273 Matching Annotations
  1. Jun 2024
  2. 52.53.155.43 52.53.155.43
    Developing potential drugs for insomnia through computational analysis
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    1. scibot 07 Jun 2024
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    2. scibot 07 Jun 2024
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    52.53.155.43/2a37f6c0c8921761dd7992d1615c1ce0ab7b8a25/bcde4332-2999-4e5c-b960-03e3c5ae7b03_135151_-_isaac_oronyi-html.html
  3. www.sciencedirect.com www.sciencedirect.com
    POT1 recruits and regulates CST-Polα/primase at human telomeres
    1
    1. scibot 05 Jun 2024
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      DOI: 10.1016/j.cell.2024.05.002

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    sciencedirect.com/science/article/pii/S0092867424004938
  4. Apr 2024
  5. 52.53.155.43 52.53.155.43
    Developing potential drugs for insomnia through computational analysis
    2
    1. scibot 23 Apr 2024
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      DOI: 10.12688/f1000research.135151.1

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    2. scibot 23 Apr 2024
      RRID:SCR_004097

      DOI: 10.12688/f1000research.135151.1

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    52.53.155.43/2a37f6c0c8921761dd7992d1615c1ce0ab7b8a25/bcde4332-2999-4e5c-b960-03e3c5ae7b03_135151_-_isaac_oronyi-html.html
  6. Mar 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural mechanisms for VMAT2 inhibition by tetrabenazine
    1
    1. scibot 27 Mar 2024
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      DOI: 10.7554/eLife.91973

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959523/
  8. www.sciencedirect.com www.sciencedirect.com
    ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat
    2
    1. scibot 15 Mar 2024
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      DOI: 10.1016/j.cell.2024.02.013

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    2. scibot 15 Mar 2024
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      DOI: 10.1016/j.cell.2024.02.013

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    sciencedirect.com/science/article/pii/S009286742400179X
  9. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM structures of the plant plastid-encoded RNA polymerase
    1
    1. scibot 01 Mar 2024
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      DOI: 10.1016/j.cell.2024.01.026

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    sciencedirect.com/science/article/pii/S0092867424000631
  10. Feb 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113845

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    sciencedirect.com/science/article/pii/S2211124724001736
  12. Jan 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Evolution of Polyclonal Antibody from Specific Epitope 47kDA for Detection of Bladder Cancer
    1
    1. scibot 05 Jan 2024
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      DOI: 10.31557/APJCP.2023.24.9.3155

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    ncbi.nlm.nih.gov/pmc/articles/PMC10762744/
  14. Dec 2023
  15. www.sciencedirect.com www.sciencedirect.com
    Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy
    1
    1. scibot 20 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113490

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    sciencedirect.com/science/article/pii/S2211124723015024
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    Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense
    1
    1. scibot 16 Dec 2023
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      DOI: 10.1016/j.molcel.2023.11.007

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    sciencedirect.com/science/article/pii/S1097276523009498
  17. Nov 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Evolutionary diversification reveals distinct somatic versus germline cytoskeletal functions of the Arp2 branched actin nucleator protein
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.cub.2023.10.055

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    sciencedirect.com/science/article/pii/S0960982223014562
  19. www.sciencedirect.com www.sciencedirect.com
    Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase
    1
    1. scibot 18 Nov 2023
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      DOI: 10.1016/j.immuni.2023.10.005

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    sciencedirect.com/science/article/pii/S1074761323004454
  20. www.sciencedirect.com www.sciencedirect.com
    Architecture of the bacteriophage lambda tail
    1
    1. scibot 03 Nov 2023
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      DOI: 10.1016/j.str.2023.10.006

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    sciencedirect.com/science/article/pii/S0969212623003635
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Energy coupling and stoichiometry of Zn2+/H+ antiport by the prokaryotic cation diffusion facilitator YiiP
    1
    1. scibot 02 Nov 2023
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      DOI: 10.7554/eLife.87167

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    ncbi.nlm.nih.gov/pmc/articles/PMC10617992/
  22. Oct 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.molcel.2023.09.037

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    sciencedirect.com/science/article/pii/S1097276523008031
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evolution and functional role prediction of the CYP6DE and CYP6DJ subfamilies in Dendroctonus (Curculionidae: Scolytinae) bark beetles
    1
    1. scibot 27 Oct 2023
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      DOI: 10.3389/fmolb.2023.1274838

