136 Matching Annotations
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    GPSai: A Clinically Validated AI Tool for Tissue of Origin Prediction During Routine Tumor Profiling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12399951/
  3. Aug 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multidimensional Analysis of B7 homolog 3 (B7-H3) RNA Expression in Small-cell Lung Cancer Molecular Subtypes
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    Differential Efficacy of Bevacizumab and Erlotinib in Preclinical Models of Renal Medullary Carcinoma and Fumarate Hydratase–Deficient Renal Cell Carcinoma
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    Chevreul: an R bioconductor package for exploratory analysis of full-length single cell sequencing
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    pmc.ncbi.nlm.nih.gov/articles/PMC12320507/
  7. Jul 2025
  8. 52.53.155.43 52.53.155.43
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    TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice
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    cell.com/cell-stem-cell/fulltext/S1934-5909(25)00228-0
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    Deconstructing the common anteroposterior organisation of adult bilaterian guts
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    biorxiv.org/content/10.1101/2025.07.02.662275v1
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    The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
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    sciencedirect.com/science/article/pii/S1074761325002481
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    Dual inhibition of EGFR and PI3Kinase signaling in EGFR amplified triple negative breast cancer cells induces apoptosis and reduces tumor growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12157506/
  13. Jun 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    C-terminal binding protein 2 interacts with JUNB to control macrophage inflammation
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  15. May 2025
  16. 52.53.155.43 52.53.155.43
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    Complete Loss of PAX4 causes Transient Neonatal Diabetes in Humans
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  18. Apr 2025
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    The multi-level effect of chlorpyrifos during clownfish metamorphosis
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    sciencedirect.com/science/article/pii/S0303720725000863
  20. Mar 2025
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    Benchmarking short-read metagenomics tools for removing host contamination
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    academic.oup.com/gigascience/article/doi/10.1093/gigascience/giaf004/8045180
  22. Feb 2025
  23. aacrjournals.org aacrjournals.org
    Epigenome reprogramming through H3K27 and H3K4 trimethylation as a resistance mechanism to DNA methylation inhibition in BRAFV600E-mutated colorectal cancer
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    aacrjournals.org/clincancerres/article/30/22/5166/749574/Epigenome-Reprogramming-Through-H3K27-and-H3K4
  24. Jan 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Natural killer cell–mediated cytotoxicity shapes the clonal evolution of B cell leukaemia
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    Hypoxia drives the formation of lung micropapillary adenocarcinoma-like structure through hypoxia-inducible factor-1α
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    nature.com/articles/s41598-024-80280-x
  28. Dec 2024
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pathogenic mitochondrial DNA variants are associated with response to anti-VEGF therapy in ovarian cancer PDX models
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    pmc.ncbi.nlm.nih.gov/articles/PMC11657443/
  30. elifesciences.org elifesciences.org
    Control of 3′ splice site selection by the yeast splicing factor Fyv6
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    elifesciences.org/articles/100449
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    Lurbinectedin sensitizes PD-L1 blockade therapy by activating STING-IFN signaling in small-cell lung cancer
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    sciencedirect.com/science/article/pii/S2666379124006232
  32. Nov 2024
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    Impaired pheromone detection and abnormal sexual behavior in female mice deficient for ancV1R
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    Building a community-driven bioinformatics platform to facilitate Cannabis sativa multi-omics research
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  35. Sep 2024
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    Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Aberrantly Overexpressed Polo-like Kinase 4 Is a Potential Effective Treatment for DNA Damage Repair–Deficient Uterine Leiomyosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369621/
  38. Aug 2024
  39. www.biorxiv.org www.biorxiv.org
    The multi-level effect of chlorpyrifos during clownfish metamorphosis
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    Impact of rare structural variant events in newly diagnosed multiple myeloma
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  41. Jul 2024
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Pgb1 locus controls glycogen aggregation in astrocytes of the aged hippocampus without impacting cognitive function
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    Loss of ADAM29 does not affect viability and fertility in mice but improves wound healing
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  44. Jun 2024
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    Surgical tumour resection deregulates Hallmarks of Cancer in resected tissue and the surrounding microenvironment
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    Transcriptomic gene signatures measure satellite cell activity in muscular dystrophies
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  47. May 2024
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    CDK7 kinase activity promotes RNA polymerase II promoter escape by facilitating initiation factor release
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  50. Mar 2024
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    Mesenchyme instructs growth while epithelium directs branching in the mouse mammary gland
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    A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture
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    ncbi.nlm.nih.gov/pmc/articles/PMC10945709/
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    Quantitative proteome dynamics across embryogenesis in a model chordate
