102 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HIF-2-dependent Regulation of PTHrP and Paraneoplastic Hypercalcemia in Aggressive Clear Cell Renal Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12642454/
  3. Nov 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12616242/
  5. Oct 2025
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    CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12493205/
  7. Sep 2025
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    Requirements for establishment and epigenetic stability of mammalian heterochromatin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12478525/
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    Detection and monitoring of translocation renal cell carcinoma via plasma cell-free epigenomic profiling
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    biorxiv.org/content/10.1101/2025.08.31.673338v1
  10. Aug 2025
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    Genetic and Epigenetic Reprogramming of Transposable Elements Drives ecDNA-Mediated Metastatic Prostate Cancer
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    biorxiv.org/content/10.1101/2025.08.08.668693v1
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    Interplay of YEATS2 and GCDH regulates histone crotonylation and drives EMT in head and neck cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12352869/
  13. Jul 2025
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    β-catenin functions as a molecular adapter for disordered cBAF interactions
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    sciencedirect.com/science/article/pii/S1097276525005763
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    Multiomics uncovers the epigenomic and transcriptomic response to viral and bacterial stimulation in turbot
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    The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
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    sciencedirect.com/science/article/pii/S1074761325002481
  18. Jun 2025
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    C-terminal binding protein 2 interacts with JUNB to control macrophage inflammation
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  22. Mar 2025
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    Orchestration of pluripotent stem cell genome reactivation during mitotic exit
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    Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus
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  25. Feb 2025
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    Epigenome reprogramming through H3K27 and H3K4 trimethylation as a resistance mechanism to DNA methylation inhibition in BRAFV600E-mutated colorectal cancer
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    aacrjournals.org/clincancerres/article/30/22/5166/749574/Epigenome-Reprogramming-Through-H3K27-and-H3K4
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    Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte progenitors
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  28. Jan 2025
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    KDM6B-dependent epigenetic programming of uterine fibroblasts in early pregnancy regulates parturition timing in mice
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  30. Dec 2024
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    BPDCN MYB fusions regulate cell cycle genes, impair differentiation, and induce myeloid–dendritic cell leukemia
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  32. Nov 2024
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    Astrocyte allocation during brain development is controlled by Tcf4-mediated fate restriction
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  34. Oct 2024
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    Monocytic Differentiation and AHR Signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
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  36. Jul 2024
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    The primitive endoderm supports lineage plasticity to enable regulative development
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    ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma
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  39. Jun 2024
  40. molecular-cancer.biomedcentral.com molecular-cancer.biomedcentral.com
    Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients
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  41. May 2024
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    Reciprocal conversion between annual and polycarpic perennial flowering behavior in the Brassicaceae
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    Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer
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    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
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  45. Apr 2024
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    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
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    A senescence restriction point acting on chromatin integrates oncogenic signals
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  48. Mar 2024
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    From degraded to deciphered: ATAC-seq’s application potential in forensic diagnosis
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  50. Feb 2024
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    The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10527051/
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    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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    PHF6 suppresses self-renewal of leukemic stem cells in AML
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    PUF partner interactions at a conserved interface shape the RNA-binding landscape and cell fate in Caenorhabditis elegans
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  55. Jan 2024
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    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
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    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
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    Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation
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  59. Dec 2023
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    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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    Blimp-1 and c-Maf regulate  Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
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  62. Nov 2023
  63. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
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    nature.com/articles/s41388-023-02892-3
  64. wellcomeopenresearch.org wellcomeopenresearch.org
    Blimp-1 and c-Maf regulate Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
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    wellcomeopenresearch.org/articles/8-403/v1
  65. Jun 2023
  66. 52.53.155.43 52.53.155.43
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    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
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  68. May 2023
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  70. Apr 2023
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    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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    Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia
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  73. Aug 2022
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    The sage genome provides insight into the evolutionary dynamics of diterpene biosynthesis gene cluster in plants
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    Developmental pathways are epigenetically reprogrammed during lung cancer brain metastasis
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    aacrjournals.org/cancerres/article/82/15/2692/707331/Developmental-Pathways-Are-Epigenetically
  76. Jun 2022
  77. elifesciences.org elifesciences.org
    Dnmt3a knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3
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    JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation
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  79. Mar 2022
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    Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit
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    A test of the pioneer factor hypothesis using ectopic liver gene activation
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  82. Jan 2022
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    Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration
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  84. Nov 2021
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    An epigenetic mechanism underlying chromosome 17p deletion-driven tumorigenesis
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    Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis
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    Identification of a novel FUS/ETV4 fusion and comparative analysis with other Ewing sarcoma fusion proteins
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    Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones
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    Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription
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  90. Oct 2021
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    PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
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  92. Sep 2021
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    Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
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    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
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    SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape
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  96. Aug 2021
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia
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    Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding
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    The polycomb proteins EZH1 and EZH2 co-regulate chromatin accessibility and nephron progenitor cell lifespan in mice
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  102. Jul 2021
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    Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphoma
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    Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors
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    N6-methyladenine DNA Modification in Glioblastoma
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  106. May 2021
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    Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function
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    Chromatin Accessibility Dynamics and a Hierarchical Transcriptional Regulatory Network Structure for Plant Somatic Embryogenesis
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  109. Apr 2021
  110. www.cell.com www.cell.com
    IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
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    cell.com/cancer-cell/fulltext/S1535-6108(20)30311-1
  111. Feb 2021
  112. elifesciences.org elifesciences.org
    Beta-catenin signaling regulates barrier-specific gene expression in circumventricular organ and ocular vasculatures
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    elifesciences.org/articles/43257
  113. Jan 2021
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    Protocol for assaying chromatin accessibility using ATAC-seq in plants
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    sciencedirect.com/science/article/pii/S2666166720302768
  115. Sep 2020
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of zebrafish periderm enhancers facilitates identification of a regulatory variant near human KRT8/18
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    ncbi.nlm.nih.gov/pmc/articles/PMC7039683/
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    PHF19 mediated regulation of proliferation and invasiveness in prostate cancer cells
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    Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage
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    A genome-wide view of the de-differentiation of central nervous system endothelial cells in culture
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    Genomic Rewiring of SOX2 Chromatin Interaction Network during Differentiation of ESCs to Postmitotic Neurons
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  121. Jan 2020
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    RNA Interactions Are Essential for CTCF-Mediated Genome Organization
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    Quantification of Differential Transcription Factor Activity and Multiomics-Based Classification into Activators and Repressors: diffTF
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    Genome-wide Analyses of Chromatin State in Human Mast Cells Reveal Molecular Drivers and Mediators of Allergic and Inflammatory Diseases
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