Esophagus to adenocarcinoma
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    sciencedirect.com/science/article/pii/S1534580725004125
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PICRUSt2 Analysis of Fecal Microbiome Associated With a Murine Model of Multiple Sclerosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12246385/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Uncovering novel lncRNAs linked to melanoma growth and migration with CRISPR-inhibition screening
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    pmc.ncbi.nlm.nih.gov/articles/PMC12238846/
  19. www.biorxiv.org www.biorxiv.org
    Parkinson’s disease microglia induce endogenous α-synuclein pathology in patient-specific midbrain organoids
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    biorxiv.org/content/10.1101/2025.07.01.662685v1
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12202856/
  21. www.sciencedirect.com www.sciencedirect.com
    Failed Cellular Surveillance Enables Pathogenic Matrix Deposition in a COL2A1-Related Osteoarthritis
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    sciencedirect.com/science/article/pii/S0021925825022860
  22. Jun 2025
  23. www.embopress.org www.embopress.org
    GPNMB marks a quiescent cell population in melanoma and promotes metastasis formation
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    embopress.org/doi/10.1038/s44319-025-00501-w
  24. www.embopress.org www.embopress.org
    lotti-et-al-gpnmb-marks-a-quiescent-cell-population-in-melanoma-and-promotes-metastasis-formation-html.html
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    embopress.org/doi/full/10.1038/s44319-025-00501-w
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiomic mapping of acquired chromosome 1 copy number and structural variants to identify therapeutic vulnerabilities in multiple myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12166981/
  26. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Deficiency of LPCAT3 Compromises Endometrial Stromal Cell Decidualization in Polycystic Ovary Syndrome
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202402967R
  27. 52.53.155.43 52.53.155.43
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  28. 52.53.155.43 52.53.155.43
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  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the Glucose–Insulin Link in Head and Neck Squamous Cell Carcinoma Induces Cytotoxic Oxidative Stress and Inhibits Cancer Growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12141995/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11611684/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TR-107, An Agonist of Caseinolytic Peptidase Proteolytic Subunit, Disrupts Mitochondrial Metabolism and Inhibits the Growth of Human Colorectal Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11614700/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutation of SMARCA4 Induces Cancer Cell–Intrinsic Defects in the Enhancer Landscape and Resistance to Immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12127800/
  33. May 2025
  34. www.sciencedirect.com www.sciencedirect.com
    The human proteome with direct physical access to DNA
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    sciencedirect.com/science/article/pii/S0092867425005070
  35. 52.53.155.43 52.53.155.43
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  36. www.nature.com www.nature.com
    Human endogenous retroviruses (HERVs) associated with glioblastoma risk and prognosis
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    nature.com/articles/s41417-024-00868-3
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antitumor CD4+ T Helper 1 Cells Target and Control the Outgrowth of Disseminated Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12046335/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GRB2 Promotes Malignant Behaviors of Breast Cancer by Modulating the Global Expression and Alternative Splicing Profiles in SK‐BR‐3 Cells Through Binding mRNA
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    pmc.ncbi.nlm.nih.gov/articles/PMC12086363/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Treatment Efficacy and Molecular Dynamics of Neoadjuvant Durvalumab and Olaparib in Resectable Urothelial Bladder Cancer: The NEODURVARIB Trial
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    pmc.ncbi.nlm.nih.gov/articles/PMC12010967/
  40. 52.53.155.43 52.53.155.43
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    52.53.155.43/5d34d403bb800062af64d4f86a93fcf038677ebf/PDF-html.html
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SHMT inhibitor synergizes with 5-Fu to suppress gastric cancer via cell cycle arrest and chemoresistance alleviation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12064653/
  42. 52.53.155.43 52.53.155.43
    1-s2.0-S152500162500382X-main-html.html
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  43. Apr 2025
  44. 52.53.155.43 52.53.155.43
