428 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structural insights into human zinc transporter ZnT1 mediated Zn2+ efflux
    1
    1. scibot 14 Nov 2024
      RRID:SCR_014222

      DOI: 10.1038/s44319-024-00287-3

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    pmc.ncbi.nlm.nih.gov/articles/PMC11549101/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional implications of the exon 9 splice insert in GluK1 kainate receptors
    1
    1. scibot 10 Nov 2024
      RRID:SCR_014222

      DOI: 10.7554/eLife.89755

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    pmc.ncbi.nlm.nih.gov/articles/PMC11540303/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRPML1 gating modulation by allosteric mutations and lipids
    1
    1. scibot 07 Nov 2024
      RRID:SCR_014222

      DOI: 10.7554/eLife.100987

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    ncbi.nlm.nih.gov/pmc/articles/PMC11473102/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
    1
    1. scibot 07 Nov 2024
      RRID:SCR_014222

      DOI: 10.1158/1535-7163.MCT-23-0487

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    pmc.ncbi.nlm.nih.gov/articles/PMC11286238/
  6. Oct 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Filament formation activates protease and ring nuclease activities of CRISPR Lon-SAVED
    1
    1. scibot 04 Oct 2024
      RRID:SCR_014222

      DOI: 10.1016/j.molcel.2024.09.002

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    sciencedirect.com/science/article/pii/S1097276524007354
  8. Sep 2024
  9. www.biorxiv.org www.biorxiv.org
    Type-II kinase inhibitors that target Parkinson’s Disease-associated LRRK2
    1
    1. scibot 28 Sep 2024
      RRID:SCR_014222

      DOI: 10.1101/2024.09.17.613365

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    biorxiv.org/content/10.1101/2024.09.17.613365v1
  10. www.sciencedirect.com www.sciencedirect.com
    Discovery and characterization of a pan-betacoronavirus S2-binding antibody
    1
    1. scibot 27 Sep 2024
      RRID:SCR_01422

      DOI: 10.1016/j.str.2024.08.022

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    sciencedirect.com/science/article/pii/S0969212624003691
  11. www.sciencedirect.com www.sciencedirect.com
    Dynamic allostery drives autocrine and paracrine TGF-β signaling
    1
    1. scibot 17 Sep 2024
      RRID:SCR_014222

      DOI: 10.1016/j.cell.2024.08.036

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    sciencedirect.com/science/article/pii/S0092867424009656
  12. Aug 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of the human heparan-α-glucosaminide N-acetyltransferase (HGSNAT)
    1
    1. scibot 30 Aug 2024
      RRID:SCR_014222

      DOI: 10.7554/eLife.93510

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    ncbi.nlm.nih.gov/pmc/articles/PMC11357348/
  14. www.sciencedirect.com www.sciencedirect.com
    Structural insights into the chloroplast protein import in land plants
    1
    1. scibot 28 Aug 2024
      RRID:SCR_014222

      DOI: 10.1016/j.cell.2024.08.003

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    sciencedirect.com/science/article/pii/S0092867424008948
  15. www.sciencedirect.com www.sciencedirect.com
    Conservation and specialization of the Ycf2-FtsHi chloroplast protein import motor in green algae
    1
    1. scibot 28 Aug 2024
      RRID:SCR_014222

      DOI: 10.1016/j.cell.2024.08.002

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    sciencedirect.com/science/article/pii/S0092867424008936
  16. www.sciencedirect.com www.sciencedirect.com
    Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination
    1
    1. scibot 18 Aug 2024
      RRID:SCR_014222

      DOI: 10.1016/j.xcrm.2024.101668

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    sciencedirect.com/science/article/pii/S2666379124003823
  17. europepmc.orghttp europepmc.orghttp
    Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes
    1
    1. scibot 02 Aug 2024
      COOT

      DOI: 10.1016/j.cell.2017.09.008

      Resource: Coot (RRID:SCR_014222)

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    europepmc.orghttp//europepmc.org/articles/PMC5651216/
  18. www.proquest.com www.proquest.com
    Mechanism of Ca2+ transport by ferroportin - ProQuest
    1
    1. scibot 02 Aug 2024
      RRID:SCR_014222