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    ncbi.nlm.nih.gov/pmc/articles/PMC10593416/
  25. 52.53.155.43 52.53.155.43
    Developing potential drugs for insomnia through computational analysis
    1
    1. scibot 22 Oct 2023
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      DOI: 10.12688/f1000research.135151.1

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    52.53.155.43/2a37f6c0c8921761dd7992d1615c1ce0ab7b8a25/bcde4332-2999-4e5c-b960-03e3c5ae7b03_135151_-_isaac_oronyi-html.html
  26. 52.53.155.43 52.53.155.43
    Germline-targeting chimpanzee SIV Envelopes induce V2-apex broadly neutralizing-like B cell precursors in a rhesus macaque infection model
    1
    1. scibot 20 Oct 2023
      SCR_004097

      DOI: 10.1101/2023.09.21.558743

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    52.53.155.43/baafb843c69b6e0b8e00b84146cf1a1c4ee086dd/2023.09.21.558743v1.full-html.html
  27. www.nature.com www.nature.com
    A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response
    2
    1. scibot 20 Oct 2023
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      DOI: 10.1038/s41556-023-01248-z

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    2. scibot 20 Oct 2023
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      DOI: 10.1038/s41556-023-01248-z

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    nature.com/articles/s41556-023-01248-z
  28. Sep 2023
  29. link.springer.com link.springer.com
    Antiviral mechanisms of sorafenib against foot-and-mouth disease virus via c-RAF and AKT/PI3K pathways
    1
    1. scibot 14 Sep 2023
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      DOI: 10.1007/s11259-023-10211-0

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    link.springer.com/article/10.1007/s11259-023-10211-0
  30. Jul 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Discovery of a glutathione utilization pathway in Francisella that shows functional divergence between environmental and pathogenic species
    1
    1. scibot 15 Jul 2023
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      DOI: 10.1016/j.chom.2023.06.010

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    sciencedirect.com/science/article/pii/S1931312823002615
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor
    1
    1. scibot 14 Jul 2023
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      DOI: 10.7554/eLife.86029

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    ncbi.nlm.nih.gov/pmc/articles/PMC10338036/
  33. Jun 2023
  34. f1000research.com f1000research.com
    <i>In silico</i> screening for potential inhibitors from the phytocompounds of <i>Carica papaya</i> against Zika virus NS5 protein
    1
    1. scibot 24 Jun 2023
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      DOI: 10.12688/f1000research.134956.1

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    f1000research.com/articles/12-655
  35. f1000research.com f1000research.com
    F1000Research Article: Pharmacokinetic and pharmacodynamic profiling of compounds similar to paracetamol from zinc database: an <i>in silico</i> analysis.
    1
    1. scibot 24 Jun 2023
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      DOI: 10.12688/f1000research.133839.1

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    f1000research.com/articles/12-720
  36. www.sciencedirect.com www.sciencedirect.com
    Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.molcel.2023.05.036

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    sciencedirect.com/science/article/pii/S1097276523004203
  37. 52.53.155.43 52.53.155.43
    Virtual screening of zinc compounds similar to NSAIDS with better pharmacodynamic and pharmacokinetic profiles
    1
    1. scibot 10 Jun 2023
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      DOI: 10.12688/f1000research.132017.1

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    52.53.155.43/40ed8239170cda29dbd144f77a8cf91c57b6812a/6491c0f7-d84e-4e28-be5f-1dd7107d3463_132017_-_faith_kamakia-html.html
  38. May 2023
  39. www.sciencedirect.com www.sciencedirect.com
    A novel IRE1 kinase inhibitor for adjuvant glioblastoma treatment.
    1
    1. scibot 06 May 2023
      RRID:SCR_004097

      DOI: 10.1016/j.isci.2023.106687

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    sciencedirect.com/science/article/pii/S2589004223007642
  40. Apr 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural and functional properties of a plant NRAMP-related aluminum transporter
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    1. scibot 27 Apr 2023
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      DOI: 10.7554/eLife.85641

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    ncbi.nlm.nih.gov/pmc/articles/PMC10115441/
  42. www.sciencedirect.com www.sciencedirect.com
    Systematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypes
    2
    1. scibot 08 Apr 2023
      RRID:SCR_004097

      DOI: 10.1016/j.celrep.2023.112370

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    2. scibot 08 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112370

