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64 Matching Annotations

Aug 2025
www.biorxiv.org www.biorxiv.org

USP15: the fourth Proteasome-associated DUB

1
1. scibot 20 Aug 2025
  
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  RRID:SCR_013955
  
  DOI: 10.1101/2025.08.13.670075
  
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biorxiv.org/content/10.1101/2025.08.13.670075v1
Jul 2025
elifesciences.org elifesciences.org

Differential roles of NaV1.2 and NaV1.6 in neocortical pyramidal cell excitability

1
1. scibot 17 Jul 2025
  
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  DOI: 10.7554/eLife.105696
  
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elifesciences.org/articles/105696
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Engineering yeast multicellular behaviors via synthetic adhesion and contact signaling

1
1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.06.025
  
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sciencedirect.com/science/article/pii/S0092867425006919
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Uncovering novel lncRNAs linked to melanoma growth and migration with CRISPR-inhibition screening

1
1. scibot 11 Jul 2025
  
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  DOI: 10.1158/2767-9764.CRC-24-0416
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12238846/
Jun 2025
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Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity

1
1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115921
  
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sciencedirect.com/science/article/pii/S2211124725006928
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Lentiviral CRISPRa/i in the adult prairie vole brain: modulating neuronal gene expression without DNA cleavage

1
1. scibot 15 Jun 2025
  
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  DOI: 10.3389/fgeed.2025.1602983
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12162470/
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1-s2.0-S2589004225011162-main-html.html

1
1. scibot 11 Jun 2025
  
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  RRID:SCR_013955
  
  DOI: 10.1016/j.isci.2025.112855
  
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52.53.155.43/aade76b5737bfade2462ebc8caccc014a630e1a8/1-s2.0-S2589004225011162-main-html.html
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Precision genome editing and in-cell measurements of oxidative DNA damage repair enable functional and mechanistic characterization of cancer-associated MUTYH variants

1
1. scibot 02 Apr 2025
  
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  DOI: 10.1093/nar/gkaf037
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11952967/
Mar 2025
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Opposing roles for Bmp signalling during the development of electrosensory lateral line organs

1
1. scibot 28 Mar 2025
  
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  DOI: 10.7554/eLife.99798
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11936418/
Feb 2025
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Biosensor characterization: formal methods from the perspective of proteome fractions

1
1. scibot 16 Feb 2025
  
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  DOI: 10.1093/synbio/ysaf002
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11826058/
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SMAD4 and KRAS Status Shape Cancer Cell-Stromal Crosstalk and Therapeutic Response in Pancreatic Cancer

1
1. scibot 11 Feb 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-2330
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7617379/
Dec 2024
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High-throughput optimisation of protein secretion in yeast via an engineered biosensor

1
1. scibot 17 Dec 2024
  
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  DOI: 10.1016/j.tibtech.2024.11.010
  
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sciencedirect.com/science/article/pii/S0167779924003238
Nov 2024
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TXNIP mediates LAT1/SLC7A5 endocytosis to reduce amino acid uptake in cells entering quiescence

1
1. scibot 07 Nov 2024
  
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  RRID:SCR_013955
  
  DOI: 10.1101/2024.10.29.620655
  
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biorxiv.org/lookup/doi/10.1101/2024.10.29.620655
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer

2
1. scibot 31 Jul 2024
  
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  DOI: 10.1158/2159-8290.CD-23-0539
  
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2. scibot 31 Jul 2024
  
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  RRID:SCR_013955
  
  DOI: 10.1158/2159-8290.CD-23-0539
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
onlinelibrary.wiley.com onlinelibrary.wiley.com

The SASP factor IL-6 sustains cell-autonomous senescent cells via a cGAS-STING-NFκB intracrine senescent noncanonical pathway

1
1. scibot 23 Jul 2024
  
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  RRID:SCR_013955
  
  DOI: 10.1111/acel.14258
  
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onlinelibrary.wiley.com/doi/10.1111/acel.14258
Jun 2024
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CGG repeats in the human FMR1 gene regulate mRNA localization and cellular stress in developing neurons

1
1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.celrep.2024.114330
  
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sciencedirect.com/science/article/pii/S2211124724006582
May 2024
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SMAD4 and KRAS status shape malignant-stromal crosstalk in pancreatic cancer

1
1. scibot 23 May 2024
  
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  RRID:SCR_013955
  
  DOI: 10.1101/2024.04.28.591518
  
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biorxiv.org/content/10.1101/2024.04.28.591518v1
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Autophagy preferentially degrades non-fibrillar polyQ aggregates

