92 Matching Annotations
  1. Aug 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A near-complete genome assembly of the bearded dragon Pogona vitticeps provides insights into the origin of Pogona sex chromosomes
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12360845/
  3. Jul 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The genome of Hippophae salicifolia provides new insights into the sexual differentiation of sea buckthorn
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12218201/
  5. Jun 2025
  6. dx.doi.org dx.doi.org
    PISAD: reference-free intraspecies sample anomalies detection tool based on k-mer counting
    1
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    dx.doi.org/10.1093/gigascience/giaf061
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chromosome-level genome assembly of the lemon sole, Microstomus kitt (Pleuronectiformes: Pleuronectidae)
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12135936/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chromosome-level genome assembly and methylome profile yield insights for the conservation of endangered loggerhead sea turtles
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12143204/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chromosome-level reference genome for the medically important Arabian horned viper (Cerastes gasperettii)
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12143202/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chromosome-level genome assembly of Pinus massoniana provides insights into conifer adaptive evolution
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12122422/
  11. May 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Repeatome diversity in sea anemone genomics (Cnidaria: Actiniaria) based on the Actiniaria-REPlib library
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12070523/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chromosome-scale assemblies of three Ormosia species: repetitive sequences distribution and structural rearrangement
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12083454/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The haplotype-resolved T2T genome for Bauhinia × blakeana sheds light on the genetic basis of flower heterosis
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12012898/
  15. Apr 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome assembly and annotation of Acropora pulchra from Mo’orea French Polynesia
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11985253/
  17. Mar 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A telomere-to-telomere phased genome of an octoploid strawberry reveals a receptor kinase conferring anthracnose resistance
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11899574/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Draft genome of the endangered visayan spotted deer (Rusa alfredi), a Philippine endemic species
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11876970/
  20. Feb 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genomic evidence for hybridization and introgression between blue peafowl and endangered green peafowl and molecular foundation of leucistic plumage of blue peafowl
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11835448/
  22. Jan 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae: Phoxinus phoxinus) provide evidence of haplotype diversity
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11775470/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The genome of the sapphire damselfish Chrysiptera cyanea: a new resource to support further investigation of the evolution of Pomacentrids
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11711634/
  25. Dec 2024
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    De novo assembly and characterization of a highly degenerated ZW sex chromosome in the fish Megaleporinus macrocephalus
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11590113/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Construction and analysis of telomere-to-telomere genomes for 2 sweet oranges: Longhuihong and Newhall (Citrus sinensis)
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11590112/
  28. dx.doi.org dx.doi.org
    A first look at the genome structure of hexaploid “Mitcham” peppermint (Mentha × piperita L.)
    1
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    dx.doi.org/10.1093/g3journal/jkae195
  29. Nov 2024
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chromosome-level genome assembly and annotation of the crested gecko, Correlophus ciliatus, a lizard incapable of tail regeneration
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11558660/
  31. Sep 2024
  32. www.biorxiv.org www.biorxiv.org
    A near-complete genome assembly of the bearded dragon Pogona vitticeps provides insights into the origin of Pogona sex chromosomes
    1
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    biorxiv.org/content/10.1101/2024.09.05.611321v1
  33. Aug 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome report: First reference genome of Vaccinium floribundum Kunth, an emblematic Andean species
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11304950/
  35. Jul 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    De-novo long-read genome assembly and annotation of the luna moth (Actias luna) fully resolves repeat-rich silk genes
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11258402/
  37. Jun 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The telomere-to-telomere (T2T) genome of Peucedanum praeruptorum Dunn provides insights into the genome evolution and coumarin biosynthesis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11152176/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A haplotype-resolved chromosome-level assembly and annotation of European hazelnut (C. avellana cv. Jefferson) provides insight into mechanisms of eastern filbert blight resistance
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11152071/
  40. May 2024
  41. www.biorxiv.org www.biorxiv.org
    A first look at the genome structure of hexaploid ‘Black Mitcham’ peppermint (Mentha piperita L.)
