51 Matching Annotations
  1. Last 7 days
  2. journals.asm.org journals.asm.org
    Molecular mechanism of resistance to lonafarnib conferred by mutations in the cysteine-rich region of respiratory syncytial virus fusion glycoprotein and discovery of a lonafarnib-derived antiviral PROTAC
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    journals.asm.org/doi/10.1128/jvi.01487-25
  3. Oct 2025
  4. www.sciencedirect.com www.sciencedirect.com
    Deciphering genomic evolution of metastatic organotropism with 535 paired primary lung cancers and metastases
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    sciencedirect.com/science/article/pii/S2211124725012203
  5. Sep 2025
  6. pathsocjournals.onlinelibrary.wiley.com pathsocjournals.onlinelibrary.wiley.com
    Tracing metastatic spread in pediatric solid tumors using copy number and targeted deep sequencing
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    pathsocjournals.onlinelibrary.wiley.com/doi/10.1002/path.6472
  7. Aug 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genomic Signatures of Poor Prognosis in Merkel Cell Carcinoma: A Single-Institution Prospective Study
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    pmc.ncbi.nlm.nih.gov/articles/PMC12336863/
  9. Jul 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Circulating tumor DNA monitoring detects minimal residual disease and predicts outcomes in patients with esophageal adenocarcinoma or squamous cell carcinoma after esophagectomy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12290085/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genomic and epigenomic analysis of plasma cell-free DNA identifies stemness features associated with worse survival in lethal prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11743868/
  12. May 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    M6Allele: a toolkit for detection of allele-specific RNA N6-methyladenosine modifications
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    pmc.ncbi.nlm.nih.gov/articles/PMC12087454/
  14. Mar 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Characteristics and filtering of low-frequency artificial short deletion variations based on nanopore sequencing
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    pmc.ncbi.nlm.nih.gov/articles/PMC11927395/
  16. Feb 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fusion oncoproteins and cooperating mutations define disease phenotypes in NUP98-rearranged leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11838931/
  18. www.sciencedirect.com www.sciencedirect.com
    Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy
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    sciencedirect.com/science/article/pii/S1934590925000025
  19. Jan 2025
  20. link.springer.com link.springer.com
    Sex disparities in the association between rare earth elements exposure and genetic mutation frequencies in lung cancer patients
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    link.springer.com/article/10.1038/s41598-024-79580-z
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increased local DNA methylation disorder in AMLs with DNMT3A-destabilizing variants and its clinical implication
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    pmc.ncbi.nlm.nih.gov/articles/PMC11724044/
  22. Dec 2024
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive genomic characterization of hematologic malignancies at a pediatric tertiary care center
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    pmc.ncbi.nlm.nih.gov/articles/PMC11647012/
  24. Oct 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical value of liquid biopsy in FGFR2 fusion-positive cholangiocarcinoma patients during targeted therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443220/
  26. May 2024
  27. www.sciencedirect.com www.sciencedirect.com
    Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma
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    sciencedirect.com/science/article/pii/S1535610824001363
  28. Feb 2024
  29. 52.53.155.43 52.53.155.43
    can-23-1129-html.html
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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Natural history of germline BRCA1 mutated and BRCA wild-type triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10865976/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Immunogenomic Landscape of Neuroendocrine Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10524949/
  32. Jan 2024
  33. jtd.amegroups.org jtd.amegroups.org
    Dissecting the genetic variations associated with response to first-line chemotherapy in patients with small cell lung cancer: a retrospective cohort study
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    jtd.amegroups.org/article/view/81699/html
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging tissue-specific enhancer-target gene regulatory networks identifies enhancer somatic mutations that functionally impact lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10758689/
  35. Dec 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10715669/
  37. 52.53.155.43 52.53.155.43
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  38. Nov 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Unveiling the metal mutation nexus: Exploring the genomic impacts of heavy metal exposure in lung adenocarcinoma and colorectal cancer
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    sciencedirect.com/science/article/pii/S0304389423018733
  40. Oct 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Associations between AI-Assisted Tumor Amphiregulin and Epiregulin IHC and Outcomes from Anti-EGFR Therapy in the Routine Management of Metastatic Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10570673/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Colorectal Cancer Organoid–Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC10551667/
  43. Sep 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identifying mechanisms of resistance by circulating tumour DNA in EVOLVE, a Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer at time of PARP Inhibitor Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10502468/