1
1. scibot 17 May 2024
  
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  RRID:SCR_013955
  
  DOI: 10.1016/j.molcel.2024.04.018
  
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sciencedirect.com/science/article/pii/S1097276524003836
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Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas

1
1. scibot 03 May 2024
  
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  RRID:SCR_013955
  
  DOI: 10.1016/j.ccell.2024.04.007
  
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sciencedirect.com/science/article/pii/S1535610824001314
Mar 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Regulation of astrocyte metabolism by mitochondrial translocator protein 18 kDa

1
1. scibot 15 Mar 2024
  
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  DOI: 10.1111/jnc.16089
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.16089
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Engraftment of adult hematopoietic stem and progenitor cells in a novel model of humanized mice

1
1. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109238
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10904995/
Feb 2024
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Dose-Response Profiling in Heterologous Gene Expression: Insights from Proteome Fraction Analysis

1
1. scibot 09 Feb 2024
  
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  DOI: 10.1101/2023.12.01.569588
  
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biorxiv.org/content/10.1101/2023.12.01.569588v1
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Parkinson’s Disease Risk Enhancers in Microglia

1
1. scibot 08 Feb 2024
  
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  RRID:SCR_013955
  
  DOI: 10.1016/j.isci.2024.108921
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10845915/
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Intron Editing Reveals SNORD-Dependent Maturation of the Small Nucleolar RNA Host Gene GAS5 in Human Cells

1
1. scibot 28 Dec 2023
  
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  RRID:SCR_013955
  
  DOI: 10.3390/ijms242417621
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10743478/
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Glucose stress causes mRNA retention in nuclear Nab2 condensates

1
1. scibot 19 Dec 2023
  
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  RRID:SCR_013955
  
  DOI: 10.1016/j.celrep.2023.113593
  
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sciencedirect.com/science/article/pii/S2211124723016054
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Optogenetic manipulation of BMP signaling to drive chondrogenic differentiation of hPSCs

1
1. scibot 02 Dec 2023
  
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  RRID:SCR_013955
  
  DOI: 10.1016/j.celrep.2023.113502
  
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sciencedirect.com/science/article/pii/S2211124723015140
Nov 2023
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CRISPR-Cas12a-integrated transgenes in genomic safe harbors retain high expression in human hematopoietic iPSC-derived lineages and primary cells

1
1. scibot 29 Nov 2023
  
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  RRID:SCR_013955
  
  DOI: 10.1016/j.isci.2023.108287
  
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sciencedirect.com/science/article/pii/S2589004223023647
www.biorxiv.org www.biorxiv.org

ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers

1
1. scibot 03 Nov 2023
  
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  RRID:SCR_013955
  
  DOI: 10.1101/2023.10.24.563645
  
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biorxiv.org/content/10.1101/2023.10.24.563645v1
Aug 2023
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The Achromobacter type 3 secretion system drives pyroptosis and immunopathology via independent activation of NLRC4 and NLRP3 inflammasomes

1
1. scibot 23 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.113012
  
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sciencedirect.com/science/article/pii/S2211124723010239
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Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus

1
1. scibot 10 Aug 2023
  
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  RRID:SCR_013955
  
  DOI: 10.1038/s41467-023-40419-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10404257/
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Base editing enables duplex point mutagenesis in Clostridium autoethanogenum at the price of numerous off-target mutations

1
1. scibot 27 Jul 2023
  
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  RRID:SCR_013955
  
  DOI: 10.3389/fbioe.2023.1211197
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10366002/
Jun 2023
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Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer

1
1. scibot 01 Jun 2023
  
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  RRID:SCR_013955
  
  DOI: 10.1016/j.celrep.2023.112533
  
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sciencedirect.com/science/article/pii/S2211124723005442
May 2023
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Directed differentiation of human iPSCs into mesenchymal lineages by optogenetic control of TGF-β signaling

1
1. scibot 13 May 2023
  
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  RRID:SCR_013955
  
  DOI: 10.1016/j.celrep.2023.112509
  
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sciencedirect.com/science/article/pii/S221112472300520X
Nov 2022
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De-erosion of X chromosome dosage compensation by the editing of XIST regulatory regions restores the differentiation potential in hPSCs

1
1. scibot 30 Nov 2022
  
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  RRID:SCR_013955
  
  DOI: 10.1016/j.crmeth.2022.100352
  
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sciencedirect.com/science/article/pii/S2667237522002491
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TEMPO enables sequential genetic labeling and manipulation of vertebrate cell lineages