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    sciencedirect.com/science/article/pii/S2211124723003819
  43. Mar 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster
    1
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      DOI: 10.7554/eLife.84424

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    ncbi.nlm.nih.gov/pmc/articles/PMC9977279/
  45. f1000research.com f1000research.com
    F1000Research Article: In silico molecular docking and molecular dynamic simulation of agarwood compounds with molecular targets of Alzheimer’s disease .
    1
    1. scibot 04 Mar 2023
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      DOI: 10.12688/f1000research.130618.1

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    f1000research.com/articles/12-230
  46. Feb 2023
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation
    1
    1. scibot 17 Feb 2023
      RRID:SCR_004097

      DOI: 10.1126/sciadv.adg2997

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    ncbi.nlm.nih.gov/pmc/articles/PMC9931213/
  48. www.sciencedirect.com www.sciencedirect.com
    Structural basis of a transcription pre-initiation complex on a divergent promoter
    1
    1. scibot 04 Feb 2023
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      DOI: 10.1016/j.molcel.2023.01.011

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    sciencedirect.com/science/article/pii/S109727652300031X
  49. www.sciencedirect.com www.sciencedirect.com
    Spermine enhances antiviral and anticancer responses by stabilizing DNA binding with the DNA sensor cGAS
    1
    1. scibot 02 Feb 2023
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      DOI: 10.1016/j.immuni.2023.01.001

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    sciencedirect.com/science/article/pii/S1074761323000110
  50. Jan 2023
  51. www.sciencedirect.com www.sciencedirect.com
    Nucleosome dyad determines the H1 C-terminus collapse on distinct DNA arms
    1
    1. scibot 07 Jan 2023
      RRID:SCR_004097

      DOI: 10.1016/j.str.2022.12.005

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    sciencedirect.com/science/article/pii/S0969212622004919
  52. www.sciencedirect.com www.sciencedirect.com
    The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions
    1
    1. scibot 02 Jan 2023
      RRID:SCR_004097

      DOI: 10.1016/j.celrep.2022.111902

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    sciencedirect.com/science/article/pii/S2211124722018010
  53. Dec 2022
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Changes in seam number and location induce holes within microtubules assembled from porcine brain tubulin and in Xenopus egg cytoplasmic extracts
    1
    1. scibot 31 Dec 2022
      RRID:SCR_004097

      DOI: 10.7554/eLife.83021

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  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of human phagocyte NADPH oxidase in the resting state
    1
    1. scibot 02 Dec 2022
      RRID:SCR_004097

      DOI: 10.7554/eLife.83743

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    ncbi.nlm.nih.gov/pmc/articles/PMC9711523/
  56. Nov 2022
  57. www.sciencedirect.com www.sciencedirect.com
    Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes
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      DOI: 10.1016/j.cell.2022.10.030

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    sciencedirect.com/science/article/pii/S0092867422013769
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes
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      DOI: 10.1016/j.immuni.2022.10.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC9606073/
  59. Oct 2022
  60. elifesciences.org elifesciences.org
    A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation
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      DOI: 10.7554/eLife.79771

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    elifesciences.org/articles/79771
  61. www.sciencedirect.com www.sciencedirect.com
    A step-by-step protocol for capturing conformational snapshots of ligand gated ion channels by single-particle cryo-EM
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    sciencedirect.com/science/article/pii/S2666166722006128
  62. Aug 2022
  63. www.sciencedirect.com www.sciencedirect.com
    TITLE: Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways
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      DOI: 10.1016/j.isci.2022.104914

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    sciencedirect.com/science/article/pii/S2589004222011865
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanism of the cadherin–catenin F-actin catch bond interaction
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      DOI: 10.7554/eLife.80130

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    ncbi.nlm.nih.gov/pmc/articles/PMC9402232/
  65. www.sciencedirect.com www.sciencedirect.com
    Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC
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      DOI: 10.1016/j.cell.2022.07.010

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    sciencedirect.com/science/article/pii/S0092867422009138
  66. Jul 2022
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ architecture of the lipid transport protein VPS13C at ER–lysosome membrane contacts
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      DOI: 10.1073/pnas.2203769119

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    ncbi.nlm.nih.gov/pmc/articles/PMC9303930/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conserved structural elements specialize ATAD1 as a membrane protein extraction machine
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      DOI: 10.7554/eLife.73941

