78 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    SHIP inhibition mediates select TREM2-induced microglial functions
    1
    1. scibot 16 Apr 2024
      RRID:SCR_014526

      DOI: 10.1016/j.molimm.2024.04.002

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    sciencedirect.com/science/article/pii/S0161589024000725
  3. link.springer.com link.springer.com
    Neurobehavioral dysfunction in a mouse model of Down syndrome: upregulation of cystathionine β-synthase, H2S overproduction, altered protein persulfidation, synaptic dysfunction, endoplasmic reticulum stress, and autophagy
    1
    1. scibot 11 Apr 2024
      RRID:SCR_014526

      DOI: 10.1007/s11357-024-01146-8

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    link.springer.com/article/10.1007/s11357-024-01146-8
  4. Mar 2024
  5. www.biorxiv.org www.biorxiv.org
    Metabolic and age-associated epigenetic barriers during direct reprogramming of mouse fibroblasts into induced cardiomyocytes
    1
    1. scibot 09 Mar 2024
      RRID:SCR_014526

      DOI: 10.1101/2024.02.28.582570

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    biorxiv.org/content/10.1101/2024.02.28.582570v1
  6. Feb 2024
  7. www.biorxiv.org www.biorxiv.org
    Parkinson's disease-related Miro1 mutation induces mitochondrial dysfunction and loss of dopaminergic neurons in vitro and in vivo
    2
    1. scibot 15 Feb 2024
      RRID:SCR_014526

      DOI: 10.1101/2023.12.19.571978

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    2. scibot 15 Feb 2024
      RRID:SCR_014526

      DOI: 10.1101/2023.12.19.571978

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    biorxiv.org/content/10.1101/2023.12.19.571978v1
  8. Jan 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle
    1
    1. scibot 25 Jan 2024
      RRID:SCR_014526

      DOI: 10.1016/j.neuron.2023.12.020

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    sciencedirect.com/science/article/pii/S0896627323009789
  10. www.sciencedirect.com www.sciencedirect.com
    Trem2 expression in microglia is required to maintain normal neuronal bioenergetics during development
    1
    1. scibot 06 Jan 2024
      RRID:SCR_014526

      DOI: 10.1016/j.immuni.2023.12.002

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    sciencedirect.com/science/article/pii/S1074761323005332
  11. Nov 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Insulin receptor loss impairs mammary tumorigenesis in mice
    1
    1. scibot 02 Nov 2023
      RRID:SCR_014526

      DOI: 10.1016/j.celrep.2023.113251

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    sciencedirect.com/science/article/pii/S2211124723012639
  13. Oct 2023
  14. www.sciencedirect.com www.sciencedirect.com
    PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors
    1
    1. scibot 28 Oct 2023
      RRID:SCR_014526

      DOI: 10.1016/j.celrep.2023.113329

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    sciencedirect.com/science/article/pii/S2211124723013414
  15. www.sciencedirect.com www.sciencedirect.com
    ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes
    1
    1. scibot 06 Oct 2023
      RRID:SCR_014526

      DOI: 10.1016/j.celrep.2023.113183

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    sciencedirect.com/science/article/pii/S2211124723011956
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMEM135 links peroxisomes to the regulation of brown fat mitochondrial fission and energy homeostasis
    1
    1. scibot 05 Oct 2023
      RRID:SCR_014526

      DOI: 10.1038/s41467-023-41849-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10541902/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer
    1
    1. scibot 05 Oct 2023
      RRID:SCR_014526

      DOI: 10.7554/eLife.85898

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    ncbi.nlm.nih.gov/pmc/articles/PMC10541180/
  18. Sep 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biosensor-integrated transposon mutagenesis reveals rv0158 as a coordinator of redox homeostasis in Mycobacterium tuberculosis
    1
    1. scibot 16 Sep 2023
      RRID:SCR_014526

      DOI: 10.7554/eLife.80218

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    ncbi.nlm.nih.gov/pmc/articles/PMC10501769/
  20. Aug 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Lower female survival from an opportunistic infection reveals progesterone-driven sex bias in trained immunity
    1
    1. scibot 29 Aug 2023
      RRID:SCR_014526

