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    Evasion of NKG2D-mediated cytotoxic immunity by sarbecoviruses
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    1. scibot 23 Apr 2024
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      DOI: 10.1016/j.cell.2024.03.026

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    Transcriptome analysis of Burkitt lymphoma cells treated with anti-convulsant drugs that are inhibitors of Epstein–Barr virus lytic reactivation
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      DOI: 10.1371/journal.pone.0299198

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    Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization
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    sciencedirect.com/science/article/pii/S1535610824001193
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    Early-onset colon cancer shows a distinct intestinal microbiome and a host-microbe interaction
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    aacrjournals.org/cancerpreventionresearch/article/17/1/29/732148/Early-onset-Colon-Cancer-Shows-a-Distinct
  6. Apr 2024
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    Dual-role transcription factors stabilize intermediate expression levels
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    PALB2-mutated human mammary cells display a broad spectrum of morphological and functional abnormalities induced by increased TGFβ signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11006627/
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    Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress
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    sciencedirect.com/science/article/pii/S2211124724003978
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    EP300/CREBBP acetyltransferase inhibition limits steroid receptor and FOXA1 signaling in prostate cancer cells
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    Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10993856/
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    Optimization of a mouse model of pancreatic cancer to simulate the human phenotypes of metastasis and cachexia
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    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
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    sciencedirect.com/science/article/pii/S2211124724003930
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    A senescence restriction point acting on chromatin integrates oncogenic signals
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    Telomere dysfunction alters intestinal stem cell dynamics to promote cancer
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    SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma
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    Developmental pyrethroid exposure disrupts molecular pathways for MAP kinase and circadian rhythms in mouse brain
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    1. scibot 03 Apr 2024
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      DOI: 10.1101/2023.08.28.555113

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  18. Mar 2024
  19. www.nature.com www.nature.com
    Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer
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    1. scibot 28 Mar 2024
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      DOI: 10.1038/s41598-024-57854-w

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    Mesenchyme instructs growth while epithelium directs branching in the mouse mammary gland
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      DOI: 10.7554/eLife.93326

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959526/
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    Xrp1 governs the stress response program to spliceosome dysfunction
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    A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture
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    1. scibot 23 Mar 2024
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      DOI: 10.7554/eLife.87726

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    Inflammatory, metabolic and sex-dependent gene-regulatory dynamics of microglia and macrophages in neonatal hippocampus after hypoxia-ischemia
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    Peripheral neuronal activation shapes the microbiome and alters gut physiology
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    1. scibot 22 Mar 2024
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    Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer
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    N-cadherin dynamically regulates pediatric glioma cell migration in complex environments
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      DOI: 10.1083/jcb.202401057

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    Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment
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    Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans
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    PUS1 regulates erythropoiesis via tRNA pseudouridylation and cytoplasmic translation
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    1. scibot 09 Mar 2024
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      DOI: 10.1016/j.isci.2024.109265

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    Genome-scale requirements for dynein-based transport revealed by a high-content arrayed CRISPR screen
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      DOI: 10.1083/jcb.202306048

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    Leishmania braziliensis enhances monocyte responses to promote anti-tumor activity
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      DOI: 10.1016/j.celrep.2024.113932

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    Modeling Molecular Pathogenesis of Idiopathic Pulmonary Fibrosis-Associated Lung Cancer in Mice
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      DOI: 10.1158/1541-7786.MCR-23-0480

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    Mosaic deletion of claudin-5 reveals rapid non-cell-autonomous consequences of blood-brain barrier leakage
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    sciencedirect.com/science/article/pii/S2211124724002390
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    Sexually dimorphic control of affective state processing and empathic behaviors
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      DOI: 10.1016/j.neuron.2024.02.001

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    sciencedirect.com/science/article/pii/S0896627324000850
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    Treatment response in first-line metastatic pancreatic ductal adenocarcinoma is stratified by a composite index of tumor proliferation and CD8 T cell infiltration
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      DOI: 10.1158/1078-0432.CCR-23-0535