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    ncbi.nlm.nih.gov/pmc/articles/PMC9273213/
  69. Jun 2022
  70. journals.plos.org journals.plos.org
    Inhibition of histone H3-H4 chaperone pathways rescues C. elegans sterility by H2B loss
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      DOI: 10.1371/journal.pgen.1010223

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  71. www.sciencedirect.com www.sciencedirect.com
    Rational exploration of fold atlas for human solute carrier proteins
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      DOI: 10.1016/j.str.2022.05.015

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    sciencedirect.com/science/article/pii/S0969212622001897
  72. Apr 2022
  73. www.sciencedirect.com www.sciencedirect.com
    RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex
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      DOI: 10.1016/j.celrep.2022.110732

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    sciencedirect.com/science/article/pii/S2211124722004934
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis Of Memory B Cells Identifies Conserved Neutralizing Epitopes On The N-Terminal Domain Of Variant SARS-Cov-2 Spike Proteins
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      DOI: 10.1016/j.immuni.2022.04.003

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    ncbi.nlm.nih.gov/pmc/articles/PMC8986478/
  75. www.sciencedirect.com www.sciencedirect.com
    Dynamic immunodominance hierarchy of neutralizing antibody responses to evolving GII.4 noroviruses
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      DOI: 10.1016/j.celrep.2022.110689

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    sciencedirect.com/science/article/pii/S2211124722004478
  76. Mar 2022
  77. www.sciencedirect.com www.sciencedirect.com
    Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses
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      DOI: 10.1016/j.cell.2022.02.023

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    sciencedirect.com/science/article/pii/S0092867422002033
  78. www.sciencedirect.com www.sciencedirect.com
    Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB
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      DOI: 10.1016/j.str.2022.02.007

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    sciencedirect.com/science/article/pii/S0969212622000430
  79. www.sciencedirect.com www.sciencedirect.com
    Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance
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      RRID:SCR_004097

      DOI: 10.1016/j.molcel.2022.01.028

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    sciencedirect.com/science/article/pii/S1097276522001046
  80. www.sciencedirect.com www.sciencedirect.com
    Structure-guided changes at the V2 apex of HIV-1 clade C trimer enhance elicitation of autologous neutralizing and broad V1V2-scaffold antibodies
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      DOI: 10.1016/j.celrep.2022.110436

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    sciencedirect.com/science/article/pii/S2211124722001632
  81. Feb 2022
  82. www.sciencedirect.com www.sciencedirect.com
    Gene architecture directs splicing outcome in separate nuclear spatial regions
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      RRID:SCR_004097

      DOI: 10.1016/j.molcel.2022.02.001

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    sciencedirect.com/science/article/pii/S109727652200106X
  83. elifesciences.org elifesciences.org
    Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats
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      DOI: 10.7554/eLife.72908

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    elifesciences.org/articles/72908
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection
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      DOI: 10.1016/j.celrep.2022.110368

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    ncbi.nlm.nih.gov/pmc/articles/PMC8786652/
  85. elifesciences.org elifesciences.org
    Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family
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      DOI: 10.7554/eLife.74589

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    elifesciences.org/articles/74589
  86. Jan 2022
  87. www.sciencedirect.com www.sciencedirect.com
    Structural basis of bacteriophage lambda capsid maturation
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      DOI: 10.1016/j.str.2021.12.009

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    sciencedirect.com/science/article/pii/S0969212621004615
  88. www.sciencedirect.com www.sciencedirect.com
    Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II
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      DOI: 10.1016/j.molcel.2021.12.020

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    sciencedirect.com/science/article/pii/S1097276521010820
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern
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      DOI: 10.1016/j.celrep.2021.110210

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    ncbi.nlm.nih.gov/pmc/articles/PMC8673750/
  90. Dec 2021
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tracking the movement of discrete gating charges in a voltage-gated potassium channel
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      DOI: 10.7554/eLife.58148

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    ncbi.nlm.nih.gov/pmc/articles/PMC8635975/
  92. Nov 2021
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A single aromatic residue in sgp130Fc (olamkicept) allows the discrimination between interleukin-6 (IL-6) and IL-11 trans-signaling
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      DOI: 10.1016/j.isci.2021.103309

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    ncbi.nlm.nih.gov/pmc/articles/PMC8571719/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ITEM-THREE analysis of a monoclonal anti-malaria antibody reveals its assembled epitope on the pfMSP119 antigen
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      DOI: 10.1074/jbc.RA120.014802

