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    PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma
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    Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma
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    SARS-CoV-2 infection exacerbates the cellular pathology of Parkinson’s disease in human dopaminergic neurons and a mouse model
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    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
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    Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation
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    A phosphate transporter in VIPergic neurons of the suprachiasmatic nucleus gates locomotor activity during the light/dark transition in mice
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  8. May 2024
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    Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems
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    RAD21 deficiency drives corneal to scleral differentiation fate switching via upregulating WNT9B
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    Positive and negative feedback regulation of the TGF-β1 explains two equilibrium states in skin aging
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    The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex
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    MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
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    Preclinical Multi-Omic Assessment of Pioglitazone in Skeletal Muscles of Mice Implanted with Human HER2/neu Overexpressing Breast Cancer Xenografts
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    The airway microbiome of persons with cystic fibrosis correlates with acquisition and microbiological outcomes of incident Stenotrophomonas maltophilia infection
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    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
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    Psilocybin Promotes Cell-Type-Specific Changes in the Orbitofrontal Cortex Revealed by Single-Nucleus RNA-seq
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    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
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    MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons
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  20. Apr 2024
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    ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection
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    Evasion of NKG2D-mediated cytotoxic immunity by sarbecoviruses
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    Transcriptome analysis of Burkitt lymphoma cells treated with anti-convulsant drugs that are inhibitors of Epstein–Barr virus lytic reactivation
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    Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization
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    Early-onset colon cancer shows a distinct intestinal microbiome and a host-microbe interaction
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    Dual-role transcription factors stabilize intermediate expression levels
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    PALB2-mutated human mammary cells display a broad spectrum of morphological and functional abnormalities induced by increased TGFβ signaling
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    Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress
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    EP300/CREBBP acetyltransferase inhibition limits steroid receptor and FOXA1 signaling in prostate cancer cells
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    Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells
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    Optimization of a mouse model of pancreatic cancer to simulate the human phenotypes of metastasis and cachexia
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    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
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    A senescence restriction point acting on chromatin integrates oncogenic signals
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    Telomere dysfunction alters intestinal stem cell dynamics to promote cancer
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    SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma
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    Developmental pyrethroid exposure disrupts molecular pathways for MAP kinase and circadian rhythms in mouse brain
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      DOI: 10.1101/2023.08.28.555113

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  37. Mar 2024
  38. www.nature.com www.nature.com
    Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer
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      DOI: 10.1038/s41598-024-57854-w

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    Mesenchyme instructs growth while epithelium directs branching in the mouse mammary gland
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      DOI: 10.7554/eLife.93326

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959526/
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    Xrp1 governs the stress response program to spliceosome dysfunction
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      DOI: 10.1093/nar/gkae055

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    A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture
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      DOI: 10.7554/eLife.87726

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    Inflammatory, metabolic and sex-dependent gene-regulatory dynamics of microglia and macrophages in neonatal hippocampus after hypoxia-ischemia
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      DOI: 10.1016/j.isci.2024.109346

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    Peripheral neuronal activation shapes the microbiome and alters gut physiology
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    Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer
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      DOI: 10.1158/1078-0432.CCR-23-0488