      DOI: 10.7554/eLife.82947

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    proquest.com/docview/2771288630
  19. Jul 2024
  20. www.sciencedirect.com www.sciencedirect.com
    Structure of the Hir histone chaperone complex
    1
    1. scibot 24 Jul 2024
      RRID:SCR_014222

      DOI: 10.1016/j.molcel.2024.05.031

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    sciencedirect.com/science/article/pii/S1097276524004787
  21. www.sciencedirect.com www.sciencedirect.com
    An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II
    1
    1. scibot 19 Jul 2024
      RRID:SCR_014222

      DOI: 10.1016/j.molcel.2024.06.006

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    sciencedirect.com/science/article/pii/S1097276524004842
  22. www.sciencedirect.com www.sciencedirect.com
    Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38
    1
    1. scibot 16 Jul 2024
      RRID:SCR_01422

      DOI: 10.1016/j.celrep.2024.114502

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    sciencedirect.com/science/article/pii/S2211124724008313
  23. Jun 2024
  24. www.sciencedirect.com www.sciencedirect.com
    A designed ankyrin-repeat protein that targets Parkinson’s disease-associated LRRK2
    1
    1. scibot 21 Jun 2024
      RRID:SCR_014222

      DOI: 10.1016/j.jbc.2024.107469

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    sciencedirect.com/science/article/pii/S0021925824019707
  25. www.sciencedirect.com www.sciencedirect.com
    Mechanism of heterochromatin remodeling revealed by the DDM1 bound nucleosome structures
    1
    1. scibot 21 Jun 2024
      RRID:SCR_014222

      DOI: 10.1016/j.str.2024.05.013

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    sciencedirect.com/science/article/pii/S0969212624001904
  26. www.sciencedirect.com www.sciencedirect.com
    POT1 recruits and regulates CST-Polα/primase at human telomeres
    1
    1. scibot 05 Jun 2024
      RRID:SCR_014222

      DOI: 10.1016/j.cell.2024.05.002

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    sciencedirect.com/science/article/pii/S0092867424004938
  27. www.sciencedirect.com www.sciencedirect.com
    Cryo-electron tomography reveals the packaging pattern of RuBisCOs in Synechococcus β-carboxysome
    1
    1. scibot 04 Jun 2024
      RRID:SCR_014222

      DOI: 10.1016/j.str.2024.05.007

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    sciencedirect.com/science/article/pii/S0969212624001849
  28. May 2024
  29. www.sciencedirect.com www.sciencedirect.com
    A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation
    1
    1. scibot 31 May 2024
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2024.114259

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    sciencedirect.com/science/article/pii/S2211124724005874
  30. Apr 2024
  31. www.sciencedirect.com www.sciencedirect.com
    Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses
    1
    1. scibot 26 Apr 2024
      RRID:SCR_014222

      DOI: 10.1016/j.immuni.2024.03.022

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    sciencedirect.com/science/article/pii/S1074761324001432
  32. www.nature.com www.nature.com
    Visualizing chaperone-mediated multistep assembly of the human 20S proteasome
    1
    1. scibot 11 Apr 2024
      RRID:SCR_014222

      DOI: 10.1038/s41594-024-01268-9

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    nature.com/articles/s41594-024-01268-9
  33. www.sciencedirect.com www.sciencedirect.com
    Staphylococcus aureus skin colonization is mediated by SasG lectin variation
    1
    1. scibot 04 Apr 2024
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2024.114022

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    sciencedirect.com/science/article/pii/S2211124724003504
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of ligand specificity and channel activation in an insect gustatory receptor
    1
    1. scibot 04 Apr 2024
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2024.114035

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    ncbi.nlm.nih.gov/pmc/articles/PMC11100771/
  35. Mar 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural mechanisms for VMAT2 inhibition by tetrabenazine
    1
    1. scibot 27 Mar 2024
      RRID:SCR_014222

      DOI: 10.7554/eLife.91973

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959523/
  37. www.sciencedirect.com www.sciencedirect.com
    Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance
    1
    1. scibot 22 Mar 2024
      RRID:SCR_014222