    2
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    biorxiv.org/content/10.1101/2024.03.15.585188v1
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome assembly of the edible jelly fungus Dacryopinax spathularia (Dacrymycetaceae)
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11066560/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromosome-level genome assembly of the common chiton, Liolophura japonica (Lischke, 1873)
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11068029/
  44. Apr 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Whole genome assembly and annotation of the King Angelfish (Holacanthus passer) gives insight into the evolution of marine fishes of the Tropical Eastern Pacific
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10973836/
  46. Mar 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromosome-level genome of the poultry shaft louse Menopon gallinae provides insight into the host-switching and adaptive evolution of parasitic lice
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10904027/
  48. Feb 2024
  49. dx.doi.org dx.doi.org
    Long read genome assembly of Automeris io (Lepidoptera: Saturniidae) an emerging model for the evolution of deimatic displays
    1
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    dx.doi.org/10.1093/g3journal/jkad292
  50. Jan 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Near chromosome-level and highly repetitive genome assembly of the snake pipefish Entelurus aequoreus (Syngnathiformes: Syngnathidae)
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10795108/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evolutionary genomics of three agricultural pest moths reveals rapid evolution of host adaptation and immune-related genes
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10759296/
  53. Nov 2023
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A reference assembly for the legume cover crop hairy vetch (Vicia villosa)
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10659084/
  55. Oct 2023
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The chromosome-level genome of Chinese praying mantis Tenodera sinensis (Mantodea: Mantidae) reveals its biology as a predator
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10600911/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A chromosome-level assembly supports genome-wide investigation of the DMRT gene family in the golden mussel (Limnoperna fortunei)
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10541798/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Construction and analysis of the chromosome-level haplotype-resolved genomes of two Crassostrea oyster congeners: Crassostrea angulata and Crassostrea gigas
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10546077/
  59. Sep 2023
  60. www.biorxiv.org www.biorxiv.org
    A haplotype-resolved chromosome-level assembly and annotation of European hazelnut (C. avellana cv. Jefferson) provides insight into mechanisms of eastern filbert blight resistance
    1
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    biorxiv.org/content/10.1101/2023.09.21.558899v1
  61. Aug 2023
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromosome-scale assembly of the yellow mealworm genome
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10445852/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Haplogenome assembly reveals structural variation in Eucalyptus interspecific hybrids
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10460159/
  64. Jul 2023
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of sex chromosomes and primary sex ratio in the small hive beetle, a worldwide parasite of honey bees
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10367126/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome assembly of the hybrid grapevine Vitis ‘Chambourcin’
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10318349/
  67. May 2023
  68. academic.oup.com academic.oup.com
    A high-quality, long-read genome assembly of the whitelined sphinx moth (Lepidoptera: Sphingidae: Hyles lineata) shows highly conserved melanin synthesis pathway genes
    1
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    academic.oup.com/g3journal/advance-article/doi/10.1093/g3journal/jkad090/7147210
  69. Apr 2023
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular mechanisms underlying hematophagia revealed by comparative analyses of leech genomes
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10087013/
  71. Mar 2023
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improvements to the Gulf pipefish Syngnathus scovelli genome
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10038202/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A highly contiguous, scaffold-level nuclear genome assembly for the fever tree (Cinchona pubescens Vahl) as a novel resource for Rubiaceae research
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10027117/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromosome-level genome assembly of a benthic associated Syngnathiformes species: the common dragonet, Callionymus lyra
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9631949/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A phased, chromosome-scale genome of ‘Honeycrisp’ apple (Malus domestica)
