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Engineering a hemoglobin variant with enhanced stability and oxygen affinity using a protein language model

1
1. scibot 23 Oct 2026
  
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  RRID:SCR_015701
  
  DOI: 10.3389/fchem.2026.1898272
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13678298/
Apr 2026
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Mechanistic design of cell-penetrating disruptors for phospho-dependent TACC3-CHC interaction

1
1. scibot 30 Apr 2026
  
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  DOI: 10.1016/j.str.2026.04.001
  
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sciencedirect.com/science/article/pii/S0969212626001073
Mar 2026
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Intensity modulation of trichromatic split fluorescent proteins for live cell mapping

1
1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.crmeth.2026.101363
  
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sciencedirect.com/science/article/pii/S2667237526000639
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Paralog interference contributes to the preservation of genetic redundancy

1
1. scibot 03 Mar 2026
  
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  DOI: 10.1016/j.cub.2026.01.073
  
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sciencedirect.com/science/article/pii/S0960982226001454
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The pathway-independent positive allosteric modulator C1 allows for the identification of active Y4 receptor relevant positions

1
1. scibot 04 Feb 2026
  
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  DOI: 10.1007/s00018-025-06019-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12858701/
Jan 2026
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Cryo-EM structures of antibodies elicited by germline-targeting HIV MPER epitope scaffolds

1
1. scibot 13 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116818
  
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sciencedirect.com/science/article/pii/S2211124725015906
Aug 2025
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The HIV-1 nuclear export complex reveals the role of RNA in CRM1 cargo recognition

1
1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.molcel.2025.07.015
  
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sciencedirect.com/science/article/pii/S1097276525006161
Jan 2025
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Therapeutic Targeting and Structural Characterization of a Sotorasib-Modified KRAS G12C–MHC I Complex Demonstrate the Antitumor Efficacy of Hapten-Based Strategies

1
1. scibot 25 Jan 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-2450
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11733532/
Dec 2024
52.53.155.43 52.53.155.43

can-24-2450-html.html

1
1. scibot 19 Dec 2024
  
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  RRID:SCR_015701
  
  DOI: 10.1158/0008-5472.can-24-2450
  
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52.53.155.43/eda542f05a259fcd2586bec9365306e8eda4954b/can-24-2450-html.html
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The release of host-derived antibodies bound to the variant surface glycoprotein (VSG) of Trypanosoma brucei cannot be explained by pH-dependent conformational changes of the VSG dimer

1
1. scibot 03 Jul 2024
  
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  RRID:SCR_015701
  
  DOI: 10.12688/openreseurope.16783.1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11187536/
Apr 2024
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Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses

1
1. scibot 26 Apr 2024
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.immuni.2024.03.022
  
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sciencedirect.com/science/article/pii/S1074761324001432
Dec 2023
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Protein semisynthesis underscores the role of a conserved lysine in activation and desensitization of acid-sensing ion channels

1
1. scibot 19 Dec 2023
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.chembiol.2023.11.013
  
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sciencedirect.com/science/article/pii/S2451945623004300
Sep 2023
52.53.155.43 52.53.155.43

bpad021-html.html

1
1. scibot 29 Sep 2023
  
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  RRID:SCR_015701
  
  DOI: 10.1093/biomethods/bpad021
  
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52.53.155.43/027232968f206a1387bfd383c227b5333b4a771b/bpad021-html.html
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Narrow funnel-like interaction energy distribution is an indicator of specific protein interaction partner

2
1. scibot 15 Jun 2023
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.isci.2023.106911
  
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2. scibot 15 Jun 2023
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.isci.2023.106911
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10250834/
Mar 2023
www.mdpi.com www.mdpi.com

Effective Multivalent Oriented Presentation of Meningococcal NadA Antigen Trimers by Self-Assembling Ferritin Nanoparticles

