124 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HERC3 facilitates ERAD of select membrane proteins by recognizing membrane-spanning domains
    1
    1. scibot 14 Nov 2024
      RRID:SCR_014246

      DOI: 10.1083/jcb.202308003

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    pmc.ncbi.nlm.nih.gov/articles/PMC11082371/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular basis of neurodegeneration in a mouse model of Polr3-related disease
    1
    1. scibot 08 Nov 2024
      RRID:SCR_014246

      DOI: 10.7554/eLife.95314

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    pmc.ncbi.nlm.nih.gov/articles/PMC11537486/
  4. Sep 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pretargeted Radioimmunotherapy with the Novel Anti-oxMIF/HSG Bispecific Antibody ON105 Results in Significant Tumor Regression in Murine Models of Cancer
    1
    1. scibot 12 Sep 2024
      RRID:SCR_014246

      DOI: 10.1158/1535-7163.MCT-24-0083

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    ncbi.nlm.nih.gov/pmc/articles/PMC11372362/
  6. www.sciencedirect.com www.sciencedirect.com
    A chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer
    1
    1. scibot 04 Sep 2024
      RRID:SCR_014246

      DOI: 10.1016/j.chembiol.2024.08.003

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    sciencedirect.com/science/article/pii/S2451945624003234
  7. Aug 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A PDE3A-SLFN12 Molecular Glue Exhibits Significant Antitumor Activity in TKI-Resistant Gastrointestinal Stromal Tumors
    1
    1. scibot 22 Aug 2024
      RRID:SCR_014246

      DOI: 10.1158/1078-0432.CCR-24-0096

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    ncbi.nlm.nih.gov/pmc/articles/PMC11325149/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer
    1
    1. scibot 22 Aug 2024
      RRID:SCR_014246

      DOI: 10.1186/s13046-024-03124-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11321020/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small GTPase ActIvitY ANalyzing (SAIYAN) system: A method to detect GTPase activation in living cells
    1
    1. scibot 20 Aug 2024
      RRID:SCR_014246

      DOI: 10.1083/jcb.202403179

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    ncbi.nlm.nih.gov/pmc/articles/PMC11303508/
  11. Jul 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor invasiveness is regulated by the concerted function of APC, formins and Arp2/3 complex
    1
    1. scibot 10 Jul 2024
      RRID:SCR_014246

      DOI: 10.1016/j.isci.2024.109687

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    ncbi.nlm.nih.gov/pmc/articles/PMC11053316/
  13. Jun 2024
  14. 52.53.155.43 52.53.155.43
    1-s2.0-S258900422400909X-main-html.html
    1
    1. scibot 07 Jun 2024
      RRID:SCR_014246

      DOI: 10.5281/zenodo.8387899

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    52.53.155.43/976515401aa744b7f430b70e73bfee8344acae0c/1-s2.0-S258900422400909X-main-html.html
  15. www.sciencedirect.com www.sciencedirect.com
    POT1 recruits and regulates CST-Polα/primase at human telomeres
    1
    1. scibot 05 Jun 2024
      RRID:SCR_014246

      DOI: 10.1016/j.cell.2024.05.002

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    sciencedirect.com/science/article/pii/S0092867424004938
  16. May 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types
    1
    1. scibot 17 May 2024
      RRID:SCR_014246

      DOI: 10.1158/1078-0432.CCR-23-1763

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    ncbi.nlm.nih.gov/pmc/articles/PMC11094420/
  18. www.sciencedirect.com www.sciencedirect.com
    Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size
    1
    1. scibot 02 May 2024
      SCR_014246

      DOI: 10.1016/j.neuron.2024.04.006

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    sciencedirect.com/science/article/pii/S0896627324002447
  19. Feb 2024
  20. 52.53.155.43 52.53.155.43
    HERC3 E3 ligase provides an ERAD branch eliminating select membrane proteins
    1
    1. scibot 23 Feb 2024
      RRID:SCR_014246

      DOI: 10.1101/2023.10.16.562477

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    52.53.155.43/893a986f25098b75e101f0b7cb970068940c81b3/2023.10.16.562477v2.full-html.html
  21. elifesciences.org elifesciences.org
    Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition
    1
    1. scibot 08 Feb 2024
      RRID:SCR_014246

