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  1. Last 7 days
  2. www.cell.com www.cell.com
    Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine
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    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.chom.2024.06.003

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    cell.com/cell-host-microbe/abstract/S1931-3128(24)00197-5
  3. www.sciencedirect.com www.sciencedirect.com
    miRNA-mediated inhibition of an actomyosin network in hippocampal pyramidal neurons restricts sociability in adult male mice
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    1. scibot 18 Jul 2024
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    sciencedirect.com/science/article/pii/S2211124724007587
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    ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma
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    1. scibot 18 Jul 2024
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    sciencedirect.com/science/article/pii/S2211124724007356
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    Synaptic plasticity in human thalamocortical assembloids
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    1. scibot 17 Jul 2024
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    sciencedirect.com/science/article/pii/S2211124724008325
  6. Jul 2024
  7. www.tandfonline.com www.tandfonline.com
    SIGLEC15, negatively correlated with PD-L1 in HCC, could induce CD8+ T cell apoptosis to promote immune evasion
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    1. scibot 12 Jul 2024
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      DOI: 10.1080/2162402X.2024.2376264

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    tandfonline.com/doi/abs/10.1080/2162402X.2024.2376264
  8. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ABC Efflux Transporters and Solute Carriers in the Early Developing Brain of a Marsupial Monodelphis domestica (South American Gray Short-Tailed Opossum)
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    1. scibot 12 Jul 2024
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      DOI: 10.1002/cne.25655

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    onlinelibrary.wiley.com/doi/full/10.1002/cne.25655
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNF185 control of COL3A1 expression limits prostate cancer migration and metastatic potential
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    1. scibot 07 Jul 2024
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      DOI: 10.1158/1541-7786.MCR-23-0512

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    ncbi.nlm.nih.gov/pmc/articles/PMC10841372/
  10. Jun 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early detection and diagnosis of cancer with interpretable machine learning to uncover cancer-specific DNA methylation patterns
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    1. scibot 22 Jun 2024
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      DOI: 10.1093/biomethods/bpae028

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      DOI: 10.1093/biomethods/bpae028

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    ncbi.nlm.nih.gov/pmc/articles/PMC11186673/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uncovering strain- and age-dependent innate immune responses to SARS-CoV-2 infection in air-liquid-interface cultured nasal epithelia
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    1. scibot 14 Jun 2024
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      DOI: 10.1016/j.isci.2024.110009

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    ncbi.nlm.nih.gov/pmc/articles/PMC11166695/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phase I trial of viral vector based personalized vaccination elicits robust neoantigen specific antitumor T cell responses
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    1. scibot 07 Jun 2024
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      DOI: 10.1158/1078-0432.CCR-23-3940

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    ncbi.nlm.nih.gov/pmc/articles/PMC11145154/
  14. www.sciencedirect.com www.sciencedirect.com
    Cell-type-specific effects of age and sex on human cortical neurons
    1
    1. scibot 05 Jun 2024
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    sciencedirect.com/science/article/pii/S089662732400360X
  15. May 2024
  16. 52.53.155.43 52.53.155.43
    ccr-23-3940-html.html
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    1. scibot 23 May 2024
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  17. aacrjournals.org aacrjournals.org
    An endosomal acid-regulatory feedback system rewires cytosolic cAMP metabolism and drives tumour progression
    1
    1. scibot 23 May 2024
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      DOI: 10.1158/1541-7786.MCR-23-0606

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    aacrjournals.org/mcr/article/22/5/465/743199/An-Endosomal-Acid-Regulatory-Feedback-System
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    The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
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    1. scibot 23 May 2024
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      DOI: 10.1016/j.immuni.2024.04.026

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    sciencedirect.com/science/article/pii/S1074761324002310
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer
    1
    1. scibot 22 May 2024
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      DOI: 10.1158/2767-9764.CRC-23-0639

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    ncbi.nlm.nih.gov/pmc/articles/PMC11104289/
  20. www.sciencedirect.com www.sciencedirect.com
    The Janus kinase 1 is critical for pancreatic cancer initiation and progression
    1
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    sciencedirect.com/science/article/pii/S2211124724005308
  21. www.medrxiv.org www.medrxiv.org
    Proliferative History Is a Novel Driver of Clinical Outcome in Splenic Marginal Zone Lymphoma
    1
    1. scibot 03 May 2024
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      DOI: 10.1101/2024.01.16.24301320

