210 Matching Annotations
  1. Aug 2025
  2. www.sciencedirect.com www.sciencedirect.com
    AI-driven multimodal algorithm predicts immunotherapy and targeted therapy outcomes in clear cell renal cell carcinoma
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    sciencedirect.com/science/article/pii/S2666379125003726
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70107
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A comparison of hepatitis B virus- and hepatitis C virus-related hepatocellular carcinoma: a bioinformatics analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12335692/
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    The urokinase receptor/uPAR is a major effector of p53 gain-of-function mutations in gemcitabine-treated pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S0021925825024123
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLC4A11 is a targetable marker correlated with therapeutic responses in ovarian cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12309138/
  7. Jul 2025
  8. 52.53.155.43 52.53.155.43
    MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD
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  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prognostic model of lung adenocarcinoma based on disulfidptosis-related genes and analysis of in vitro cell experiments for PPP1R14B in the model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12210501/
  10. Jun 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Itaconate and obesity-related hormones promote tumor progression – new insights on metabolic dysfunction in early-onset colon cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12183228/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nuclear Phase Separation Drives NPM1-mutant Acute Myeloid Leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12154763/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-Cell Transcriptomic Landscape Deciphers Intratumoral Heterogeneity and Subtypes of Acral and Mucosal Melanomas
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    pmc.ncbi.nlm.nih.gov/articles/PMC12163602/
  14. aacrjournals.org aacrjournals.org
    NLRP3 Inflammasome Activation Expands the Immunosuppressive Myeloid Stroma and Antagonizes the Therapeutic Benefit of STING Activation in Glioblastoma
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    aacrjournals.org/cancerrescommun/article/5/6/960/762951/NLRP3-Inflammasome-Activation-Expands-the
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  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combining Apatinib and Oxaliplatin Remodels the Immunosuppressive Tumor Microenvironment and Sensitizes Desert-Type Gastric Cancer to Immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12127801/
  19. May 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clear-Cell Renal Cell Carcinoma Molecular Subtypes Differ by African and European Genetic Similarity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12044083/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12046333/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TOP1 Mutations and Cross-Resistance to Antibody–Drug Conjugates in Patients with Metastatic Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12079096/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The genomic landscape of benign and malignant thyroid tumors from individuals carrying germline PTEN variants is distinct from sporadic thyroid cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11534558/
  24. www.sciencedirect.com www.sciencedirect.com
    MMRNet: Ensemble deep learning models for predicting mismatch repair deficiency in endometrial cancer from histopathological images
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    sciencedirect.com/science/article/pii/S2666379125001727
  25. Apr 2025
  26. aacrjournals.org aacrjournals.org
    Ancestral differences in anti-cancer treatment efficacy and their underlying genomic and molecular alterations
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    aacrjournals.org/cancerdiscovery/article/15/3/511/752115/Ancestral-Differences-in-Anticancer-Treatment
  27. www.sciencedirect.com www.sciencedirect.com
    Spatial mapping of gene signatures in H&E-stained images: a proof of concept for interpretable predictions using additive multiple instance learning
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    sciencedirect.com/science/article/pii/S0893395225000687
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Profiling the Activity of the Potent and Highly Selective CDK2 Inhibitor BLU-222 Reveals Determinants of Response in CCNE1-Aberrant Ovarian and Endometrial Tumors
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  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of a TNIK-CDK9 Axis as a Targetable Strategy for Platinum-Resistant Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962390/
  30. www.sciencedirect.com www.sciencedirect.com
    Oncogenic KRAS Addiction States Differentially Influence MTH1 Expression and 8-oxodGTPase Activity in Lung Adenocarcinoma
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    sciencedirect.com/science/article/pii/S2213231725001235
  31. Mar 2025
  32. www.sciencedirect.com www.sciencedirect.com
    GEF-H1 drives breast cancer cells to tumor progression
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    sciencedirect.com/science/article/pii/S0925443925001619
