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Jun 2025
www.nature.com www.nature.com

Structural basis of GluK2 kainate receptor activation by a partial agonist

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1. scibot 11 Jun 2025
  
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  DOI: 10.1038/s41594-025-01566-w
  
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nature.com/articles/s41594-025-01566-w
May 2025
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Structural mechanisms of PIP2 activation and SEA0400 inhibition in human cardiac sodium-calcium exchanger NCX1

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1. scibot 29 May 2025
  
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  DOI: 10.7554/eLife.105396
  
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elifesciences.org/articles/105396
Aug 2024
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Mechanism of Ca2+ transport by ferroportin - ProQuest

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  DOI: 10.7554/eLife.82947
  
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proquest.com/docview/2771288630
Nov 2023
www.cell.com www.cell.com

The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus

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1. scibot 17 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113366
  
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cell.com/cell-reports/fulltext/S2211-1247(23)01378-5
Oct 2023
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A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response

2
1. scibot 20 Oct 2023
  
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  DOI: 10.1038/s41556-023-01248-z
  
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2. scibot 20 Oct 2023
  
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  DOI: 10.1038/s41556-023-01248-z
  
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nature.com/articles/s41556-023-01248-z
Aug 2023
52.53.155.43 52.53.155.43

EMBO Reports - 2023 - Jiang-html.html

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  DOI: 10.15252/embr.202356864
  
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52.53.155.43/72eed5338814ac6922d23d3395f365b4e68799b2/EMBO Reports - 2023 - Jiang-html.html
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mechanism of Ca2+ transport by ferroportin

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ncbi.nlm.nih.gov/pmc/articles/PMC9883014/
Jan 2023
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Nucleosome dyad determines the H1 C-terminus collapse on distinct DNA arms

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1. scibot 07 Jan 2023
  
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  DOI: 10.1016/j.str.2022.12.005
  
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sciencedirect.com/science/article/pii/S0969212622004919
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The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions

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  DOI: 10.1016/j.celrep.2022.111902
  
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sciencedirect.com/science/article/pii/S2211124722018010
Oct 2022
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A step-by-step protocol for capturing conformational snapshots of ligand gated ion channels by single-particle cryo-EM

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1. scibot 01 Oct 2022
  
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  DOI: 10.1016/j.xpro.2022.101732
  
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sciencedirect.com/science/article/pii/S2666166722006128
Jul 2022
www.pnas.org www.pnas.org

In situ architecture of the lipid transport protein VPS13C at ER–lysosome membrane contacts

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1. scibot 27 Jul 2022
  
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  DOI: 10.1073/pnas.2203769119
  
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pnas.org/doi/10.1073/pnas.2203769119
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Conserved structural elements specialize ATAD1 as a membrane protein extraction machine

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1. scibot 14 Jul 2022
  
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  DOI: 10.7554/eLife.73941
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9273213/
Jun 2022
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Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex

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1. scibot 10 Jun 2022
  
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  DOI: 10.1016/j.cell.2022.04.016
  
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sciencedirect.com/science/article/pii/S0092867422004639
Mar 2022
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Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB

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1. scibot 06 Mar 2022
  
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  DOI: 10.1016/j.str.2022.02.007
  
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sciencedirect.com/science/article/pii/S0969212622000430
Oct 2021
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Pan-ebolavirus protective therapy by two multifunctional human antibodies

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1. scibot 29 Oct 2021
  
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  DOI: 10.1016/j.cell.2021.09.035
  
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sciencedirect.com/science/article/pii/S009286742101165X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Structural characterization of NrnC identifies unifying features of dinucleotidases

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1. scibot 08 Oct 2021
  
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  DOI: 10.7554/eLife.70146
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8492067/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells

1
1. scibot 02 Oct 2021
  
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  DOI: 10.7554/eLife.71474
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8480983/
Sep 2021
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Structural snapshots of TRPV1 reveal mechanism of polymodal functionality

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1. scibot 08 Sep 2021
  
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  DOI: 10.1016/j.cell.2021.08.012
  
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sciencedirect.com/science/article/pii/S009286742100982X
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core

1
1. scibot 05 Aug 2021
  
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  DOI: 10.7554/eLife.37688
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6237438/
elifesciences.org elifesciences.org

Structure and analysis of nanobody binding to the human ASIC1a ion channel

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1. scibot 05 Aug 2021
  
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  DOI: 10.7554/eLife.67115
  
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elifesciences.org/articles/67115
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Structures of translationally inactive mammalian ribosomes

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  DOI: 10.7554/eLife.40486
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6226290/
Jul 2021
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High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms

1
1. scibot 31 Jul 2021
  
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  DOI: 10.7554/eLife.43075
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6365055/
elifesciences.org elifesciences.org

Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands

1
1. scibot 30 Jul 2021
  
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  DOI: 10.7554/eLife.47650
  
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elifesciences.org/articles/47650
elifesciences.org elifesciences.org

A contractile injection system stimulates tubeworm metamorphosis by translocating a proteinaceous effector

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1. scibot 30 Jul 2021
  
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  DOI: 10.7554/eLife.46845
  
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elifesciences.org/articles/46845
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Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability

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1. scibot 29 Jul 2021
  
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  DOI: 10.1016/j.immuni.2019.10.008
  
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sciencedirect.com/science/article/pii/S1074761319304522
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Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins

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1. scibot 28 Jul 2021
  
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  DOI: 10.1016/j.chom.2019.05.004
  
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sciencedirect.com/science/article/pii/S1931312819302495
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Structures of translationally inactive mammalian ribosomes