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    ncbi.nlm.nih.gov/pmc/articles/PMC7606685/
  95. www.sciencedirect.com www.sciencedirect.com
    Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1
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    sciencedirect.com/science/article/pii/S0969212621003725
  96. Oct 2021
  97. www.sciencedirect.com www.sciencedirect.com
    Pan-ebolavirus protective therapy by two multifunctional human antibodies
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    1. scibot 29 Oct 2021
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      DOI: 10.1016/j.cell.2021.09.035

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    sciencedirect.com/science/article/pii/S009286742101165X
  98. www.sciencedirect.com www.sciencedirect.com
    Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells
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      DOI: 10.1016/j.celrep.2021.109877

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    sciencedirect.com/science/article/pii/S2211124721013474
  99. www.sciencedirect.com www.sciencedirect.com
    Identification of docosahexaenoic and eicosapentaenoic acids multiple targets facing periodontopathogens
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      DOI: 10.1016/j.micpath.2021.105266

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    sciencedirect.com/science/article/pii/S0882401021005404
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cheonggukjang-Specific Component 1,3-Diphenyl-2-Propanone as a Novel PPARα/γ Dual Agonist: An In Vitro and In Silico Study
    1
    1. scibot 15 Oct 2021
      RRID:SCR_004097

      DOI: 10.3390/ijms221910884

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    ncbi.nlm.nih.gov/pmc/articles/PMC8509681/
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural insights into the activation of human calcium-sensing receptor
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      DOI: 10.7554/eLife.68578

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    ncbi.nlm.nih.gov/pmc/articles/PMC8476121/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells
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      DOI: 10.7554/eLife.71474

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    ncbi.nlm.nih.gov/pmc/articles/PMC8480983/
  103. Sep 2021
  104. www.sciencedirect.com www.sciencedirect.com
    Structural basis and regulation of the reductive stress response
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      DOI: 10.1016/j.cell.2021.09.002

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    sciencedirect.com/science/article/pii/S0092867421010497
  105. www.sciencedirect.com www.sciencedirect.com
    Live Imaging of SARS-CoV-2 Infection in Mice Reveals that Neutralizing Antibodies Require Fc Function for Optimal Efficacy
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      DOI: 10.1016/j.immuni.2021.08.015

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    sciencedirect.com/science/article/pii/S1074761321003472
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies
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      DOI: 10.1016/j.celrep.2021.109760

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    ncbi.nlm.nih.gov/pmc/articles/PMC8423902/
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace
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      DOI: 10.7554/eLife.68799

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    ncbi.nlm.nih.gov/pmc/articles/PMC8439657/
  108. www.sciencedirect.com www.sciencedirect.com
    Negative charge in the RACK1 loop broadens the translational capacity of the human ribosome
    1
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      DOI: 10.1016/j.celrep.2021.109663

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  109. www.sciencedirect.com www.sciencedirect.com
    Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
    1
    1. scibot 08 Sep 2021
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      DOI: 10.1016/j.cell.2021.08.012

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    Cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein
    1
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      DOI: 10.1016/j.celrep.2021.109628

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  111. www.sciencedirect.com www.sciencedirect.com
    High-resolution structure of the membrane-embedded skeletal muscle ryanodine receptor
    1
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  112. Aug 2021
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase
    1
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  114. elifesciences.org elifesciences.org
    Functional development of a V3/glycan-specific broadly neutralizing antibody isolated from a case of HIV superinfection
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      DOI: 10.7554/eLife.68110

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  115. www.sciencedirect.com www.sciencedirect.com
    Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals
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  116. link.springer.com link.springer.com
    An Insilico evaluation of phytocompounds from Albizia amara and Phyla nodiflora as cyclooxygenase-2 enzyme inhibitors
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    1. scibot 21 Aug 2021
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      DOI: 10.1007/s40199-021-00408-6

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  117. www.cell.com www.cell.com
    (p)ppGpp controls stringent factors by exploiting antagonistic allosteric coupling between catalytic domains
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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural heterogeneity of cellular K5/K14 filaments as revealed by cryo-electron microscopy
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      DOI: 10.7554/eLife.70307