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    23ME-01473, an Fc Effector–Enhanced Anti-ULBP6/2/5 Antibody, Restores NK Cell–Mediated Antitumor Immunity through NKG2D and FcγRIIIa Activation
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  34. 52.53.155.43 52.53.155.43
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  35. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13820
  36. www.biorxiv.org www.biorxiv.org
    The carnosinase dipeptidase CNDP1 is a novel metabolic vulnerability in brain metastasis
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    biorxiv.org/content/10.1101/2025.03.18.644053v1
  37. Feb 2025
  38. 52.53.155.43 52.53.155.43
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    Co-evolution of atypical BRAF and KRAS mutations in colorectal tumorigenesis
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    Effect of MisMatch repair deficiency on metastasis occurrence in a syngeneic mouse model
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    sciencedirect.com/science/article/pii/S1476558625000247
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  42. aacrjournals.org aacrjournals.org
    Evaluating the Base Excision Repair Inhibitor TRC102 and Temozolomide for Patients with Recurrent Glioblastoma in the Phase 2 Adult Brain Tumor Consortium Trial BERT
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    aacrjournals.org/clincancerres/article/30/15/3167/746572/Evaluating-the-Base-Excision-Repair-Inhibitor
  43. aacrjournals.org aacrjournals.org
    Th17 cells secrete TWEAK to trigger epithelial-mesenchymal transition and promote colorectal cancer liver metastasis
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    aacrjournals.org/cancerres/article/84/8/1352/742976/Th17-Cells-Secrete-TWEAK-to-Trigger-Epithelial
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ternary Complex Components Responsible for Rapid LDL Internalization as Biomarkers for Breast Cancer Associated with Proliferation and Early Recurrence
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    pmc.ncbi.nlm.nih.gov/articles/PMC11791746/
  45. Jan 2025
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting PRMT1 Reduces Cancer Persistence and Tumor Relapse in EGFR- and KRAS-Mutant Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11747858/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RECQL4 affects MHC class II‐mediated signalling and favours an immune‐evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11734436/
  48. 52.53.155.43 52.53.155.43
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  50. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FGFR2-RUNX2 activation: An unexplored therapeutic pathway in luminal breast cancer related to tumor progression
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35302
  51. www.tandfonline.com www.tandfonline.com
    Resveratrol amplifies the anti-tumor effect of α-PD-1 by altering the intestinal microbiome and PGD2 content
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    tandfonline.com/doi/full/10.1080/19490976.2024.2447821
  52. Dec 2024
  53. www.mdpi.com www.mdpi.com
    Pan-Cancer Insights: A Study of Microbial Metabolite Receptors in Malignancy Dynamics
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    mdpi.com/2072-6694/16/24/4178
  54. www.science.org www.science.org
    Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer
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    science.org/doi/10.1126/scisignal.adp1375
  55. Nov 2024
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular and modular intricacies of precision oncology
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    pmc.ncbi.nlm.nih.gov/articles/PMC11537923/
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11532787/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glutamate Transport Proteins and Metabolic Enzymes are Poor Prognostic Factors in Invasive Lobular Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11507668/
  59. Sep 2024
  60. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    UA influences the progression of breast cancer via the AhR/p27Kip1/cyclin E pathway
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202400938R
  61. Aug 2024
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Predicting tumor mutation burden and VHL mutation from renal cancer pathology slides with self‐supervised deep learning
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    ncbi.nlm.nih.gov/pmc/articles/PMC11336896/
  63. Jul 2024
  64. www.sciencedirect.com www.sciencedirect.com
    Predictive Biomarkers for Response to TGF- β Inhibition in Resensitizing Chemo(radiated) Esophageal Adenocarcinoma
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin signaling mediates survival of dormant epithelial ovarian cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11257678/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11252164/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma
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  68. www.biorxiv.org www.biorxiv.org
    Genomic and single-cell characterization of patient-derived tumor organoid models of head and neck squamous cell carcinoma
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    biorxiv.org/content/10.1101/2024.06.28.601068v1
  69. Jun 2024
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early detection and diagnosis of cancer with interpretable machine learning to uncover cancer-specific DNA methylation patterns