1
1. scibot 30 Mar 2023
  
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  RRID:SCR_015701
  
  DOI: 10.3390/ijms24076183
  
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mdpi.com/1422-0067/24/7/6183
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines

1
1. scibot 22 Mar 2023
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.celrep.2023.112266
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9986124/
Dec 2022
www.nature.com www.nature.com

Structural basis for Parkinson’s disease-linked LRRK2’s binding to microtubules

1
1. scibot 13 Dec 2022
  
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  RRID:SCR_015701
  
  DOI: 10.1038/s41594-022-00863-y
  
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nature.com/articles/s41594-022-00863-y
Aug 2022
www.sciencedirect.com www.sciencedirect.com

TITLE: Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways

1
1. scibot 31 Aug 2022
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.isci.2022.104914
  
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sciencedirect.com/science/article/pii/S2589004222011865
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Protocol to identify host-viral protein interactions between coagulation-related proteins and their genetic variants with SARS-CoV-2 proteins

1
1. scibot 27 Aug 2022
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.xpro.2022.101648
  
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sciencedirect.com/science/article/pii/S2666166722005287
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Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC

1
1. scibot 22 Aug 2022
  
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  DOI: 10.1016/j.cell.2022.07.010
  
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sciencedirect.com/science/article/pii/S0092867422009138
May 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Computational Site Saturation Mutagenesis of Canonical and Non-Canonical Amino Acids to Probe Protein-Peptide Interactions

1
1. scibot 05 May 2022
  
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  RRID:SCR_015701
  
  DOI: 10.3389/fmolb.2022.848689
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9047896/
Dec 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Conformational dynamics of auto-inhibition in the ER calcium sensor STIM1

1
1. scibot 11 Dec 2021
  
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  RRID:SCR_015701
  
  DOI: 10.7554/eLife.66194
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8651296/
Oct 2021
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Pan-ebolavirus protective therapy by two multifunctional human antibodies

1
1. scibot 29 Oct 2021
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.cell.2021.09.035
  
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sciencedirect.com/science/article/pii/S009286742101165X
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

DnaB helicase is recruited to the replication initiation complex via binding of DnaA domain I to the lateral surface of the DnaB N-terminal domain

1
1. scibot 15 Aug 2021
  
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  RRID:SCR_015701
  
  DOI: 10.1074/jbc.RA120.014235
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7415982/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core

1
1. scibot 05 Aug 2021
  
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  RRID:SCR_015701
  
  DOI: 10.7554/eLife.37688
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6237438/
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Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies

1
1. scibot 02 Aug 2021
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.chom.2019.04.011
  
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sciencedirect.com/science/article/pii/S1931312819302148
Jul 2021
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Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies

1
1. scibot 29 Jul 2021
  
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  RRID: SCR_015701
  
  DOI: 10.1016/j.chom.2019.10.002
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1931312819305268
Jun 2021
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RelA-SpoT Homolog toxins pyrophosphorylate the CCA end of tRNA to inhibit protein synthesis

1
1. scibot 26 Jun 2021
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.molcel.2021.06.005
  
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sciencedirect.com/science/article/pii/S1097276521004524
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Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity

1
1. scibot 25 Jun 2021
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.ccell.2021.06.001
  
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sciencedirect.com/science/article/pii/S1535610821002841
Mar 2021
www.cell.com www.cell.com

Structure and immune recognition of the porcine epidemic diarrhea virus spike protein

1
1. scibot 21 Mar 2021
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.str.2020.12.003
  
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  Curator: @evieth
  
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  RRID:SCR_015701 RRIDCUR:Validated
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cell.com/structure/fulltext/S0969-2126(20)30470-6
Feb 2021
elifesciences.org elifesciences.org

A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery

1
1. scibot 25 Feb 2021
  
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  RRID:SCR_015701
  
  DOI: 10.7554/eLife.52158
  
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elifesciences.org/articles/52158
Dec 2020
elifesciences.org elifesciences.org