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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation
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  120. elifesciences.org elifesciences.org
    A Cryptochrome 2 mutation yields advanced sleep phase in humans
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  121. elifesciences.org elifesciences.org
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  123. elifesciences.org elifesciences.org
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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core
    1
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  127. elifesciences.org elifesciences.org
    Structure and analysis of nanobody binding to the human ASIC1a ion channel
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  128. elifesciences.org elifesciences.org
    Cryo-EM structures of the caspase-activated protein XKR9 involved in apoptotic lipid scrambling
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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase
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  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of translationally inactive mammalian ribosomes
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  131. elifesciences.org elifesciences.org
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  132. www.frontiersin.org www.frontiersin.org
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  133. Jul 2021
  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms
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  135. elifesciences.org elifesciences.org
    A contractile injection system stimulates tubeworm metamorphosis by translocating a proteinaceous effector
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  136. www.nature.com www.nature.com
    Structure of the thermo-sensitive TRP channel TRP1 from the alga Chlamydomonas reinhardtii
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      DOI: 10.1038/s41467-019-12121-9

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  137. www.nature.com www.nature.com
    ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12–ATG5-ATG16L1 complex assembly and autophagy
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      DOI: 10.1038/s41421-019-0110-1

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  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes
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  139. elifesciences.org elifesciences.org
    Mechanism of pharmacochaperoning in a mammalian KATP channel revealed by cryo-EM
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      DOI: 10.7554/eLife.46417

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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism
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  141. www.sciencedirect.com www.sciencedirect.com
    Microtubule Tip Tracking by the Spindle and Kinetochore Protein Ska1 Requires Diverse Tubulin-Interacting Surfaces
    1
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      DOI: 10.1016/j.cub.2017.10.018

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  142. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A photoswitchable GABA receptor channel blocker
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      DOI: 10.1111/bph.14689

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14689
  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of translationally inactive mammalian ribosomes
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  144. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Domain structure of HelD, an interaction partner of Bacillus subtilis RNA polymerase
    1
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      DOI: 10.1002/1873-3468.13385

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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.13385
  145. www.frontiersin.org www.frontiersin.org
    Accumulation of Dense Core Vesicles in Hippocampal Synapses Following Chronic Inactivity
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      DOI: 10.3389/fnana.2018.00048

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  146. www.sciencedirect.com www.sciencedirect.com
    Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex
    2
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      SCR_004097

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      DOI: 10.1016/j.cell.2016.08.050

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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A fusion peptide in preS1 and the human protein disulfide isomerase ERp57 are involved in hepatitis B virus membrane fusion process
    1
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  148. Jun 2021
  149. www.sciencedirect.com www.sciencedirect.com
    B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV
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      DOI: 10.1016/j.cell.2021.04.032

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  150. May 2021
  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Design principles of the ESCRT-III Vps24-Vps2 module
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      DOI: 10.7554/eLife.67709

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  152. www.sciencedirect.com www.sciencedirect.com
    Mining HIV controllers for broad and functional antibodies to recognize and eliminate HIV-infected cells
    1
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      DOI: 10.1016/j.celrep.2021.109167

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    sciencedirect.com/science/article/pii/S221112472100509X
  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural Insights of Shigella Translocator IpaB and Its Chaperone IpgC in Solution
    1
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      DOI: 10.3389/fcimb.2021.673122

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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CM1-driven assembly and activation of yeast γ-tubulin small complex underlies microtubule nucleation
    1
    1. scibot 12 May 2021
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      DOI: 10.7554/eLife.65168

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  155. www.sciencedirect.com www.sciencedirect.com
    The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain
    1
    1. scibot 09 May 2021
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      DOI: 10.1016/j.str.2020.06.008

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    sciencedirect.com/science/article/pii/S0969212620302112
  156. www.sciencedirect.com www.sciencedirect.com
    Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP
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  157. www.sciencedirect.com www.sciencedirect.com
    Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization
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    sciencedirect.com/science/article/pii/S109727652030349X
  158. Apr 2021
  159. www.sciencedirect.com www.sciencedirect.com
    Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1
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  160. www.sciencedirect.com www.sciencedirect.com
    Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex
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  161. www.sciencedirect.com www.sciencedirect.com
    Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form
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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dental workers in front-line of COVID-19: an in silico evaluation targeting their prevention
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  163. elifesciences.org elifesciences.org
    Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor
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  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinetic analysis of ASIC1a delineates conformational signaling from proton-sensing domains to the channel gate
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  165. Mar 2021
  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein
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      DOI: 10.1016/j.cell.2021.03.029