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    medrxiv.org/content/10.1101/2024.01.16.24301320v1
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Multi-Omic Assessment of Pioglitazone in Skeletal Muscles of Mice Implanted with Human HER2/neu Overexpressing Breast Cancer Xenografts
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    1. scibot 03 May 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11042380/
  23. www.cell.com www.cell.com
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
    1
    1. scibot 02 May 2024
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      DOI: 10.1016/j.xgen.2024.100556

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    cell.com/cell-genomics/fulltext/S2666-979X(24)00122-8
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modeling Myeloma Dissemination In Vitro with hMSC-interacting Subpopulations of INA-6 Cells and Their Aggregation/Detachment Dynamics
    1
    1. scibot 01 May 2024
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      DOI: 10.1158/2767-9764.CRC-23-0411

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    ncbi.nlm.nih.gov/pmc/articles/PMC11057410/
  25. Apr 2024
  26. www.sciencedirect.com www.sciencedirect.com
    Single-cell senescence identification reveals senescence heterogeneity, trajectory, and modulators
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.cmet.2024.03.009

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    sciencedirect.com/science/article/pii/S1550413124000883
  27. www.sciencedirect.com www.sciencedirect.com
    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
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    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114065

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    sciencedirect.com/science/article/pii/S2211124724003930
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti–PD-1 Therapy
    1
    1. scibot 05 Apr 2024
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      DOI: 10.1158/2326-6066.CIR-23-0486

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    ncbi.nlm.nih.gov/pmc/articles/PMC10985468/
  29. Mar 2024
  30. www.sciencedirect.com www.sciencedirect.com
    Chromosome level genome assembly and transcriptome analysis of E11 cells infected by tilapia lake virus
    1
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      DOI: 10.1016/j.fsi.2024.109505

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    sciencedirect.com/science/article/pii/S1050464824001499
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptome-informed identification and characterisation of Planococcus citri cis- and trans-isoprenyl diphosphate synthase genes
    1
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      DOI: 10.1016/j.isci.2024.109441

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    ncbi.nlm.nih.gov/pmc/articles/PMC10960109/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA methylation-environment interactions in the human genome
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    1. scibot 17 Mar 2024
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      DOI: 10.7554/eLife.89371

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  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single cell transcriptome analysis of the THY-Tau22 mouse model of Alzheimer’s disease reveals sex-dependent dysregulations
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    1. scibot 12 Mar 2024
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      DOI: 10.1038/s41420-024-01885-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10920792/
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    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
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    1. scibot 01 Mar 2024
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      DOI: 10.1016/j.cmet.2023.12.010

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    sciencedirect.com/science/article/pii/S1550413123004618
  35. Feb 2024
  36. www.sciencedirect.com www.sciencedirect.com
    Sustained antidepressant effects of ketamine metabolite involve GABAergic inhibition-mediated molecular dynamics in aPVT glutamatergic neurons
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    sciencedirect.com/science/article/pii/S0896627324000497
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach
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      DOI: 10.1158/1078-0432.CCR-23-0873

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    ncbi.nlm.nih.gov/pmc/articles/PMC10870121/
  38. link.springer.com link.springer.com
    AHRR and SFRP2 in primary versus recurrent high-grade serous ovarian carcinoma and their prognostic implication
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      DOI: 10.1038/s41416-023-02550-1

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    link.springer.com/article/10.1038/s41416-023-02550-1
  39. www.biorxiv.org www.biorxiv.org
    A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer
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      DOI: 10.1101/2023.12.10.570854

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    biorxiv.org/content/10.1101/2023.12.10.570854v1
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic background variation impacts microglial heterogeneity and disease progression in amyotrophic lateral sclerosis model mice
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      DOI: 10.1016/j.isci.2024.108872

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    ncbi.nlm.nih.gov/pmc/articles/PMC10839647/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson’s Disease Risk Enhancers in Microglia
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      DOI: 10.1016/j.isci.2024.108921

