118 Matching Annotations
  1. Last 7 days
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    Stimulation of Adult Muscle Stem Cells with BMPs Results in Direct Activation of Notch Pathway Genes
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    pmc.ncbi.nlm.nih.gov/articles/PMC13511064/
  3. Jul 2026
  4. aacrjournals.org aacrjournals.org
    TRAPPC4 Promotes GPX4 Stability to Drive Ferroptosis Resistance and Tumor Progression in Head and Neck Squamous Cell Carcinoma
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    aacrjournals.org/cancerres/article/86/14/3436/786573/TRAPPC4-Promotes-GPX4-Stability-to-Drive
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    ZNF296 Drives Immune Evasion in Epithelial Cancers by Repressing Immune Stimulatory Genes
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    aacrjournals.org/cancerres/article/86/1/116/771155/ZNF296-Drives-Immune-Evasion-in-Epithelial-Cancers
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    Loss of SETD8 Impairs Mitochondrial Homeostasis to Suppress Leukemia Stem Cell Function in t(8;21) Acute Myeloid Leukemia
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    aacrjournals.org/cancerres/article/85/21/4122/766740/Loss-of-SETD8-Impairs-Mitochondrial-Homeostasis-to
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    SWI/SNF Functions as a Gatekeeper of Enhancer Chromatin Access to Control Progression of Mesenchymal Triple-Negative Breast Cancer
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    aacrjournals.org/cancerres/article/85/23/4648/767290/SWI-SNF-Functions-as-a-Gatekeeper-of-Enhancer
  8. Jun 2026
  9. aacrjournals.org aacrjournals.org
    DPY30 is an epigenetic decoupler linking replication stress to immunoediting in pancreatic cancer
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    aacrjournals.org/cancerres/article/86/12/2837/785625/DPY30-Is-an-Epigenetic-Decoupler-Linking
  10. Apr 2026
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    Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin
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    sciencedirect.com/science/article/pii/S1931312826001319
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    The chromatin remodeller CHD4 regulates transcription factor binding to both prevent activation of silent enhancers and maintain active regulatory elements
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    pmc.ncbi.nlm.nih.gov/articles/PMC12867480/
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    Functional genetic screens reveal key pathways instructing the molecular phenotypes of tumor-associated macrophages
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    aacrjournals.org/cancerimmunolres/article/13/12/2054/768330/Functional-Genetic-Screens-Reveal-Key-Pathways
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    Loss of Ehmt2/G9a function in zebrafish is associated with global deficiency in H3K9 dimethylation, misregulated cell cycle dynamics, and embryonic developmental delay
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    biorxiv.org/content/10.64898/2026.04.05.716391v1
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    Epigenetic context defines the transcriptional activity of canonical and noncanonical NF-κB signaling in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13039881/
  16. Mar 2026
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    Condensation of an H3K9me3 methyltransferase complex promotes heritable gene silencing and heterochromatin formation
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    sciencedirect.com/science/article/pii/S2211124726002305
  18. Feb 2026
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    Cytoplasmic mRNA decay by the antiviral nuclease RNase L promotes transcriptional repression
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    sciencedirect.com/science/article/pii/S2211124726001063
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    Cell-free DNA epigenomic profiling enables noninvasive detection and monitoring of translocation renal cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12867156/
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    C9orf72 hexanucleotide repeat RNA drives transcriptional dysregulation through genome-wide DNA:RNA hybrid G-quadruplexes
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    sciencedirect.com/science/article/pii/S0896627325009328
  22. Dec 2025
  23. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    From degraded to deciphered: Applying ATAC-seq to forensic molecular diagnosis under degradation conditions
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    sciencedirect.com:5037/science/article/pii/S0379073825004335
  24. Nov 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HIF-2-dependent Regulation of PTHrP and Paraneoplastic Hypercalcemia in Aggressive Clear Cell Renal Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12642454/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12616242/
  27. Oct 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12493205/
  29. Sep 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Requirements for establishment and epigenetic stability of mammalian heterochromatin
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    Detection and monitoring of translocation renal cell carcinoma via plasma cell-free epigenomic profiling
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    biorxiv.org/content/10.1101/2025.08.31.673338v1
  32. Aug 2025
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    Genetic and Epigenetic Reprogramming of Transposable Elements Drives ecDNA-Mediated Metastatic Prostate Cancer
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    biorxiv.org/content/10.1101/2025.08.08.668693v1
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    Interplay of YEATS2 and GCDH regulates histone crotonylation and drives EMT in head and neck cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12352869/
  35. Jul 2025
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    β-catenin functions as a molecular adapter for disordered cBAF interactions
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    Multiomics uncovers the epigenomic and transcriptomic response to viral and bacterial stimulation in turbot
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    The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
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    sciencedirect.com/science/article/pii/S1074761325002481
  40. Jun 2025
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    C-terminal binding protein 2 interacts with JUNB to control macrophage inflammation
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  44. Mar 2025
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    Orchestration of pluripotent stem cell genome reactivation during mitotic exit
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    Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus
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    pmc.ncbi.nlm.nih.gov/articles/PMC11928027/
  47. Feb 2025
  48. aacrjournals.org aacrjournals.org
    Epigenome reprogramming through H3K27 and H3K4 trimethylation as a resistance mechanism to DNA methylation inhibition in BRAFV600E-mutated colorectal cancer
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    aacrjournals.org/clincancerres/article/30/22/5166/749574/Epigenome-Reprogramming-Through-H3K27-and-H3K4
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    Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte progenitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11318668/
  50. Jan 2025
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    KDM6B-dependent epigenetic programming of uterine fibroblasts in early pregnancy regulates parturition timing in mice