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1. scibot 28 Jul 2021
  
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  DOI: 10.7554/eLife.40486
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6226290/
elifesciences.org elifesciences.org

Structural and functional characterization of an otopetrin family proton channel

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1. scibot 28 Jul 2021
  
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  DOI: 10.7554/eLife.46710
  
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elifesciences.org/articles/46710
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Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition

1
1. scibot 27 Jul 2021
  
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  DOI: 10.1016/j.str.2018.10.007
  
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sciencedirect.com/science/article/pii/S096921261830368X
May 2021
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Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP

1
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  DOI: 10.1016/j.molcel.2020.11.002
  
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sciencedirect.com/science/article/pii/S1097276520307802
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Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis

1
1. scibot 07 May 2021
  
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  DOI: 10.1016/j.molcel.2020.08.010
  
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sciencedirect.com/science/article/pii/S1097276520305530
Feb 2021
www.cell.com www.cell.com

Mimicry of Canonical Translation Elongation Underlies Alanine Tail Synthesis in RQC

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  DOI: 10.1016/j.molcel.2020.11.001
  
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cell.com/molecular-cell/fulltext/S1097-2765(20)30779-6
Jan 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Structure of bacterial phospholipid transporter MlaFEDB with substrate bound

1
1. scibot 13 Jan 2021
  
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  DOI: 10.7554/eLife.62518
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7790496/
Dec 2020
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The Halastavi árva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism

1
1. scibot 13 Dec 2020
  
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  DOI: 10.1016/j.celrep.2020.108476
  
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sciencedirect.com/science/article/pii/S2211124720314650
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A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide

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1. scibot 07 Dec 2020
  
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  DOI: 10.1016/j.celrep.2020.108428
  
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cell.com/cell-reports/fulltext/S2211-1247(20)31417-0
Nov 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Structural basis of αE-catenin–F-actin catch bond behavior

1
1. scibot 13 Nov 2020
  
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  RRID:SCR_016500
  
  DOI: 10.7554/eLife.60878
  
  Resource: GCTF (RRID:SCR_016500)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7588230/
Sep 2020
elifesciences.org elifesciences.org

Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction

1
1. scibot 26 Sep 2020
  
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  RRID:SCR_016500
  
  DOI: 10.7554/eLife.54031
  
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An ER translocon for multi-pass membrane protein biogenesis

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1. scibot 25 Sep 2020
  
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  RRID:SCR_016500
  
  DOI: 10.7554/eLife.56889
  
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elifesciences.org elifesciences.org

Cryo-EM structures of S-OPA1 reveal its interactions with membrane and changes upon nucleotide binding

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1. scibot 23 Sep 2020
  
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  RRID:SCR_016500
  
  DOI: 10.7554/eLife.50294
  
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Mechanical inhibition of isolated Vo from V/A-ATPase for proton conductance

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1. scibot 15 Sep 2020
  
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  RRID:SCR_016500
  
  DOI: 10.7554/eLife.56862
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7367684/
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Cryo-EM Reveals Integrin-Mediated TGF-β Activation without Release from Latent TGF-β

1
1. scibot 14 Sep 2020
  
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  RRID:SCR_016500
  
  DOI: 10.1016/j.cell.2019.12.030
  
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Cryo-EM structure of VASH1-SVBP bound to microtubules

1
1. scibot 09 Sep 2020
  
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  RRID:SCR_016500
  
  DOI: 10.7554/eLife.58157
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7449697/
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The His-Gly motif of acid-sensing ion channels resides in a reentrant ‘loop’ implicated in gating and ion selectivity

1
1. scibot 09 Sep 2020
  
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  RRID:SCR_016500
  
  DOI: 10.7554/eLife.56527
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7308080/
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Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization

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1. scibot 06 Sep 2020
  
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  RRID:SCR_016500
  
  DOI: 10.1016/j.immuni.2020.01.001
  
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Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism

1
1. scibot 06 Sep 2020
  
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  RRID:SCR_016500
  
  DOI: 10.7554/eLife.56185
  
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Structural basis of substrate recognition by a polypeptide processing and secretion transporter

1
1. scibot 06 Sep 2020
  
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  RRID:SCR_016500
  
  DOI: 10.7554/eLife.51492
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6959990/
Jan 2020
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Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_016500
  
  DOI: 10.1016/j.chom.2019.10.002
  
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Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_016500
  
  DOI: 10.7554/eLife.44707
  
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Regulatory switch at the cytoplasmic interface controls TRPV channel gating

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_016500
  
  DOI: 10.7554/eLife.47746
  
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Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_016500
  
  DOI: 10.1016/j.chom.2019.04.011
  
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Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_016500
  
  DOI: 10.1016/j.celrep.2019.08.052
  
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sciencedirect.com/science/article/pii/S2211124719311003
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Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_016500
  
  DOI: 10.7554/eLife.45779
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6544438/
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High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms

1
1. scibot 13 Jan 2020
  
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  RRID:SCR_016500
  
  DOI: 10.7554/eLife.43075
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6365055/
Nov 2018
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Structure of the human epithelial sodium channel by cryo-electron microscopy

1
1. scibot 05 Nov 2018
  
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  SCR_016500
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6197857/
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Human SEIPIN Binds Anionic Phospholipids

1
1. scibot 05 Nov 2018
  
  in Public
  
  Gctf
  
  Curator: @Jmenke
  
  Resource used:
  
  (GCTF, RRID:SCR_016500)
  
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sciencedirect.com/science/article/pii/S1534580718307391