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    CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression
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      DOI: 10.1158/1078-0432.CCR-23-0749

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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    De novo and histologically transformed small cell lung cancer is sensitive to lurbinectedin treatment through the modulation of EMT and NOTCH signaling pathways
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      DOI: 10.1158/1078-0432.CCR-23-0471

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  38. Feb 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
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      DOI: 10.1101/2024.02.02.578648

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    ncbi.nlm.nih.gov/pmc/articles/PMC10862846/
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    p53R245W mutation fuels cancer initiation and metastases in NASH-driven liver tumorigenesis
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      DOI: 10.1158/2767-9764.CRC-23-0218

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    aacrjournals.org/cancerrescommun/article/3/12/2640/732161/p53R245W-Mutation-Fuels-Cancer-Initiation-and
  41. aacrjournals.org aacrjournals.org
    PHF6-altered T-ALL harbor epigenetic repressive switch at bivalent promoters and respond to 5-azacitidine and venetoclax
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      DOI: 10.1158/1078-0432.CCR-23-2159

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    aacrjournals.org/clincancerres/article/30/1/94/732070/PHF6-altered-T-ALL-Harbor-Epigenetic-Repressive
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    An iron rheostat controls hematopoietic stem cell fate
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      DOI: 10.1016/j.stem.2024.01.011

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    sciencedirect.com/science/article/pii/S1934590924000419
  43. 52.53.155.43 52.53.155.43
    Transcriptional response of the heart to vagus nerve stimulation
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      DOI: 10.1152/physiolgenomics.00095.2023

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      DOI: 10.1152/physiolgenomics.00095.2023