      DOI: 10.1016/j.celrep.2023.113007

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    sciencedirect.com/science/article/pii/S2211124723010185
  22. www.sciencedirect.com www.sciencedirect.com
    Ets1 facilitates EMT/invasion through Drp1-mediated mitochondrial fragmentation in ovarian cancer
    1
    1. scibot 23 Aug 2023
      RRID:SCR_014526

      DOI: 10.1016/j.isci.2023.107537

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    sciencedirect.com/science/article/pii/S2589004223016140
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression
    1
    1. scibot 10 Aug 2023
      RRID:SCR_014526

      DOI: 10.1016/j.isci.2023.107408

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    ncbi.nlm.nih.gov/pmc/articles/PMC10405072/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The sex-specific role of sensory neuron LKB1 on metabolic stress-induced mechanical hypersensitivity and mitochondrial respiration | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
    1
    1. scibot 02 Aug 2023
      RRID:SCR_014526

      DOI: 10.1152/ajpregu.00279.2021

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    ncbi.nlm.nih.gov/pmc/articles/PMC9306793/
  25. Jul 2023
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses
    1
    1. scibot 08 Jul 2023
      RRID:SCR_014526

      DOI: 10.1158/2643-3230.BCD-22-0029

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    ncbi.nlm.nih.gov/pmc/articles/PMC9816815/
  27. www.sciencedirect.com www.sciencedirect.com
    Glucose-induced CRL4COP1-p53 axis amplifies glycometabolism to drive tumorigenesis
    1
    1. scibot 05 Jul 2023
      RRID: SCR_014526

      DOI: 10.1016/j.molcel.2023.06.010

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      Curator: @sofiakhan13

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    sciencedirect.com/science/article/pii/S109727652300432X
  28. Jun 2023
  29. www.sciencedirect.com www.sciencedirect.com
    MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma
    1
    1. scibot 21 Jun 2023
      RRID: SCR_014526

      DOI: 10.1016/j.ccell.2023.05.015

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    sciencedirect.com/science/article/pii/S1535610823001824
  30. elifesciences.org elifesciences.org
    The CD73 immune checkpoint promotes tumor cell metabolic fitness
    1
    1. scibot 14 Jun 2023
      RRID:SCR_014526

      DOI: 10.7554/eLife.84508

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    elifesciences.org/articles/84508
  31. Apr 2023
  32. www.nature.com www.nature.com
    Glucocerebrosidase is imported into mitochondria and preserves complex I integrity and energy metabolism
    1
    1. scibot 11 Apr 2023
      RRID:SCR_014526

      DOI: 10.1038/s41467-023-37454-4

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    nature.com/articles/s41467-023-37454-4
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oncogene-mediated nuclear accumulation of lactate promotes epigenetic alterations to induce cancer cell proliferation
    1
    1. scibot 05 Apr 2023
      RRID:SCR_014526

      DOI: 10.1002/jcb.30381

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    onlinelibrary.wiley.com/doi/10.1002/jcb.30381
  34. Mar 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions
    1
    1. scibot 02 Mar 2023
      RRID:SCR_014526

      DOI: 10.1016/j.celrep.2023.112153

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    sciencedirect.com/science/article/pii/S221112472300164X
  36. Feb 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Peroxiredoxin 2 is required for the redox mediated adaptation to exercise
    1
    1. scibot 10 Feb 2023
      RRID:SCR_014526

      DOI: 10.1016/j.redox.2023.102631

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    sciencedirect.com/science/article/pii/S2213231723000320
  38. www.sciencedirect.com www.sciencedirect.com
    Ambient oxygen levels regulate intestinal dysbiosis and GVHD severity after allogeneic stem cell transplantation
    1
    1. scibot 03 Feb 2023
      RRID:SCR_014526

      DOI: 10.1016/j.immuni.2023.01.007

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    sciencedirect.com/science/article/pii/S1074761323000171
  39. www.nature.com www.nature.com
    Androgen receptor-dependent regulation of metabolism in high grade bladder cancer cells
    1
    1. scibot 01 Feb 2023
      RRID:SCR_014526

