103 Matching Annotations
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    Experimental evolution to thermal stress indicates climate resilience in a cosmopolitan arthropod
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    pmc.ncbi.nlm.nih.gov/articles/PMC13318303/
  3. Jul 2026
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    Arc mediates intercellular tau transmission via extracellular vesicles
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    sciencedirect.com/science/article/pii/S0092867426006951
  5. Jun 2026
  6. elifesciences.org elifesciences.org
    Distinct functions of cardiac β-adrenergic receptors in the T-tubule vs. outer surface membrane
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    elifesciences.org/articles/84243
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    Product-stabilized filamentation by human glutamine synthetase allosterically tunes metabolic activity
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    elifesciences.org/reviewed-preprints/108336v1
  8. Apr 2026
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    The Erlin1/2 complex is a dynamic scaffold for membrane microdomain assembly on the endoplasmic reticulum
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    cell.com/molecular-cell/abstract/S1097-2765(26)00157-7
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    RPA hyperphosphorylation hinders the resolution of R-loops and G-quadruplex-associated R-loops during RAS-driven senescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC13076219/
  11. Mar 2026
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    Metabolite-gated vascular contractility switch: OXGR1 activation mechanism enables agonist therapy for rosacea erythema
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    Mitochondrial fission during mitophagy requires both inner and outer mitofissins
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  14. Feb 2026
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    Synergistic mechanical and therapeutic modulation of engineered tumor cell-derived microparticles for enhanced cancer treatment
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  16. Dec 2025
  17. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    TDP-43 dysfunction compromises UPF1-dependent mRNA metabolism in ALS
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  18. Nov 2025
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    A small Candida glabrata protein promotes hyphal growth in C. albicans during mixed-species invasive candidiasis
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    Actin arginylation alters myosin engagement and F-actin patterning despite structural conservation
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  21. Oct 2025
  22. www.science.org www.science.org
    Mechanochemical waves in focal adhesions during cell migration
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    science.org/doi/10.1126/sciadv.adw6425
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    Mechanochemical waves in focal adhesions during cell migration
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  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Direct modulation of TRPM8 ion channels by rapamycin and analog macrolide immunosuppressants
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    Proteome mining of Yersinia Enterocolitica for drug targets and computational inhibitor identification with ADMET, anti-inflammation potential and formulation characteristics
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  26. Aug 2025
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  28. Jul 2025
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    Membrane curvature regulates Ups1 dependent phosphatidic acid transfer across lipid bilayers
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    Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate
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  32. Jun 2025
  33. www.scienceopen.com www.scienceopen.com
    Deciphering the Anti-Autism Potential of <i>Withania somnifera</i> Phytochemicals Targeting <i>SLC6A4</i> Through Computational Approaches
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  34. May 2025
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    Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates
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  36. Apr 2025
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phased high-quality genome of the gymnosperm Himalayan Yew assists in paclitaxel pathway exploration
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    A Systemic Immunoinformatics Approach to Design Combinatorial Multiepitope Vaccine Candidates against Vector-borne Bacterial Infections Exploiting the Proteomes of the Causative Agent and Vector for Scrub typhus
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  39. Mar 2025
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    A conformational fingerprint for amyloidogenic light chains
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  41. Feb 2025
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In silico molecular docking and molecular dynamic simulation of agarwood compounds with molecular targets of Alzheimer’s disease
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  43. Jan 2025
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    Passage of the HIV capsid cracks the nuclear pore
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    Intracellular protein-lipid interactions drive presynaptic assembly prior to neurexin recruitment
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  47. Oct 2024
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    Inhibitors of the small membrane (M) protein viroporin prevent Zika virus infection
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  49. Aug 2024
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    Pierced Lasso Topology Controls Function in Leptin
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  51. Jul 2024
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    Unraveling Structural Disparities in Human and Mycobacterium Tuberculosis Type-I Fatty Acid Synthase
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    biorxiv.org/content/10.1101/2024.07.17.603935v1
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    Heparan sulfate-dependent phase separation of CCL5 and its chemotactic activity
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    The release of host-derived antibodies bound to the variant surface glycoprotein (VSG) of Trypanosoma brucei cannot be explained by pH-dependent conformational changes of the VSG dimer
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  55. Jun 2024
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    Enhancing hepatoprotective action: oxyberberine amorphous solid dispersion system targeting TLR4
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  57. May 2024
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    Designing Combinatorial Multiepitope Vaccine Candidates against Scrub Typus by a Proteome-wide Immunoinfomatics Approach
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    Integration of genomic sequencing drives therapeutic targeting of PDGFRA in T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma
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  60. Feb 2024
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    Three-step docking by WIPI2, ATG16L1, and ATG3 delivers LC3 to the phagophore
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  62. Jan 2024
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    Design, synthesis and anticancer evaluation of novel arylhydrazones of active methylene compounds
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  64. Dec 2023
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    Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
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    Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy
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    Co-rotating twin screw process for continuous manufacturing of solid crystal suspension: A promising strategy to enhance the solubility, permeation and oral bioavailability of Carvedilol
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    Evolution towards simplicity in bacterial small heat shock protein system
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  69. Aug 2023
  70. 52.53.155.43 52.53.155.43
    Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels
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  71. Jul 2023
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanisms of MCL-1 protein stability induced by MCL-1 antagonists in B-cell malignancies
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    Computer-aided drug design approaches applied to screen natural product’s structural analogs targeting arginase in Leishmania spp
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  74. May 2023
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    A nanotherapeutic strategy that engages cytotoxic and immunosuppressive activities for the treatment of cancer recurrence following organ transplantation
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  76. Apr 2023
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    Selective killing of the human gastric pathogen Helicobacter pylori by mitochondrial respiratory complex I inhibitors
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    Entrectinib a Plausible Inhibitor for Osteopontin (SPP1) in Cervical Cancer—Integrated Bioinformatic Approach
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    Oncogene-mediated nuclear accumulation of lactate promotes epigenetic alterations to induce cancer cell proliferation
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  80. Mar 2023
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    Structures of NF-κB p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation
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    F1000Research Article: In silico molecular docking and molecular dynamic simulation of agarwood compounds with molecular targets of Alzheimer’s disease .