      DOI: 10.1016/j.immuni.2024.03.001

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    sciencedirect.com/science/article/pii/S1074761324000979
  38. www.sciencedirect.com www.sciencedirect.com
    ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat
    2
    1. scibot 15 Mar 2024
      RRID:SCR_014222

      DOI: 10.1016/j.cell.2024.02.013

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    2. scibot 15 Mar 2024
      RRID:SCR_014222

      DOI: 10.1016/j.cell.2024.02.013

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    sciencedirect.com/science/article/pii/S009286742400179X
  39. www.sciencedirect.com www.sciencedirect.com
    Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells
    1
    1. scibot 13 Mar 2024
      RRID:SCR_014222

      DOI: 10.1016/j.immuni.2024.02.008

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    sciencedirect.com/science/article/pii/S1074761324000840
  40. www.sciencedirect.com www.sciencedirect.com
    Structure of the plant plastid-encoded RNA polymerase
    2
    1. scibot 01 Mar 2024
      RRID:SCR_014222

      DOI: 10.1016/j.cell.2024.01.036

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    2. scibot 01 Mar 2024
      RRID:SCR_014222

      DOI: 10.1016/j.cell.2024.01.036

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    sciencedirect.com/science/article/pii/S009286742400103X
  41. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM structures of the plant plastid-encoded RNA polymerase
    1
    1. scibot 01 Mar 2024
      RRID:SCR_014222

      DOI: 10.1016/j.cell.2024.01.026

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    sciencedirect.com/science/article/pii/S0092867424000631
  42. Feb 2024
  43. aacrjournals.org aacrjournals.org
    A novel irreversible TEAD inhibitor, SWTX-143, blocks Hippo pathway transcriptional output and causes tumor regression in preclinical mesothelioma models
    1
    1. scibot 24 Feb 2024
      RRID:SCR_014222

      DOI: 10.1158/1535-7163.MCT-22-0681

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    aacrjournals.org/mct/article/23/1/3/732154/A-Novel-Irreversible-TEAD-Inhibitor-SWTX-143
  44. elifesciences.org elifesciences.org
    Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition
    1
    1. scibot 08 Feb 2024
      RRID:SCR_014222

      DOI: 10.7554/eLife.39611

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    elifesciences.org/articles/39611
  45. Jan 2024
  46. www.sciencedirect.com www.sciencedirect.com
    Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46
    1
    1. scibot 11 Jan 2024
      RRID:SCR_014222

      DOI: 10.1016/j.str.2023.12.001

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    sciencedirect.com/science/article/pii/S0969212623004434
  47. Dec 2023
  48. www.sciencedirect.com www.sciencedirect.com
    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
    1
    1. scibot 20 Dec 2023
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2023.113516

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    sciencedirect.com/science/article/pii/S2211124723015280
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    Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy
    1
    1. scibot 20 Dec 2023
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2023.113490

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    sciencedirect.com/science/article/pii/S2211124723015024
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    Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense
    1
    1. scibot 16 Dec 2023
      RRID:SCR_014222

      DOI: 10.1016/j.molcel.2023.11.007

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    sciencedirect.com/science/article/pii/S1097276523009498
  51. www.sciencedirect.com www.sciencedirect.com
    Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants
    1
    1. scibot 02 Dec 2023
      RRID:SCR_014222

      DOI: 10.1016/j.immuni.2023.11.004

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    sciencedirect.com/science/article/pii/S1074761323004855
  52. Nov 2023
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STX-478, a Mutant-Selective, Allosteric PI3Kα Inhibitor Spares Metabolic Dysfunction and Improves Therapeutic Response in PI3Kα-Mutant Xenografts
    1
    1. scibot 18 Nov 2023
      RRID:SCR_01422

      DOI: 10.1158/2159-8290.CD-23-0396

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      Curator: @jmitrevska

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    ncbi.nlm.nih.gov/pmc/articles/PMC10618743/
  54. www.sciencedirect.com www.sciencedirect.com
    Architecture of the bacteriophage lambda tail
    1
    1. scibot 03 Nov 2023
      RRID:SCR_014222