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    ncbi.nlm.nih.gov/pmc/articles/PMC10845915/
  42. www.nature.com www.nature.com
    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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      DOI: 10.1038/s41467-024-45067-8

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    nature.com/articles/s41467-024-45067-8
  43. www.sciencedirect.com www.sciencedirect.com
    Embigin deficiency leads to delayed embryonic lung development and high neonatal mortality in mice
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      DOI: 10.1016/j.isci.2024.108914

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    sciencedirect.com/science/article/pii/S2589004224001354
  44. www.biorxiv.org www.biorxiv.org
    Mapping chromatin state and transcriptional response in CIC-DUX4 undifferentiated round cell sarcoma
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    1. scibot 04 Feb 2024
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      DOI: 10.1101/2023.10.11.561932

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    biorxiv.org/content/10.1101/2023.10.11.561932v1
  45. Jan 2024
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The evolution of constitutively active humoral immune defenses in Drosophila populations under high parasite pressure
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      DOI: 10.1371/journal.ppat.1011729

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    ncbi.nlm.nih.gov/pmc/articles/PMC10807768/
  47. www.sciencedirect.com www.sciencedirect.com
    Discrete prefrontal neuronal circuits determine repeated stress-induced behavioral phenotypes in male mice
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      DOI: 10.1016/j.neuron.2023.12.004

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    sciencedirect.com/science/article/pii/S0896627323009340
  48. 52.53.155.43 52.53.155.43
    FOXP1 regulates the development of excitatory synaptic inputs onto striatal neurons and induces phenotypic reversal with reinstatement
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  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
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    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
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  51. Dec 2023
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    Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection.
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    Machine learning analysis of the T cell receptor repertoire identifies sequence features of self-reactivity
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  54. Nov 2023
  55. www.biorxiv.org www.biorxiv.org
    Age-induced midbrain-striatum assembloids model early phenotypes of Parkinson’s disease
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Divergence of TORC1-mediated stress response leads to novel acquired stress resistance in a pathogenic yeast
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    Combination Therapies to Improve the Efficacy of Immunotherapy in Triple-negative Breast Cancer
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    Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids
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  59. Oct 2023
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    Loss of succinyl-CoA synthetase in mouse forebrain results in hypersuccinylation with perturbed neuronal transcription and metabolism
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    CD39+ conventional CD4+ T cells with exhaustion traits and cytotoxic potential infiltrate tumors and expand upon CTLA-4 blockade
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    CCR5 promotes the migration of CD8+ T cells to the leishmanial lesions
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    The evolution of constitutively active humoral immune defenses in Drosophila populations under high parasite pressure
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    Transcriptomic and proteomic profiling reveals distinct pathogenic features of peripheral non-classical monocytes in systemic lupus erythematosus
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  65. www.nature.com www.nature.com
    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression
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  66. Sep 2023
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    Molecularly targetable cell types in mouse visual cortex have distinguishable prediction error responses
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    Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice
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  69. Aug 2023
  70. www.biorxiv.org www.biorxiv.org
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRAF7 is an essential regulator of blood vessel integrity during mouse embryonic and neonatal development
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    Gene expression genetics of the striatum of Diversity Outbred mice
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    Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression
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    Early clonal extinction in glioblastoma progression revealed by genetic barcoding
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    Clinical features associated with outcomes and biomarker analysis of dabrafenib plus trametinib treatment in patients with BRAF-mutant melanoma brain metastases
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  76. Jul 2023
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    Genomic analyses provide insights into the evolution and salinity adaptation of halophyte Tamarix chinensis
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    Bacterial clade-specific analysis identifies distinct epithelial responses in inflammatory bowel disease
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    A network-based approach reveals long non-coding RNAs associated with disease activity in lupus nephritis: key pathways for flare and potential biomarkers to be used as liquid biopsies
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    TIMP3 promotes the maintenance of neural stem-progenitor cells in the mouse subventricular zone
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    Low-level repressive histone marks fine-tune gene transcription in neural stem cells
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      DOI: 10.7554/eLife.86127