2
1. scibot 24 Nov 2022
  
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  SCR_013955
  
  DOI: 10.1016/j.neuron.2022.10.035
  
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2. scibot 24 Nov 2022
  
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  SCR_013955
  
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CRISPR-Cas9-induced gene knockout in zebrafish

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  DOI: 10.1016/j.xpro.2022.101779
  
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Functionally distinct NPAS4-expressing somatostatin interneuron ensembles critical for motor skill learning

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  DOI: 10.1016/j.neuron.2022.08.018
  
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Steroidogenic factor 1 (NR5A1) induces multiple transcriptional changes during differentiation of human gonadal-like cells

1
1. scibot 31 Aug 2022
  
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  RRID:SCR_013955
  
  DOI: 10.1016/j.diff.2022.08.001
  
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Colorectal cancer is associated with the presence of cancer driver mutations in normal colon

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  DOI: 10.1158/0008-5472.CAN-21-3607
  
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aacrjournals.org/cancerres/article/82/8/1492/694359/Colorectal-Cancer-Is-Associated-with-the-Presence
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Untitled document

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1. scibot 11 Aug 2021
  
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  DOI: 10.1093/bioinformatics/btw476
  
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Untitled document

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  DOI: 10.1093/bioinformatics/btw476
  
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Jul 2021
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Untitled document

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1. scibot 31 Jul 2021
  
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  DOI: 10.1016/j.cell.2019.02.023
  
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Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival

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1. scibot 27 Jul 2021
  
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  DOI: 10.7554/eLife.45248
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6611694/
Jun 2021
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Deletion of lncRNA XACT does not change expression dosage of X-linked genes, but affects differentiation potential in hPSCs

1
1. scibot 09 Jun 2021
  
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  RRID:SCR_013955
  
  DOI: 10.1016/j.celrep.2021.109222
  
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May 2021
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Non-photopic and photopic visual cycles differentially regulate immediate, early, and late phases of cone photoreceptor-mediated vision

1
1. scibot 12 May 2021
  
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  DOI: 10.1074/jbc.RA119.011374
  
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Mar 2021
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An optimized CRISPR/Cas9 approach for precise genome editing in neurons

1
1. scibot 17 Mar 2021
  
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  DOI: 10.7554/eLife.65202
  
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Sep 2020
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Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication

1
1. scibot 25 Sep 2020
  
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Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression

1
1. scibot 23 Sep 2020
  
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  DOI: 10.7554/eLife.56075
  
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Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses

1
1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.ebiom.2020.102786
  
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Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy

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1. scibot 16 Sep 2020
  
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  DOI: 10.7554/eLife.50843
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6984822/
Jan 2020
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Are Small Nucleolar RNAs “CRISPRable”? A Report on Box C/D Small Nucleolar RNA Editing in Human Cells

1
1. scibot 13 Jan 2020
  
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  SCR_013955
  
  DOI: 10.3389/fphar.2019.01246
  
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Unlimited Genetic Switches for Cell-Type-Specific Manipulation

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  DOI: 10.1016/j.neuron.2019.07.005
  
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Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research

1
1. scibot 13 Jan 2020
  
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  DOI: 10.7554/eLife.45829
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6579517/
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Bioprospecting Plant Growth-Promoting Rhizobacteria That Mitigate Drought Stress in Grasses

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_013955
  
  DOI: 10.3389/fmicb.2019.02106
  
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Untitled document

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  DOI: 10.1016/j.cell.2019.02.023
  
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Untitled document

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  DOI: 10.1016/j.devcel.2019.04.007
  
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sciencedirect.com/science/article/pii/S1534580719302771
Nov 2018
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Immunomimetic Designer Cells Protect Mice from MRSA Infection

1
1. scibot 05 Nov 2018
  
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  Benchling
  
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The Epstein-Barr Virus Regulome in Lymphoblastoid Cells

1
1. scibot 05 Nov 2018
  
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Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin

1
1. scibot 05 Nov 2018
  
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The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0092867417314940
Nov 2017
www.cell.com www.cell.com

Interspecies Chimerism with Mammalian Pluripotent Stem Cells

1
1. scibot 08 Nov 2017
  
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  CRISPR Design
  
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bioinformatics.oxfordjournals.org bioinformatics.oxfordjournals.org

CRISPR-DO for genome-wide CRISPR design and optimization

1
1. scibot 08 Nov 2017
  
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  SCR_013955
  
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