104 Matching Annotations
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    STK11 mutations and deletions define a distinct subtype of cervical adenocarcinoma
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    Functional footprints of homologous recombination deficiency in prostate cancer revealed by ctDNA fragmentation and transcription factor accessibility
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    nature.com/articles/s41416-025-03301-0
  4. Jan 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Assessment of Circulating Tumor DNA for Early Detection of Hepatocellular Carcinoma in Alpha‐Fetoprotein–Negative Patients With Cirrhotic Nodules
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  6. Dec 2025
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    Personalized ctDNA detection and genomic profiling in the NeoRHEA Study
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    nature.com/articles/s41523-025-00852-6
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    Extrachromosomal circular miRNA-gene amplifications contribute to the renal cancer phenotype
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    sciencedirect.com:5037/science/article/pii/S2211124725014329
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    Cancer Genomic Alterations and Microenvironmental Features Encode Synergistic Interactions with Disease Outcomes
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    Long-term Survival and Molecular Biomarker Evaluation of a Phase II Cetuximab and Nivolumab Clinical Trial in Recurrent/Metastatic Head and Neck Cancer
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  11. Nov 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DLBCL Cells Emerge after CD19 CAR T Cells with Cross-Antigen Resistance and a Gene Signature Predictive of Clinical CAR T-cell Response
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    Dynamics of Mutant Hematopoietic Progenitor Cells Are Not Associated with Clinical Outcomes in Multiple Myeloma
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    Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
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  15. Oct 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genomic and Immune Landscape of Pancreatic Ductal Adenocarcinoma Associated with Germline Pathogenic Variants in ATM
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  17. Sep 2025
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    Molecular basis of DNA recognition by the HMG-box-C1 module of capicua
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    Loss of Sorting Nexin 10 accelerates KRAS-induced pancreatic tumorigenesis
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    Phenotypic pleiotropy of missense variants in human B cell confinement receptor P2RY8
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    sciencedirect.com/science/article/pii/S2666979X2500237X
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    Mutagenic Impact and Evolutionary Influence of Chemoradiotherapy in Hematologic Malignancies
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    Detection of human brain cancers using genomic and immune cell characterization of cerebrospinal fluid through CSF-BAM
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    Cemiplimab in locally advanced or metastatic secondary angiosarcomas (CEMangio): A phase II clinical trial and biomarker analyses
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    Plasma exosomes from individuals with type 2 diabetes drive breast cancer aggression in patient-derived organoids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12381303/
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    GPSai: A Clinically Validated AI Tool for Tissue of Origin Prediction During Routine Tumor Profiling
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  26. Jun 2025
  27. 52.53.155.43 52.53.155.43
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    Aged and BRCA-Mutated Stromal Cells Drive Epithelial Cell Transformation
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  30. May 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inferring Drug–Gene Relationships in Cancer Using Literature-Augmented Large Language Models
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  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
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    Social, behavioral and clinical risk factors are associated with clonal hematopoiesis
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    The genomic landscape of benign and malignant thyroid tumors from individuals carrying germline PTEN variants is distinct from sporadic thyroid cancers
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  35. Apr 2025
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    A Genomics-Driven Artificial Intelligence-Based Model Classifies Breast Invasive Lobular Carcinoma and Discovers CDH1 Inactivating Mechanisms
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    Establishing a comprehensive panel of patient-derived xenograft models for high-grade endometrial carcinoma: molecular subtypes, genetic alterations, and therapeutic target profiling
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    Genomic Profiling to Contextualize the Results of Intervention for Smoldering Multiple Myeloma
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  40. Mar 2025
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune Checkpoint Blockade Delays Cancer Development and Extends Survival in DNA Polymerase Mutator Syndromes
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  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impact of Co-mutations and Transcriptional Signatures in Non–Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial
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  43. Feb 2025
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    Effect of MisMatch repair deficiency on metastasis occurrence in a syngeneic mouse model
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  45. aacrjournals.org aacrjournals.org
    Multiomics Profiling Distinguishes Sebaceous Carcinoma from Benign Sebaceous Neoplasms and Provides Insight into the Genetic Evolution of Sebaceous Carcinogenesis
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    Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy
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  47. Jan 2025
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    Predisposition footprints in the somatic genome of Wilms tumours
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  51. Dec 2024
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    Exploiting NRF2-ARE pathway activation in papillary renal cell carcinoma
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    Pan-Cancer Insights: A Study of Microbial Metabolite Receptors in Malignancy Dynamics
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  54. Nov 2024
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular and modular intricacies of precision oncology
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  56. Oct 2024
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical value of liquid biopsy in FGFR2 fusion-positive cholangiocarcinoma patients during targeted therapy
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    Clinical Outcome–Related Mutational Signatures Identified by Integrative Genomic Analysis in Nasopharyngeal Carcinoma
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  59. Sep 2024
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural analysis of genomic and proteomic signatures reveal dynamic expression of intrinsically disordered regions in breast cancer
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    Novel ERBB2 Variant Potentially Associated with Resistance against Anti-HER2 Monoclonal Antibody–Based Therapy in ERBB2-Amplified Metastatic Colorectal Cancer
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    Activating mTOR mutations are detrimental in nutrient-poor conditions
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  63. Aug 2024
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mTORC1-driven protein translation correlates with clinical benefit of capivasertib within a genetically preselected cohort of PIK3CA-altered tumours
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    Transient Differentiation-State Plasticity Occurs During Acute Lymphoblastic Leukemia Initiation
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  67. Jul 2024