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    Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment
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    Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans
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    Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
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    PHF6-altered T-ALL harbor epigenetic repressive switch at bivalent promoters and respond to 5-azacitidine and venetoclax
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    Bacterial pneumonia-induced shedding of epithelial heparan sulfate inhibits the bactericidal activity of cathelicidin in a murine model
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    Differential Sensitivity to Longitudinal and Transverse Stretch Mediates Transcriptional Responses in Mouse Neonatal Ventricular Myocytes
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    Development of sexual dimorphism of skeletal muscles through the adrenal cortex, caused by androgen-induced global gene suppression
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    Genomic exploration of the targets of FOXL2 and ESR2 unveils their implication in cell migration, invasion, and adhesion
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    Cell-cycle-linked growth reprogramming encodes developmental time into leaf morphogenesis
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    Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis
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    Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia
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    Locus-specific proteome decoding reveals Fpt1 as a chromatin-associated negative regulator of RNA polymerase III assembly
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    Unraveling the molecular links between benzopyrene exposure, NASH, and HCC: an integrated bioinformatics and experimental study
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    Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence
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    Integrated Network Analysis of microRNAs, mRNAs, and Proteins Reveals the Regulatory Interaction between hsa-mir-200b and CFL2 Associated with Advanced Stage and Poor Prognosis in Patients with Intestinal Gastric Cancer
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    Population-specific Mutation Patterns in Breast Tumors from African American, European American, and Kenyan Patients
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    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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    Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model
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    Primary cilia control oligodendrocyte precursor cell proliferation in white matter injury via Hedgehog-independent CREB signaling
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    Parity modulates impact of BMI and gestational weight gain on gut microbiota in human pregnancy
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    Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.
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    Single-cell profiling of murine bladder cancer identifies sex-specific transcriptional signatures with prognostic relevance
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    Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice
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  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Imprinted Dlk1 dosage as a size determinant of the mammalian pituitary gland
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  168. Aug 2023
  169. www.biorxiv.org www.biorxiv.org
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2
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    Integrated single cell and bulk sequencing analysis identifies tumor reactive CXCR6+ CD8 T cells as a predictor of immune infiltration and immunotherapy outcomes in hepatocellular carcinoma
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    Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature
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    Interaction of an α-synuclein epitope with HLA-DRB1∗15:01 triggers enteric features in mice reminiscent of prodromal Parkinson’s disease
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    Circadian modulation by time-restricted feeding rescues brain pathology and improves memory in mouse models of Alzheimer’s disease
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    Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression
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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effectors Enabling Adaptation to Mitochondrial Complex I Loss in Hürthle Cell Carcinoma
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    Neuronal γ-secretase regulates lipid metabolism, linking cholesterol to synaptic dysfunction in Alzheimer’s disease
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    Integrative single-cell and bulk transcriptomes analyses identify intrinsic HNSCC subtypes with distinct prognoses and therapeutic vulnerabilities
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    Longitudinal map of transcriptome changes in the Lyme pathogen Borrelia burgdorferi during tick-borne transmission
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  180. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cooperative and competitive regulation of the astrocytic transcriptome by neurons and endothelial cells: Impact on astrocyte maturation
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  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A comparison of the impact on neuronal transcriptome and cognition of rAAV5 transduction with three different doses in the mouse hippocampus
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  182. Jul 2023
  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic analyses provide insights into the evolution and salinity adaptation of halophyte Tamarix chinensis
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    The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina
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    Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming
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    FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy
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  187. www.biorxiv.org www.biorxiv.org
    Increased susceptibility to ischemia causes exacerbated response to microinjuries in the cirrhotic liver
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    Nucleocytoplasmic mRNA redistribution accompanies RNA binding protein mislocalization in ALS motor neurons and is restored by VCP ATPase inhibition
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    Negative cell cycle regulation by Calcineurin is necessary for proper beta cell regeneration in zebrafish
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors
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  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prenatal Δ9-tetrahydrocannabinol exposure in males leads to motivational disturbances related to striatal epigenetic dysregulation
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    Global and tissue-specific aging effects on murine proteomes
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  193. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Obesity during preclinical Alzheimer's disease development exacerbates brain metabolic decline
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    Controlling genetic heterogeneity in gene-edited hematopoietic stem cells by single-cell expansion
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  195. Jun 2023
  196. 52.53.155.43 52.53.155.43
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  197. www.sciencedirect.com www.sciencedirect.com
    Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice
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  198. www.nature.com www.nature.com
    Extracellular vesicle-associated IGF2BP3 tunes Ewing sarcoma cell migration and affects PI3K/Akt pathway in neighboring cells
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      DOI: 10.1038/s41417-023-00637-8

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  199. europepmc.org europepmc.org
    F1000Research Article: Integrative transcriptomic and proteomic study of Zika viral infection reveals potential mechanisms for oncolytic therapy in neuroblastoma.
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      DOI: 10.12688/f1000research.132627.1

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    An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
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    Transcriptomic landscape of early hair follicle and epidermal development
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    An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology
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    The maturation and aging trajectory of Marchantia polymorpha at single-cell resolution
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