      DOI: 10.1016/j.str.2023.10.006

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    sciencedirect.com/science/article/pii/S0969212623003635
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Energy coupling and stoichiometry of Zn2+/H+ antiport by the prokaryotic cation diffusion facilitator YiiP
    1
    1. scibot 02 Nov 2023
      RRID:SCR_014222

      DOI: 10.7554/eLife.87167

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    ncbi.nlm.nih.gov/pmc/articles/PMC10617992/
  56. Oct 2023
  57. www.sciencedirect.com www.sciencedirect.com
    KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation
    1
    1. scibot 28 Oct 2023
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2023.113321

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    sciencedirect.com/science/article/pii/S2211124723013335
  58. www.sciencedirect.com www.sciencedirect.com
    Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly
    1
    1. scibot 28 Oct 2023
      RRID:SCR_014222coot

      DOI: 10.1016/j.molcel.2023.09.037

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    sciencedirect.com/science/article/pii/S1097276523008031
  59. www.nature.com www.nature.com
    A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response
    2
    1. scibot 20 Oct 2023
      RRID:SCR_014222

      DOI: 10.1038/s41556-023-01248-z

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  60. 52.53.155.43 52.53.155.43
    mct-22-0681-html.html
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    1. scibot 07 Oct 2023
      RRID:SCR_014222

      DOI: 10.1158/1535-7163.mct-22-0681

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  61. Sep 2023
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations
    1
    1. scibot 08 Sep 2023
      RRID:SCR_014222

      DOI: 10.1158/2159-8290.CD-23-0475

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  63. Aug 2023
  64. 52.53.155.43 52.53.155.43
    Phage T3 overcomes the BREX defense through SAM cleavage and inhibition of SAM synthesis by SAM lyase
    2
    1. scibot 18 Aug 2023
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2023.112972

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    52.53.155.43/0e339670ea77f60c3c58bff69139ee9d7a48f749/PIIS221112472300983X-html.html
  65. 52.53.155.43 52.53.155.43
    Recognition determinants of improved HIV-1 neutralization by a heavy chain matured pediatric antibody
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    1. scibot 17 Aug 2023
      RRID:SCR_014222

      DOI: 10.1016/j.isci.2023.107579

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  66. 52.53.155.43 52.53.155.43
    Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels
    2
    1. scibot 12 Aug 2023
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2023.112926

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  67. Jul 2023
  68. www.sciencedirect.com www.sciencedirect.com
    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
    1
    1. scibot 27 Jul 2023
      RRID:SCR_014222

      DOI: 10.1016/j.cell.2023.06.020

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    sciencedirect.com/science/article/pii/S0092867423006967
  69. www.sciencedirect.com www.sciencedirect.com
    Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+ T cell immunity
    1
    1. scibot 21 Jul 2023
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2023.112827

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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor
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    1. scibot 14 Jul 2023
      RRID:SCR_014222

      DOI: 10.7554/eLife.86029

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  71. 52.53.155.43 52.53.155.43
    cd-23-0475-html.html
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    1. scibot 13 Jul 2023
      RRID:SCR_014222

      DOI: 10.1158/2159-8290.cd-23-0475

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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural and functional properties of the transporter SLC26A6 reveal mechanism of coupled anion exchange
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    1. scibot 12 Jul 2023
      RRID:SCR_014222

      DOI: 10.7554/eLife.87178

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  73. Jun 2023
  74. www.sciencedirect.com www.sciencedirect.com
    A structural blueprint for interleukin-21 signal modulation
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    1. scibot 21 Jun 2023
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2023.112657

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  75. www.sciencedirect.com www.sciencedirect.com
    Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment
    1
    1. scibot 21 Jun 2023
      RRID:SCR_014222

      DOI: 10.1016/j.molcel.2023.05.036

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    sciencedirect.com/science/article/pii/S1097276523004203
  76. www.sciencedirect.com www.sciencedirect.com
    Centromere/kinetochore is assembled through CENP-C oligomerization
    1
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      RRID:SCR_014222

      DOI: 10.1016/j.molcel.2023.05.023

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  77. www.sciencedirect.com www.sciencedirect.com
    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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      RRID:SCR_014222