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9693968/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A draft genome assembly of the eastern banjo frog Limnodynastes dumerilii dumerilii (Anura: Limnodynastidae)
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9632003/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromosome-level assembly of the common vetch (Vicia sativa) reference genome
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9650280/
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long-read HiFi sequencing correctly assembles repetitive heavy fibroin silk genes in new moth and caddisfly genomes
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9693786/
  79. 52.53.155.43 52.53.155.43
    A chromosome-scale reference genome assembly of the great sand eel, Hyperoplus lanceolatus
    1
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    52.53.155.43/c66fa9b2ea7c129831e4f3a5d878c6edc0d7a347/esad003-html.html
  80. Feb 2023
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome assembly of Musa beccarii shows extensive chromosomal rearrangements and genome expansion during evolution of Musaceae genomes
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9941839/
  82. www.sciencedirect.com www.sciencedirect.com
    A chromosome-level genome assembly of Ostrea denselamellosa provides initial insights into its evolution
    1
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    sciencedirect.com/science/article/pii/S0888754323000265
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromosome-level genome and the identification of sex chromosomes in Uloborus diversus
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9912274/
  84. academic.oup.com academic.oup.com
    Chromosome-level genome assembly of goose provides insight into the adaptation and growth of local goose breeds
    1
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    academic.oup.com/gigascience/article/doi/10.1093/gigascience/giad003/7025323
  85. Jan 2023
  86. www.nature.com www.nature.com
    A chromosome-level genome assembly of Plantago ovata
    1
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    nature.com/articles/s41598-022-25078-5
  87. www.biorxiv.org www.biorxiv.org
    A chromosome-scale assembly for tetraploid sour cherry (Prunus cerasus L.) ‘Montmorency’ identifies three distinct ancestral Prunus genomes
    1
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    biorxiv.org/content/10.1101/2023.01.10.523438v1
  88. Dec 2022
  89. academic.oup.com academic.oup.com
    A chromosome-length genome assembly and annotation of blackberry (Rubus argutus, cv. “Hillquist”)
    1
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    academic.oup.com/g3journal/advance-article/doi/10.1093/g3journal/jkac289/6798616
  90. Nov 2022
  91. academic.oup.com academic.oup.com
    Capparis spinosa var. herbacea genome provides the first genomic instrument for a diversity and evolution study of the Capparaceae family
    1
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    academic.oup.com/gigascience/article/doi/10.1093/gigascience/giac106/6780308
  92. Sep 2022
  93. academic.oup.com academic.oup.com
    Comparative genome and evolution analyses of an endangered stony coral species Dendrophyllia cribrosa near Dokdo Islands in the East Sea
    1
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    academic.oup.com/gbe/article/14/9/evac132/6677079
  94. Jul 2022
  95. academic.oup.com academic.oup.com
    Chromosome-Level Genome Assembly of the Butter Clam Saxidomus purpuratus
    1
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    academic.oup.com/gbe/article/14/7/evac106/6650251
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A chromosome-level genome of the booklouse, Liposcelis brunnea, provides insight into louse evolution and environmental stress adaptation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9295366/
  97. 52.53.155.43 52.53.155.43
    A chromosome-scale genome assembly of the okapi (Okapia johnstoni)
    1
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    52.53.155.43/ca38f07792210b0253061a6791db53fa681aee2f/esac033-html.html
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromosome-level assembly and annotation of the blue catfish Ictalurus furcatus, an aquaculture species for hybrid catfish reproduction, epigenetics, and heterosis studies
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9270728/
  99. Jun 2022
  100. academic.oup.com academic.oup.com
    Genomes and demographic histories of the endangered Bretschneidera sinensis (Akaniaceae)
    1
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    academic.oup.com/gigascience/article/doi/10.1093/gigascience/giac050/6608505
  101. May 2022
  102. academic.oup.com academic.oup.com
    Chromosome‐level genome assembly of the black widow spider Latrodectus elegans illuminates composition and evolution of venom and silk proteins
    1
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    academic.oup.com/gigascience/article/doi/10.1093/gigascience/giac049/6593146
  103. f1000research.com f1000research.com
    F1000Research Article: The third international hackathon for applying insights into large-scale genomic composition to use cases in a wide range of organisms.
