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Aug 2025
www.biorxiv.org www.biorxiv.org

Genetic and Epigenetic Reprogramming of Transposable Elements Drives ecDNA-Mediated Metastatic Prostate Cancer

1
1. scibot 20 Aug 2025
  
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  DOI: 10.1101/2025.08.08.668693
  
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biorxiv.org/content/10.1101/2025.08.08.668693v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Interplay of YEATS2 and GCDH regulates histone crotonylation and drives EMT in head and neck cancer

1
1. scibot 16 Aug 2025
  
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  DOI: 10.7554/eLife.103321
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12352869/
Jul 2025
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β-catenin functions as a molecular adapter for disordered cBAF interactions

1
1. scibot 22 Jul 2025
  
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  DOI: 10.1016/j.molcel.2025.06.026
  
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sciencedirect.com/science/article/pii/S1097276525005763
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Multiomics uncovers the epigenomic and transcriptomic response to viral and bacterial stimulation in turbot

1
1. scibot 17 Jul 2025
  
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  DOI: 10.1093/gigascience/giaf077
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12263217/
52.53.155.43 52.53.155.43

1-s2.0-S0016508525057324-main-html.html

1
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  DOI: 10.1053/j.gastro.2025.07.003
  
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52.53.155.43/a363e4ae90be5a0c17cae72bbc9ca19379f34011/1-s2.0-S0016508525057324-main-html.html
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The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells

1
1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.001
  
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sciencedirect.com/science/article/pii/S1074761325002481
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

C-terminal binding protein 2 interacts with JUNB to control macrophage inflammation

1
1. scibot 25 Jun 2025
  
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  DOI: 10.26508/lsa.202503263
  
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52.53.155.43 52.53.155.43

PDF-html.html

2
1. scibot 13 Jun 2025
  
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  DOI: 10.1158/2159-8290.cd-24-1033
  
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2. scibot 12 Jun 2025
  
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  DOI: 10.1158/2159-8290.cd-24-1033
  
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52.53.155.43/a7ee3b12d468dfb2dd9f5d25a6280eb2adf38466/PDF-html.html
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1-s2.0-S2589004225011162-main-html.html

1
1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112855
  
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52.53.155.43/aade76b5737bfade2462ebc8caccc014a630e1a8/1-s2.0-S2589004225011162-main-html.html
Mar 2025
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Orchestration of pluripotent stem cell genome reactivation during mitotic exit

1
1. scibot 28 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115486
  
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sciencedirect.com/science/article/pii/S2211124725002578
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus

1
1. scibot 27 Mar 2025
  
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  DOI: 10.7554/eLife.102019
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11928027/
Feb 2025
aacrjournals.org aacrjournals.org

Epigenome reprogramming through H3K27 and H3K4 trimethylation as a resistance mechanism to DNA methylation inhibition in BRAFV600E-mutated colorectal cancer

1
1. scibot 13 Feb 2025
  
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  DOI: 10.1158/1078-0432.CCR-24-1166
  
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aacrjournals.org/clincancerres/article/30/22/5166/749574/Epigenome-Reprogramming-Through-H3K27-and-H3K4
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte progenitors

1
1. scibot 13 Feb 2025
  
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  DOI: 10.1083/jcb.202308064
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11318668/
Jan 2025
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KDM6B-dependent epigenetic programming of uterine fibroblasts in early pregnancy regulates parturition timing in mice

1
1. scibot 23 Jan 2025
  
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  DOI: 10.1016/j.cell.2024.12.019
  
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sciencedirect.com/science/article/pii/S0092867424014326
Dec 2024
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BPDCN MYB fusions regulate cell cycle genes, impair differentiation, and induce myeloid–dendritic cell leukemia

1
1. scibot 27 Dec 2024
  
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  DOI: 10.1172/jci.insight.183889
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11665559/
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Astrocyte allocation during brain development is controlled by Tcf4-mediated fate restriction

1
1. scibot 08 Nov 2024
  
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  DOI: 10.1038/s44318-024-00218-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11535398/
Oct 2024
aacrjournals.org aacrjournals.org

Monocytic Differentiation and AHR Signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia

1
1. scibot 02 Oct 2024
  
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  DOI: 10.1158/2643-3230.BCD-21-0012
  
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aacrjournals.org/bloodcancerdiscov/article/2/5/518/665838/Monocytic-Differentiation-and-AHR-Signaling-as
Jul 2024
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The primitive endoderm supports lineage plasticity to enable regulative development

1
1. scibot 24 Jul 2024
  
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  DOI: 10.1016/j.cell.2024.05.051
  