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    Customization of the translational complex regulates mRNA-specific translation to control CNS regeneration
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    Immunological modifications following chemotherapy are associated with delayed recurrence of ovarian cancer
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    Antigen presentation by clonally diverse CXCR5+ B cells to CD4 and CD8 T cells is associated with durable response to immune checkpoint inhibitors
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    Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses
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  86. Jun 2023
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of transcriptional regulatory variants in pig duodenum, liver, and muscle tissues
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  89. www.biorxiv.org www.biorxiv.org
    Divergence of TORC1-mediated Stress Response Leads to Novel Acquired Stress Resistance in a Pathogenic Yeast
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    DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres
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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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    Targeted MDM2 degradation reveals a new vulnerability for p53 inactivated triple negative breast cancer
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  93. dx.doi.org dx.doi.org
    NAD + Metabolism Generates a Metabolic Vulnerability in Endocrine-Resistant Metastatic Breast Tumors in Females
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  94. May 2023
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks
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    Several cell-intrinsic effectors drive type I interferon-mediated restriction of HIV-1 in primary CD4+ T cells
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    Phenotypic diversity of T cells in human primary and metastatic brain tumors revealed by multiomic interrogation
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    Immune microenvironment remodeling after radiation of a progressing brain metastasis
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  99. www.biorxiv.org www.biorxiv.org
    Gene expression genetics of the striatum of Diversity Outbred mice
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    Network analysis reveals a major role for 14q32 cluster miRNAs in determining transcriptional differences between IGHV-mutated and unmutated CLL
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer
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  102. Apr 2023
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    A network perspective on the ecology of gut microbiota and progression of type 2 diabetes: Linkages to keystone taxa in a Mexican cohort
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    Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects
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  105. aacrjournals.org aacrjournals.org
    Multi-substrate metabolic tracing reveals marked heterogeneity and dependency on fatty acid metabolism in human prostate cancer
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells
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    Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia
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    Asparagine starvation suppresses histone demethylation through iron depletion
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    Integrative omics-analysis of lipid metabolism regulation by peroxisome proliferator-activated receptor a and b agonists in male Atlantic cod
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    CD39+ conventional CD4+ T cells with exhaustion traits and cytotoxic potential infiltrate tumors and expand upon CTLA-4 blockade
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  111. Mar 2023
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    Neuronal identity defines α-synuclein and tau toxicity
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    Inactivation of interleukin-30 in colon cancer stem cells via CRISPR/Cas9 genome editing inhibits their oncogenicity and improves host survival
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    Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion
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    A central chaperone-like role for 14-3-3 proteins in human cells
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  116. link.springer.com link.springer.com
    Expression of down-regulated ERV LTR elements associates with immune activation in human small-cell lung cancers
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      DOI: 10.1186/s13100-023-00290-w

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  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Several cell-intrinsic effectors drive type I interferon-mediated restriction of HIV-1 in primary CD4+ T cells
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  118. Feb 2023
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    PRC2 Heterogeneity Drives Tumor Growth in Medulloblastoma
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      DOI: 10.1158/0008-5472.CAN-21-4313

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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDR2 coordinates EMT and metabolic reprogramming as a shared effector of FOXQ1 and SNAI1
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  121. Jan 2023
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    Enrichment of oral-derived bacteria in inflamed colorectal tumors and distinct associations of Fusobacterium in the mesenchymal subtype
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    Rewiring of hormones and light response pathways underlies the inhibition of stomatal development in an amphibious plant Rorippa aquatica underwater
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  124. academic.oup.com academic.oup.com
    scShapes: a statistical framework for identifying distribution shapes in single-cell RNA-sequencing data
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      DOI: 10.1093/gigascience/giac126