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  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure and immune recognition of the porcine epidemic diarrhea virus spike protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC7962898/
  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alternative splicing of clathrin heavy chain contributes to the switch from coated pits to plaques
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      DOI: 10.1083/jcb.201912061

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    ncbi.nlm.nih.gov/pmc/articles/PMC7480091/
  169. www.sciencedirect.com www.sciencedirect.com
    Structural basis for self-cleavage prevention by tag:anti-tag pairing complementarity in type VI Cas13 CRISPR systems
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    sciencedirect.com/science/article/pii/S1097276520309540
  170. Feb 2021
  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atomic structure of a mitochondrial complex I intermediate from vascular plants
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    ncbi.nlm.nih.gov/pmc/articles/PMC7447434/
  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures reveal gatekeeping of the mitochondrial Ca2+ uniporter by MICU1-MICU2
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      DOI: 10.7554/eLife.59991

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  173. elifesciences.org elifesciences.org
    A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery
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      DOI: 10.7554/eLife.52158

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    elifesciences.org/articles/52158
  174. www.cell.com www.cell.com
    Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody
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      DOI: 10.1016/j.cell.2020.01.010

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    cell.com/cell/abstract/S0092-8674(20)30057-X
  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy
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      DOI: 10.7554/eLife.48907

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    ncbi.nlm.nih.gov/pmc/articles/PMC6957273/
  176. www.sciencedirect.com www.sciencedirect.com
    The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction
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      DOI: 10.1016/j.celrep.2021.108753

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    sciencedirect.com/science/article/pii/S2211124721000668
  177. www.sciencedirect.com www.sciencedirect.com
    Cone-shaped HIV-1 capsids are transported through intact nuclear pores
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      DOI: 10.1016/j.cell.2021.01.025

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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Magnesium efflux from Drosophila Kenyon cells is critical for normal and diet-enhanced long-term memory
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      DOI: 10.7554/eLife.61339

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    ncbi.nlm.nih.gov/pmc/articles/PMC7843133/
  179. www.sciencedirect.com www.sciencedirect.com
    Mimicry of Canonical Translation Elongation Underlies Alanine Tail Synthesis in RQC
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  180. Jan 2021
  181. elifesciences.org elifesciences.org
    Atomic structures of respiratory complex III 2, complex IV, and supercomplex III 2-IV from vascular plants
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      DOI: 10.7554/eLife.62047

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  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of bacterial phospholipid transporter MlaFEDB with substrate bound
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      DOI: 10.7554/eLife.62518

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    ncbi.nlm.nih.gov/pmc/articles/PMC7790496/
  183. Dec 2020
  184. www.sciencedirect.com www.sciencedirect.com
    Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts
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      DOI: 10.1016/j.celrep.2020.108534

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    sciencedirect.com/science/article/pii/S2211124720315230
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    The Halastavi árva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism
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      DOI: 10.1016/j.celrep.2020.108476

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    sciencedirect.com/science/article/pii/S2211124720314650
  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation
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      DOI: 10.7554/eLife.62772

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    ncbi.nlm.nih.gov/pmc/articles/PMC7723414/
  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11
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      DOI: 10.7554/eLife.59018

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    ncbi.nlm.nih.gov/pmc/articles/PMC7704109/
  188. elifesciences.org elifesciences.org
    The structures of secretory and dimeric immunoglobulin A
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      DOI: 10.7554/eLife.56098

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    elifesciences.org/articles/56098
  189. www.sciencedirect.com www.sciencedirect.com
    Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition
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      DOI: 10.1016/j.chom.2020.11.007

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    sciencedirect.com/science/article/pii/S1931312820306247
  190. www.sciencedirect.com www.sciencedirect.com
    A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide
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      DOI: 10.1016/j.celrep.2020.108428

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    sciencedirect.com/science/article/pii/S2211124720314170
  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large domain movements through the lipid bilayer mediate substrate release and inhibition of glutamate transporters
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      DOI: 10.7554/eLife.58417

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    ncbi.nlm.nih.gov/pmc/articles/PMC7682989/
  192. Nov 2020
  193. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles
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      DOI: 10.1016/j.chom.2020.11.001

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    pubmed.ncbi.nlm.nih.gov/33242391/
  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates
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      DOI: 10.7554/eLife.61496

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    ncbi.nlm.nih.gov/pmc/articles/PMC7652416/
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of αE-catenin–F-actin catch bond behavior
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      DOI: 10.7554/eLife.60878