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    52.53.155.43/1d74c7a9de06d0c8fd1f9db4b510dc74e1613524/kellett-et-al-2024-transcriptional-response-of-the-heart-to-vagus-nerve-stimulation-html.html
  44. 52.53.155.43 52.53.155.43
    Bacterial pneumonia-induced shedding of epithelial heparan sulfate inhibits the bactericidal activity of cathelicidin in a murine model
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    Differential Sensitivity to Longitudinal and Transverse Stretch Mediates Transcriptional Responses in Mouse Neonatal Ventricular Myocytes
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    The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer
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    Glycolytic enzyme PFKFB3 regulates sphingosinae 1-phosphate receptor 1 in proangiogenic glomerular endothelial cells under diabetic condition
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    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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    Recurrent Phases of Strict Protein Limitation Inhibit Tumor Growth and Restore Lifespan in A Drosophila Intestinal Cancer Model
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    Development of sexual dimorphism of skeletal muscles through the adrenal cortex, caused by androgen-induced global gene suppression
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    BRCA1 and ELK-1 regulate neural progenitor cell fate in the optic tectum in response to visual experience in Xenopus laevis tadpoles
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    Genomic exploration of the targets of FOXL2 and ESR2 unveils their implication in cell migration, invasion, and adhesion
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    O6-Methylguanine DNA Methyltransferase Regulates β-glucan-induced Trained Immunity of Macrophages via Farnesoid X Receptor and AMPK
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    Differential Regulation of the Stimulator of Interferon Genes pathway in Human Papillomavirus positive and negative Head and Neck Cancers
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    IL32 downregulation lowers triglycerides and type I collagen in di-lineage human primary liver organoids
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    Unique transcriptional profiles underlie osteosarcomagenesis driven by different p53 mutants
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    The Staphylococcus aureus CamS lipoprotein is a repressor of toxin production that shapes host-pathogen interaction
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    p53R245W mutation fuels cancer initiation and metastases in NASH-driven liver tumorigenesis
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    Targeting DNA Repair and Survival Signaling in Diffuse Intrinsic Pontine Gliomas to Prevent Tumor Recurrence
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    High Expression of THY1 in Intestinal Gastric Cancer as a Key Factor in Tumor Biology: A Poor Prognosis-Independent Marker Related to the Epithelial–Mesenchymal Transition Profile
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    Molecular organization of neuronal cell types and neuromodulatory systems in the zebrafish telencephalon
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    Upregulated LAMA3 modulates proliferation, adhesion, migration and epithelial‑to‑mesenchymal transition of cholangiocarcinoma cells
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    Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection.
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    Ethanol induces replication fork stalling and membrane stress in immortalized laryngeal cells
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    A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas
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    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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    Blimp-1 and c-Maf regulate  Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
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    The functional and molecular impact of triamcinolone acetonide on primary human bone marrow mesenchymal stem cells
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    Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis
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    Differential benefit of metronomic chemotherapy among triple negative breast cancer subtypes treated in the IBCSG Trial 22-00
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    Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia
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    Short-chain-fatty acid valerate reduces voluntary alcohol intake in male mice
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    Genomic and transcriptomic characterization of delta SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus)
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    Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions
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    Locus-specific proteome decoding reveals Fpt1 as a chromatin-associated negative regulator of RNA polymerase III assembly
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    Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51
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    Unraveling the molecular links between benzopyrene exposure, NASH, and HCC: an integrated bioinformatics and experimental study
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    Structured wound angiogenesis instructs mesenchymal barrier compartments in the regenerating nerve
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    Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence
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    Integrated Network Analysis of microRNAs, mRNAs, and Proteins Reveals the Regulatory Interaction between hsa-mir-200b and CFL2 Associated with Advanced Stage and Poor Prognosis in Patients with Intestinal Gastric Cancer
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    Population-specific Mutation Patterns in Breast Tumors from African American, European American, and Kenyan Patients
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    Blimp-1 and c-Maf regulate Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
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    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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    The hypoxia-regulated ectonucleotidase CD73 is a host determinant of HIV latency
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    Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model
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    Primary cilia control oligodendrocyte precursor cell proliferation in white matter injury via Hedgehog-independent CREB signaling
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    The effect of chronic lithium treatment on hippocampal progenitor cells: Transcriptomic analysis and systems pharmacology
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    CDK19 and CDK8 Mediator kinases drive androgen-independent in vivo growth of castration-resistant prostate cancer
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    Parity modulates impact of BMI and gestational weight gain on gut microbiota in human pregnancy
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    Distinct Hypoxia-induced Translational Profiles of Embryonic and Adult-derived Macrophages
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  129. www.nature.com www.nature.com
    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression
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    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2
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    Effectors Enabling Adaptation to Mitochondrial Complex I Loss in Hürthle Cell Carcinoma
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    A comparison of the impact on neuronal transcriptome and cognition of rAAV5 transduction with three different doses in the mouse hippocampus
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  163. Jul 2023
  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic analyses provide insights into the evolution and salinity adaptation of halophyte Tamarix chinensis
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    The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina
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    Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming
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    FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy
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  168. www.biorxiv.org www.biorxiv.org
    Increased susceptibility to ischemia causes exacerbated response to microinjuries in the cirrhotic liver
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  169. www.sciencedirect.com www.sciencedirect.com
    Nucleocytoplasmic mRNA redistribution accompanies RNA binding protein mislocalization in ALS motor neurons and is restored by VCP ATPase inhibition
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  170. www.biorxiv.org www.biorxiv.org
    Negative cell cycle regulation by Calcineurin is necessary for proper beta cell regeneration in zebrafish
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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors
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      DOI: 10.1158/0008-5472.CAN-21-4309