      DOI: 10.1038/s41598-023-28692-z

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    nature.com/articles/s41598-023-28692-z
  40. Jan 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P2RX7 enhances tumor control by CD8+ T cells in adoptive cell therapy
    1
    1. scibot 06 Jan 2023
      RRID:SCR_014526

      DOI: 10.1158/2326-6066.CIR-21-0691

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    ncbi.nlm.nih.gov/pmc/articles/PMC9250641/
  42. Sep 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Convergent cerebrospinal fluid proteomes and metabolic ontologies in humans and animal models of Rett syndrome
    1
    1. scibot 01 Sep 2022
      RRID:SCR_014526

      DOI: 10.1016/j.isci.2022.104966

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    sciencedirect.com/science/article/pii/S258900422201238X
  44. Aug 2022
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutamine metabolism modulates chondrocyte inflammatory response
    1
    1. scibot 22 Aug 2022
      RRID:SCR_014526

      DOI: 10.7554/eLife.80725

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    ncbi.nlm.nih.gov/pmc/articles/PMC9371604/
  46. www.sciencedirect.com www.sciencedirect.com
    SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis
    1
    1. scibot 17 Aug 2022
      RRID:SCR_014526

      DOI: 10.1016/j.celrep.2022.111233

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    sciencedirect.com/science/article/pii/S2211124722010506
  47. Jun 2022
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nicotinamide‐N‐methyltransferase is a promising metabolic drug target for primary and metastatic clear cell renal cell carcinoma
    1
    1. scibot 15 Jun 2022
      RRID:SCR_014526

      DOI: 10.1002/ctm2.883

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    ncbi.nlm.nih.gov/pmc/articles/PMC9178377/
  49. www.sciencedirect.com www.sciencedirect.com
    P53 regulates mitochondrial biogenesis via transcriptionally induction of mitochondrial ribosomal protein L12
    1
    1. scibot 10 Jun 2022
      RRID:SCR_014526

      DOI: 10.1016/j.yexcr.2022.113249

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    sciencedirect.com/science/article/pii/S0014482722002427
  50. www.sciencedirect.com www.sciencedirect.com
    Evaluating the glycolytic potential of mouse costimulated effector CD8+ T cells ex vivo
    1
    1. scibot 08 Jun 2022
      RRID:SCR_014526

      DOI: 10.1016/j.xpro.2022.101441

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    sciencedirect.com/science/article/pii/S2666166722003215
  51. Apr 2022
  52. link.springer.com link.springer.com
    Energetic metabolic reprogramming in Jurkat DFF40-deficient cancer cells
    1
    1. scibot 26 Apr 2022
      RRID:SCR_014526

      DOI: 10.1007/s11010-022-04433-0

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    link.springer.com/article/10.1007/s11010-022-04433-0
  53. www.sciencedirect.com www.sciencedirect.com
    Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease
    1
    1. scibot 08 Apr 2022
      RRID:SCR_014526

      DOI: 10.1016/j.stem.2022.03.003

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    sciencedirect.com/science/article/pii/S1934590922001011
  54. Mar 2022
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Triglyceride breakdown from lipid droplets regulates the inflammatory response in macrophages
    1
    1. scibot 26 Mar 2022
      RRID:SCR_014526

      DOI: 10.1073/pnas.2114739119

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    ncbi.nlm.nih.gov/pmc/articles/PMC8944848/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Applying Sodium Carbonate Extraction Mass Spectrometry to Investigate Defects in the Mitochondrial Respiratory Chain
    1
    1. scibot 18 Mar 2022
      RRID:SCR_014526

      DOI: 10.3389/fcell.2022.786268

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    ncbi.nlm.nih.gov/pmc/articles/PMC8921082/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nicotinamide Breaks Effector CD8 T cell Responses by Targeting mTOR Signaling
    1
    1. scibot 04 Mar 2022
      RRID:SCR_014526

      DOI: 10.1016/j.isci.2022.103932

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    ncbi.nlm.nih.gov/pmc/articles/PMC8886054/
  58. Feb 2022
  59. www.sciencedirect.com www.sciencedirect.com
    Blockage of citrate export prevents TCA cycle fragmentation via Irg1 inactivation
    1
    1. scibot 16 Feb 2022
      RRID:SCR_014526