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  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clinical and Translational Results from PORTER, a Multicohort Phase I Platform Trial of Combination Immunotherapy in Metastatic Castration-Resistant Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11995007/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interleukin-33 (IL-33) promotes DNA damage-resistance in lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11992107/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pre-existing skin-resident CD8 and γδ T cell circuits mediate immune response in Merkel cell carcinoma and predict immunotherapy efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11954000/
  48. Mar 2025
  49. 52.53.155.43 52.53.155.43
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    52.53.155.43/0c50db835b0879bd4ba6b171024f456815834163/PDF-html.html
  50. link.springer.com link.springer.com
    Roux-en-Y gastric bypass-associated fecal tyramine promotes colon cancer risk via increased DNA damage, cell proliferation, and inflammation
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    link.springer.com/article/10.1186/s40168-025-02049-2
  51. www.sciencedirect.com www.sciencedirect.com
    Integrated computational analysis identifies therapeutic targets with dual action in cancer cells and T cells
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    sciencedirect.com/science/article/pii/S107476132500072X
  52. Feb 2025
  53. 52.53.155.43 52.53.155.43
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    52.53.155.43/67a7c34effc3e448ea9dd7b8214065a7299b09a8/PDF-html.html
  54. www.sciencedirect.com www.sciencedirect.com
    Exogenous BMI1 expression aggravates oral squamous cell carcinomas in tongue epithelia
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    sciencedirect.com/science/article/pii/S1476558625000259
  55. www.sciencedirect.com www.sciencedirect.com
    Potentiating anti-tumor immunity by re-engaging immune synapse molecules
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    sciencedirect.com/science/article/pii/S2666379125000485
  56. aacrjournals.org aacrjournals.org
    MR1 gene and protein expression are enhanced by inhibition of the extracellular signal-regulated kinase ERK
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    aacrjournals.org/cancerimmunolres/article/12/10/1452/748716/MR1-Gene-and-Protein-Expression-Are-Enhanced-by
  57. www.sciencedirect.com www.sciencedirect.com
    CV1-secreting sCAR-T cells potentiate the abscopal effect of microwave ablation in heterogeneous tumors
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    sciencedirect.com/science/article/pii/S2666379125000382
  58. 52.53.155.43 52.53.155.43
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    52.53.155.43/b6e42261d11f7c0ae043c89c64cba240f59a1523/PDF-html.html
  59. aacrjournals.org aacrjournals.org
    A 5-hydroxymethylcytosine-based non-invasive model for early detection of colorectal carcinomas and advanced adenomas: the METHOD-2 study
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    aacrjournals.org/clincancerres/article/30/15/3337/746576/A-5-Hydroxymethylcytosine-Based-Noninvasive-Model
  60. aacrjournals.org aacrjournals.org
    Attenuation of sialylation augments antitumor immunity and improves response to immunotherapy in ovarian cancer
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    aacrjournals.org/cancerres/article/83/13/2171/727429/Attenuation-of-Sialylation-Augments-Antitumor
  61. www.biorxiv.org www.biorxiv.org
    Repurposing statins and phenothiazines to treat chemoresistant neuroblastoma
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    biorxiv.org/content/10.1101/2025.01.28.635193v1
  62. Jan 2025
  63. www.sciencedirect.com www.sciencedirect.com
    Phenotypic plasticity and increased infiltration of peripheral blood-derived TREM1+ mono-macrophages following radiotherapy in rectal cancer
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    sciencedirect.com/science/article/pii/S266637912400658X
  64. Dec 2024
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting ketone body metabolism in mitigating gemcitabine resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC11665555/
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dominant-negative TP53 mutations potentiated by the HSF1-regulated proteostasis network
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    pmc.ncbi.nlm.nih.gov/articles/PMC11565964/
  67. www.mdpi.com www.mdpi.com
    Pan-Cancer Insights: A Study of Microbial Metabolite Receptors in Malignancy Dynamics
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    mdpi.com/2072-6694/16/24/4178
  68. www.sciencedirect.com www.sciencedirect.com
    DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states
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    sciencedirect.com/science/article/pii/S1097276524009146
  69. Nov 2024
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drug prioritization identifies panobinostat as a tailored treatment element for patients with metastatic hepatoblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11556140/
  71. www.biorxiv.org www.biorxiv.org
    Human cartilage model of the precocious osteoarthritis-inducing COL2A1 p.Arg719Cys reveals pathology-driving matrix defects and a failure of the ER proteostasis network to recognize the defective procollagen-II