      DOI: 10.1016/j.chembiol.2023.05.007

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    sciencedirect.com/science/article/pii/S2451945623001502
  78. May 2023
  79. 52.53.155.43 52.53.155.43
    Structural and functional properties of the transporter SLC26A6 reveal mechanism of coupled anion exchange
    1
    1. scibot 25 May 2023
      RRID:S CR_01 4222

      DOI: 10.1101/2023.03.06.531323

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    52.53.155.43/6d6e42f4ace892f9f8318210e37bdd24819e1a2c/2023.03.06.531323v2.full-html.html
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-resolution structures with bound Mn2+ and Cd2+ map the metal import pathway in an Nramp transporter
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      RRID:SCR_014222

      DOI: 10.7554/eLife.84006

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    ncbi.nlm.nih.gov/pmc/articles/PMC10185341/
  81. www.sciencedirect.com www.sciencedirect.com
    Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response
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      RRID:SCR_014222

      DOI: 10.1016/j.str.2023.04.010

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    sciencedirect.com/science/article/pii/S0969212623001338
  82. Apr 2023
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structure of the endothelin-1-ETB-Gi complex
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    1. scibot 29 Apr 2023
      RRID:SCR_014222

      DOI: 10.7554/eLife.85821

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    ncbi.nlm.nih.gov/pmc/articles/PMC10129325/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural and functional properties of a plant NRAMP-related aluminum transporter
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      RRID:SCR_014222

      DOI: 10.7554/eLife.85641

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    ncbi.nlm.nih.gov/pmc/articles/PMC10115441/
  85. www.sciencedirect.com www.sciencedirect.com
    Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes
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      RRID:SCR_014222

      DOI: 10.1016/j.immuni.2023.03.009

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    sciencedirect.com/science/article/pii/S1074761323001292
  86. Mar 2023
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies
    1
    1. scibot 29 Mar 2023
      RRID:SCR_014222

      DOI: 10.1158/2767-9764.CRC-22-0306

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    ncbi.nlm.nih.gov/pmc/articles/PMC10035497/
  88. www.sciencedirect.com www.sciencedirect.com
    Immunodominant surface epitopes power immune evasion in the African trypanosome
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      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2023.112262

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    sciencedirect.com/science/article/pii/S2211124723002735
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of NF-κB p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation
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      RRID:SCR_014222

      DOI: 10.7554/eLife.86258

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    ncbi.nlm.nih.gov/pmc/articles/PMC9991059/
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster
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      RRID:SCR_014222

      DOI: 10.7554/eLife.84424

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    ncbi.nlm.nih.gov/pmc/articles/PMC9977279/
  91. Feb 2023
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation
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      RRID:SCR_014222

      DOI: 10.1126/sciadv.adg2997

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    ncbi.nlm.nih.gov/pmc/articles/PMC9931213/
  93. www.sciencedirect.com www.sciencedirect.com
    Structural basis of a transcription pre-initiation complex on a divergent promoter
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      RRID:SCR_014222

      DOI: 10.1016/j.molcel.2023.01.011

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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanism of Ca2+ transport by ferroportin
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      RRID:SCR_014222

      DOI: 10.7554/eLife.82947

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    ncbi.nlm.nih.gov/pmc/articles/PMC9883014/
  95. Jan 2023
  96. www.sciencedirect.com www.sciencedirect.com
    Nucleosome dyad determines the H1 C-terminus collapse on distinct DNA arms
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      RRID:SCR_014222

      DOI: 10.1016/j.str.2022.12.005

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    sciencedirect.com/science/article/pii/S0969212622004919
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    The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions
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      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2022.111902

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    sciencedirect.com/science/article/pii/S2211124722018010
  98. Dec 2022
  99. www.sciencedirect.com www.sciencedirect.com
    Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding
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      DOI: 10.1016/j.str.2022.11.008

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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of human phagocyte NADPH oxidase in the resting state
    1
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      RRID:SCR_014222

      DOI: 10.7554/eLife.83743

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    ncbi.nlm.nih.gov/pmc/articles/PMC9711523/
  101. Nov 2022
  102. www.sciencedirect.com www.sciencedirect.com
    Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes
    1
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      RRID:SCR_014222