      DOI: 10.7554/eLife.39611

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    elifesciences.org/articles/39611
  22. Dec 2023
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer
    1
    1. scibot 15 Dec 2023
      RRID:SCR_014246

      DOI: 10.1371/journal.pgen.1011043

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    ncbi.nlm.nih.gov/pmc/articles/PMC10715669/
  24. Aug 2023
  25. link.springer.com link.springer.com
    Inhibition of acid sphingomyelinase reduces reactive astrocyte secretion of mitotoxic extracellular vesicles and improves Alzheimer’s disease pathology in the 5xFAD mouse
    1
    1. scibot 23 Aug 2023
      RRID:SCR_014246

      DOI: 10.1186/s40478-023-01633-7

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    link.springer.com/article/10.1186/s40478-023-01633-7
  26. Jul 2023
  27. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Obesity during preclinical Alzheimer's disease development exacerbates brain metabolic decline
    1
    1. scibot 05 Jul 2023
      RRID:SCR_014246

      DOI: 10.1111/jnc.15900

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15900
  28. Mar 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional hierarchy among different Rab27 effectors involved in secretory granule exocytosis
    1
    1. scibot 09 Mar 2023
      RRID:SCR_014246

      DOI: 10.7554/eLife.82821

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    ncbi.nlm.nih.gov/pmc/articles/PMC9988257/
  30. Jan 2023
  31. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Brain-derived neurotrophic factor (BDNF) induces antagonistic action to Nogo signaling by the upregulation of lateral olfactory tract usher substance (LOTUS) expression
    1
    1. scibot 14 Jan 2023
      RRID:SCR_014246

      DOI: 10.1111/jnc.15732

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15732
  32. Dec 2022
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Critical roles for ‘housekeeping’ nucleases in type III CRISPR-Cas immunity
    1
    1. scibot 31 Dec 2022
      RRID:SCR_014246

      DOI: 10.7554/eLife.81897

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    ncbi.nlm.nih.gov/pmc/articles/PMC9762709/
  34. link.springer.com link.springer.com
    LOTUS suppresses amyloid β-induced dendritic spine elimination through the blockade of amyloid β binding to PirB
    1
    1. scibot 13 Dec 2022
      RRID:SCR_014246

      DOI: 10.1186/s10020-022-00581-7

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    link.springer.com/article/10.1186/s10020-022-00581-7
  35. Nov 2022
  36. www.researchsquare.com www.researchsquare.com
    Home
    1
    1. scibot 11 Nov 2022
      RRID:SCR_014246

      DOI: 10.21203/rs.3.rs-658360/v1

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    researchsquare.com/
  37. rupress.org rupress.org
    Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation
    1
    1. scibot 01 Nov 2022
      RRID:SCR_014246

      DOI: 10.1083/jcb.202207022

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    rupress.org/jcb/article/221/12/e202207022/213573/Mitoguardin-2-mediated-lipid-transfer-preserves
  38. Oct 2022
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uncovering the mechanisms of transcription elongation by eukaryotic RNA polymerases I, II, and III
    1
    1. scibot 27 Oct 2022
      RRID:SCR_014246

      DOI: 10.1016/j.isci.2022.105306

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    ncbi.nlm.nih.gov/pmc/articles/PMC9593817/
  40. alzres.biomedcentral.com alzres.biomedcentral.com
    Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ
    1
    1. scibot 25 Oct 2022
      RRID:SCR_014246

      DOI: 10.1186/s13195-022-01096-3

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    alzres.biomedcentral.com/articles/10.1186/s13195-022-01096-3
  41. Jun 2022
  42. www.sciencedirect.com www.sciencedirect.com
    JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation
    1
    1. scibot 03 Jun 2022
      RRID:SCR_014246

      DOI: 10.1016/j.celrep.2022.110889

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    sciencedirect.com/science/article/pii/S2211124722006647
  43. www.sciencedirect.com www.sciencedirect.com
    A naturally DNase-free CRISPR-Cas12c enzyme silences gene expression
    1
    1. scibot 03 Jun 2022
      SCR_014246

      DOI: 10.1016/j.molcel.2022.04.020

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    sciencedirect.com/science/article/pii/S1097276522003835
  44. May 2022
  45. elifesciences.org elifesciences.org
    Enhanced C/EBPβ function promotes hypertrophic versus hyperplastic fat tissue growth and prevents steatosis in response to high-fat diet feeding
    1
    1. scibot 11 May 2022
      RRID:SCR_014246