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    biorxiv.org/content/10.1101/2024.11.07.622468v1
  72. Sep 2024
  73. www.biorxiv.org www.biorxiv.org
    A Comprehensive Proteogenomic and Spatial Analysis of Innate and Acquired Resistance of Metastatic Melanoma to Immune Checkpoint Blockade Therapies
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    biorxiv.org/content/10.1101/2024.09.12.612675v1
  74. www.sciencedirect.com www.sciencedirect.com
    RCC1 regulation of subcellular protein localization via Ran GTPase drives pancreatic ductal adenocarcinoma growth
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    sciencedirect.com/science/article/pii/S0304383524006700
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Proteogenomics of Prostate Cancer Radioresistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC11411600/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EWS-FLI1 and Activator Protein-1 (AP-1) Reciprocally Regulate Extracellular-Matrix Proteins in Ewing sarcoma Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11354993/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11372367/
  78. aacrjournals.org aacrjournals.org
    Aberrant L-Fucose accumulation and increased core fucosylation are metabolic liabilities in mesenchymal glioblastoma
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    aacrjournals.org/cancerres/article/83/2/195/715074/Aberrant-L-Fucose-Accumulation-and-Increased-Core
  79. www.sciencedirect.com www.sciencedirect.com
    GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant
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    sciencedirect.com/science/article/pii/S1535610824003052
  80. Aug 2024
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Potentiating Salvage Radiotherapy in Radiorecurrent Prostate Cancer Through Anti-CTLA4 Therapy: Implications from a Syngeneic Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC11352774/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterizing Relationships between T-cell Inflammation and Outcomes in Patients with High-Risk Neuroblastoma According to Mesenchymal and Adrenergic Signatures
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    ncbi.nlm.nih.gov/pmc/articles/PMC11350481/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Contribution and Clinical Implication of Cancer-Associated Fibroblasts in Glioblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10922678/
  84. www.biorxiv.org www.biorxiv.org
    Dominant Malignant Clones Leverage Lineage Restricted Epigenomic Programs to Drive Ependymoma Development
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    biorxiv.org/content/10.1101/2024.08.12.607603v1
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p53R172H and p53R245W Hotspot Mutations Drive Distinct Transcriptomes in Mouse Mammary Tumors Through a Convergent Transcriptional Mediator
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    ncbi.nlm.nih.gov/pmc/articles/PMC11310746/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor Vessel Normalization via PFKFB3 Inhibition Alleviates Hypoxia and Increases Tumor Necrosis in Rectal Cancer upon Radiotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11310748/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The BET PROTAC inhibitor GNE-987 displays anti-tumor effects by targeting super-enhancers regulated gene in osteosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292958/
  88. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transcriptomic analysis of the hippocampus from six inbred strains of mice suggests a basis for sex‐specific susceptibility and severity of neurological disorders
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    onlinelibrary.wiley.com/doi/10.1002/cne.23989/full
  89. Jul 2024
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11275559/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LncRNA CARMN m6A demethylation by ALKBH5 inhibits mutant p53‐driven tumour progression through miR‐5683/FGF2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11263751/
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ER procollagen storage defect without coupled unfolded protein response drives precocious arthritis
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  131. Nov 2023
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  135. Oct 2023
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  144. Aug 2023
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  184. Feb 2023
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  188. Jan 2023
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  194. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  207. Sep 2022
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  213. Aug 2022
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  220. Jul 2022
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  222. Jun 2022
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  228. May 2022
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    Comprehensive profiling of myxopapillary ependymomas identifies a distinct molecular subtype with relapsing disease
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