The structures of secretory and dimeric immunoglobulin A

1
1. scibot 09 Dec 2020
  
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  RRID:SCR_015701
  
  DOI: 10.7554/eLife.56098
  
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elifesciences.org/articles/56098
www.cell.com www.cell.com

A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide

1
1. scibot 07 Dec 2020
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.celrep.2020.108428
  
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  Curator: @Naa003
  
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cell.com/cell-reports/fulltext/S2211-1247(20)31417-0
Oct 2020
elifesciences.org elifesciences.org

Allosteric mechanism for KCNE1 modulation of KCNQ1 potassium channel activation

1
1. scibot 31 Oct 2020
  
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  RRID:SCR_015701
  
  DOI: 10.7554/eLife.57680
  
  Resource: Rosetta (RRID:SCR_015701)
  
  Curator: @evieth
  
  SciCrunch record: RRID:SCR_015701
  
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  RRID:SCR_015701 RRIDCUR:Validated
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elifesciences.org/articles/57680
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Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses

1
1. scibot 29 Oct 2020
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.immuni.2020.10.005
  
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  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S1074761320304465
Sep 2020
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Approaching boiling point stability of an alcohol dehydrogenase through computationally-guided enzyme engineering

1
1. scibot 17 Sep 2020
  
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  RRID:SCR_015701
  
  DOI: 10.7554/eLife.54639
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7164962/
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Cryo-EM Reveals Integrin-Mediated TGF-β Activation without Release from Latent TGF-β

3
1. scibot 16 Sep 2020
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.cell.2019.12.030
  
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2. scibot 03 Sep 2020
  
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  DOI: 10.1016/j.cell.2019.12.030
  
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  RRID: SCR_015701
  
  DOI: 10.1016/j.cell.2019.12.030
  
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Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens

1
1. scibot 10 Sep 2020
  
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  RRID:SCR_015701
  
  DOI: 10.7554/eLife.57659
  
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Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization

1
1. scibot 10 Sep 2020
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.immuni.2020.01.001
  
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sciencedirect.com/science/article/pii/S1074761320300285
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Specificity and affinity of the N-terminal residues in staphylocoagulase in binding to prothrombin

1
1. scibot 09 Sep 2020
  
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  RRID:SCR_015701
  
  DOI: 10.1074/jbc.RA120.012588
  
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elifesciences.org elifesciences.org

Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5

1
1. scibot 04 Sep 2020
  
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  RRID:SCR_015701
  
  DOI: 10.7554/eLife.38770
  
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Jan 2020
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Structural Insight into Eukaryotic Sterol Transport through Niemann-Pick Type C Proteins

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.cell.2019.08.038
  
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Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.chembiol.2019.09.002
  
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Structure-based inhibitors of amyloid beta core suggest a common interface with tau

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_015701
  
  DOI: 10.7554/eLife.46924
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6850776/
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Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.immuni.2019.10.008
  
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Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_015701
  
  DOI: 10.1016/j.celrep.2019.08.052
  
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sciencedirect.com/science/article/pii/S2211124719311003
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.7554/eLife.45345
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6449081/
Nov 2018
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Structure of the human epithelial sodium channel by cryo-electron microscopy

1
1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6197857/
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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6185872/
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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1931312818304876
elifesciences.org elifesciences.org

Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments

1
1. scibot 05 Nov 2018
  
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elifesciences.org/articles/36392
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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6092121/
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ncbi.nlm.nih.gov/pmc/articles/PMC6086657/
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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6019066/
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Structure of the CLC-1 chloride channel from Homo sapiens

1
1. scibot 05 Nov 2018
  
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  RRID:SCR_015701
  
  Curator: @evieth
  
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elifesciences.org/articles/36629
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Development of a Prototype System for Archiving Integrative/Hybrid Structure Models of Biological Macromolecules

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0969212618300923
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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5655540/
europepmc.org europepmc.org

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1. scibot 05 Nov 2018
  
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