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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A BTB extension and ion-binding domain contribute to the pentameric structure and TFAP2A binding of KCTD1

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.str.2024.07.023
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7618933/
Aug 2025
52.53.155.43 52.53.155.43

41594_2025_1631_MOESM4_ESM-html.html

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1. scibot 13 Aug 2025
  
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  DOI: 10.5281/zenodo.14243720
  
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52.53.155.43/2894f1585e3ca7aaaea575ab75ca401271c73618/41594_2025_1631_MOESM4_ESM-html.html
Jul 2025
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Type II kinase inhibitors that target Parkinson’s disease–associated LRRK2

1
1. scibot 25 Jul 2025
  
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  DOI: 10.1126/sciadv.adt2050
  
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science.org/doi/10.1126/sciadv.adt2050
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

M4205 (IDRX-42) Is a Highly Selective and Potent Inhibitor of Relevant Oncogenic Driver and Resistance Variants of KIT in Cancer

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1. scibot 04 Jul 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12214875/
Jun 2025
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Type II kinase inhibitors that target Parkinson’s disease–associated LRRK2

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1. scibot 11 Jun 2025
  
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  DOI: 10.1126/sciadv.adt2050
  
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science.org/doi/10.1126/sciadv.adt2050
May 2025
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PNUTS:PP1 recruitment to Tox4 regulates chromosomal dispersal in Drosophila germline development

1
1. scibot 17 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115693
  
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sciencedirect.com/science/article/pii/S2211124725004644
Mar 2025
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23ME-01473, an Fc Effector–Enhanced Anti-ULBP6/2/5 Antibody, Restores NK Cell–Mediated Antitumor Immunity through NKG2D and FcγRIIIa Activation

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1. scibot 27 Mar 2025
  
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  DOI: 10.1158/2767-9764.CRC-24-0478
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11927390/
Dec 2024
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Dual BACH1 regulation by complementary SCF-type E3 ligases

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1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.cell.2024.11.006
  
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sciencedirect.com/science/article/pii/S0092867424013229
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Reactive oxygen species control protein degradation at the mitochondrial import gate

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1. scibot 06 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.11.004
  
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sciencedirect.com/science/article/pii/S1097276524009092
Aug 2024
bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com

Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti

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1. scibot 02 Aug 2024
  
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  DOI: 10.1186/s12915-022-01233-2
  
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bmcbiol.biomedcentral.com/articles/10.1186/s12915-022-01233-2
Jul 2024
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Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38

1
1. scibot 16 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114502
  
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sciencedirect.com/science/article/pii/S2211124724008313
Jan 2024
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Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46

1
1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.str.2023.12.001
  
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sciencedirect.com/science/article/pii/S0969212623004434
Dec 2023
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Electron counting with direct electron detectors in MicroED

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1. scibot 01 Dec 2023
  
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  DOI: 10.1016/j.str.2023.10.011
  
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sciencedirect.com/science/article/pii/S0969212623003969
Dec 2022
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Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding

1
1. scibot 13 Dec 2022
  
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  DOI: 10.1016/j.str.2022.11.008
  
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sciencedirect.com/science/article/pii/S0969212622004579
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes

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1. scibot 16 Nov 2022
  
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  RRID:SCR_015747
  
  DOI: 10.1016/j.immuni.2022.10.019
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9606073/
Mar 2022
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Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel

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1. scibot 04 Mar 2022
  
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  DOI: 10.1016/j.str.2022.02.005
  
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sciencedirect.com/science/article/pii/S0969212622000417
Feb 2022
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The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria

1
1. scibot 16 Feb 2022
  
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  DOI: 10.1016/j.celrep.2022.110367
  
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sciencedirect.com/science/article/pii/S2211124722000882
Sep 2021
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Structural basis and regulation of the reductive stress response

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1. scibot 25 Sep 2021
  
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  DOI: 10.1016/j.cell.2021.09.002
  
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sciencedirect.com/science/article/pii/S0092867421010497
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies

1
1. scibot 18 Sep 2021
  
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  DOI: 10.1016/j.celrep.2021.109760
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8423902/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Regulation of human mTOR complexes by DEPTOR

