165 Matching Annotations
  1. Last 7 days
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    A BTB extension and ion-binding domain contribute to the pentameric structure and TFAP2A binding of KCTD1
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  3. Jan 2026
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    Molecular mechanism of MDA5 nucleation and filament formation by LGP2
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    Mechanisms of HSV-1 helicase-primase inhibition and replication fork complex assembly
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    Development of a colorimetric biosensor based on G-quadruplex aptamer and gold nanoparticles for rapid and sensitive detection of HPV18
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  7. Dec 2025
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    The role of kinase domain dimerization in EGFR activation
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  9. Nov 2025
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    Actin arginylation alters myosin engagement and F-actin patterning despite structural conservation
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  11. Sep 2025
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    Molecular basis of DNA recognition by the HMG-box-C1 module of capicua
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    Structural and functional insights into the evolution of SARS-CoV-2 KP.3.1.1 spike protein
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    Structural insights into the biotechnologically relevant reversible NADPH-oxidizing NiFe-hydrogenase from P. furiosus
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  17. May 2025
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    Structural mechanisms of PIP2 activation and SEA0400 inhibition in human cardiac sodium-calcium exchanger NCX1
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  19. Mar 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    23ME-01473, an Fc Effector–Enhanced Anti-ULBP6/2/5 Antibody, Restores NK Cell–Mediated Antitumor Immunity through NKG2D and FcγRIIIa Activation
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    SI/II Pocket of Ras: An Opportunity for a Once “Undruggable” Target
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  22. Feb 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structure of the F-tractin–F-actin complex
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  24. Jan 2025
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    Structural and functional analysis of the Nipah virus polymerase complex
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    Structure of the Nipah virus polymerase complex
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    Structure of WzxE the lipid III flippase for Enterobacterial Common Antigen polysaccharide
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    balıkçı-et-al-2024-structure-of-the-nipah-virus-polymerase-complex-html.html
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    Structure of the Nipah virus polymerase complex
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  30. Dec 2024
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    Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies
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    Structural insights into subunit-dependent functional regulation in epithelial sodium channels
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  33. Nov 2024
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cryo‐EM reveals transition states of the Acinetobacter baumannii F1 ‐ATPase rotary subunits γ and ε, unveiling novel compound targets
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  35. May 2024
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    A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation
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  37. Apr 2024
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    Staphylococcus aureus skin colonization is mediated by SasG lectin variation
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  39. Mar 2024
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    Structural mechanisms for VMAT2 inhibition by tetrabenazine
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    ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat
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  42. Jan 2024
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    Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46
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  44. Dec 2023
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    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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    Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense
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  47. Nov 2023
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    The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus
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    Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa
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  50. Oct 2023
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    KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation
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  52. Aug 2023
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    Recognition determinants of improved HIV-1 neutralization by a heavy chain matured pediatric antibody
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  54. Jul 2023
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    Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+ T cell immunity
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    Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor
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  57. May 2023
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    Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response
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  59. Mar 2023
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    Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster
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  61. Nov 2022
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    Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes
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  63. Aug 2022
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    TITLE: Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways
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  65. Jun 2022
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    Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex
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  67. Apr 2022
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    RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex
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    Analysis Of Memory B Cells Identifies Conserved Neutralizing Epitopes On The N-Terminal Domain Of Variant SARS-Cov-2 Spike Proteins
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  70. Mar 2022
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    Crystals of TELSAM–target protein fusions that exhibit minimal crystal contacts and lack direct inter-TELSAM contacts
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    Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel
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  73. Jan 2022
  74. elifesciences.org elifesciences.org
    Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes
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  75. Nov 2021
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    Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1
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  77. Oct 2021
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    Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells
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  80. Sep 2021
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    Atypical TNF-TNFR superfamily binding interface in the GITR-GITRL complex for T cell activation
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    Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies
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  84. Aug 2021
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    McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation
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    Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation
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    Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies
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    A Rare Lysozyme Crystal Form Solved Using Highly Redundant Multiple Electron Diffraction Datasets from Micron-Sized Crystals
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    Fcab-HER2 Interaction: a Ménage à Trois. Lessons from X-Ray and Solution Studies
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    Structure of Vps4 with circular peptides and implications for translocation of two polypeptide chains by AAA+ ATPases
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    Structure and analysis of nanobody binding to the human ASIC1a ion channel
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    Structures of translationally inactive mammalian ribosomes
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    Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase
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    Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex
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  98. Jul 2021
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway
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    Metazoan evolution of glutamate receptors reveals unreported phylogenetic groups and divergent lineage-specific events
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    Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes
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    Structures of translationally inactive mammalian ribosomes
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    Structural and functional characterization of an otopetrin family proton channel
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    Homer Tetramer Promotes Actin Bundling Activity of Drebrin
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    A Mutation Directs the Structural Switch of DNA Binding Proteins under Starvation to a Ferritin-like Protein Cage
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  107. Jun 2021
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    B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV
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  109. May 2021
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    Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP
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    Comprehensive analysis of genomic alterations, clinical outcomes, putative functions and potential therapeutic value of MMP11 in human breast cancer
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  112. Apr 2021
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    Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex
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  114. elifesciences.org elifesciences.org
    Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor
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    elifesciences.org/articles/66097
  115. Mar 2021
  116. www.cell.com www.cell.com
    Structure and immune recognition of the porcine epidemic diarrhea virus spike protein
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    cell.com/structure/fulltext/S0969-2126(20)30470-6
  117. Feb 2021
  118. elifesciences.org elifesciences.org
    A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery
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    elifesciences.org/articles/52158
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    Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody
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    cell.com/cell/abstract/S0092-8674(20)30057-X
  120. elifesciences.org elifesciences.org
    Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy
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    elifesciences.org/articles/48907
  121. Jan 2021
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations
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    ncbi.nlm.nih.gov/pmc/articles/PMC7781601/
  123. Dec 2020
  124. www.sciencedirect.com www.sciencedirect.com
    The Halastavi árva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism
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    A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide
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    cell.com/cell-reports/fulltext/S2211-1247(20)31417-0
  126. Nov 2020
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates
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    ncbi.nlm.nih.gov/pmc/articles/PMC7652416/
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of αE-catenin–F-actin catch bond behavior
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    ncbi.nlm.nih.gov/pmc/articles/PMC7588230/
  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cannabidiol interactions with voltage-gated sodium channels
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  130. Oct 2020
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