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    ncbi.nlm.nih.gov/pmc/articles/PMC7588230/
  196. Oct 2020
  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular mechanism for direct actin force-sensing by α-catenin
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      DOI: 10.7554/eLife.62514

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    ncbi.nlm.nih.gov/pmc/articles/PMC7588232/
  198. www.sciencedirect.com www.sciencedirect.com
    Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses
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      DOI: 10.1016/j.immuni.2020.10.005

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    sciencedirect.com/science/article/pii/S1074761320304465
  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch
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      DOI: 10.7554/eLife.61991

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    ncbi.nlm.nih.gov/pmc/articles/PMC7577740/
  200. Sep 2020
  201. www.sciencedirect.com www.sciencedirect.com
    HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies
    1
    1. scibot 25 Sep 2020
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      DOI: 10.1016/j.celrep.2020.107583

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  202. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An ER translocon for multi-pass membrane protein biogenesis
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    1. scibot 25 Sep 2020
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      DOI: 10.7554/eLife.56889

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    ncbi.nlm.nih.gov/pmc/articles/PMC7505659/
  203. elifesciences.org elifesciences.org
    Structural insights into the Ca2+-dependent gating of the human mitochondrial calcium uniporter
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    1. scibot 23 Sep 2020
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      DOI: 10.7554/eLife.60513

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  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of substrate recognition by a polypeptide processing and secretion transporter
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  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural insights and activating mutations in diverse pathologies define mechanisms of deregulation for phospholipase C gamma enzymes
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  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gating and selectivity mechanisms for the lysosomal K+ channel TMEM175
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  207. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs
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  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structures of S-OPA1 reveal its interactions with membrane and changes upon nucleotide binding
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  209. elifesciences.org elifesciences.org
    Cryo-EM structure of the lysosomal chloride-proton exchanger CLC-7 in complex with OSTM1
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  210. elifesciences.org elifesciences.org
    Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5
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    Molecular principles of assembly, activation, and inhibition in epithelial sodium channel
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  212. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM Reveals Integrin-Mediated TGF-β Activation without Release from Latent TGF-β
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  213. elifesciences.org elifesciences.org
    Structure of RNA polymerase bound to ribosomal 30S subunit
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  214. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemical and structural investigation of the paroxetine-human serotonin transporter complex
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  215. www.cell.com www.cell.com
    Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody
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  216. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism
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  217. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate
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  218. elifesciences.org elifesciences.org
    Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations
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  219. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C-mannosylation supports folding and enhances stability of thrombospondin repeats
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  220. elifesciences.org elifesciences.org
    Structure and activation mechanism of the BBSome membrane protein trafficking complex
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    Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization
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  222. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structure of VASH1-SVBP bound to microtubules
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  223. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β11-12 linker isomerization governs acid-sensing ion channel desensitization and recovery
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  224. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alternative splicing of coq-2 controls the levels of rhodoquinone in animals
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  225. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies
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  226. elifesciences.org elifesciences.org
    Molecular determinants of large cargo transport into the nucleus
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    The His-Gly motif of acid-sensing ion channels resides in a reentrant ‘loop’ implicated in gating and ion selectivity
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    Mitochondrial ClpX activates an essential biosynthetic enzyme through partial unfolding
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    Atomic structure of a mitochondrial complex I intermediate from vascular plants
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  230. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures reveal gatekeeping of the mitochondrial Ca2+ uniporter by MICU1-MICU2
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  231. elifesciences.org elifesciences.org
    Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction
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      DOI: 10.7554/eLife.54031

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  232. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limited dishevelled/Axin oligomerization determines efficiency of Wnt/β-catenin signal transduction
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  233. Jan 2020
  234. www.sciencedirect.com www.sciencedirect.com
    Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies
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      DOI: 10.1016/j.chom.2019.10.002

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  235. elifesciences.org elifesciences.org
    Self-capping of nucleoprotein filaments protects Newcastle Disease Virus genome
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      DOI: 10.7554/eLife.45057

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  236. www.sciencedirect.com www.sciencedirect.com
    Characterization of Fully Recombinant Human 20S and 20S-PA200 Proteasome Complexes
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      DOI: 10.1016/j.molcel.2019.07.014

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  237. elifesciences.org elifesciences.org
    Regulation of Eag1 gating by its intracellular domains
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      DOI: 10.7554/eLife.49188

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