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1. scibot 18 Sep 2021
  
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  DOI: 10.7554/eLife.70871
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8439649/
Jul 2021
www.nature.com www.nature.com

Regulation of the endosomal SNX27-retromer by OTULIN

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1. scibot 30 Jul 2021
  
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  DOI: 10.1038/s41467-019-12309-z
  
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nature.com/articles/s41467-019-12309-z
www.pnas.org www.pnas.org

Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity

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1. scibot 29 Jul 2021
  
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  DOI: 10.1073/pnas.1906253116
  
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pnas.org/content/116/31/15505
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Cross-Reactive Donor-Specific CD8+ Tregs Efficiently Prevent Transplant Rejection

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1. scibot 28 Jul 2021
  
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  DOI: 10.1016/j.celrep.2019.11.106
  
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sciencedirect.com/science/article/pii/S2211124719316298
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RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer

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1. scibot 27 Jul 2021
  
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  Aimless
  
  DOI: 10.1016/j.ccell.2018.10.006
  
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sciencedirect.com/science/article/pii/S1535610818304720
Jun 2021
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B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV

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1. scibot 14 Jun 2021
  
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  DOI: 10.1016/j.cell.2021.04.032
  
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sciencedirect.com/science/article/pii/S0092867421005353
Apr 2021
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Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form

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1. scibot 14 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.108986
  
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sciencedirect.com/science/article/pii/S2211124721003004
www.cell.com www.cell.com

SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms

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1. scibot 08 Apr 2021
  
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  DOI: 10.1016/j.cell.2021.03.027
  
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cell.com/cell/fulltext/S0092-8674(21)00355-X
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site

1
1. scibot 24 Feb 2021
  
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  DOI: 10.7554/eLife.50661
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6957272/
Dec 2020
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Exploitation of Elevated Extracellular ATP to Specifically Direct Antibody to Tumor Microenvironment

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1. scibot 23 Dec 2020
  
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  DOI: 10.1016/j.celrep.2020.108542
  
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sciencedirect.com/science/article/pii/S221112472031531X
Nov 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cannabidiol interactions with voltage-gated sodium channels

1
1. scibot 12 Nov 2020
  
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  DOI: 10.7554/eLife.58593
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7641581/
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Structural model for differential cap maturation at growing microtubule ends

1
1. scibot 26 Sep 2020
  
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  DOI: 10.7554/eLife.50155
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7064335/
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A CLC-ec1 mutant reveals global conformational change and suggests a unifying mechanism for the CLC Cl–/H+ transport cycle

1
1. scibot 09 Sep 2020
  
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  DOI: 10.7554/eLife.53479
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7253180/
elifesciences.org elifesciences.org

The architecture of EMC reveals a path for membrane protein insertion

1
1. scibot 07 Sep 2020
  
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  DOI: 10.7554/eLife.57887
  
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elifesciences.org/articles/57887
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Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies

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1. scibot 07 Sep 2020
  
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  RRID:SCR_015747
  
  DOI: 10.1016/j.cell.2020.06.025
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7311918/
Jan 2020
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Identification and Characterization of Mutations in Ubiquitin Required for Non-covalent Dimer Formation

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1. scibot 13 Jan 2020
  
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  RRID:SCR_015747
  
  DOI: 10.1016/j.str.2019.06.008
  
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sciencedirect.com/science/article/pii/S0969212619302072
Nov 2018
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Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation

1
1. scibot 05 Nov 2018
  
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  Aimless
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S0969212618302922
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Analysis of Global and Site-Specific Radiation Damage in Cryo-EM

1
1. scibot 05 Nov 2018
  
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  RRID:SCR_015747
  
  Curator: @Jmenke
  
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Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor

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1. scibot 05 Nov 2018
  
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Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 Antibodies

1
1. scibot 05 Nov 2018
  
  in Public
  
  AIMLESS
  
  Curator: @evieth
  
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Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:SCR_015747
  
  Curator: @evieth
  
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europepmc.org europepmc.org

A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants

1
1. scibot 05 Nov 2018
  
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  RRID:SCR_015747
  
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europepmc.org/articles/PMC5655547/