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  52. Dec 2024
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BPDCN MYB fusions regulate cell cycle genes, impair differentiation, and induce myeloid–dendritic cell leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11665559/
  54. Nov 2024
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Astrocyte allocation during brain development is controlled by Tcf4-mediated fate restriction
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  56. Oct 2024
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    Monocytic Differentiation and AHR Signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
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    aacrjournals.org/bloodcancerdiscov/article/2/5/518/665838/Monocytic-Differentiation-and-AHR-Signaling-as
  58. Jul 2024
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    The primitive endoderm supports lineage plasticity to enable regulative development
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    ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma
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  61. Jun 2024
  62. molecular-cancer.biomedcentral.com molecular-cancer.biomedcentral.com
    Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients
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    molecular-cancer.biomedcentral.com/articles/10.1186/s12943-024-02034-7
  63. May 2024
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    Reciprocal conversion between annual and polycarpic perennial flowering behavior in the Brassicaceae
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    Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11104289/
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    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
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    sciencedirect.com/science/article/pii/S0092867424004483
  67. Apr 2024
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    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
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    A senescence restriction point acting on chromatin integrates oncogenic signals
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  70. Mar 2024
  71. link.springer.com link.springer.com
    From degraded to deciphered: ATAC-seq’s application potential in forensic diagnosis
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    link.springer.com/article/10.1007/s00414-024-03206-2
  72. Feb 2024
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10527051/
  74. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-023-03161-y
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    PHF6 suppresses self-renewal of leukemic stem cells in AML
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802281/
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    PUF partner interactions at a conserved interface shape the RNA-binding landscape and cell fate in Caenorhabditis elegans
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    ncbi.nlm.nih.gov/pmc/articles/PMC11253550/
  77. Jan 2024
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
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    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
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    Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10794847/
  81. Dec 2023
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    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blimp-1 and c-Maf regulate  Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10709690/
  84. Nov 2023
  85. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
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    nature.com/articles/s41388-023-02892-3
  86. wellcomeopenresearch.org wellcomeopenresearch.org
    Blimp-1 and c-Maf regulate Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
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    wellcomeopenresearch.org/articles/8-403/v1
  87. Jun 2023
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    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
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    aacrjournals.org/cancerdiscovery/article/13/6/1478/726967/R-2-Hydroxyglutarate-Inhibits-KDM5-Histone-Lysine
  90. May 2023
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  92. Apr 2023
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    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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    Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia
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    sciencedirect.com/science/article/pii/S2211124723003844
  95. Aug 2022
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    The sage genome provides insight into the evolutionary dynamics of diterpene biosynthesis gene cluster in plants
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    sciencedirect.com/science/article/pii/S2211124722010531
  97. aacrjournals.org aacrjournals.org
    Developmental pathways are epigenetically reprogrammed during lung cancer brain metastasis
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    aacrjournals.org/cancerres/article/82/15/2692/707331/Developmental-Pathways-Are-Epigenetically
  98. Jun 2022
  99. elifesciences.org elifesciences.org
    Dnmt3a knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3
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    elifesciences.org/articles/66909
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    JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation
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  101. Mar 2022
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit
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    ncbi.nlm.nih.gov/pmc/articles/PMC8903835/
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A test of the pioneer factor hypothesis using ectopic liver gene activation
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  104. Jan 2022
  105. www.sciencedirect.com www.sciencedirect.com
    Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration
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  106. Nov 2021
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An epigenetic mechanism underlying chromosome 17p deletion-driven tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8591992/
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    Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis
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    Identification of a novel FUS/ETV4 fusion and comparative analysis with other Ewing sarcoma fusion proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC8568690/
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    Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones
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    Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription
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    sciencedirect.com/science/article/pii/S2211124721014169
  112. Oct 2021
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    PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
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  114. Sep 2021
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8462123/
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    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
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    SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape
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  118. Aug 2021
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC7401316/
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    Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding
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