337 Matching Annotations
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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12508145/
  3. Oct 2025
  4. www.sciencedirect.com www.sciencedirect.com
    Targeted citrullination enables p53 binding to non-canonical sites
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    sciencedirect.com/science/article/pii/S1097276525007452
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    Arsenic regulates ALKBH1 abundance and substrate specificity to promote translation and tumorigenicity
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    sciencedirect.com/science/article/pii/S2211124725010824
  6. Sep 2025
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    Dual EZH1/2 inhibition enhances DNMT inhibitor efficacy in colon cancer through targeting H3K27me1
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    biorxiv.org/content/10.1101/2025.09.16.676613v1
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    Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state
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    sciencedirect.com/science/article/pii/S2211124725009568
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    Seclidemstat (SP-2577) Induces Transcriptomic Reprogramming and Cytotoxicity in Multiple Fusion–Positive Sarcomas
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    CA-125 as a Biomarker in Renal Medullary Carcinoma: Integrated Molecular Profiling, Functional Characterization, and Prospective Clinical Validation
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    A framework to mine laser microdissection-based omics data and uncover regulators of pancreatic cancer heterogeneity
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    DeepAnnotation: A novel interpretable deep learning–based genomic selection model that integrates comprehensive functional annotations
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    Machine learning-based identification of a transcriptomic blood signature discriminating between systemic autoimmunity and infection
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    sciencedirect.com/science/article/pii/S2666634025002673
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    Synthetic ZFTA fusions pinpoint disordered protein domain acquisition as a mechanism of brain tumorigenesis
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    nature.com/articles/s41556-025-01745-3
  15. Aug 2025
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    Transient gene melting governs the timing of oligodendrocyte maturation
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    sciencedirect.com/science/article/pii/S009286742500861X
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    Evaluating Gene Fusions as Prognostic Biomarkers and Therapeutic Targets in Immune Checkpoint Blockade-Treated Advanced Melanoma: a Retrospective Analysis.
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    Genomic Signatures of Poor Prognosis in Merkel Cell Carcinoma: A Single-Institution Prospective Study
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    pmc.ncbi.nlm.nih.gov/articles/PMC12336863/
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    NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers
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    nature.com/articles/s41586-025-09299-y
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The catalytic efficiency of METTL16 affects cellular processes by governing the intracellular S-adenosylmethionine setpoint
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    pmc.ncbi.nlm.nih.gov/articles/PMC12330366/
  21. elifesciences.org elifesciences.org
    Identification and characterization of early human photoreceptor states and cell-state-specific retinoblastoma-related features
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    elifesciences.org/articles/101918
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CTG-Initiated Cryptic Peptide Translation Up- and Downstream of a Canonical ATG Start Codon Is Enhanced by TLR Stimulation and Induces Tumor Regression in Mice
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  23. Jul 2025
  24. www.biorxiv.org www.biorxiv.org
    RUNX2 inhibition disrupts a PAX3::FOXO1-RUNX2 feed-forward loop and dismantles oncogenic gene programs in fusion-positive rhabdomyosarcoma
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    High PER1 expression is associated with STK11 mutation and clinical biomarkers of immunotherapy resistance in lung adenocarcinoma
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    link.springer.com/article/10.1007/s00432-025-06269-9
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    Cellular crosstalk mediated by TGF-β drives epithelial-mesenchymal transition in patient-derived multi-compartment biliary organoids
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    nature.com/articles/s41467-025-61442-5
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    Multiomics uncovers the epigenomic and transcriptomic response to viral and bacterial stimulation in turbot
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    The catalytic efficiency of METTL16 affects cellular processes by governing the intracellular S-adenosylmethionine setpoint
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  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiparity induces persistent myocardial structural, functional and transcriptomic remodelling in mice
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    TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice
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  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exposing the DNA methylation-responsive compartment of the leukaemic genome in T-ALL cell lines support its potential as a novel therapeutic target in T-ALL
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    Molecular and genetic evidence for the role of AMBRA1 in suppressing S-phase entry and tumorigenesis - ScienceDirect-html.html
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    Enhancer Hijacking Discovery in Acute Myeloid Leukemia by Pyjacker Identifies MNX1 Activation via Deletion 7q
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    High-Throughput Drug Screening of Clear Cell Ovarian Cancer Organoids Reveals Vulnerability to Proteasome Inhibitors and Dinaciclib and Identifies AGR2 as a Therapeutic Target
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  35. Jun 2025
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    Integrating comparative genomics and risk classification by assessing virulence, antimicrobial resistance, and plasmid spread in microbial communities with gSpreadComp
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    Chromosome-Level genome assembly and transcriptome analysis of the ural owl, Strix uralensis Pallas, 1771
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    Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expression
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    NDF/GLYR1 Promotes RNA Polymerase II Processivity via Pol II Binding and Nucleosome Destabilization
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    Spatial–Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune Microenvironment
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    Chromosome-level genome assembly and methylome profile yield insights for the conservation of endangered loggerhead sea turtles
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    P4HA1 Mediates Hypoxia-Induced Invasion in Human Pancreatic Cancer Organoids
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  46. May 2025
  47. www.nature.com www.nature.com
    Whole-genome sequencing analyses suggest novel genetic factors associated with Alzheimer’s disease and a cumulative effects model for risk liability
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    hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation
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  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Diacylglycerol Kinase ζ Attenuates Doxorubicin‐Induced Cardiotoxicity Through p53 Degradation
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    Clear-Cell Renal Cell Carcinoma Molecular Subtypes Differ by African and European Genetic Similarity
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    DNA methyltransferase 1 modulates mitochondrial function through bridging m5C RNA methylation