      DOI: 10.1016/j.cell.2022.10.030

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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes
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      RRID:SCR_014222

      DOI: 10.1016/j.immuni.2022.10.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC9606073/
  104. www.sciencedirect.com www.sciencedirect.com
    IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling
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      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2022.111489

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  105. rupress.org rupress.org
    Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation
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  106. Oct 2022
  107. www.sciencedirect.com www.sciencedirect.com
    BefA, a microbiota-secreted membrane disrupter, disseminates to the pancreas and increases β cell mass
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  108. Sep 2022
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor
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  110. Aug 2022
  111. www.sciencedirect.com www.sciencedirect.com
    TITLE: Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways
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  112. www.sciencedirect.com www.sciencedirect.com
    Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC
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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope
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  114. Jul 2022
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conserved structural elements specialize ATAD1 as a membrane protein extraction machine
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  116. Jun 2022
  117. www.sciencedirect.com www.sciencedirect.com
    Rational exploration of fold atlas for human solute carrier proteins
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    Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex
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  119. May 2022
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry
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  121. Apr 2022
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    Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax
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    RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex
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    Structure of the poxvirus decapping enzyme D9 reveals its mechanism of cap recognition and catalysis
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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis Of Memory B Cells Identifies Conserved Neutralizing Epitopes On The N-Terminal Domain Of Variant SARS-Cov-2 Spike Proteins
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  126. elifesciences.org elifesciences.org
    Assembly of recombinant tau into filaments identical to those of Alzheimer’s disease and chronic traumatic encephalopathy
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  127. www.cell.com www.cell.com
    Facile discovery of surrogate cytokine agonists
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  128. Mar 2022
  129. www.sciencedirect.com www.sciencedirect.com
    Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses
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    Phosphosite-dependent Presentation of Dual Phosphorylated Peptides by MHC Class I Molecules
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  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for an unprecedented enzymatic alkylation in cylindrocyclophane biosynthesis
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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of nanobodies neutralizing SARS-CoV-2 variants
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    Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB
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    Structure and ion-release mechanism of PIB-4-type ATPases
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    Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance
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    Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel
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    Structural basis for catalyzed assembly of the Sonic hedgehog–Patched1 signaling complex
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  138. Feb 2022
  139. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti
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      DOI: 10.1186/s12915-022-01233-2

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  140. elifesciences.org elifesciences.org
    Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands
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    The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria
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    Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats
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      DOI: 10.7554/eLife.72908

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  143. elifesciences.org elifesciences.org
    Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family
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  144. Jan 2022
  145. elifesciences.org elifesciences.org
    Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes
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    Structural basis of bacteriophage lambda capsid maturation
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    Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1
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  149. Dec 2021
  150. www.sciencedirect.com www.sciencedirect.com
    Rational engineering enables co-crystallization and structural determination of the HIV-1 matrix-tRNA complex
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  151. Nov 2021
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    Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1
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  153. Oct 2021
  154. www.sciencedirect.com www.sciencedirect.com
    Pan-ebolavirus protective therapy by two multifunctional human antibodies
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    Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells
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  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural insights into the cis and trans assembly of human trophoblast cell surface antigen 2
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  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural characterization of NrnC identifies unifying features of dinucleotidases
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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural insights into the activation of human calcium-sensing receptor
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    TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells
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  160. Sep 2021
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    Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy
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    Structural basis and regulation of the reductive stress response
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    A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease
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    Atypical TNF-TNFR superfamily binding interface in the GITR-GITRL complex for T cell activation
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    Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies
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    Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace
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    A complete Protocadherin-19 ectodomain model for evaluating epilepsy-causing mutations and potential protein interaction sites
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    Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
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  171. Aug 2021
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    TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase
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    Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation
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    HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization
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    Protocol for the use of focused ion-beam milling to prepare crystalline lamellae for microcrystal electron diffraction (MicroED)
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  177. pubs.acs.org pubs.acs.org
    Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies
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    Fcab-HER2 Interaction: a Ménage à Trois. Lessons from X-Ray and Solution Studies
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    Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core
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    Structure and analysis of nanobody binding to the human ASIC1a ion channel
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    Cryo-EM structures of the caspase-activated protein XKR9 involved in apoptotic lipid scrambling
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase
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  193. Jul 2021
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    Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex
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    Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway
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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms
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  197. elifesciences.org elifesciences.org
    Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands
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  198. www.nature.com www.nature.com
    Regulation of the endosomal SNX27-retromer by OTULIN
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  199. elifesciences.org elifesciences.org
    Mechanism of pharmacochaperoning in a mammalian KATP channel revealed by cryo-EM
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  200. www.pnas.org www.pnas.org
    Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity
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  201. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Molecular docking predictions of fragrance binding to human leukocyte antigen molecules
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    STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition
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  203. www.sciencedirect.com www.sciencedirect.com
    Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues
    1
    1. scibot 29 Jul 2021
      COOT