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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors
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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resistance to white spot syndrome virus in the European shore crab is associated with suppressed virion trafficking and heightened immune responses
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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Novel Nucleoside Analogue ProTide NUC-7738 Overcomes Cancer Resistance Mechanisms In Vitro and in a First-In-Human Phase I Clinical Trial
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    Transcriptomic profiling reveals sex-specific molecular signatures of adipose endothelial cells under obesogenic conditions
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    PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry
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    Comparative Genomics Provides Etiologic and Biological Insight into Melanoma Subtypes
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  131. Dec 2022
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    IL-17/CXCL5 signaling within the oligovascular niche mediates human and mouse white matter injury
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness Versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting metabolic adaptations in the breast cancer–liver metastatic niche using dietary approaches to improve endocrine therapy efficacy
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  135. Nov 2022
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    De-erosion of X chromosome dosage compensation by the editing of XIST regulatory regions restores the differentiation potential in hPSCs
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    Systematic single-cell pathway analysis to characterize early T cell activation
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  138. aacrjournals.org aacrjournals.org
    DDR2 Coordinates EMT and Metabolic Reprogramming as a Shared Effector of FOXQ1 and SNAI1
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    aacrjournals.org/cancerrescommun/article/2/11/1388/710518/DDR2-Coordinates-EMT-and-Metabolic-Reprogramming
  139. link.springer.com link.springer.com
    The LncRNA MIAT is identified as a regulator of stemness-associated transcript in glioma
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      DOI: 10.1007/s11033-022-07962-5

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  140. Oct 2022
  141. aacrjournals.org aacrjournals.org
    CircIPO7 Promotes Nasopharyngeal Carcinoma Metastasis and Cisplatin Chemoresistance by Facilitating YBX1 Nuclear Localization
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      DOI: 10.1158/1078-0432.CCR-22-0991

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    aacrjournals.org/clincancerres/article/28/20/4521/709577/CircIPO7-Promotes-Nasopharyngeal-Carcinoma
  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A massively parallel reporter assay reveals focused and broadly encoded RNA localization signals in neurons
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      DOI: 10.1093/nar/gkac806

