142 Matching Annotations
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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SPEN inactivation drives resistance to androgen receptor pathway inhibitors in metastatic prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13563593/
  3. www.nature.com www.nature.com
    Switches in alternatively spliced isoforms impact protein and drug interactions in melanoma, ovarian cancer, and acute myeloid leukemia
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    nature.com/articles/s41416-026-03638-0
  4. Oct 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular underpinnings of metastatic small renal masses
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    pmc.ncbi.nlm.nih.gov/articles/PMC13596717/
  6. Sep 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    STK11 Mutations and Deletions Define an Aggressive Molecular Subgroup of Cervical Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13547848/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Efficacy and Genomic Analysis of HER2-Mutant Metastatic Triple-Negative Breast Cancer Treated with Neratinib Alone or with Trastuzumab in the SUMMIT Basket Trial
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    pmc.ncbi.nlm.nih.gov/articles/PMC13530984/
  9. 54.241.53.176 54.241.53.176
    ccr-26-0805-html.html
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  10. Aug 2026
  11. 54.241.53.176 54.241.53.176
    ccr-25-4135-html.html
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    54.241.53.176/1b09fed9ed8c20316de4798608469490491dee06/ccr-25-4135-html.html
  12. aacrjournals.org aacrjournals.org
    Integrated Multiomic Profiling Enhances Risk Stratification and Prognostication in Canine Osteosarcoma
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    aacrjournals.org/clincancerres/article/32/16/3668/787332/Integrated-Multiomic-Profiling-Enhances-Risk
  13. Jul 2026
  14. aacrjournals.org aacrjournals.org
    Uniform processing of diverse sequencing data: A cross-population comparison of colon cancer genomic landscapes from The Cancer Genome Atlas and a Chinese cohort
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    aacrjournals.org/cebp/article/35/5/762/784356/Uniform-Processing-of-Diverse-Sequencing-Data-A
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Pan-Tumor Landscape of Gene Amplifications and Copy Number Amplification Ratio for Established and Emerging Clinical Targets
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    pmc.ncbi.nlm.nih.gov/articles/PMC13320176/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular and immune landscape of recurrent and/or distant metastatic squamous cell carcinoma of the head and neck: an EORTC/IMMUCAN project
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    pmc.ncbi.nlm.nih.gov/articles/PMC13320198/
  17. www.biorxiv.org www.biorxiv.org
    A comprehensive analysis of calreticulin mutants reveals distinct biophysicochemical proprieties with a potential for refined targeted therapies
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    biorxiv.org/content/10.64898/2026.06.19.733337v1
  18. Jun 2026
  19. aacrjournals.org aacrjournals.org
    Genomic and transcriptomic analysis of high-grade endometrial carcinoma reveals biological heterogeneity and molecular classification challenges
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    aacrjournals.org/cancerrescommun/article/6/4/961/784451/Genomic-and-Transcriptomic-Analysis-of-High-Grade
  20. aacrjournals.org aacrjournals.org
    The Impact of Concordance Between Liquid and Tissue Biopsy for Actionable Mutations: Insights from the Rome Trial
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    aacrjournals.org/clincancerres/article/32/1/45/771258/The-Impact-of-Concordance-between-Liquid-and
  21. May 2026
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Contrasting Features of Papillary and Chromophobe Renal Cell Carcinoma Revealed by Whole-Genome Sequencing
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    pmc.ncbi.nlm.nih.gov/articles/PMC13136883/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Out-of-frame CBX3::ALK fusion drives ALK activation and therapy response
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    pmc.ncbi.nlm.nih.gov/articles/PMC13130619/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Genomically Tailored Multiagent Precision Medicine Clinical Trial for Adults with Recurrent Glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133611/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    plasmaCHORD: A Machine Learning Approach to Distinguish Clonal Hematopoiesis–Derived Variants in Liquid Biopsies from Patients with Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133610/
  26. www.sciencedirect.com www.sciencedirect.com
    Tissue tension fosters macrophage-driven lipid peroxidation-induced DNA damage
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    sciencedirect.com/science/article/pii/S1535610826001765
  27. Apr 2026
  28. aacrjournals.org aacrjournals.org
    Functional analysis of rare RAS variants of unknown significance
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    aacrjournals.org/cancerrescommun/article/5/10/1747/766027/Functional-Analysis-of-Rare-RAS-Variants-of
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    Patient-derived pediatric brain tumor orthotopic xenografts and tumor organoids faithfully recapitulate primary tumors