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sciencedirect.com/science/article/pii/S0092867424005956
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ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma

1
1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114406
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11290356/
Jun 2024
molecular-cancer.biomedcentral.com molecular-cancer.biomedcentral.com

Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients

1
1. scibot 06 Jun 2024
  
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  DOI: 10.1186/s12943-024-02034-7
  
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molecular-cancer.biomedcentral.com/articles/10.1186/s12943-024-02034-7
May 2024
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Reciprocal conversion between annual and polycarpic perennial flowering behavior in the Brassicaceae

3
1. scibot 30 May 2024
  
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  DOI: 10.1016/j.cell.2024.04.047
  
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  DOI: 10.1016/j.cell.2024.04.047
  
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sciencedirect.com/science/article/pii/S0092867424004732
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Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer

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1. scibot 22 May 2024
  
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  DOI: 10.1158/2767-9764.CRC-23-0639
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11104289/
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Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor

2
1. scibot 14 May 2024
  
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  DOI: 10.1016/j.cell.2024.04.023
  
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2. scibot 14 May 2024
  
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  DOI: 10.1016/j.cell.2024.04.023
  
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sciencedirect.com/science/article/pii/S0092867424004483
Apr 2024
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Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway

1
1. scibot 05 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114065
  
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sciencedirect.com/science/article/pii/S2211124724003930
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A senescence restriction point acting on chromatin integrates oncogenic signals

1
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  DOI: 10.1016/j.celrep.2024.114044
  
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sciencedirect.com/science/article/pii/S2211124724003723
Mar 2024
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From degraded to deciphered: ATAC-seq’s application potential in forensic diagnosis

1
1. scibot 19 Mar 2024
  
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  DOI: 10.1007/s00414-024-03206-2
  
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link.springer.com/article/10.1007/s00414-024-03206-2
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer

1
1. scibot 16 Feb 2024
  
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  DOI: 10.1158/0008-5472.CAN-23-0539
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10527051/
genomebiology.biomedcentral.com genomebiology.biomedcentral.com

The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer

1
1. scibot 07 Feb 2024
  
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  DOI: 10.1186/s13059-023-03161-y
  
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genomebiology.biomedcentral.com/articles/10.1186/s13059-023-03161-y
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PHF6 suppresses self-renewal of leukemic stem cells in AML

1
1. scibot 02 Feb 2024
  
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  DOI: 10.1101/2024.01.06.573649
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10802281/
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PUF partner interactions at a conserved interface shape the RNA-binding landscape and cell fate in Caenorhabditis elegans

1
1. scibot 02 Feb 2024
  
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  DOI: 10.1016/j.devcel.2024.01.005
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11253550/
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer

1
1. scibot 10 Jan 2024
  
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  DOI: 10.1158/0008-5472.CAN-22-2712
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10330305/
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Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation

1
1. scibot 06 Jan 2024
  
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  DOI: 10.1016/j.cmet.2023.12.010
  
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sciencedirect.com/science/article/pii/S1550413123004618
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Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation

1
1. scibot 06 Jan 2024
  
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  DOI: 10.1016/j.xgen.2023.100471
  
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Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma

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Blimp-1 and c-Maf regulate Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells

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Selective inhibition of CDK9 in triple negative breast cancer

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Blimp-1 and c-Maf regulate Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells

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can-22-2712-html.html

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(R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers

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May 2023
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bqad083-html.html

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A hyper-quiescent chromatin state formed during aging is reversed by regeneration

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Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia

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The sage genome provides insight into the evolutionary dynamics of diterpene biosynthesis gene cluster in plants

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Developmental pathways are epigenetically reprogrammed during lung cancer brain metastasis

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Dnmt3a knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3

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JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation

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Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit

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A test of the pioneer factor hypothesis using ectopic liver gene activation

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Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration

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An epigenetic mechanism underlying chromosome 17p deletion-driven tumorigenesis

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Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis

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Identification of a novel FUS/ETV4 fusion and comparative analysis with other Ewing sarcoma fusion proteins

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Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones

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Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription

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PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation

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Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia

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H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity

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SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape

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Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia

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Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding

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The polycomb proteins EZH1 and EZH2 co-regulate chromatin accessibility and nephron progenitor cell lifespan in mice

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Untitled document

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Untitled document

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Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphoma

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Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors

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N6-methyladenine DNA Modification in Glioblastoma

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Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function

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Chromatin Accessibility Dynamics and a Hierarchical Transcriptional Regulatory Network Structure for Plant Somatic Embryogenesis