      DOI: 10.7554/eLife.62625

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    elifesciences.org/articles/62625
  46. Apr 2022
  47. www.sciencedirect.com www.sciencedirect.com
    A unique mode of nucleic acid immunity performed by a multifunctional bacterial enzyme
    1
    1. scibot 14 Apr 2022
      RRID:SCR_014246

      DOI: 10.1016/j.chom.2022.03.001

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    sciencedirect.com/science/article/pii/S1931312822001305
  48. Mar 2022
  49. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Cardiomyocyte substructure reverts to an immature phenotype during heart failure
    1
    1. scibot 26 Mar 2022
      RRID:SCR_014246

      DOI: 10.1113/JP277273

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP277273
  50. www.eneuro.org www.eneuro.org
    The anti-diabetic drug metformin regulates voltage-gated sodium channel NaV1.7 via the ubiquitin-ligase NEDD4-2
    1
    1. scibot 08 Mar 2022
      RRID:SCR_014246

      DOI: 10.1523/ENEURO.0409-21.2022

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    eneuro.org/content/9/2/ENEURO.0409-21.2022
  51. Jan 2022
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors
    1
    1. scibot 07 Jan 2022
      RRID:SCR_014246

      DOI: 10.7554/eLife.68213

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    ncbi.nlm.nih.gov/pmc/articles/PMC8719881/
  53. Oct 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses
    1
    1. scibot 23 Oct 2021
      RRID:SCR_014246

      DOI: 10.1016/j.molcel.2021.10.003

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    sciencedirect.com/science/article/pii/S1097276521008327
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SUMOylation contributes to proteostasis of the chloroplast protein import receptor TOC159 during early development
    1
    1. scibot 11 Oct 2021
      RRID:SCR_014246

      DOI: 10.7554/eLife.60968

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    ncbi.nlm.nih.gov/pmc/articles/PMC8497054/
  56. Aug 2021
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    1. scibot 08 Aug 2021
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      DOI: 10.1002/jcp.26330

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    onlinelibrary.wiley.com/doi/10.1002/jcp.26330/full
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis
    1
    1. scibot 08 Aug 2021
      RRID:SCR_014246

      DOI: 10.7554/eLife.32572

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    ncbi.nlm.nih.gov/pmc/articles/PMC5809144/
  59. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Untitled document
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    1. scibot 06 Aug 2021
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      DOI: 10.1113/JP276714

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    physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP276714
  60. www.sciencedirect.com www.sciencedirect.com
    Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture, phosphorylation, and ubiquitylation
    1
    1. scibot 06 Aug 2021
      RRID:SCR_04246

      DOI: 10.1016/j.molcel.2021.07.013

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      Curator: @evieth

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      RRIDCUR:Incorrect RRIDCUR:Unresolved RRID:SCR_014246
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    sciencedirect.com/science/article/pii/S1097276521005827
  61. Jul 2021
  62. www.mdpi.com www.mdpi.com
    Recruitment of DNA Repair MRN Complex by Intrinsically Disordered Protein Domain Fused to Cas9 Improves Efficiency of CRISPR-Mediated Genome Editing
    1
    1. scibot 31 Jul 2021
      ImageQuant

      DOI: 10.3390/biom9100584

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    mdpi.com/2218-273X/9/10/584/htm
  63. www.embopress.org www.embopress.org
    Parkin‐mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes
    1
    1. scibot 30 Jul 2021
      ImageQuant

      DOI: 10.15252/embr.201947728

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    embopress.org/doi/full/10.15252/embr.201947728
  64. advances.sciencemag.org advances.sciencemag.org
    RNA binding activates RIG-I by releasing an autorepressed signaling domain
    1
    1. scibot 30 Jul 2021
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      DOI: 10.1126/sciadv.aax3641