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  53. Apr 2025
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia
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    Cross-ancestry genome-wide association study identifies implications of SORL1 in cerebral beta-amyloid deposition
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  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pre-existing skin-resident CD8 and γδ T cell circuits mediate immune response in Merkel cell carcinoma and predict immunotherapy efficacy
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  58. Mar 2025
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    Lineage contribution of the mesendoderm progenitors in the gastrulating mouse embryo
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    Antagonistic roles for MITF and TFE3 in melanoma plasticity
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    Healthy microbiome—moving towards functional interpretation
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    The carnosinase dipeptidase CNDP1 is a novel metabolic vulnerability in brain metastasis
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    Enhancer transcription profiling reveals an enhancer RNA-driven ferroptosis and new therapeutic opportunities in prostate cancer
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  65. Feb 2025
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antimicrobial Resistance in Pasteurella multocida Isolates from Bovine Mastitis Can Be Associated with Multidrug-Resistance-Mediating Integrative and Conjugative Elements (ICEs)
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    Fusion oncoproteins and cooperating mutations define disease phenotypes in NUP98-rearranged leukemia
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    Microevolution of Cryptococcus neoformans in high CO2 converges on mutations isolated from patients with relapsed cryptococcosis
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    Dynamic changes in gene expression of growing nonhuman primate antral follicles
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    Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte progenitors
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    Repurposing statins and phenothiazines to treat chemoresistant neuroblastoma
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    biorxiv.org/content/10.1101/2025.01.28.635193v1
  72. Jan 2025
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    Steatohepatitis-induced vascular niche alterations promote melanoma metastasis
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    link.springer.com/article/10.1186/s40170-025-00374-6
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    Protocol for transcriptomic and epigenomic analyses of tip-like endothelial cells using scRNA-seq and ChIP-seq
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    Ligand-Independent Vitamin D Receptor Actions Essential for Keratinocyte Homeostasis in the Skin
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    Increased local DNA methylation disorder in AMLs with DNMT3A-destabilizing variants and its clinical implication
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    Hypoxia drives the formation of lung micropapillary adenocarcinoma-like structure through hypoxia-inducible factor-1α
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    Splenic fibroblasts control marginal zone B cell movement and function via two distinct Notch2-dependent regulatory programs
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    sciencedirect.com/science/article/pii/S1074761324005673
  79. Dec 2024
  80. elifesciences.org elifesciences.org
    Single-cell transcriptomics of vomeronasal neuroepithelium reveals a differential endoplasmic reticulum environment amongst neuronal subtypes
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    elifesciences.org/articles/98250
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    H4K20me3-Mediated Repression of Inflammatory Genes is a Characteristic and Targetable Vulnerability of Persister Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617193/
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    Functional annotation of regulatory elements in rainbow trout uncovers roles of the epigenome in genetic selection and genome evolution
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    Single chromatin fiber profiling and nucleosome position mapping in the human brain
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    sciencedirect.com/science/article/pii/S2667237524003011
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    DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states
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    The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release
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    Nuclear Factor I family members are key transcription factors regulating gene expression
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    Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems
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  88. Nov 2024
  89. www.sciencedirect.com www.sciencedirect.com
    CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity
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    sciencedirect.com/science/article/pii/S1934590924003692
  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11532787/
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  92. Oct 2024
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An in vitro approach reveals molecular mechanisms underlying endocrine disruptor-induced epimutagenesis
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  94. www.nature.com www.nature.com
    Discovery of two new actinobacteria, Micromonospora palythoicola sp. nov. and Streptomyces poriticola sp. nov., isolated from marine invertebrates
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  95. Sep 2024
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide DNA methylation sequencing reveals the involvement of ferroptosis in hepatotoxicity induced by dietary exposure to food-grade titanium dioxide
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    Disentangling river and swamp buffalo genetic diversity: initial insights from the 1000 Buffalo Genomes Project
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  189. Jul 2023
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  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  200. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  203. www.sciencedirect.com www.sciencedirect.com
    5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling
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    Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones
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  206. May 2023
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    Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks
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  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  209. journals.asm.org journals.asm.org
    Genomic Diversity of Methicillin-Resistant Staphylococcus aureus CC398 Isolates Collected from Diseased Swine in the German National Resistance Monitoring Program GERM-Vet from 2007 to 2019
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  210. www-sciencedirect-com.ezproxy.auckland.ac.nz www-sciencedirect-com.ezproxy.auckland.ac.nz
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  211. Apr 2023
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    Cell-Free Urine and Plasma DNA Mutational Analysis Predicts Neoadjuvant Chemotherapy Response and Outcome in Patients with Muscle-Invasive Bladder Cancer
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  213. www.sciencedirect.com www.sciencedirect.com
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  214. www.mdpi.com www.mdpi.com
    BlockmiR AONs as Site-Specific Therapeutic MBNL Modulation in Myotonic Dystrophy 2D and 3D Muscle Cells and HSALR Mice
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  215. Mar 2023
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  219. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  220. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  222. Feb 2023
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  224. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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