187 Matching Annotations
  1. Last 7 days
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    Loss of BPTF restores estrogen response and suppresses metastasis of mammary tumors
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    nature.com/articles/s41467-025-64255-8
  3. Oct 2025
  4. www.biorxiv.org www.biorxiv.org
    ACSS2-Mediated Metabolic-Epigenetic Crosstalk Drives Fulvestrant Resistance and Represents a Novel Therapeutic Target
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    biorxiv.org/content/10.1101/2025.09.23.678089v1
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrative Genotyping and Analysis of Canine Structural Variation Using Long-read and Short-read Data
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    pmc.ncbi.nlm.nih.gov/articles/PMC12481690/
  6. Sep 2025
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    IGF2BP3 redirects glycolytic flux to promote one-carbon metabolism and RNA methylation
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    sciencedirect.com/science/article/pii/S2211124725011015
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    Human papillomavirus integration induces oncogenic host gene fusions in oropharyngeal cancers
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    aacrjournals.org/cancerdiscovery/article/15/9/1927/764362/Human-Papillomavirus-Integration-Induces-Oncogenic
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    Elevated Transglutaminase-2 in SOX10-Deficient Melanoma Promotes Tumor Onset and Decreases Intratumoral CD4+ T Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12398951/
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    Regulatory Role for Tumor Suppressor REST on Estrogen Receptor (ESR1) Expression and Leiomyoma Pathophysiology
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    biorxiv.org/content/10.1101/2025.08.29.673140v1
  11. Jul 2025
  12. 52.53.155.43 52.53.155.43
    bilinovich-et-al-2025-methyl-cpg-binding-domain-as-a-protein-interaction-partner-in-promoter-regulation-and-html.html
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    Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer
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    sciencedirect.com/science/article/pii/S1074761325002742
  14. Jun 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    C-terminal binding protein 2 interacts with JUNB to control macrophage inflammation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12149670/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Computer-aided molecular and biological-immune modeling of illicium verum bioactive compounds employing the Egyptian Nile snail Biomphalaria alexandrina as a paradigm
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    pmc.ncbi.nlm.nih.gov/articles/PMC12181124/
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    SpatialSNV: A novel method for identifying and analyzing spatially resolved SNVs in tumor microenvironments
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    pmc.ncbi.nlm.nih.gov/articles/PMC12166308/
  18. May 2025
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    Specific targeting of brain endothelial cells using enhancer AAV vectors
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    sciencedirect.com/science/article/pii/S089662732500251X
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    A tumour necrosis factor-α responsive cryptic promoter drives overexpression of the human endogenous retrovirus ERVK-7
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    sciencedirect.com/science/article/pii/S002192582500417X
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    Repeat-element RNAs integrate a neuronal growth circuit
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    sciencedirect.com/science/article/pii/S0092867425004982
  22. Apr 2025
  23. link.springer.com link.springer.com
    MiR-146/TNF-α/IL-6/osteocalcin crosstalk in anti-rheumatic potential of Galleria mellonella hemolymph from computational molecular modeling to in-vivo validation
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    link.springer.com/article/10.1007/s10822-025-00595-3
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    Investigation of the Role of the LC3 Conjugation System in Autophagy for Human Reward System Reactivity
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    biorxiv.org/content/10.1101/2025.03.26.645396v1
  25. Mar 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Association of Toll-like Receptor-9 Gene Single-Nucleotide Polymorphism and AK155(IL-26) Serum Levels with Chronic Obstructive Pulmonary Disease Exacerbation Risk: A Case-Controlled Study with Bioinformatics Analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11939906/
  27. Feb 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fusion oncoproteins and cooperating mutations define disease phenotypes in NUP98-rearranged leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11838931/
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    Exogenous BMI1 expression aggravates oral squamous cell carcinomas in tongue epithelia
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    sciencedirect.com/science/article/pii/S1476558625000259
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    Multiomic QTL mapping reveals phenotypic complexity of GWAS loci and prioritizes putative causal variants
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  31. Dec 2024
  32. biosignaling.biomedcentral.com biosignaling.biomedcentral.com
    CD69+CD103+CD8+ tissue-resident memory T cells possess stronger anti-tumor activity and predict better prognosis in colorectal cancer
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    Biliverdinuria Caused by Exonic BLVRA Deletions in Two Dogs with Green Urine
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  35. Nov 2024
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin
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    pmc.ncbi.nlm.nih.gov/articles/PMC11076809/
  37. Oct 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYC is Sufficient to Generate Mid-Life High-Grade Serous Ovarian and Uterine Serous Carcinomas in a p53-R270H Mouse Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC11425777/
  39. aacrjournals.org aacrjournals.org
    H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone
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    aacrjournals.org/cancerdiscovery/article/10/12/1968/2414/H3-3-G34W-Promotes-Growth-and-Impedes
  40. Aug 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long non-coding RNAs involved in Drosophila development and regeneration
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  42. www.biorxiv.org www.biorxiv.org
    A map of canine sequence variation relative to a Greenland wolf outgroup
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    biorxiv.org/content/10.1101/2024.06.03.597150v2
  43. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Chronic methamphetamine regulates the expression of MicroRNAs and putative target genes in the nucleus accumbens of mice
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23605/full
  44. Jul 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Pgb1 locus controls glycogen aggregation in astrocytes of the aged hippocampus without impacting cognitive function
