76 Matching Annotations
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    Efficacy of ATR Kinase Inhibitor Elimusertib Monotherapy or Combination in Tumors with DNA Damage Response Pathway and Other Genomic Alterations
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  3. Aug 2025
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    Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations
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  5. Jul 2025
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    Clinical Significance of TERT Promoter Mutations in Neuroblastoma
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    Shared genomic features of HIV+ diffuse large B-cell lymphoma in two African cohorts
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    Genomic and epigenomic analysis of plasma cell-free DNA identifies stemness features associated with worse survival in lethal prostate cancer
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  9. Jun 2025
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    Spatial–Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune Microenvironment
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    Aged and BRCA-Mutated Stromal Cells Drive Epithelial Cell Transformation
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  12. May 2025
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    Auditory neuropathy spectrum disorder and related auditory features in patients with hearing loss associated with the MT-TS1 m.7471dup variant
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    Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes
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  15. Apr 2025
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    Germline Pathogenic DROSHA Variants Are Linked to Pineoblastoma and Wilms Tumor Predisposition
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    A Genomics-Driven Artificial Intelligence-Based Model Classifies Breast Invasive Lobular Carcinoma and Discovers CDH1 Inactivating Mechanisms
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  18. Feb 2025
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    DNA methylation profiling identifies subgroups of lung adenocarcinoma with distinct immune cell composition, DNA methylation age, and clinical outcome
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    Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy
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    Whole genome sequencing powered ctDNA sequencing for breast cancer detection
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  23. Jan 2025
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    Targeting PRMT1 Reduces Cancer Persistence and Tumor Relapse in EGFR- and KRAS-Mutant Lung Cancer
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    Sex disparities in the association between rare earth elements exposure and genetic mutation frequencies in lung cancer patients
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    Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma
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  28. Dec 2024
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    Comprehensive genomic characterization of hematologic malignancies at a pediatric tertiary care center
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  30. Nov 2024
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  32. Oct 2024
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    Clinical Outcome–Related Mutational Signatures Identified by Integrative Genomic Analysis in Nasopharyngeal Carcinoma
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  34. Sep 2024
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    Novel ERBB2 Variant Potentially Associated with Resistance against Anti-HER2 Monoclonal Antibody–Based Therapy in ERBB2-Amplified Metastatic Colorectal Cancer
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    Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression
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  37. Jul 2024
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    Integrating Multisector Molecular Characterization into Personalized Peptide Vaccine Design for Patients with Newly Diagnosed Glioblastoma
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  39. Jun 2024
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    Tumour microenvironment programming by an RNA–RNA-binding protein complex creates a druggable vulnerability in IDH-wild-type glioblastoma
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  41. May 2024
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    Discovery of a novel potent EGFR inhibitor against EGFR activating mutations and on-target resistance in NSCLC
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    Integrative molecular analyses of the MD Anderson prostate cancer patient-derived xenograft (MDA PCa PDX) series
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  44. Mar 2024
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    Follicular lymphoma B cells exhibit heterogeneous transcriptional states with associated somatic alterations and tumor microenvironments
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  46. Feb 2024
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    The Immunogenomic Landscape of Neuroendocrine Prostate Cancer
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  49. Jan 2024
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    Leveraging tissue-specific enhancer-target gene regulatory networks identifies enhancer somatic mutations that functionally impact lung cancer
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  51. Dec 2023
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    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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  54. Nov 2023
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    Unveiling the metal mutation nexus: Exploring the genomic impacts of heavy metal exposure in lung adenocarcinoma and colorectal cancer
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    Clinical and Molecular Features of Long-term Response to Immune Checkpoint Inhibitors in Patients with Advanced Non–Small Cell Lung Cancer
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  57. Oct 2023
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    Neoantigen targetability in progressive advanced melanoma
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  60. Sep 2023
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    Identifying mechanisms of resistance by circulating tumour DNA in EVOLVE, a Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer at time of PARP Inhibitor Progression
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  62. Aug 2023
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    Early clonal extinction in glioblastoma progression revealed by genetic barcoding
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  65. Jul 2023
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  67. Jun 2023
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids
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    Genomic and Transcriptomic Analysis of Relapsed and Refractory Childhood Solid Tumors Reveals a Diverse Molecular Landscape and Mechanisms of Immune Evasion
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    Clinical Efficacy and Whole Exome Sequencing of Liquid Biopsies in a Phase IB/II study of Bazedoxifene and Palbociclib in Advanced Hormone Receptor-Positive Breast Cancer
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  71. Feb 2023
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    A molecular phenotypic map of malignant pleural mesothelioma
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  73. Jan 2023
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    Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors
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  75. Aug 2022
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  77. Jul 2022
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    Spatiotemporal genomic analysis reveals distinct molecular features in recurrent stage I non-small cell lung cancers
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  79. Jun 2022
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    Quantification of neoantigen-mediated immunoediting in cancer evolution
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    aacrjournals.org/cancerres/article/82/12/2226/699353/Quantification-of-Neoantigen-Mediated
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    Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
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    Predictive markers of response to neoadjuvant durvalumab with nab-paclitaxel and dose dense doxorubicin/cyclophosphamide in basal-like triple negative breast cancer
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  83. Apr 2022
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    Bone marrow surveillance of pediatric cancer survivors identifies clones that predict therapy-related leukemia
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  85. Feb 2022
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    Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target
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  87. Dec 2021
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    Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight
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  89. Oct 2021
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    Prediction of Immunotherapy Response in Melanoma through Combined Modeling of Neoantigen Burden and Immune-Related Resistance Mechanisms
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  91. Aug 2021
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    Genomic characterization of de novo metastatic breast cancer
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  93. Jul 2021
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    Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
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    Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
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  96. Mar 2021
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    Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery
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  98. Sep 2020
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    Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer
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  100. Jan 2020
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    A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity
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  102. Nov 2018
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    The Polyploid State Plays a Tumor-Suppressive Role in the Liver
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    Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma
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    Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups
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    Integrated Genomic Analysis of Hürthle Cell Cancer Reveals Oncogenic Drivers, Recurrent Mitochondrial Mutations, and Unique Chromosomal Landscapes
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    Characterization of BK Polyomaviruses from Kidney Transplant Recipients Suggests a Role for APOBEC3 in Driving In-Host Virus Evolution
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    Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing
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    Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair
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    Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma
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  112. Nov 2017
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    Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient
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    Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia
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