171 Matching Annotations
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    Spatial Profiling Identifies Regionally Distinct Microenvironments and Targetable Immunosuppressive Mechanisms in Pediatric Osteosarcoma Pulmonary Metastases
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    LAMP2A regulates endosomal protein composition and membrane identity in exosome biogenesis
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  4. Nov 2025
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    KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma
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    Exposure to the trichloroethylene metabolite S-(1,2-dichlorovinyl)-L-cysteine under hypoxic conditions (%O2 =2%) alters differential gene expression and mitigates decreased invasion capacity, compared to normoxic conditions (%O2 ≥ 21%) in HTR-8/SVneo cells
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  7. Oct 2025
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    Human heart-macrophage assembloids mimic immune-cardiac interactions and enable arrhythmia disease modeling
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    Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis
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    Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility
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    Database analysis reveals endophilin A expression as a marker of metastasis and prognosis in breast cancer
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    Non-cell-autonomous tumor promotion in DICER1 cancer predisposition
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  13. Sep 2025
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    IGF2BP3 redirects glycolytic flux to promote one-carbon metabolism and RNA methylation
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    Reproducibility of PD patient-specific midbrain organoid data for in vitro disease modeling
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    Reference genome choice compromises population genetic analyses
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    Anticancer effects of 6-diazo-5-oxo-L-norleucine (DON)-loaded PLGA nanoparticles in triple-negative breast cancer by inhibiting glutamine metabolism: An integrated bioinformatic and experimental approach
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    The Ubiquitin–Proteasome System is an Important Driver of EBV-Associated Nasopharyngeal Carcinoma Progression: A Meta-Analysis of Transcriptomics Data
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    Chronic hyperactivation of midbrain dopamine neurons causes preferential dopamine neuron degeneration
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  20. Aug 2025
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    Endocardial primary cilia and blood flow regulate EndoMT during endocardial cushion development
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    Blocking NRF2 Translation by Inhibition of Cap-Dependent Initiation Sensitizes Lymphoma Cells to Ferroptosis and CAR T-cell Immunotherapy
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    Evaluating Gene Fusions as Prognostic Biomarkers and Therapeutic Targets in Immune Checkpoint Blockade-Treated Advanced Melanoma: a Retrospective Analysis.
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    Reconstructed cell-type-specific rhythms in human brain link Alzheimer’s pathology, circadian stress, and ribosomal disruption
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  25. Jul 2025
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    Cellular crosstalk mediated by TGF-β drives epithelial-mesenchymal transition in patient-derived multi-compartment biliary organoids
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    Complete loss of PAX4 causes transient neonatal diabetes in humans
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    Developmental pyrethroid exposure disrupts molecular pathways for MAP kinase and circadian rhythms in mouse brain
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    Parkinson’s disease microglia induce endogenous α-synuclein pathology in patient-specific midbrain organoids
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    The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
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    Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer
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  32. Jun 2025
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    An organ-chip model of sporadic ALS using iPSC-derived spinal cord motor neurons and an integrated blood-brain-like barrier
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    Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics
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  36. May 2025
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    Epigenetic Plasticity Drives Carcinogenesis and Multi-Therapy Resistance in Multiple Myeloma
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    Complete Loss of PAX4 causes Transient Neonatal Diabetes in Humans
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  39. Apr 2025
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    GeneSetCart: assembling, augmenting, combining, visualizing, and analyzing gene sets
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    Brain-wide mapping of immune receptors uncovers a neuromodulatory role of IL-17E and the receptor IL-17RB
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    Augmenting CAR T Cell Functions with LIGHT
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  44. Mar 2025
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    Characterization of the Temporal Dynamics of the Endothelial–Mesenchymal-like Transition Induced by Soluble Factors from Dengue Virus Infection in Microvascular Endothelial Cells
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    Outer radial glia promotes white matter regeneration after neonatal brain injury
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  47. Feb 2025
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    NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome
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  49. Jan 2025
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    Steatohepatitis-induced vascular niche alterations promote melanoma metastasis
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    The Functional Transcriptomic Landscape Informs Therapeutic Strategies in Multiple Myeloma
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    Single-Cell RNA Sequencing before and after Light Chain Escape Reveals Intrapatient Multiple Myeloma Subpopulations with Divergent Osteolytic Gene Expression
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  53. Dec 2024
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    Single-Cell Analysis of Bone Marrow CD8+ T Cells in Myeloid Neoplasms Reveals Pathways Associated with Disease Progression and Response to Treatment with Azacitidine