    1
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    f1000research.com/articles/11-530
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A chromosome-level reference genome of Ensete glaucum gives insight into diversity and chromosomal and repetitive sequence evolution in the Musaceae
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9055855/
  105. Mar 2022
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fully resolved assembly of Cryptosporidium parvum
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8848321/
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome size evolution in the diverse insect order Trichoptera
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8881205/
  108. Jan 2022
  109. academic.oup.com academic.oup.com
    Chromosome-level genome assembly of the shuttles hoppfish, Periophthalmus modestus
    1
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    academic.oup.com/gigascience/article/doi/10.1093/gigascience/giab089/6505119
  110. Dec 2021
  111. academic.oup.com academic.oup.com
    A high-resolution genome of an euryhaline and eurythermal rhinogoby (Rhinogobius similis Gill 1895)
    1
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    academic.oup.com/g3journal/advance-article/doi/10.1093/g3journal/jkab395/6430980
  112. Nov 2021
  113. gigabytejournal.com gigabytejournal.com
    Bicolor angelfish (Centropyge bicolor) provides the first chromosome-level genome of the Pomacanthidae family
    1
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    gigabytejournal.com/articles/32
  114. Oct 2021
  115. academic.oup.com academic.oup.com
    Chromosome-level genome assemblies of Channa argus and Channa maculata and comparative analysis of their temperature adaptability
    1
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    academic.oup.com/gigascience/article/10/10/giab070/6407244
  116. Jun 2021
  117. academic.oup.com academic.oup.com
    The genome of the venomous snail Lautoconus ventricosus sheds light on the origin of conotoxin diversity
    1
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    academic.oup.com/gigascience/article/10/5/giab037/6284011
  118. May 2021
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two high-quality de novo genomes from single ethanol-preserved specimens of tiny metazoans (Collembola)
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8138834/
  120. Apr 2021
  121. academic.oup.com academic.oup.com
    A chromosome-level genome assembly for the Pacific oyster Crassostrea gigas
    1
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    academic.oup.com/gigascience/article/10/3/giab020/6187865
  122. Mar 2021
  123. academic.oup.com academic.oup.com
    A chromosome‐level genome of the spider Trichonephila antipodiana reveals the genetic basis of its polyphagy and evidence of an ancient whole-genome duplication event
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    academic.oup.com/gigascience/article/10/3/giab016/6178709
  124. Jan 2021
  125. academic.oup.com academic.oup.com
    Comparison of long-read methods for sequencing and assembly of a plant genome
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    academic.oup.com/gigascience/article/9/12/giaa146/6042729
  126. Dec 2020
  127. academic.oup.com academic.oup.com
    Long-read assembly of the Brassica napus reference genome Darmor-bzh
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    academic.oup.com/gigascience/article/9/12/giaa137/6034787
  128. Nov 2020
  129. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Adaptive venom evolution and toxicity in octopods is driven by extensive novel gene formation, expansion, and loss
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    pubmed.ncbi.nlm.nih.gov/33175168/
  130. Sep 2020
  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The gene-rich genome of the scallop Pecten maximus
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    ncbi.nlm.nih.gov/pmc/articles/PMC7191990/
  132. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Construction of a chromosome-scale long-read reference genome assembly for potato
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    pubmed.ncbi.nlm.nih.gov/32964225/
  133. academic.oup.com academic.oup.com
    Generation of a chromosome-scale genome assembly of the insect-repellent terpenoid-producing Lamiaceae species, Callicarpa americana
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    academic.oup.com/gigascience/article/9/9/giaa093/5902285
  134. academic.oup.com academic.oup.com
    The chromosome-level draft genome of Dalbergia odorifera
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    academic.oup.com/gigascience/article/9/8/giaa084/5893771
  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A haplotype-resolved, de novo genome assembly for the wood tiger moth (Arctia plantaginis) through trio binning
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    ncbi.nlm.nih.gov/pmc/articles/PMC7433188/
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    Continuous chromosome-scale haplotypes assembled from a single interspecies F1 hybrid of yak and cattle
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    academic.oup.com/gigascience/article/9/4/giaa029/5815405
  137. Jan 2020
  138. academic.oup.com academic.oup.com
    The draft genome sequence of the spider Dysdera silvatica (Araneae, Dysderidae): A valuable resource for functional and evolutionary genomic studies in chelicerates
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    academic.oup.com/gigascience/article/8/8/giz099/5552235
  139. academic.oup.com academic.oup.com
    The draft nuclear genome assembly of Eucalyptus pauciflora: a pipeline for comparing de novo assemblies
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    academic.oup.com/gigascience/article/9/1/giz160/5694103
  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A haplotype-resolved draft genome of the European sardine (Sardina pilchardus)
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    ncbi.nlm.nih.gov/pmc/articles/PMC6528745/