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    science.org/doi/10.1126/sciadv.aea4966
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mapping genomic heterogeneity in paediatric and adolescent-young adult sarcomas: insights from the Italian SAR-GEN2016 and SAR-GEN_ITA prospective multicenter trials
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    pmc.ncbi.nlm.nih.gov/articles/PMC13090861/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor genomics in patients younger than 40 years of age with metastatic breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13057355/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutational Signatures and Clonal Hematopoiesis in Intestinal Metaplasia across Countries with Varying Stomach Cancer Incidence
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    pmc.ncbi.nlm.nih.gov/articles/PMC13056296/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dynamic and Ongoing De Novo L1 Retrotransposition Contributes to Genome Plasticity and Intrapatient Heterogeneity in Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13055634/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integration of Short- and Long-Read RNA Sequencing Enables the Discovery of Circular RNAs
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    pmc.ncbi.nlm.nih.gov/articles/PMC12776659/
  35. 54.241.53.176 54.241.53.176
    Integrating interferon gamma receptor pathways, antigenicity, and immune contexture as predictors of immunotherapeutic strategies for mucosal melanomas
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    54.241.53.176/3e63435d4731406bfcdb4ffda4d231800522dc1e/inline-supplementary-material-1-html.html
  36. Mar 2026
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acquired High Tumor Mutational Burden and Activity of Immunotherapy after Targeted Therapy in Microsatellite Stable Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012239/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Phase 2 Trial of Niraparib in Patients with Advanced Pancreatic Cancer Harboring Pathogenic Variants in ATM, BRCA1, BRCA2, PALB2, and CHEK2
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    pmc.ncbi.nlm.nih.gov/articles/PMC13002239/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Germline predisposition to oncogenic alkylating damage in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12977196/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metastatic progression of pheochromocytoma and paraganglioma occurs via parallel evolution
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    pmc.ncbi.nlm.nih.gov/articles/PMC12963421/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatially Discontinuous Mutation Topographies in Ductal Carcinoma in Situ Reveal Non-Competitive Growth Dynamics
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    pmc.ncbi.nlm.nih.gov/articles/PMC12950944/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Precision Oncology for Pediatric Solid Tumors Using In‐Hospital Pediatric/AYA Malignancy‐Specific Panel Sequencing
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    pmc.ncbi.nlm.nih.gov/articles/PMC12951107/
  43. Feb 2026
  44. www.biorxiv.org www.biorxiv.org
    Systematic functional drug testing in patient-derived models reveals ex vivo sensitivities associated with clinical outcome in rare solid tumors
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    biorxiv.org/content/10.64898/2026.02.18.705724v1
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrating circulating tumor DNA analysis and radiomics for dynamic risk assessment in localized lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12324966/
  46. Jan 2026
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lazertinib with stereotactic body radiotherapy in oligometastatic EGFR-mutant non-small-cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12874586/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clinicogenomic characterization of inflammatory breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12255483/
  49. www.medrxiv.org www.medrxiv.org
    STK11 mutations and deletions define a distinct subtype of cervical adenocarcinoma
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    medrxiv.org/content/10.64898/2026.01.01.25343162v1
  50. www.nature.com www.nature.com
    Functional footprints of homologous recombination deficiency in prostate cancer revealed by ctDNA fragmentation and transcription factor accessibility
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    nature.com/articles/s41416-025-03301-0
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Assessment of Circulating Tumor DNA for Early Detection of Hepatocellular Carcinoma in Alpha‐Fetoprotein–Negative Patients With Cirrhotic Nodules
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    pmc.ncbi.nlm.nih.gov/articles/PMC12748524/
  52. Dec 2025
  53. www.nature.com www.nature.com
    Personalized ctDNA detection and genomic profiling in the NeoRHEA Study
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    nature.com/articles/s41523-025-00852-6
  54. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Extrachromosomal circular miRNA-gene amplifications contribute to the renal cancer phenotype
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    sciencedirect.com:5037/science/article/pii/S2211124725014329
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cancer Genomic Alterations and Microenvironmental Features Encode Synergistic Interactions with Disease Outcomes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12670080/