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  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prenatal Δ9-tetrahydrocannabinol exposure in males leads to motivational disturbances related to striatal epigenetic dysregulation
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  173. www.sciencedirect.com www.sciencedirect.com
    Global and tissue-specific aging effects on murine proteomes
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  174. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Obesity during preclinical Alzheimer's disease development exacerbates brain metabolic decline
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  175. www.sciencedirect.com www.sciencedirect.com
    Controlling genetic heterogeneity in gene-edited hematopoietic stem cells by single-cell expansion
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  176. Jun 2023
  177. 52.53.155.43 52.53.155.43
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  178. www.sciencedirect.com www.sciencedirect.com
    Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice
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  179. www.nature.com www.nature.com
    Extracellular vesicle-associated IGF2BP3 tunes Ewing sarcoma cell migration and affects PI3K/Akt pathway in neighboring cells
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  180. europepmc.org europepmc.org
    F1000Research Article: Integrative transcriptomic and proteomic study of Zika viral infection reveals potential mechanisms for oncolytic therapy in neuroblastoma.
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      DOI: 10.12688/f1000research.132627.1

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    An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
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    Transcriptomic landscape of early hair follicle and epidermal development
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    An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology
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    The maturation and aging trajectory of Marchantia polymorpha at single-cell resolution
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  185. www.embopress.org www.embopress.org
    DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres
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      DOI: 10.15252/embr.202256492

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  186. www.medrxiv.org www.medrxiv.org
    Metabolic signature and proteasome activity controls synovial migration of CDC42hiCD14+ cells in rheumatoid arthritis
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    Inhibition of high-fat diet-induced inflammatory responses in adipose tissue by SF1-expressing neurons of the ventromedial hypothalamus
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    IL-3 orchestrates ulcerative colitis pathogenesis by controlling the development and the recruitment of splenic reservoir neutrophils
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  189. dx.doi.org dx.doi.org
    MYC/glutamine dependency is a therapeutic vulnerability in pancreatic cancer with deoxycytidine kinase inactivation-induced gemcitabine resistance
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      DOI: 10.1158/1541-7786.MCR-22-0554

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  190. 52.53.155.43 52.53.155.43
    Interferon hyperactivity impairs cardiogenesis in Down syndrome via downregulation of canonical Wnt signaling
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  191. www.mdpi.com www.mdpi.com
    SAM-Competitive EZH2-Inhibitors Induce Platinum Resistance by EZH2-Independent Induction of ABC-Transporters
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      DOI: 10.3390/cancers15113043

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  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cellular heterogeneity in the 16HBE14o − airway epithelial line impacts biological readouts
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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating an Adaptive Immune Response with a Telomerase-mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma
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      DOI: 10.1158/1535-7163.MCT-23-0039

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  194. www.sciencedirect.com www.sciencedirect.com
    5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling
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  195. 52.53.155.43 52.53.155.43
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  196. May 2023
  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adipose tissue plasticity in pheochromocytoma patients suggests a role of the splicing machinery in human adipose browning
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  198. 52.53.155.43 52.53.155.43
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      DOI: 10.1210/endocr/bqad083

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  199. 52.53.155.43 52.53.155.43
    Efficient self-organization of blastoids solely from mouse ESCs is facilitated by transient reactivation of 2C gene network
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      DOI: 10.1101/2023.04.12.536583

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  200. 52.53.155.43 52.53.155.43
    Neural extracellular matrix regulates visual sensory motor integration
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  201. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Integrative transcriptomics and cell systems analyses reveal protective pathways controlled by Igfbp-3 in anthracycline-induced cardiotoxicity
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      DOI: 10.1096/fj.202201885RR

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  202. 52.53.155.43 52.53.155.43
    Intrinsic tumor resistance to CAR T cells is a dynamic transcriptional state that is exploitable with low-dose radiation
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      DOI: 10.1182/bloodadvances.2022009543

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  203. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptome network analysis implicates CX3CR1-positive type 3 dendritic cells in non-infectious uveitis
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      DOI: 10.7554/eLife.74913

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  204. www.sciencedirect.com www.sciencedirect.com
    Oxygen-induced pathological angiogenesis promotes intense lipid synthesis and remodeling in the retina
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      DOI: 10.1016/j.isci.2023.106777

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