119 Matching Annotations
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    Patient-derived organoids from metastatic colorectal cancer mirror tumor heterogeneity and predict patient survival and drug sensitivity
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    sciencedirect.com/science/article/pii/S2666379126002570
  3. May 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for identifying genetic modifiers of phenotypes in individuals with disease-associated variants
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    pmc.ncbi.nlm.nih.gov/articles/PMC13188092/
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    The molecular and functional landscape of resistance to FOLFIRI chemotherapy in metastatic colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12877753/
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    Intra-tumoral tertiary lymphoid structures characterized by a B cell-related signature elicit antitumor effect through HAPLN3 in hepatocellular carcinoma
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    aacrjournals.org/cancerimmunolres/article/14/5/771/784463/Intratumoral-Tertiary-Lymphoid-Structures
  7. Apr 2026
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    Somatic cancer variants enriched in Alzheimer’s disease microglia-like cells drive inflammatory and proliferative states
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    sciencedirect.com/science/article/pii/S0092867426003417
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    Patient-derived pediatric brain tumor orthotopic xenografts and tumor organoids faithfully recapitulate primary tumors
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    science.org/doi/10.1126/sciadv.aea4966
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    Mapping genomic heterogeneity in paediatric and adolescent-young adult sarcomas: insights from the Italian SAR-GEN2016 and SAR-GEN_ITA prospective multicenter trials
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    pmc.ncbi.nlm.nih.gov/articles/PMC13090861/
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    Preclinical Combination Targeting VEGF and PI3K in a Rare, Aggressive Mixed Endometrial Carcinoma: An Applied Case Report
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    pmc.ncbi.nlm.nih.gov/articles/PMC13081119/
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    Clinicogenomic Characterization of Primary Sclerosing Cholangitis-Associated Biliary Tract Cancers
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    aacrjournals.org/clincancerres/article/32/2/363/771741/Clinicogenomic-Characterization-of-Primary
  13. Mar 2026
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    Long-term outcomes by clinical and molecular risk stratification in patients with medulloblastoma receiving risk-adapted therapy
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    sciencedirect.com/science/article/pii/S2666634026000796
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    Gain of Chromosome 1q and MYCN Characterize Unique Subgroups of Asian Wilms Tumor Patients
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    sciencedirect.com/science/article/pii/S2468294226001024
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    Metabolite-induced DNA damage drives stochastic stem cell loss and clonal hematopoiesis
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    Ex Vivo Immuno-Oncology Platform Reveals Spatial T Cell Infiltration Patterns Linked to ATR Inhibition Responses in High-Grade Serous Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618831/
  18. Feb 2026
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    Endogenous retrovirus-derived RNA-DNA hybrids induce microglial synaptic pruning in autism models
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    sciencedirect.com/science/article/pii/S0896627326000127
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    Systematic functional drug testing in patient-derived models reveals ex vivo sensitivities associated with clinical outcome in rare solid tumors
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    biorxiv.org/content/10.64898/2026.02.18.705724v1
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    Biomimetic hydrogel for the construction of patient-derived bladder cancer organoids with aggressive growth
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  22. Jan 2026
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Assessment of Circulating Tumor DNA for Early Detection of Hepatocellular Carcinoma in Alpha‐Fetoprotein–Negative Patients With Cirrhotic Nodules
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    pmc.ncbi.nlm.nih.gov/articles/PMC12748524/
  24. Dec 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Radiogenomic Profiling of Prostate Tumors prior to External Beam Radiotherapy Converges on a Transcriptomic Signature of TGF-β Activity Driving Tumor Recurrence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12703358/
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    Personalized ctDNA detection and genomic profiling in the NeoRHEA Study
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    Extrachromosomal circular miRNA-gene amplifications contribute to the renal cancer phenotype
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    A Proteogenomic View of Synchronous Endometrioid Endometrial and Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12203618/
  29. Nov 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12569591/
  31. Sep 2025
  32. pathsocjournals.onlinelibrary.wiley.com pathsocjournals.onlinelibrary.wiley.com
    Tracing metastatic spread in pediatric solid tumors using copy number and targeted deep sequencing
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    ctDNA detects residual disease after neoadjuvant chemoradiotherapy and guides adjuvant therapy in esophageal squamous cell carcinoma
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  34. Aug 2025
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    Cyclin-dependent kinase 9 inhibitors as oncogene signaling modulators in combination with targeted therapy for the treatment of colorectal cancer
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    biorxiv.org/content/10.1101/2025.08.13.669992v1
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    Genomic Signatures of Poor Prognosis in Merkel Cell Carcinoma: A Single-Institution Prospective Study
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    Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations
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  38. Jul 2025
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    Bi-allelic mutations in KCTD11 cause a new form of autosomal recessive intermediate Charcot-Marie-Tooth disease
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    Microhomology-Mediated End Joining as a Novel Mechanism Underlying Androgen Insensitivity Syndrome
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  41. Jun 2025
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SpatialSNV: A novel method for identifying and analyzing spatially resolved SNVs in tumor microenvironments
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    Spatial–Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune Microenvironment
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  44. May 2025
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    Immunohistochemical and molecular evolutionary features of jejunoileal adenocarcinoma unveiled through comparative analysis with colorectal adenocarcinoma
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    Telomere-to-telomere genome of common bean (Phaseolus vulgaris L., YP4)
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    dx.doi.org/10.1093/gigascience/giaf001
  47. Apr 2025
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    PLK1 Inhibition Induces Synthetic Lethality in Fanconi Anemia Pathway–Deficient Acute Myeloid Leukemia
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    Metabolite-dependent m6A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration
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    Germline Pathogenic DROSHA Variants Are Linked to Pineoblastoma and Wilms Tumor Predisposition
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    pmc.ncbi.nlm.nih.gov/articles/PMC11995001/
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    Germline variants in patients from the Iranian hereditary colorectal cancer registry
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  53. Mar 2025