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  65. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
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  67. elifesciences.org elifesciences.org
    Natural changes in light interact with circadian regulation at promoters to control gene expression in cyanobacteria
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    Input-Specific Metaplasticity in the Visual Cortex Requires Homer1a-Mediated mGluR5 Signaling
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    Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells
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    The alpha-1 subunit of the Na+,K+-ATPase (ATP1A1) is required for macropinocytic entry of respiratory syncytial virus (RSV) in human respiratory epithelial cells
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    Protein Kinase C Lambda Mediates Acid-Sensing Ion Channel 1a-Dependent Cortical Synaptic Plasticity and Pain Hypersensitivity
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    Translation attenuation by minocycline enhances longevity and proteostasis in old post-stress-responsive organisms
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    Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter
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    Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    The Exon Junction Complex Undergoes a Compositional Switch that Alters mRNP Structure and Nonsense-Mediated mRNA Decay Activity
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  81. europepmc.org europepmc.org
    A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants
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  82. May 2021
  83. www.sciencedirect.com www.sciencedirect.com
    Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway
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  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells
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  85. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  86. www.sciencedirect.com www.sciencedirect.com
    Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon
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    Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis
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  88. Feb 2021
  89. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nogo receptor antagonist LOTUS exerts suppression on axonal growth‐inhibiting receptor PIR‐B
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  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Homogentisic acid affects human osteoblastic functionality by oxidative stress and alteration of the Wnt/β‐catenin signaling pathway
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  91. Jan 2021
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ecd promotes U5 snRNP maturation and Prp8 stability
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Isoform-specific roles for AKT in affective behavior, spatial memory, and extinction related to psychiatric disorders
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  95. Dec 2020
  96. www.sciencedirect.com www.sciencedirect.com
    The Halastavi árva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism
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    CKIP-1 acts downstream to Cx43 on the activation of Nrf2 signaling pathway to protect from renal fibrosis in diabetes
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  98. Oct 2020
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    TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity
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    Eater cooperates with Multiplexin to drive the formation of hematopoietic compartments
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  101. Sep 2020
  102. journals.plos.org journals.plos.org
    Phosphorylation of mouse intestinal basolateral amino acid uniporter LAT4 is controlled by food-entrained diurnal rhythm and dietary proteins
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  103. elifesciences.org elifesciences.org
    Mechanisms of nucleotide selection by telomerase
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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression
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    Pre-emptive Quality Control of a Misfolded Membrane Protein by Ribosome-Driven Effects
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  107. elifesciences.org elifesciences.org
    CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks
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    Extraction of mRNA from Stalled Ribosomes by the Ski Complex
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  110. Jan 2020
  111. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Murine maternal dietary restriction affects neural Humanin expression and cellular profile
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    Input-Specific Metaplasticity in the Visual Cortex Requires Homer1a-Mediated mGluR5 Signaling
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    A Chaperone Lid Ensures Efficient and Privileged Client Transfer during Tail-Anchored Protein Targeting
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    The cAMP-EPAC Pathway Mediates PGE2-Induced FGF2 in Bovine Granulosa Cells
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    Pb inhibits hippocampal synaptic transmission via cyclin-dependent kinase-5 dependent Synapsin 1 phosphorylation
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    Stable STIM1 Knockdown in Self-Renewing Human Neural Precursors Promotes Premature Neural Differentiation
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    The Soluble Form of LOTUS inhibits Nogo Receptor-Mediated Signaling by Interfering with the Interaction Between Nogo Receptor Type 1 and p75 Neurotrophin Receptor
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    Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers
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    Structure and topology around the cleavage site regulate post-translational cleavage of the HIV-1 gp160 signal peptide
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    Insulin Inhibits Nrf2 Gene Expression via Heterogeneous Nuclear Ribonucleoprotein F/K in Diabetic Mice
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    The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention
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    N‐Glycosylation at Asn 402 Stabilizes N‐Cadherin and Promotes Cell–Cell Adhesion of Glioma Cells
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    Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) and Cyclin-dependent Kinase 5 (CDK5) Alters the Ratio of Its GAP Activity toward Ras and Rap GTPases
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    Exogenous α-Synuclein Decreases Raft Partitioning of Cav2.2 Channels Inducing Dopamine Release
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    Registered report: Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases
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    1. scibot 08 Nov 2017
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      Curator: @jcabotaj

      Resource used:

      (ImageQuant, RRID:SCR_014246)

      SciCrunch record: RRID:SCR_014246

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:SCR_014246 RRIDCUR:Missing
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    elifesciences.org/content/4/e07420