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  55. Nov 2024
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    How the liver transcriptome and lipid composition influence the progression of nonalcoholic fatty liver disease to hepatocellular carcinoma in a murine model
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    Drug prioritization identifies panobinostat as a tailored treatment element for patients with metastatic hepatoblastoma
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  60. Oct 2024
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    Quiescence and aging of melanocyte stem cells and a novel association with PD-L1
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  62. Sep 2024
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    Sex-dependent differences in the ability of nicotine to modulate discrimination learning and cognitive flexibility in mice
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    Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation
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    EWS-FLI1 and Activator Protein-1 (AP-1) Reciprocally Regulate Extracellular-Matrix Proteins in Ewing sarcoma Cells
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  67. Aug 2024
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    The Lactate Receptor GPR81 is a Mechanism of Leukemia-Associated Macrophage Polarization in the Bone Marrow Microenvironment
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  70. Jul 2024
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    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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  72. Jun 2024
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    Islet cell stress induced by insulin-degrading enzyme deficiency promotes regeneration and protection from autoimmune diabetes
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    Potential molecular patterns for tuberculosis susceptibility in diabetic patients with poor glycaemic control: a pilot study
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  75. May 2024
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    Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects
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    Tumor niche network-defined subtypes predict immunotherapy response of esophageal squamous cell cancer
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    Metabolic regulator ERRγ governs gastric stem cell differentiation into acid-secreting parietal cells
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    A phosphate transporter in VIPergic neurons of the suprachiasmatic nucleus gates locomotor activity during the light/dark transition in mice
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  80. Apr 2024
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    Chronic hyperactivation of midbrain dopamine neurons causes preferential dopamine neuron degeneration
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    Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells
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    Developmental pyrethroid exposure disrupts molecular pathways for MAP kinase and circadian rhythms in mouse brain
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  85. Mar 2024
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    Proteomic analysis shows decreased type I fibers and ectopic fat accumulation in skeletal muscle from women with PCOS
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  87. Feb 2024
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    Sustained antidepressant effects of ketamine metabolite involve GABAergic inhibition-mediated molecular dynamics in aPVT glutamatergic neurons
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    biorxiv.org/content/10.1101/2023.12.19.571978v1
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    The Immunogenomic Landscape of Neuroendocrine Prostate Cancer
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  91. Jan 2024
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    Discrete prefrontal neuronal circuits determine repeated stress-induced behavioral phenotypes in male mice
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  93. Nov 2023
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    Truncated radial glia as a common precursor in the late corticogenesis of gyrencephalic mammals
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    Structured wound angiogenesis instructs mesenchymal barrier compartments in the regenerating nerve
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    Integrated Network Analysis of microRNAs, mRNAs, and Proteins Reveals the Regulatory Interaction between hsa-mir-200b and CFL2 Associated with Advanced Stage and Poor Prognosis in Patients with Intestinal Gastric Cancer
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  97. Oct 2023
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    Chromatin accessibility landscape of human triple-negative breast cancer cell lines reveals variation by patient donor ancestry
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  99. Sep 2023
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    TGS1/PIMT knockdown reduces lipid accumulation in adipocytes, limits body weight gain and promotes insulin sensitivity in mice
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    CRISPR/Cas9-mediated activation of NR5A1 steers female human embryonic stem cell-derived bipotential gonadal-like cells towards a steroidogenic cell fate
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  102. Aug 2023
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    Circadian modulation by time-restricted feeding rescues brain pathology and improves memory in mouse models of Alzheimer’s disease
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    Overcome Prostate Cancer Resistance to Immune Checkpoint Therapy with Ketogenic Diet-Induced Epigenetic Reprogramming
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    Original research: Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma
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  106. Jul 2023
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    The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina
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    Stromal-induced epithelial-mesenchymal transition induces targetable drug resistance in acute lymphoblastic leukemia
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    Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks
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    MEF2A suppresses stress responses that trigger DDX41-dependent IFN production
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    Obesity during preclinical Alzheimer's disease development exacerbates brain metabolic decline
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  112. Jun 2023
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    hdWGCNA identifies co-expression networks in high-dimensional transcriptomics data
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