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  69. Jun 2024
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    Early detection and diagnosis of cancer with interpretable machine learning to uncover cancer-specific DNA methylation patterns
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  71. May 2024
  72. aacrjournals.org aacrjournals.org
    Negative hyperselection of resistance mutations for panitumumab maintenance in RAS wild-type metastatic colorectal cancer (PanaMa phase II trial, AIO KRK 0212)
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  74. Apr 2024
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    Co-mutations and KRAS G12C inhibitor efficacy in advanced NSCLC
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  76. Mar 2024
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    A novel type of monocytic leukemia stem cell revealed by the clinical use of venetoclax-based therapy
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  78. Feb 2024
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    Active natural compounds perturb the melanoma risk-gene network
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  81. Jan 2024
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    Leveraging tissue-specific enhancer-target gene regulatory networks identifies enhancer somatic mutations that functionally impact lung cancer
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  83. Dec 2023
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  85. Nov 2023
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    Population-specific Mutation Patterns in Breast Tumors from African American, European American, and Kenyan Patients
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    Clinical and Molecular Features of Long-term Response to Immune Checkpoint Inhibitors in Patients with Advanced Non–Small Cell Lung Cancer
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  88. Jul 2023
  89. www.nature.com www.nature.com
    The tumor suppressor CREBBP and the oncogene MYCN cooperate to induce malignant brain tumors in mice
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  90. Jun 2023
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    Microsatellite instability states serve as predictive biomarkers for tumors chemotherapy sensitivity
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The immunopeptidome from a genomic perspective: Establishing the non-canonical landscape of MHC class I–associated peptides
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    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
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  95. May 2023
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    The immunopeptidome from a genomic perspective: Establishing the non-canonical landscape of MHC class I-associated peptides.
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    Mutational Landscape of CEBPA in Mexican Pediatric Acute Myeloid Leukemia Patients: Prognostic Implications
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  98. Feb 2023
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive genomic profiling of upper tract urothelial carcinoma and urothelial carcinoma of the bladder identifies distinct molecular characterizations with potential implications for targeted therapy & immunotherapy
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A molecular phenotypic map of malignant pleural mesothelioma
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  101. Jan 2023
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human metastatic cholangiocarcinoma patient-derived xenografts and tumoroids for preclinical drug evaluation
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative Genomics Provides Etiologic and Biological Insight into Melanoma Subtypes
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  104. Dec 2022
  105. aacrjournals.org aacrjournals.org
    Treatment represents a key driver of metastatic cancer evolution
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    aacrjournals.org/cancerres/article/82/16/2918/707589/Treatment-Represents-a-Key-Driver-of-Metastatic
  106. Sep 2022
  107. f1000research.com f1000research.com
    F1000Research Article: Identification of prognostic biomarkers of invasive ductal carcinoma by an integrated bioinformatics approach.
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  108. Aug 2022
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  110. Jul 2022
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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoadjuvant chemotherapy induces genomic and transcriptomic changes in ovarian cancer
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  113. Jun 2022
  114. link.springer.com link.springer.com
    Serial Tumor Molecular Profiling of Newly Diagnosed HER2-Negative Breast Cancers During Chemotherapy in Combination with Angiogenesis Inhibitors
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    link.springer.com/article/10.1007/s11523-022-00886-x
  115. aacrjournals.org aacrjournals.org
    Predictive markers of response to neoadjuvant durvalumab with nab-paclitaxel and dose dense doxorubicin/cyclophosphamide in basal-like triple negative breast cancer
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    aacrjournals.org/clincancerres/article/28/12/2587/699273/Predictive-Markers-of-Response-to-Neoadjuvant
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Mutational Signature Comprehensive Analysis Toolkit (musicatk) for the discovery, prediction, and exploration of mutational signatures
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    ncbi.nlm.nih.gov/pmc/articles/PMC8639789/
  117. May 2022
  118. aacrjournals.org aacrjournals.org
    Single cell characterization of the cellular landscape of acral melanoma identifies novel targets for immunotherapy
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deconvoluting mechanisms of acquired resistance to RAF inhibitors in BRAF V600E mutant human glioma
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  120. aacrjournals.org aacrjournals.org
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  121. Apr 2022
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  123. Dec 2021
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  125. Aug 2021
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    Interaction between Ras and Src clones causes interdependent tumor malignancy via Notch signaling in Drosophila
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  128. Jul 2021
  129. europepmc.org europepmc.org
    A homozygous FANCM mutation underlies a familial case of non-syndromic primary ovarian insufficiency.
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  130. Jun 2021
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    Estrogen receptor α (ERα)-binding super-enhancers drive key mediators that control uterine estrogen responses in mice
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  132. May 2021
  133. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Bladder tumor subtype commitment occurs in carcinoma in-situ driven by key signaling pathways including ECM remodeling
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    Comprehensive analysis of genomic alterations, clinical outcomes, putative functions and potential therapeutic value of MMP11 in human breast cancer
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  135. Apr 2021
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  137. Mar 2021
  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Triple-Negative Essential Thrombocythemia: Clinical-Pathological and Molecular Features. A Single-Center Cohort Study
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    Germline EGFR variants are over-represented in adolescents and young adults (AYA) with adrenocortical carcinoma
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  140. Jan 2020
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    Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome
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    A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity
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  144. Nov 2018
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    Cell Model Passports—a hub for clinical, genetic and functional datasets of preclinical cancer models
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  146. Nov 2017
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    A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC)
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