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IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis

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  DOI: 10.1016/j.ccell.2020.06.007
  
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cell.com/cancer-cell/fulltext/S1535-6108(20)30311-1
Feb 2021
elifesciences.org elifesciences.org

Beta-catenin signaling regulates barrier-specific gene expression in circumventricular organ and ocular vasculatures

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1. scibot 26 Feb 2021
  
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  DOI: 10.7554/eLife.43257
  
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Jan 2021
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Protocol for assaying chromatin accessibility using ATAC-seq in plants

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1. scibot 26 Jan 2021
  
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  RRID:SCR_012918
  
  DOI: 10.1016/j.xpro.2020.100289
  
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sciencedirect.com/science/article/pii/S2666166720302768
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Analysis of zebrafish periderm enhancers facilitates identification of a regulatory variant near human KRT8/18

1
1. scibot 26 Sep 2020
  
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  RRID:SCR_012918
  
  DOI: 10.7554/eLife.51325
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7039683/
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PHF19 mediated regulation of proliferation and invasiveness in prostate cancer cells

1
1. scibot 17 Sep 2020
  
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  DOI: 10.7554/eLife.51373
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7064337/
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Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage

1
1. scibot 16 Sep 2020
  
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  RRID:SCR_012918
  
  DOI: 10.1016/j.cell.2020.03.052
  
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sciencedirect.com/science/article/pii/S0092867420303457
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A genome-wide view of the de-differentiation of central nervous system endothelial cells in culture

1
1. scibot 16 Sep 2020
  
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  RRID:SCR_012918
  
  DOI: 10.7554/eLife.51276
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6948952/
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Genomic Rewiring of SOX2 Chromatin Interaction Network during Differentiation of ESCs to Postmitotic Neurons

1
1. scibot 14 Sep 2020
  
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  RRID:SCR_012918
  
  DOI: 10.1016/j.cels.2020.05.003
  
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sciencedirect.com/science/article/pii/S2405471220301885
Jan 2020
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RNA Interactions Are Essential for CTCF-Mediated Genome Organization

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_012918
  
  DOI: 10.1016/j.molcel.2019.08.015
  
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sciencedirect.com/science/article/pii/S1097276519306549
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Quantification of Differential Transcription Factor Activity and Multiomics-Based Classification into Activators and Repressors: diffTF

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_012918
  
  DOI: 10.1016/j.celrep.2019.10.106
  
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sciencedirect.com/science/article/pii/S2211124719314391
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Genome-wide Analyses of Chromatin State in Human Mast Cells Reveal Molecular Drivers and Mediators of Allergic and Inflammatory Diseases

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_012918
  
  DOI: 10.1016/j.immuni.2019.09.021
  
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sciencedirect.com/science/article/pii/S1074761319304170
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A Unique Epigenomic Landscape Defines Human Erythropoiesis

1
1. scibot 13 Jan 2020
  
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  SCR_012918
  
  DOI: 10.1016/j.celrep.2019.08.020
  
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sciencedirect.com/science/article/pii/S2211124719310538
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:SCR_012918
  
  DOI: 10.1016/j.cell.2018.12.012
  
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sciencedirect.com/science/article/pii/S009286741831626X
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1. scibot 13 Jan 2020
  
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  RRID:SCR_012918
  
  DOI: 10.1016/j.celrep.2019.02.036
  
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sciencedirect.com/science/article/pii/S2211124719302074
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Untitled document

1
1. scibot 13 Jan 2020
  
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  DOI: 10.7554/eLife.43257
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6443350/
Nov 2018
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The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory

1
1. scibot 05 Nov 2018
  
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  RRID:SCR_012918
  
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sciencedirect.com/science/article/pii/S1074761318303960
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MYC Interacts with the G9a Histone Methyltransferase to Drive Transcriptional Repression and Tumorigenesis

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S153561081830415X
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HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis

1
1. scibot 05 Nov 2018
  
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Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells

1
1. scibot 05 Nov 2018
  
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  RRID:SCR_012918
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6126923/
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The Role of m6A/m-RNA Methylation in Stress Response Regulation

1
1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6069762/
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Untitled document

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6042962/
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The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0092867417314940
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Untitled document

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5734877/
europepmc.org europepmc.org

Untitled document

1
1. scibot 05 Nov 2018
  
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europepmc.org/articles/PMC5608512/
Nov 2017
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Layer-specific chromatin accessibility landscapes reveal regulatory networks in adult mouse visual cortex

1
1. scibot 08 Nov 2017
  
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  Curator: @kaitlinsung
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5325622/

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