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    ncbi.nlm.nih.gov/pmc/articles/PMC10690248/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Further evidence from DNAH12 supports favorable fertility outcomes of infertile males with dynein axonemal heavy chain gene family variants
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    pmc.ncbi.nlm.nih.gov/articles/PMC11278020/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Effect of Exposure to Neighborhood Violence on Glucocorticoid Receptor Signaling in Lung Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11221527/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Association of ESR1 Germline Variants with TP53 Somatic Variants in Breast Tumors in a Genome-wide Study
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    ncbi.nlm.nih.gov/pmc/articles/PMC11210444/
  49. Jun 2024
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The clock gene BHLHE40 and atypical CCNG2 control androgen-induced cellular senescence as a novel tumor suppressive pathway in prostate cancer
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  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct features of ribonucleotides within genomic DNA in Aicardi-Goutières syndrome ortholog mutants of Saccharomyces cerevisiae
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    ncbi.nlm.nih.gov/pmc/articles/PMC11166700/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Surgical tumour resection deregulates Hallmarks of Cancer in resected tissue and the surrounding microenvironment
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    ncbi.nlm.nih.gov/pmc/articles/PMC11148542/
  53. May 2024
  54. www.sciencedirect.com www.sciencedirect.com
    Heterochromatic 3D genome organization is directed by HP1a- and H3K9-dependent and independent mechanisms
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    sciencedirect.com/science/article/pii/S1097276524003952
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    Genomic landscape and tumor mutational features of resected preinvasive to invasive lung adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11128541/
  56. 52.53.155.43 52.53.155.43
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    Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas
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    sciencedirect.com/science/article/pii/S1535610824001314
  58. www.cell.com www.cell.com
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
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    cell.com/cell-genomics/fulltext/S2666-979X(24)00122-8
  59. Apr 2024
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Peripheral Blood B-Cell Subsets Frequency and Distribution and the BSF-2(IL-6) to CSIF:TGIF(IL-10) Ratio as Severity-Associated Signatures in Primary Open-Angle Glaucoma: A Case-Controlled Study
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    ncbi.nlm.nih.gov/pmc/articles/PMC10967876/
  61. Mar 2024
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N6-methyladenosine-associated genetic variants in NECTIN2 and HPCAL1 are risk factors for abdominal aortic aneurysm
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    ncbi.nlm.nih.gov/pmc/articles/PMC10952030/
  63. link.springer.com link.springer.com
    From degraded to deciphered: ATAC-seq’s application potential in forensic diagnosis
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    link.springer.com/article/10.1007/s00414-024-03206-2
  64. www.sciencedirect.com www.sciencedirect.com
    The transcription factor NF-κB orchestrates nucleosome remodeling during the primary response to Toll-like receptor 4 signaling
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    sciencedirect.com/science/article/pii/S1074761324000803
  65. Feb 2024
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson’s Disease Risk Enhancers in Microglia
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide p63-target gene analyses reveal TAp63/NRF2-dependent oxidative stress responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC10832605/
  68. Jan 2024
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function
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    ncbi.nlm.nih.gov/pmc/articles/PMC10769259/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10794847/
  71. Dec 2023
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative transcriptomics reveals human-specific cortical features
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    ncbi.nlm.nih.gov/pmc/articles/PMC10659116/
  73. Oct 2023
  74. www.science.org www.science.org
    Comparative transcriptomics reveals human-specific cortical features
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    science.org/doi/10.1126/science.ade9516
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omic profiling of the developing human cerebral cortex at the single-cell level
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    ncbi.nlm.nih.gov/pmc/articles/PMC10569714/
  76. www.nature.com www.nature.com
    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression
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    nature.com/articles/s41467-023-41927-x
  77. Sep 2023
  78. www.nature.com www.nature.com
    Defining the condensate landscape of fusion oncoproteins
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    nature.com/articles/s41467-023-41655-2
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15
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    ncbi.nlm.nih.gov/pmc/articles/PMC10520325/
  80. 52.53.155.43 52.53.155.43
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  81. link.springer.com link.springer.com
    Pan cancer characterization of genes whose expression has been associated with LINE-1 antisense promoter activity
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    link.springer.com/article/10.1186/s13100-023-00300-x
  82. link.springer.com link.springer.com
    Monocytes subsets altered distribution and dysregulated plasma hsa-miR-21-5p and hsa-miR-155-5p in HCV-linked liver cirrhosis progression to hepatocellular carcinoma
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    link.springer.com/article/10.1007/s00432-023-05313-w
  83. Aug 2023
  84. www.biorxiv.org www.biorxiv.org
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2
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    biorxiv.org/content/10.1101/2023.08.21.553157v1
  85. Jul 2023
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sox, Fox, and Lmx1b binding sites differentially regulate a Gdf5-Associated regulatory region during elbow development
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    ncbi.nlm.nih.gov/pmc/articles/PMC10364121/
  87. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Obesity during preclinical Alzheimer's disease development exacerbates brain metabolic decline
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15900
  88. Jun 2023
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The immunopeptidome from a genomic perspective: Establishing the non-canonical landscape of MHC class I–associated peptides
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    ncbi.nlm.nih.gov/pmc/articles/PMC10236148/
  90. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
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    aacrjournals.org/cancerres/article/83/5/735/716680/Enhanced-Glutaminolysis-Drives-Hypoxia-Induced
  91. May 2023
  92. 52.53.155.43 52.53.155.43
    The immunopeptidome from a genomic perspective: Establishing the non-canonical landscape of MHC class I-associated peptides.