  45. www.nature.com www.nature.com
    A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors
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    nature.com/articles/s42003-023-05320-0
  46. Jun 2023
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Latent class analysis-derived classification improves the cancer-specific death stratification of molecular subtyping in colorectal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10290127/
  48. Apr 2023
  49. link.springer.com link.springer.com
    Genomic profiling of idiopathic peri-hilar cholangiocarcinoma reveals new targets and mutational pathways
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    link.springer.com/article/10.1038/s41598-023-33096-0
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structurally Complex Osteosarcoma Genomes Exhibit Limited Heterogeneity within Individual Tumors and across Evolutionary Time
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    ncbi.nlm.nih.gov/pmc/articles/PMC10093779/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Application of Genomic Sequencing to Refine Patient Stratification for Adjuvant Therapy in Renal Cell Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10068441/
  52. Feb 2023
  53. www.mdpi.com www.mdpi.com
    Gain of Aggressive Histological and Molecular Patterns after Acquired Resistance to Novel Anti-EGFR Therapies in Non-Small Cell Lung Cancer
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    mdpi.com/1422-0067/24/4/3802
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9780084/
  55. Dec 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Relative infectivity of the SARS-CoV-2 Omicron variant in human alveolar cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9659354/
  57. Nov 2022
  58. www.nature.com www.nature.com
    Microsatellite instability detection in breast cancer using drop-off droplet digital PCR
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    nature.com/articles/s41388-022-02504-6
  59. Jul 2022
  60. www.sciencedirect.com www.sciencedirect.com
    Spatiotemporal genomic analysis reveals distinct molecular features in recurrent stage I non-small cell lung cancers
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    sciencedirect.com/science/article/pii/S2211124722008415
  61. Jun 2022
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Humanized Animal Model Predicts Clonal Evolution and Therapeutic Vulnerabilities in Myeloproliferative Neoplasms
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    ncbi.nlm.nih.gov/pmc/articles/PMC8716669/
  63. Apr 2022
  64. jeccr.biomedcentral.com jeccr.biomedcentral.com
    Growth factor independence underpins a paroxysmal, aggressive Wnt5aHigh/EphA2Low phenotype in glioblastoma stem cells, conducive to experimental combinatorial therapy
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    jeccr.biomedcentral.com/articles/10.1186/s13046-022-02333-1/tables/2
  65. Feb 2022
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-Omics Profiling Suggesting Intratumoral Mast Cells as Predictive Index of Breast Cancer Lung Metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8801492/
  67. Dec 2021
  68. www.sciencedirect.com www.sciencedirect.com
    Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight
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    sciencedirect.com/science/article/pii/S266637912100344X
  69. Nov 2021
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ploidy and recombination proficiency shape the evolutionary adaptation to constitutive DNA replication stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC8604288/
  71. Oct 2021
  72. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Targeted molecular characterization of external auditory canal squamous cell carcinomas
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    onlinelibrary.wiley.com/doi/10.1002/lio2.654
  73. Jul 2021
  74. academic.oup.com academic.oup.com
    Sex-Biased Gene Expression and Dosage Compensation on the Artemia franciscana Z-Chromosome
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    academic.oup.com/gbe/article/11/4/1033/5378701
  75. Mar 2021
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery
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    ncbi.nlm.nih.gov/pmc/articles/PMC7960510/
  77. Nov 2020
  78. academic.oup.com academic.oup.com
    CopyDetective: Detection threshold–aware copy number variant calling in whole-exome sequencing data
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    academic.oup.com/gigascience/article/9/11/giaa118/5949275
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-Dimensional Human Alveolar Stem Cell Culture Models Reveal Infection Response to SARS-CoV-2
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    ncbi.nlm.nih.gov/pmc/articles/PMC7577700/
  80. Jan 2020
  81. www.sciencedirect.com www.sciencedirect.com
    GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability
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    sciencedirect.com/science/article/pii/S1534580719309372
  82. www.sciencedirect.com www.sciencedirect.com
    A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity
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    sciencedirect.com/science/article/pii/S0092867419313212
  83. Nov 2018
  84. www.sciencedirect.com www.sciencedirect.com
    Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma
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    sciencedirect.com/science/article/pii/S2211124718315675
  85. www.sciencedirect.com www.sciencedirect.com
    The Rise and Fall of African Rice Cultivation Revealed by Analysis of 246 New Genomes
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    sciencedirect.com/science/article/pii/S0960982218307024
  86. Nov 2017
  87. elifesciences.org elifesciences.org
    Pilot study of large-scale production of mutant pigs by ENU mutagenesis
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    elifesciences.org/articles/26248