      DOI: 10.1016/j.chembiol.2019.05.010

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    sciencedirect.com/science/article/pii/S2451945619301795
  204. www.sciencedirect.com www.sciencedirect.com
    Structural Basis of CD160:HVEM Recognition
    1
    1. scibot 29 Jul 2021
      COOT

      DOI: 10.1016/j.str.2019.05.010

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    sciencedirect.com/science/article/pii/S0969212619301728
  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of translationally inactive mammalian ribosomes
    1
    1. scibot 28 Jul 2021
      RRID:SCR_014222

      DOI: 10.7554/eLife.40486

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    ncbi.nlm.nih.gov/pmc/articles/PMC6226290/
  206. www.sciencedirect.com www.sciencedirect.com
    Characterization of MCU-Binding Proteins MCUR1 and CCDC90B — Representatives of a Protein Family Conserved in Prokaryotes and Eukaryotic Organelles
    1
    1. scibot 28 Jul 2021
      Coot

      DOI: 10.1016/j.str.2018.11.004

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    sciencedirect.com/science/article/pii/S0969212618304234
  207. www.sciencedirect.com www.sciencedirect.com
    Homer Tetramer Promotes Actin Bundling Activity of Drebrin
    1
    1. scibot 28 Jul 2021
      Coot

      DOI: 10.1016/j.str.2018.10.011

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    sciencedirect.com/science/article/pii/S0969212618303721
  208. www.sciencedirect.com www.sciencedirect.com
    Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor
    1
    1. scibot 28 Jul 2021
      COOT

      DOI: 10.1016/j.cell.2018.10.043

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    sciencedirect.com/science/article/pii/S0092867418313990
  209. www.sciencedirect.com www.sciencedirect.com
    Cross-Reactive Donor-Specific CD8+ Tregs Efficiently Prevent Transplant Rejection
    1
    1. scibot 28 Jul 2021
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2019.11.106

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    sciencedirect.com/science/article/pii/S2211124719316298
  210. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases
    1
    1. scibot 28 Jul 2021
      SCR_014222

      DOI: 10.7554/eLife.26111

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    ncbi.nlm.nih.gov/pmc/articles/PMC5468089/
  211. www.sciencedirect.com www.sciencedirect.com
    Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex
    2
    1. scibot 27 Jul 2021
      SCR_014222

      DOI: 10.1016/j.cell.2016.08.050

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    2. scibot 27 Jul 2021
      SCR_014222

      DOI: 10.1016/j.cell.2016.08.050

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    sciencedirect.com/science/article/pii/S0092867416311473
  212. www.sciencedirect.com www.sciencedirect.com
    Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition
    1
    1. scibot 27 Jul 2021
      Coot

      DOI: 10.1016/j.str.2018.10.007

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    sciencedirect.com/science/article/pii/S096921261830368X
  213. www.sciencedirect.com www.sciencedirect.com
    Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins
    1
    1. scibot 27 Jul 2021
      Coot

      DOI: 10.1016/j.neuron.2018.10.046

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    sciencedirect.com/science/article/pii/S0896627318309541
  214. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis
    1
    1. scibot 27 Jul 2021
      Coot

      DOI: 10.1016/j.molcel.2018.10.012

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    sciencedirect.com/science/article/pii/S109727651830844X
  215. www.sciencedirect.com www.sciencedirect.com
    Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched
    1
    1. scibot 27 Jul 2021
      COOT