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    mTOR-mediated p62/SQSTM1 stabilization confers a robust survival mechanism for ovarian cancer
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    Enhancing inbreeding estimation and global conservation insights through chromosome-level assemblies of the Chinese and Malayan pangolin
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    pmc.ncbi.nlm.nih.gov/articles/PMC11825179/
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    DNA methylation profiling identifies subgroups of lung adenocarcinoma with distinct immune cell composition, DNA methylation age, and clinical outcome
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    Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy
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  61. Dec 2024
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inference of Genetic Diversity, Population Structure, and Selection Signatures in Xiangxi White Buffalo of China Through Whole-Genome Resequencing
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    Modeling Drug Responses and Evolutionary Dynamics using Patient-Derived Xenografts Reveals Precision Medicine Strategies for Triple Negative Breast Cancer
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    Construction and analysis of telomere-to-telomere genomes for 2 sweet oranges: Longhuihong and Newhall (Citrus sinensis)
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    Growth-dependent concentration gradient of the oscillating Min system in Escherichia coli
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    Development and validation of the utLIFE-PC algorithm for noninvasive detection of prostate cancer in urine: A prospective, observational study
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  67. Nov 2024
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  69. Oct 2024
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radiosensitizing Effect of PARP Inhibition on Chondrosarcoma and Chondrocyte Cells Is Dependent on Radiation LET
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  71. Sep 2024
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    Whole-genome sequencing of the invasive golden apple snail Pomacea canaliculata from Asia reveals rapid expansion and adaptive evolution
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    The Proteogenomics of Prostate Cancer Radioresistance
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    Telomere-to-telomere gap-free genome assembly of the endangered Yangtze finless porpoise and East Asian finless porpoise
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    Shared cancer dataset analysis identifies and predicts the quantitative effects of pan-cancer somatic driver variants
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    Inhibition of Aberrantly Overexpressed Polo-like Kinase 4 Is a Potential Effective Treatment for DNA Damage Repair–Deficient Uterine Leiomyosarcoma
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  77. Aug 2024
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  80. Jul 2024
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    Further evidence from DNAH12 supports favorable fertility outcomes of infertile males with dynein axonemal heavy chain gene family variants
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  82. May 2024
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    Integrative molecular analyses of the MD Anderson prostate cancer patient-derived xenograft (MDA PCa PDX) series
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    Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma
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  85. Mar 2024
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel type of monocytic leukemia stem cell revealed by the clinical use of venetoclax-based therapy
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  87. Jan 2024
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    Genetic variants affecting NQO1 protein levels impact the efficacy of idebenone treatment in Leber hereditary optic neuropathy
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    Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease
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  90. Dec 2023
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    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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    Managing genomic diversity in conservation programs of Chinese domestic chickens
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    Single-cell reconstruction and mutation enrichment analysis identifies dysregulated cardiomyocyte and endothelial cells in congenital heart disease
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  95. Oct 2023
  96. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Immune checkpoint inhibitor-related molecular markers predict prognosis in extrahepatic cholangiocarcinoma
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    onlinelibrary.wiley.com/doi/10.1002/cam4.6441
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    Individualized tumor-informed circulating tumor DNA analysis for postoperative monitoring of non-small cell lung cancer
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  98. Aug 2023
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    Molecular and clonal evolution in vivo reveal a common pathway of distant relapse gliomas
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    Early clonal extinction in glioblastoma progression revealed by genetic barcoding
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical features associated with outcomes and biomarker analysis of dabrafenib plus trametinib treatment in patients with BRAF-mutant melanoma brain metastases
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    ncbi.nlm.nih.gov/pmc/articles/PMC9898142/
  102. Jun 2023
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids
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  104. Mar 2023
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    Nicotinamide riboside supplementation is not associated with altered methylation homeostasis in Parkinson’s disease
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The first Antechinus reference genome provides a resource for investigating the genetic basis of semelparity and age-related neuropathologies
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    ncbi.nlm.nih.gov/pmc/articles/PMC9631953/
  107. Feb 2023
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive genomic profiling of upper tract urothelial carcinoma and urothelial carcinoma of the bladder identifies distinct molecular characterizations with potential implications for targeted therapy & immunotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC9936149/
  109. Jan 2023
  110. www.nature.com www.nature.com
    Germline rare deleterious variant load alters cancer risk, age of onset and tumor characteristics
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    nature.com/articles/s41698-023-00354-3
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Phase II Trial of the Bruton Tyrosine-Kinase Inhibitor Zanubrutinib (BGB-3111) in Patients with Relapsed/Refractory Waldenström Macroglobulinemia
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  112. Dec 2022
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    Protocol to analyze population structure and migration history based on human genome variation data
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  115. Sep 2022
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic Diversity and Selective Signature in Dabieshan Cattle Revealed by Whole-Genome Resequencing
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  122. May 2022
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  126. Apr 2022
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  130. Mar 2022
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  134. Jan 2022
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  136. Aug 2021
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  144. Apr 2021
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  146. Feb 2021
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  148. Jan 2021
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  150. Oct 2020
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  152. Sep 2020
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  155. Jan 2020
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  159. Nov 2018
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  170. Nov 2017
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