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Long-term Survival and Molecular Biomarker Evaluation of a Phase II Cetuximab and Nivolumab Clinical Trial in Recurrent/Metastatic Head and Neck Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12667737/
  57. Nov 2025
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DLBCL Cells Emerge after CD19 CAR T Cells with Cross-Antigen Resistance and a Gene Signature Predictive of Clinical CAR T-cell Response
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    pmc.ncbi.nlm.nih.gov/articles/PMC12591092/
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dynamics of Mutant Hematopoietic Progenitor Cells Are Not Associated with Clinical Outcomes in Multiple Myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12050965/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12569591/
  61. Oct 2025
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genomic and Immune Landscape of Pancreatic Ductal Adenocarcinoma Associated with Germline Pathogenic Variants in ATM
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    pmc.ncbi.nlm.nih.gov/articles/PMC12500237/
  63. Sep 2025
  64. www.sciencedirect.com www.sciencedirect.com
    Molecular basis of DNA recognition by the HMG-box-C1 module of capicua
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    sciencedirect.com/science/article/pii/S0969212625003223
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of Sorting Nexin 10 accelerates KRAS-induced pancreatic tumorigenesis
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    Phenotypic pleiotropy of missense variants in human B cell confinement receptor P2RY8
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    sciencedirect.com/science/article/pii/S2666979X2500237X
  67. aacrjournals.org aacrjournals.org
    Mutagenic Impact and Evolutionary Influence of Chemoradiotherapy in Hematologic Malignancies
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    aacrjournals.org/bloodcancerdiscov/article/6/5/450/764332/Mutagenic-Impact-and-Evolutionary-Influence-of
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    Detection of human brain cancers using genomic and immune cell characterization of cerebrospinal fluid through CSF-BAM
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    pmc.ncbi.nlm.nih.gov/articles/PMC12380150/
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cemiplimab in locally advanced or metastatic secondary angiosarcomas (CEMangio): A phase II clinical trial and biomarker analyses
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402795/
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Plasma exosomes from individuals with type 2 diabetes drive breast cancer aggression in patient-derived organoids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12381303/
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GPSai: A Clinically Validated AI Tool for Tissue of Origin Prediction During Routine Tumor Profiling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12399951/
  72. Jun 2025
  73. 52.53.155.43 52.53.155.43
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  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aged and BRCA-Mutated Stromal Cells Drive Epithelial Cell Transformation
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  76. May 2025
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inferring Drug–Gene Relationships in Cancer Using Literature-Augmented Large Language Models
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  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12046327/
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    Social, behavioral and clinical risk factors are associated with clonal hematopoiesis
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  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The genomic landscape of benign and malignant thyroid tumors from individuals carrying germline PTEN variants is distinct from sporadic thyroid cancers
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  81. Apr 2025
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    A Genomics-Driven Artificial Intelligence-Based Model Classifies Breast Invasive Lobular Carcinoma and Discovers CDH1 Inactivating Mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC11479818/
  84. www.sciencedirect.com www.sciencedirect.com
    Establishing a comprehensive panel of patient-derived xenograft models for high-grade endometrial carcinoma: molecular subtypes, genetic alterations, and therapeutic target profiling
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    sciencedirect.com/science/article/pii/S1476558625000375
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genomic Profiling to Contextualize the Results of Intervention for Smoldering Multiple Myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11444893/
  86. Mar 2025
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune Checkpoint Blockade Delays Cancer Development and Extends Survival in DNA Polymerase Mutator Syndromes
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    pmc.ncbi.nlm.nih.gov/articles/PMC11907192/
  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impact of Co-mutations and Transcriptional Signatures in Non–Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial
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    pmc.ncbi.nlm.nih.gov/articles/PMC11911804/