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  83. Feb 2023
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    DYF-5/MAK–dependent phosphorylation promotes ciliary tubulin unloading
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  85. Jan 2023
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  87. Dec 2022
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    Membrane curvature sensing and stabilization by the autophagic LC3 lipidation machinery
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    Exploiting ligand binding domain dimerization for development of novel androgen receptor inhibitors
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  90. Sep 2022
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    Anticancer potential of turmeric (<i>Curcuma longa</i>) ethanol extract and prediction of its mechanism through the Akt1 pathway
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  92. Aug 2022
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    Protocol to study the oligomeric organization of single-span transmembrane peptides using molecular dynamics simulations
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    Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC
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  95. Jun 2022
  96. journals.plos.org journals.plos.org
    Inhibition of histone H3-H4 chaperone pathways rescues C. elegans sterility by H2B loss
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  97. Mar 2022
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    Ligand-independent oligomerization of TACI is controlled by the transmembrane domain and regulates proliferation of activated B cells
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    Mg2+-dependent conformational equilibria in CorA and an integrated view on transport regulation
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  100. Feb 2022
  101. elifesciences.org elifesciences.org
    Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats
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    elifesciences.org/articles/72908
  102. Jan 2022
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor
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    ncbi.nlm.nih.gov/pmc/articles/PMC8730730/
  104. Oct 2021
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    A novel receptor for platelet-activating factor and lysophosphatidylcholine in Trypanosoma cruzi
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    onlinelibrary.wiley.com/doi/10.1111/mmi.14778
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cheonggukjang-Specific Component 1,3-Diphenyl-2-Propanone as a Novel PPARα/γ Dual Agonist: An In Vitro and In Silico Study
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  107. Aug 2021
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Simulating PIP2-Induced Gating Transitions in Kir6.2 Channels
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  109. onlinelibrary.wiley.com onlinelibrary.wiley.com
    DynaBiS: A Hierarchical Sampling Algorithm to Identify Flexible Binding Sites for Large Ligands and Peptides
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    onlinelibrary.wiley.com/doi/10.1002/prot.26182
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    onlinelibrary.wiley.com/doi/full/10.1002/jcb.27636
  111. Jul 2021
  112. link.springer.com link.springer.com
    Expression of Enterocin-P in HEK Platform: Evaluation of Its Cytotoxic Effects on Cancer Cell Lines and Its Potency to Interact with Cell-Surface Glycosaminoglycan by Molecular Modeling
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    link.springer.com/article/10.1007/s10989-019-09956-7
  113. elifesciences.org elifesciences.org
    Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics
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    elifesciences.org/articles/47150
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels
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    ncbi.nlm.nih.gov/pmc/articles/PMC6894927/
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    Intrinsic Structural Features of the Human IRE1α Transmembrane Domain Sense Membrane Lipid Saturation
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    sciencedirect.com/science/article/pii/S2211124719303249
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A fusion peptide in preS1 and the human protein disulfide isomerase ERp57 are involved in hepatitis B virus membrane fusion process
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    ncbi.nlm.nih.gov/pmc/articles/PMC8282342/
  117. Jun 2021
  118. elifesciences.org elifesciences.org
    Pore mutation N617D in the skeletal muscle DHPR blocks Ca2+ influx due to atypical high-affinity Ca2+ binding
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    elifesciences.org/articles/63435
  119. May 2021
  120. cancerres.aacrjournals.org cancerres.aacrjournals.org
    A spatial and functional interaction of a heterotetramer Survivin-DNA-PKcs complex in DNA damage response
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    cancerres.aacrjournals.org/content/81/9/2304
  121. Apr 2021
  122. www.sciencedirect.com www.sciencedirect.com
    Investigating GIPR (ant)agonism: A structural analysis of GIP and its receptor
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    sciencedirect.com/science/article/pii/S0969212621001179
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of a novel mCH3 conjugated anti-PcrV scFv molecule
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    ncbi.nlm.nih.gov/pmc/articles/PMC8010009/
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinetic analysis of ASIC1a delineates conformational signaling from proton-sensing domains to the channel gate
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    ncbi.nlm.nih.gov/pmc/articles/PMC8009679/
  125. Mar 2021
  126. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A conserved arginine with non‐conserved function is a key determinant of agonist selectivity in α7 nicotinic acetylcholine receptors
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15389
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    Pre-existing bilayer stresses modulate triglyceride accumulation in the ER versus lipid droplets
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    ncbi.nlm.nih.gov/pmc/articles/PMC7895522/
  128. Feb 2021
  129. www.cell.com www.cell.com
    The hitchhiker's guide to the periplasm: unexpected molecular interactions of polymyxin B1 in E. coli
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    cell.com/structure/abstract/S0969-2126(21)00009-5
  130. Dec 2020
  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11
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