66 Matching Annotations
  1. Jul 2026
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    Double-ring assembly of mpox virus I3L reveals an unconventional mechanism for ssDNA engagement
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    sciencedirect.com/science/article/pii/S2211124726007370
  3. Apr 2026
  4. www.cell.com www.cell.com
    The Erlin1/2 complex is a dynamic scaffold for membrane microdomain assembly on the endoplasmic reticulum
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    cell.com/molecular-cell/abstract/S1097-2765(26)00157-7
  5. Mar 2026
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    A correlative workflow for synaptic imaging by cryo-electron tomography
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    sciencedirect.com/science/article/pii/S0969212626000596
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structural basis of Cas8-independent Cas3 recruitment in Type I-F2 CRISPR–Cas
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    pmc.ncbi.nlm.nih.gov/articles/PMC12956352/
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    Metabolite-gated vascular contractility switch: OXGR1 activation mechanism enables agonist therapy for rosacea erythema
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    sciencedirect.com/science/article/pii/S0092867426001649
  9. Jan 2026
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    Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex
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    sciencedirect.com/science/article/pii/S0092867425014187
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    Mechanisms of HSV-1 helicase-primase inhibition and replication fork complex assembly
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    sciencedirect.com/science/article/pii/S0092867425013765
  12. Oct 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular dynamics of the matrisome across sea anemone life history
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    pmc.ncbi.nlm.nih.gov/articles/PMC12549020/
  14. Aug 2025
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    The HIV-1 nuclear export complex reveals the role of RNA in CRM1 cargo recognition
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    sciencedirect.com/science/article/pii/S1097276525006161
  16. Jun 2025
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    Structural insights into the biotechnologically relevant reversible NADPH-oxidizing NiFe-hydrogenase from P. furiosus
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    sciencedirect.com/science/article/pii/S0969212625002151
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    Structural basis of GluK2 kainate receptor activation by a partial agonist
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    nature.com/articles/s41594-025-01566-w
  19. Jan 2025
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    Structural and functional analysis of the Nipah virus polymerase complex
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    sciencedirect.com/science/article/pii/S009286742401434X
  21. Nov 2024
  22. www.biorxiv.org www.biorxiv.org
    Inhibition of Parkinson’s Disease-related LRRK2 by type-I and type-II kinase inhibitors: activity and structures
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    biorxiv.org/content/10.1101/2023.09.07.556689v1
  23. Sep 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures reveal gatekeeping of the mitochondrial Ca2+ uniporter by MICU1-MICU2
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    ncbi.nlm.nih.gov/pmc/articles/PMC7434445/
  25. elifesciences.org elifesciences.org
    Cryo-EM structure of the lysosomal chloride-proton exchanger CLC-7 in complex with OSTM1
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    elifesciences.org/articles/59555
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gating and selectivity mechanisms for the lysosomal K+ channel TMEM175
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    ncbi.nlm.nih.gov/pmc/articles/PMC7141809/
  27. Jun 2024
  28. www.sciencedirect.com www.sciencedirect.com
    A designed ankyrin-repeat protein that targets Parkinson’s disease-associated LRRK2
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    sciencedirect.com/science/article/pii/S0021925824019707
  29. www.cell.com www.cell.com
    POT1 recruits and regulates CST-Polα/primase at human telomeres
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    cell.com/cell/fulltext/S0092-8674(24)00493-8
  30. Apr 2024
  31. www.cell.com www.cell.com
    Structural basis of ligand specificity and channel activation in an insect gustatory receptor
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    cell.com/cell-reports/fulltext/S2211-1247(24)00363-2
  32. Nov 2023
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    Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa
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    sciencedirect.com/science/article/pii/S009286742301084X
  34. Aug 2023
  35. 52.53.155.43 52.53.155.43
    EMBO Reports - 2023 - Jiang-html.html
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    52.53.155.43/72eed5338814ac6922d23d3395f365b4e68799b2/EMBO Reports - 2023 - Jiang-html.html
  36. Jul 2023
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor
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    ncbi.nlm.nih.gov/pmc/articles/PMC10338036/
  38. Jun 2023
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    Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment
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    sciencedirect.com/science/article/pii/S1097276523004203
  40. Mar 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster
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    ncbi.nlm.nih.gov/pmc/articles/PMC9977279/
  42. Jan 2023
  43. www.sciencedirect.com www.sciencedirect.com
    The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions
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    sciencedirect.com/science/article/pii/S2211124722018010
  44. Dec 2022
  45. www.nature.com www.nature.com
    Structural basis for Parkinson’s disease-linked LRRK2’s binding to microtubules
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    nature.com/articles/s41594-022-00863-y
  46. Mar 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Structural basis for catalyzed assembly of the Sonic hedgehog–Patched1 signaling complex
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    sciencedirect.com/science/article/pii/S1534580722000740
  48. Nov 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1
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    sciencedirect.com/science/article/pii/S0969212621003725
  50. Oct 2021
  51. www.cell.com www.cell.com
    Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells
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    cell.com/cell-reports/fulltext/S2211-1247(21)01347-4
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8480983/
  53. Sep 2021
  54. elifesciences.org elifesciences.org
    Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome
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    elifesciences.org/articles/71420