      DOI: 10.1016/j.celrep.2022.110391

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    sciencedirect.com/science/article/pii/S2211124722001127
  60. Jan 2022
  61. www.sciencedirect.com www.sciencedirect.com
    Lipid droplet dynamics regulate adult muscle stem cell fate
    1
    1. scibot 19 Jan 2022
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      DOI: 10.1016/j.celrep.2021.110267

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  62. Dec 2021
  63. elifesciences.org elifesciences.org
    Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis
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      DOI: 10.7554/eLife.68487

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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted therapy to β3 integrin reduces chemoresistance in breast cancer bone metastases
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  65. Nov 2021
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    Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling
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    Reduced mitochondrial respiration in T cells of patients with major depressive disorder
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  68. Sep 2021
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    A hydride transfer complex reprograms NAD metabolism and bypasses senescence
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  70. Aug 2021
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    PGC1α is required for the renoprotective effect of lncRNA Tug1 in vivo and links Tug1 with urea cycle metabolites
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  73. Jul 2021
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation
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  75. link.springer.com link.springer.com
    PLCε regulates prostate cancer mitochondrial oxidative metabolism and migration via upregulation of Twist1
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  76. Jun 2021
  77. www.sciencedirect.com www.sciencedirect.com
    Type I interferon decreases macrophage energy metabolism during mycobacterial infection
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  78. May 2021
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    Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity
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  80. Apr 2021
  81. link.springer.com link.springer.com
    Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation
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  82. www.sciencedirect.com www.sciencedirect.com
    Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome
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  83. Mar 2021
  84. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nicotinamide ameliorates energy deficiency and improves retinal function in Cav‐1‐/‐ mice
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  85. Feb 2021
  86. elifesciences.org elifesciences.org
    Stable transplantation of human mitochondrial DNA by high-throughput, pressurized isolated mitochondrial delivery
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      DOI: 10.7554/eLife.63102

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  87. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Adenosine A2A receptor (A2AR) stimulation enhances mitochondrial metabolism and mitigates reactive oxygen species‐mediated mitochondrial injury
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      DOI: 10.1096/fj.201902459R

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  88. Jan 2021
  89. www.sciencedirect.com www.sciencedirect.com
    Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma
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      DOI: 10.1016/j.celrep.2020.108678

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  90. Nov 2020
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    CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion
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      DOI: 10.1016/j.stem.2020.10.015

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  92. Sep 2020
  93. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy
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    c-Src Promotes Tumorigenesis and Tumor Progression by Activating PFKFB3
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    HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection
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      DOI: 10.7554/eLife.55692

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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic reprogramming of fibro/adipogenic progenitors facilitates muscle regeneration
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      DOI: 10.26508/lsa.202000660

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  98. Jan 2020
  99. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Soluble adenylyl cyclase‐mediated cAMP signaling and the putative role of PKA and EPAC in cerebral mitochondrial function
    1
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      DOI: 10.1002/jnr.24477

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    Naa10p Inhibits Beige Adipocyte-Mediated Thermogenesis through N-α-acetylation of Pgc1α
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      DOI: 10.1016/j.molcel.2019.07.026

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    Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer
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      DOI: 10.1016/j.celrep.2019.06.010

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    BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis
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      DOI: 10.1016/j.cell.2019.06.005

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    NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8+ T Cells
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      DOI: 10.1016/j.celrep.2019.10.032

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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  105. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma
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  106. Nov 2018
  107. www.sciencedirect.com www.sciencedirect.com
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  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteomic and functional data sets on synaptic mitochondria from rats with genetic ablation of Parkin
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  109. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    onlinelibrary.wiley.com/doi/full/10.1002/jnr.24271
  110. Nov 2017
  111. www.sciencedirect.com www.sciencedirect.com
    MYC Controls Human Pluripotent Stem Cell Fate Decisions through Regulation of Metabolic Flux
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    Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies
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  113. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Simulated microgravity enhances oligodendrocyte mitochondrial function and lipid metabolism
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