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  143. www.sciencedirect.com www.sciencedirect.com
    Human-specific regulation of neural maturation identified by cross-primate transcriptomics
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    P2Y6 receptor-mediated signaling amplifies TLR-induced pro-inflammatory responses in microglia
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    Type-I interferon signaling is essential for robust metronomic chemo-immunogenic tumor regression in murine breast cancer
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    NOTCH induced MDSC recruitment after oHSV virotherapy in CNS cancer models modulates anti-tumor immunotherapy
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  148. Sep 2022
  149. f1000research.com f1000research.com
    Circadian signatures of anterior hypothalamus in time-restricted feeding
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    Ral GTPases are critical regulators of spinal cord myelination and homeostasis
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    Combined – whole blood and skin fibroblasts- transcriptomic analysis in Psoriatic Arthritis reveals molecular signatures of activity, resistance and early response to treatment
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    In Vivo Genome-Wide CRISPR Activation Screening Identifies Functionally Important Long Noncoding RNAs in Hepatocellular Carcinoma
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  156. link.springer.com link.springer.com
    Correction to: Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing
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  157. Aug 2022
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    Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors
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    Adrenergic receptor signaling induced by Klf15, a regulator of regeneration enhancer, promotes kidney reconstruction
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    Degradation of GSPT1 causes TP53-independent cell death in leukemia whilst sparing normal hematopoietic stem cells
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    Losartan blocks osteosarcoma-elicited monocyte recruitment, and combined with the kinase inhibitor toceranib, exerts significant clinical benefit in canine metastatic osteosarcoma
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    Gliotransmission of D-serine promotes thirst-directed behaviors in Drosophila
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  165. Jul 2022
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    A chromosome-level genome of the booklouse, Liposcelis brunnea, provides insight into louse evolution and environmental stress adaptation
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    Spatiotemporal genomic analysis reveals distinct molecular features in recurrent stage I non-small cell lung cancers
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    Biogenic action of Lactobacillus plantarum SBT2227 promotes sleep in Drosophila melanogaster
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    Mitochondrial cyclophilin D promotes disease tolerance by licensing NK cell development and IL-22 production against influenza virus
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    Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
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    Dnmt3a knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3
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  174. cellandbioscience.biomedcentral.com cellandbioscience.biomedcentral.com
    Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing
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    EED is required for mouse primordial germ cell differentiation in the embryonic gonad
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    Global-run on sequencing identifies Gm11967 as an Akt-dependent long noncoding RNA involved in insulin sensitivity
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    Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion
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    A Whole Transcriptome Analysis in Peripheral Blood Suggests That Energy Metabolism and Inflammation Are Involved in Major Depressive Disorder
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  179. May 2022
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    Brucella activates the host RIDD pathway to subvert BLOS1-directed immune defense
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  182. aacrjournals.org aacrjournals.org
    Tumor ENPP1(CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer
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  183. Apr 2022
  184. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Type-I Interferon Signaling Is Essential for Robust Metronomic Chemo-Immunogenic Tumor Regression in Murine Breast Cancer
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    HNF4A modulates glucocorticoid action in the liver
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  187. www.nature.com www.nature.com
    TMPRSS2-ERG promotes the initiation of prostate cancer by suppressing oncogene-induced senescence
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    Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease
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  189. aacrjournals.org aacrjournals.org
    FREQUENCY AND GENOMIC ASPECTS OF INTRINSIC RESISTANCE TO VISMODEGIB IN LOCALLY ADVANCED BASAL CELL CARCINOMA
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Presence of H3K4me3 on Paternally Expressed Genes of the Paternal Genome From Sperm to Implantation
    1
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  191. Mar 2022
  192. elifesciences.org elifesciences.org
    Nuclear hormone receptor NHR-49 acts in parallel with HIF-1 to promote hypoxia adaptation in Caenorhabditis elegans
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    Human and mouse trigeminal ganglia cell atlas implicates multiple cell types in migraine
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  194. f1000research.com f1000research.com
    Characterizing gene expression in an&nbsp;<i>in vitro</i> biomechanical strain model of joint health
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  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit
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  196. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
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  197. aacrjournals.org aacrjournals.org
    Race-associated Molecular Changes in Gynecologic Malignancies
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  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective modulation of a pan-essential protein as a therapeutic strategy in cancer
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  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maelstrom functions in the production of Siwi-piRISC capable of regulating transposons in Bombyx germ cells
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    Age-associated decline of MondoA drives cellular senescence through impaired autophagy and mitochondrial homeostasis
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  201. Feb 2022
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    An AIB1 isoform alters enhancer access and enables progression of early stage triple-negative breast cancer
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    Widespread discrepancy in Nnt genotypes and genetic backgrounds complicates granzyme A and other knockout mouse studies
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    SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage
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  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maternal diet-induced obesity during pregnancy alters lipid supply to mouse E18.5 fetuses and changes the cardiac tissue lipidome in a sex-dependent manner
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  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mediator of DNA damage checkpoint 1 (MDC1) is a novel estrogen receptor co-regulator in invasive lobular carcinoma of the breast
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    The ratio of toxic-to-nontoxic microRNAs predicts platinum sensitivity in ovarian cancer
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  208. Jan 2022
  209. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling
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  210. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Estimated Renal Metabolomics at Reperfusion Predicts One-Year Kidney Graft Function
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    Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells
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  212. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulatory T cell transcriptomic reprogramming characterizes adverse events by checkpoint inhibitors in solid tumors
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  213. Dec 2021
  214. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transcriptome analysis reveals the contribution of oligodendrocyte and radial glia-derived cues for maintenance of microglia identity
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  215. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effect of miR-183-5p on Cholestatic Liver Fibrosis by Regulating Fork Head Box Protein O1 Expression
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    Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential
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  217. Nov 2021
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    Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring
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    Attention to time-of-day variability improves the reproducibility of gene expression patterns in multiple sclerosis
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    Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia
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    Patch-seq of mouse DRG neurons reveals candidate genes for specific mechanosensory functions
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    Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription
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  223. Oct 2021
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    Acrylamide modulates the mouse epididymal proteome to drive alterations in the sperm small non-coding RNA profile and dysregulate embryo development
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  225. Sep 2021
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    Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
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    Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave
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  228. Aug 2021
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    Pro-inflammatory β cell small extracellular vesicles induce β cell failure through activation of the CXCL10/CXCR3 axis in diabetes
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    Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria
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    SAGE Journals: Your gateway to world-class research journals
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    The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes
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    Evolution of reduced co-activator dependence led to target expansion of a starvation response pathway
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