253 Matching Annotations
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  3. Aug 2025
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    LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development
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    sciencedirect.com/science/article/pii/S2666979X25002356
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    Transient gene melting governs the timing of oligodendrocyte maturation
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    Genetic and Epigenetic Reprogramming of Transposable Elements Drives ecDNA-Mediated Metastatic Prostate Cancer
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    biorxiv.org/content/10.1101/2025.08.08.668693v1
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    Interplay of YEATS2 and GCDH regulates histone crotonylation and drives EMT in head and neck cancer
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    NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers
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    Distinct specificity and functions of PRC2 subcomplexes in human stem cells and cardiac differentiation
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    cell.com/iscience/abstract/S2589-0042(25)01529-9
  11. Jul 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiomics uncovers the epigenomic and transcriptomic response to viral and bacterial stimulation in turbot
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    TAF1 is required for fetal but not adult hematopoiesis in mice
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    The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
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    Enhancer Hijacking Discovery in Acute Myeloid Leukemia by Pyjacker Identifies MNX1 Activation via Deletion 7q
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  17. Jun 2025
  18. elifesciences.org elifesciences.org
    IDH1 regulates human erythropoiesis by eliciting chromatin state reprogramming
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    elifesciences.org/articles/100406
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    C-terminal binding protein 2 interacts with JUNB to control macrophage inflammation
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    A hexamer tandem repeat RNA embedded within an SVA retrotransposon drives R-loop formation and neurodegeneration
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    Satb1 directs the differentiation of TH17 cells through suppression of IL-2 expression
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    SpatialSNV: A novel method for identifying and analyzing spatially resolved SNVs in tumor microenvironments
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  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expression
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  25. May 2025
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    Mediator regulates transcriptional termination through crosstalk with pre-mRNA 3′ end processing factors
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    The human proteome with direct physical access to DNA
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    MCRS1 sensitizes T cell–dependent immunotherapy by augmenting MHC-I expression in solid tumors
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    A tumour necrosis factor-α responsive cryptic promoter drives overexpression of the human endogenous retrovirus ERVK-7
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    Transcription factor cooperativity at a GATA3 tandem DNA sequence determines oncogenic enhancer-mediated activation
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  32. Apr 2025
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia
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  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Treacle’s ability to form liquid-like phase condensates is essential for nucleolar fibrillar center assembly, efficient rRNA transcription and processing, and rRNA gene repair
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    Intestinal secretory differentiation reflects niche-driven phenotypic and epigenetic plasticity of a common signal-responsive terminal cell
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  36. Mar 2025
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    Orchestration of pluripotent stem cell genome reactivation during mitotic exit
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  40. Feb 2025
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    Pcf11/Spt5 condensates stall RNA polymerase II to facilitate termination and piRNA-guided heterochromatin formation
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  43. Jan 2025
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    Nucleosomal asymmetry shapes histone mark binding and promotes poising at bivalent domains
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  49. Dec 2024
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    3D chromatin hubs as regulatory units of identity and survival in human acute leukemia
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    ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF
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    Functional annotation of regulatory elements in rainbow trout uncovers roles of the epigenome in genetic selection and genome evolution
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  59. Nov 2024
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    ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin
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    Astrocyte allocation during brain development is controlled by Tcf4-mediated fate restriction
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  64. Oct 2024
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    HOXDeRNA activates a cancerous transcription program and super enhancers via genome-wide binding
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    H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone
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  67. Sep 2024
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    Multiple direct and indirect roles of the Paf1 complex in transcription elongation, splicing, and histone modifications
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    Detecting Small Cell Transformation in Patients with Advanced EGFR Mutant Lung Adenocarcinoma through Epigenomic cfDNA Profiling
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  70. Aug 2024
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    Characterizing Relationships between T-cell Inflammation and Outcomes in Patients with High-Risk Neuroblastoma According to Mesenchymal and Adrenergic Signatures
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    Members of an array of zinc-finger proteins specify distinct Hox chromatin boundaries
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    HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability
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  74. Jul 2024
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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    Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
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    The primitive endoderm supports lineage plasticity to enable regulative development
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    The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1
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    science.org/doi/10.1126/sciadv.adk1296
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    ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma
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    The Effect of Exposure to Neighborhood Violence on Glucocorticoid Receptor Signaling in Lung Tumors
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    The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1
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  82. Jun 2024
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    p53 gain-of-function mutation induces metastasis via Brd4-dependent Csf-1 expression
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  84. May 2024
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    Reciprocal conversion between annual and polycarpic perennial flowering behavior in the Brassicaceae
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    ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF
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    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
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    Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation
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    The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex
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    MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons
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  91. Apr 2024
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    A senescence restriction point acting on chromatin integrates oncogenic signals
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  93. Mar 2024
  94. link.springer.com link.springer.com
    From degraded to deciphered: ATAC-seq’s application potential in forensic diagnosis
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    link.springer.com/article/10.1007/s00414-024-03206-2
  95. Feb 2024
  96. 52.53.155.43 52.53.155.43
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  97. www.biorxiv.org www.biorxiv.org
    A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer
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    biorxiv.org/content/10.1101/2023.12.10.570854v1
  98. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-023-03161-y
  99. Jan 2024
  100. www.nature.com www.nature.com
    Cell-type-directed design of synthetic enhancers
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    nature.com/articles/s41586-023-06936-2
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function
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    ncbi.nlm.nih.gov/pmc/articles/PMC10769259/
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    Inherited blood cancer predisposition through altered transcription elongation
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    Temporal landscape of mitochondrial proteostasis governed by the UPRmt
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    science.org/doi/10.1126/sciadv.adh8228
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    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
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    Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation
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    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
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  220. Sep 2021
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