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    52.53.155.43/7542579df6ee0937b796dbe6d53f5afff991f7fc/RRID2-html.html
  93. www.nature.com www.nature.com
    Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response
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    nature.com/articles/s41467-023-38271-5
  94. Apr 2023
  95. www.sciencedirect.com www.sciencedirect.com
    Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia
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    sciencedirect.com/science/article/pii/S2211124723003844
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intronic Cis-Element DR8 in hTERT Is Bound by Splicing Factor SF3B4 and Regulates hTERT Splicing in Non-Small Cell Lung Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9532359/
  97. Mar 2023
  98. www.sciencedirect.com www.sciencedirect.com
    Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion
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    sciencedirect.com/science/article/pii/S1097276523001533
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    In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution
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    sciencedirect.com/science/article/pii/S2666979X23000368
  100. www.sciencedirect.com www.sciencedirect.com
    Gene-by-environment interactions are pervasive among natural genetic variants
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    sciencedirect.com/science/article/pii/S2666979X23000332
  101. www.sciencedirect.com www.sciencedirect.com
    Widespread epistasis among beneficial genetic variants revealed by high-throughput genome editing
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    sciencedirect.com/science/article/pii/S2666979X23000162
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The first Antechinus reference genome provides a resource for investigating the genetic basis of semelparity and age-related neuropathologies
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    ncbi.nlm.nih.gov/pmc/articles/PMC9631953/
  103. Dec 2022
  104. aacrjournals.org aacrjournals.org
    TFAP4 activates IGF2BP1 and promotes progression of non-small cell lung cancer by stabilizing TK1 expression through m6A modification
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    aacrjournals.org/mcr/article/20/12/1763/711001/TFAP4-Activates-IGF2BP1-and-Promotes-Progression
  105. Nov 2022
  106. www.sciencedirect.com www.sciencedirect.com
    De-erosion of X chromosome dosage compensation by the editing of XIST regulatory regions restores the differentiation potential in hPSCs
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    sciencedirect.com/science/article/pii/S2667237522002491
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    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
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    sciencedirect.com/science/article/abs/pii/S1097276522010644
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    STAT3 is activated by CTGF-mediated tumor-stroma cross talk to promote HCC progression.
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    sciencedirect.com/science/article/pii/S2352345X22001989
  109. Sep 2022
  110. www.sciencedirect.com www.sciencedirect.com
    A natural transdifferentiation event involving mitosis is empowered by integrating signaling inputs with conserved plasticity factors
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    sciencedirect.com/science/article/pii/S2211124722011974
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic and prognostic potential of GPCRs in prostate cancer from multi-omics landscape
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    ncbi.nlm.nih.gov/pmc/articles/PMC9468875/
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reversible epigenetic alterations regulate class I HLA loss in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437063/
  113. Aug 2022
  114. 52.53.155.43 52.53.155.43
    mcr-21-0058-html.html
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    Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development
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    Landscape of histone modifications in a sponge reveals the origin of animal cis-regulatory complexity
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    A Methyl-Balanced Diet Prevents CRF-Induced Prenatal Stress-Triggered Predisposition to Binge Eating-like Phenotype
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    Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth
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    Stem Cell Lineage Infidelity Drives Wound Repair and Cancer
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    Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly with a Rare Lissencephaly Variant
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    Splicing repression allows the gradual emergence of new Alu-exons in primate evolution
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    Co-option of an endogenous retrovirus envelope for host defense in hominid ancestors
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    The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries
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    Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets
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    Layer-specific chromatin accessibility landscapes reveal regulatory networks in adult mouse visual cortex
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    Mutations in Human Accelerated Regions Disrupt Cognition and Social Behavior
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    RNA Binding to CBP Stimulates Histone Acetylation and Transcription
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    A network of epigenetic modifiers and DNA repair genes controls tissue-specific copy number alteration preference
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