      DOI: 10.1016/j.cell.2018.10.026

      Resource: Coot (RRID:SCR_014222)

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    sciencedirect.com/science/article/pii/S0092867418313795
  216. www.sciencedirect.com www.sciencedirect.com
    A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates
    1
    1. scibot 27 Jul 2021
      Coot

      DOI: 10.1016/j.celrep.2018.10.031

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    sciencedirect.com/science/article/pii/S2211124718316073
  217. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      SCR_014222

      DOI: 10.1016/j.celrep.2018.11.058

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    ncbi.nlm.nih.gov/pmc/articles/PMC6342559/
  218. Jun 2021
  219. www.sciencedirect.com www.sciencedirect.com
    Identification of an atypical interaction site in the BTB domain of the MYC-interacting zinc-finger protein 1
    1
    1. scibot 30 Jun 2021
      RRID:SCR_014222

      DOI: 10.1016/j.str.2021.06.005

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    sciencedirect.com/science/article/pii/S0969212621002094
  220. www.sciencedirect.com www.sciencedirect.com
    B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV
    1
    1. scibot 14 Jun 2021
      RRID:SCR_014222

      DOI: 10.1016/j.cell.2021.04.032

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    sciencedirect.com/science/article/pii/S0092867421005353
  221. May 2021
  222. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CM1-driven assembly and activation of yeast γ-tubulin small complex underlies microtubule nucleation
    1
    1. scibot 12 May 2021
      RRID:SCR_014222

      DOI: 10.7554/eLife.65168

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    ncbi.nlm.nih.gov/pmc/articles/PMC8099430/
  223. www.sciencedirect.com www.sciencedirect.com
    Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis
    1
    1. scibot 07 May 2021
      RRID:SCR_014222

      DOI: 10.1016/j.molcel.2020.08.010

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    sciencedirect.com/science/article/pii/S1097276520305530
  224. www.sciencedirect.com www.sciencedirect.com
    Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies
    1
    1. scibot 05 May 2021
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2021.109084

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    sciencedirect.com/science/article/pii/S2211124721004174
  225. Apr 2021
  226. www.sciencedirect.com www.sciencedirect.com
    Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1
    1
    1. scibot 29 Apr 2021
      RRID:SCR_014222

      DOI: 10.1016/j.chom.2021.02.018

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    sciencedirect.com/science/article/pii/S1931312821000974
  227. www.sciencedirect.com www.sciencedirect.com
    K27-Linked Diubiquitin Inhibits UCHL3 via an Unusual Kinetic Trap
    1
    1. scibot 28 Apr 2021
      RRID:SCR_014222

      DOI: 10.1016/j.chembiol.2020.11.005

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    sciencedirect.com/science/article/pii/S2451945620304347
  228. www.sciencedirect.com www.sciencedirect.com
    Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex
    1
    1. scibot 28 Apr 2021
      RRID:SCR_014222

      DOI: 10.1016/j.str.2021.04.003

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    sciencedirect.com/science/article/pii/S0969212621001192
  229. www.sciencedirect.com www.sciencedirect.com
    Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells
    1
    1. scibot 24 Apr 2021
      RRID:SCR_014222

      DOI: 10.1016/j.cell.2021.01.018

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    sciencedirect.com/science/article/pii/S0092867421000611
  230. www.sciencedirect.com www.sciencedirect.com
    The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design
    1
    1. scibot 14 Apr 2021
      RRID:SCR_014222

      DOI: 10.1016/j.immuni.2021.03.008

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    sciencedirect.com/science/article/pii/S1074761321001205
  231. www.sciencedirect.com www.sciencedirect.com
    Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form
    1
    1. scibot 14 Apr 2021
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2021.108986

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    sciencedirect.com/science/article/pii/S2211124721003004
  232. elifesciences.org elifesciences.org
    Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor
    1
    1. scibot 06 Apr 2021
      RRID:SCR_014222

      DOI: 10.7554/eLife.66097

      Resource: Coot (RRID:SCR_014222)

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    elifesciences.org/articles/66097