  89. Feb 2025
  90. www.sciencedirect.com www.sciencedirect.com
    Effect of MisMatch repair deficiency on metastasis occurrence in a syngeneic mouse model
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    sciencedirect.com/science/article/pii/S1476558625000247
  91. aacrjournals.org aacrjournals.org
    Multiomics Profiling Distinguishes Sebaceous Carcinoma from Benign Sebaceous Neoplasms and Provides Insight into the Genetic Evolution of Sebaceous Carcinogenesis
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    aacrjournals.org/clincancerres/article/30/21/4887/749133/Multiomics-Profiling-Distinguishes-Sebaceous
  92. www.cell.com www.cell.com
    Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy
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    cell.com/cell-stem-cell/fulltext/S1934-5909(25)00002-5
  93. Jan 2025
  94. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.17455
  95. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Predisposition footprints in the somatic genome of Wilms tumours
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617291/
  96. 52.53.155.43 52.53.155.43
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  97. Dec 2024
  98. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Exploiting NRF2-ARE pathway activation in papillary renal cell carcinoma
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35311
  99. www.mdpi.com www.mdpi.com
    Pan-Cancer Insights: A Study of Microbial Metabolite Receptors in Malignancy Dynamics
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    mdpi.com/2072-6694/16/24/4178
  100. Nov 2024
  101. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular and modular intricacies of precision oncology
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    pmc.ncbi.nlm.nih.gov/articles/PMC11537923/
  102. Oct 2024
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical value of liquid biopsy in FGFR2 fusion-positive cholangiocarcinoma patients during targeted therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443220/
  104. aacrjournals.org aacrjournals.org
    Clinical Outcome–Related Mutational Signatures Identified by Integrative Genomic Analysis in Nasopharyngeal Carcinoma
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    aacrjournals.org/clincancerres/article/26/24/6494/82920/Clinical-Outcome-Related-Mutational-Signatures
  105. Sep 2024
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural analysis of genomic and proteomic signatures reveal dynamic expression of intrinsically disordered regions in breast cancer
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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  117. May 2024
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  122. Mar 2024
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  127. Jan 2024
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  134. Jul 2023
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  136. Jun 2023
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  144. Feb 2023
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  147. Jan 2023
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  150. Dec 2022
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  159. Jun 2022
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  163. May 2022
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  167. Apr 2022
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  169. Dec 2021
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  171. Aug 2021
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  174. Jul 2021
  175. europepmc.org europepmc.org
    A homozygous FANCM mutation underlies a familial case of non-syndromic primary ovarian insufficiency.
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  176. Jun 2021
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  178. May 2021
  179. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Bladder tumor subtype commitment occurs in carcinoma in-situ driven by key signaling pathways including ECM remodeling
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    Comprehensive analysis of genomic alterations, clinical outcomes, putative functions and potential therapeutic value of MMP11 in human breast cancer
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  181. Apr 2021
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  183. Mar 2021
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    Germline EGFR variants are over-represented in adolescents and young adults (AYA) with adrenocortical carcinoma
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  186. Jan 2020
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    Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome
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    A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity
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  190. Nov 2018
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    Cell Model Passports—a hub for clinical, genetic and functional datasets of preclinical cancer models
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  192. Nov 2017
  193. elifesciences.org elifesciences.org
    A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC)
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    A network of epigenetic modifiers and DNA repair genes controls tissue-specific copy number alteration preference
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