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    ncbi.nlm.nih.gov/pmc/articles/PMC11186673/
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Surgical tumour resection deregulates Hallmarks of Cancer in resected tissue and the surrounding microenvironment
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    ncbi.nlm.nih.gov/pmc/articles/PMC11148542/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular Landscape and Clinical Implication of CCNE1-amplified Esophagogastric Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11146286/
  73. May 2024
  74. aacrjournals.org aacrjournals.org
    Bile acid metabolism mediates cholesterol homeostasis and promotes tumorigenesis in clear cell renal cell carcinoma
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  75. 52.53.155.43 52.53.155.43
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PPARα Agonism Enhances Immune Response to Radiotherapy while Dietary Oleic Acid Results in Counteraction
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    ncbi.nlm.nih.gov/pmc/articles/PMC11061609/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations
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    ncbi.nlm.nih.gov/pmc/articles/PMC11061612/
  78. Apr 2024
  79. aacrjournals.org aacrjournals.org
    Early-onset colon cancer shows a distinct intestinal microbiome and a host-microbe interaction
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    aacrjournals.org/cancerpreventionresearch/article/17/1/29/732148/Early-onset-Colon-Cancer-Shows-a-Distinct
  80. aacrjournals.org aacrjournals.org
    An NFAT1-C3a-C3aR Positive Feedback Loop in Tumor-Associated Macrophages Promotes a Glioma Stem Cell Malignant Phenotype
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    aacrjournals.org/cancerimmunolres/article/12/3/363/734680/An-NFAT1-C3a-C3aR-Positive-Feedback-Loop-in-Tumor
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11100297/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The immunomodulatory impact of naturally derived neem leaf glycoprotein on the initiation progression model of 4NQO induced murine oral carcinogenesis: a preclinical study
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    ncbi.nlm.nih.gov/pmc/articles/PMC10996442/
  83. Mar 2024
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MARCH2, a novel oncogene-regulated SNAIL E3 ligase, suppresses triple negative breast cancer metastases
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    ncbi.nlm.nih.gov/pmc/articles/PMC10977041/
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    D-2-HG Inhibits IDH1mut Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10959073/
  86. www.sciencedirect.com www.sciencedirect.com
    HIF-1α Mediates Immunosuppression and Chemoresistance in Colorectal Cancer by Inhibiting CXCL9, −10 and −11
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    sciencedirect.com/science/article/pii/S0753332224003111
  87. Feb 2024
  88. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
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    Cdc42-driven endosomal cholesterol transport promotes collateral resistance in HER2-positive gastric cancer
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    sciencedirect.com/science/article/pii/S0304383524000958
  90. www.nature.com www.nature.com
    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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    nature.com/articles/s41467-024-45067-8
  91. dx.doi.org dx.doi.org
    Active natural compounds perturb the melanoma risk-gene network
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    dx.doi.org/10.1093/g3journal/jkad274
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
  93. Jan 2024
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIB3, as a robust prognostic biomarker for HNSC, is associated with poor immune infiltration and cancer cell immune evasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10791810/
  95. www.sciencedirect.com www.sciencedirect.com
    Could the underlying biological basis of prognostic radiomics and deep learning signatures be explored in patients with lung cancer? A systematic review
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    sciencedirect.com/science/article/pii/S0720048X24000305
  96. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
  97. Dec 2023
  98. www.sciencedirect.com www.sciencedirect.com
    Cross-linking breast tumor transcriptomic states and tissue histology
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality
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    ncbi.nlm.nih.gov/pmc/articles/PMC10722143/
  100. Nov 2023
  101. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Establishing an early indicator for data sharing and reuse
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    onlinelibrary.wiley.com/doi/10.1002/leap.1586
  102. dx.doi.org dx.doi.org
    Population-specific Mutation Patterns in Breast Tumors from African American, European American, and Kenyan Patients
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  218. Feb 2021
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  220. Dec 2020
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  223. Oct 2020
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  226. Sep 2020
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  241. Jan 2020
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