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of human mTOR complexes by DEPTOR
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    ncbi.nlm.nih.gov/pmc/articles/PMC8439649/
  56. Aug 2021
  57. elifesciences.org elifesciences.org
    Functional development of a V3/glycan-specific broadly neutralizing antibody isolated from a case of HIV superinfection
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    elifesciences.org/articles/68110
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8357420/
  59. Jul 2021
  60. elifesciences.org elifesciences.org
    Mechanism of pharmacochaperoning in a mammalian KATP channel revealed by cryo-EM
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    elifesciences.org/articles/46417
  61. www.sciencedirect.com www.sciencedirect.com
    Structure of the Mechanosensitive Channel MscS Embedded in the Membrane Bilayer
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    sciencedirect.com/science/article/pii/S0022283619304279
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core
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    ncbi.nlm.nih.gov/pmc/articles/PMC6237438/
  63. May 2021
  64. www.sciencedirect.com www.sciencedirect.com
    The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain
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    sciencedirect.com/science/article/pii/S0969212620302112
  65. www.sciencedirect.com www.sciencedirect.com
    Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis
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    sciencedirect.com/science/article/pii/S1097276520305530
  66. Apr 2021
  67. www.sciencedirect.com www.sciencedirect.com
    Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex
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    sciencedirect.com/science/article/pii/S0969212621001192
  68. elifesciences.org elifesciences.org
    Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor
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    elifesciences.org/articles/66097
  69. Mar 2021
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A pentameric protein ring with novel architecture is required for herpesviral packaging
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    ncbi.nlm.nih.gov/pmc/articles/PMC7889075/
  71. www.sciencedirect.com www.sciencedirect.com
    Structural basis for self-cleavage prevention by tag:anti-tag pairing complementarity in type VI Cas13 CRISPR systems
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    sciencedirect.com/science/article/pii/S1097276520309540
  72. Feb 2021
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atomic structure of a mitochondrial complex I intermediate from vascular plants
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    ncbi.nlm.nih.gov/pmc/articles/PMC7447434/
  74. Jan 2021
  75. elifesciences.org elifesciences.org
    Atomic structures of respiratory complex III 2, complex IV, and supercomplex III 2-IV from vascular plants
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    elifesciences.org/articles/62047
  76. Dec 2020
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large domain movements through the lipid bilayer mediate substrate release and inhibition of glutamate transporters
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    ncbi.nlm.nih.gov/pmc/articles/PMC7682989/
  78. Nov 2020
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates
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    ncbi.nlm.nih.gov/pmc/articles/PMC7652416/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of αE-catenin–F-actin catch bond behavior
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    ncbi.nlm.nih.gov/pmc/articles/PMC7588230/
  81. Oct 2020
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular mechanism for direct actin force-sensing by α-catenin
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    ncbi.nlm.nih.gov/pmc/articles/PMC7588232/
  83. Sep 2020
  84. elifesciences.org elifesciences.org
    Cryo-EM structures of S-OPA1 reveal its interactions with membrane and changes upon nucleotide binding
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    elifesciences.org/articles/50294
  85. elifesciences.org elifesciences.org
    Molecular principles of assembly, activation, and inhibition in epithelial sodium channel
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    elifesciences.org/articles/59038
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemical and structural investigation of the paroxetine-human serotonin transporter complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC7470834/
  87. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM Reveals Integrin-Mediated TGF-β Activation without Release from Latent TGF-β
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    sciencedirect.com/science/article/pii/S0092867419313923
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    Structure and activation mechanism of the BBSome membrane protein trafficking complex
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    elifesciences.org/articles/53322
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limited dishevelled/Axin oligomerization determines efficiency of Wnt/β-catenin signal transduction
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    ncbi.nlm.nih.gov/pmc/articles/PMC7200158/
  90. elifesciences.org elifesciences.org
    Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism
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    elifesciences.org/articles/56185
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies
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    ncbi.nlm.nih.gov/pmc/articles/PMC7311918/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of substrate recognition by a polypeptide processing and secretion transporter
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    ncbi.nlm.nih.gov/pmc/articles/PMC6959990/
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate
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    ncbi.nlm.nih.gov/pmc/articles/PMC7112951/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atomic structure of a mitochondrial complex I intermediate from vascular plants
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    ncbi.nlm.nih.gov/pmc/articles/PMC7447434/
  95. Jan 2020
  96. elifesciences.org elifesciences.org
    Regulation of Eag1 gating by its intracellular domains
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    elifesciences.org/articles/49188
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    Multisystem Proteinopathy Mutations in VCP/p97 Increase NPLOC4·UFD1L Binding and Substrate Processing
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    sciencedirect.com/science/article/pii/S096921261930317X
  98. www.cell.com www.cell.com
    Capsid Structure of a Freshwater Cyanophage Siphoviridae Mic1
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    cell.com/structure/abstract/S0969-2126(19)30235-7
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    Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State
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    sciencedirect.com/science/article/pii/S0969212619303545
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6519985/