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    Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment
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    Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans
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    De novo and histologically transformed small cell lung cancer is sensitive to lurbinectedin treatment through the modulation of EMT and NOTCH signaling pathways
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    CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10528807/
  58. Feb 2024
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
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    An iron rheostat controls hematopoietic stem cell fate
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    Single-cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, aging, and disease
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10527051/
  63. www.biorxiv.org www.biorxiv.org
    A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer
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    biorxiv.org/content/10.1101/2023.12.10.570854v1
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    Neural extracellular matrix regulates visual sensory motor integration
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  65. Jan 2024
  66. www.science.org www.science.org
    Temporal landscape of mitochondrial proteostasis governed by the UPRmt
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    science.org/doi/10.1126/sciadv.adh8228
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation
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    An exhausted-like microglial population accumulates in aged and APOE4 genotype Alzheimer’s brains
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  69. Dec 2023
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis
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    Differential benefit of metronomic chemotherapy among triple negative breast cancer subtypes treated in the IBCSG Trial 22-00
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    dx.doi.org/10.1158/1078-0432.CCR-23-1267
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome organization regulates nuclear pore complex formation and promotes differentiation during Drosophila oogenesis
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  74. Nov 2023
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    Genomic and transcriptomic characterization of delta SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus)
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    Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions
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  77. Oct 2023
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    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression
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  80. Sep 2023
  81. www.science.org www.science.org
    Temporal landscape of mitochondrial proteostasis governed by the UPRmt
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    science.org/doi/10.1126/sciadv.adh8228
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features
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    ncbi.nlm.nih.gov/pmc/articles/PMC10502474/
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    Thermophilic methane oxidation is widespread in Aotearoa-New Zealand geothermal fields
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    Peeling back the layers of coral holobiont multi-omics data
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  85. Aug 2023
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spermatogonial fate in mice with increased activin A bioactivity and testicular somatic cell tumours
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    ncbi.nlm.nih.gov/pmc/articles/PMC10409995/
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    Longitudinal map of transcriptome changes in the Lyme pathogen Borrelia burgdorferi during tick-borne transmission
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    ncbi.nlm.nih.gov/pmc/articles/PMC10393048/
  88. Jul 2023
  89. www.sciencedirect.com www.sciencedirect.com
    Nucleocytoplasmic mRNA redistribution accompanies RNA binding protein mislocalization in ALS motor neurons and is restored by VCP ATPase inhibition
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    sciencedirect.com/science/article/pii/S0896627323004786
  90. Jun 2023
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    5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling
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    sciencedirect.com/science/article/pii/S2211124723005715
  92. May 2023
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adipose tissue plasticity in pheochromocytoma patients suggests a role of the splicing machinery in human adipose browning
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    ncbi.nlm.nih.gov/pmc/articles/PMC10209542/
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    Neural extracellular matrix regulates visual sensory motor integration
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    Relationships between gene expression and behavior in mice in response to systemic modulation of the O-GlcNAcylation pathway
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    52.53.155.43/91708249814bb69a32598df046fda7e66eaa9543/Journal of Neurochemistry - 2023 - Bell - Relationships between gene expression and behavior in mice in response to-html.html
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    TF-Prioritizer: a Java pipeline to prioritize condition-specific transcription factors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10155229/
  97. Apr 2023
  98. www.sciencedirect.com www.sciencedirect.com
    Glucocorticoid-mediated induction of ZBTB16 affects insulin secretion in human islets and EndoC-βH1 β-cells
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    sciencedirect.com/science/article/pii/S2589004223006326
  99. www.biorxiv.org www.biorxiv.org
    Single cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, ageing and disease
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    biorxiv.org/content/10.1101/2023.04.20.537553v1
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intronic Cis-Element DR8 in hTERT Is Bound by Splicing Factor SF3B4 and Regulates hTERT Splicing in Non-Small Cell Lung Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9532359/
  101. Mar 2023
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome assembly of the roundjaw bonefish (Albula glossodonta), a vulnerable circumtropical sportfish
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    ncbi.nlm.nih.gov/pmc/articles/PMC10038134/
  103. www.nature.com www.nature.com
    A noncanonical response to replication stress protects genome stability through ROS production, in an adaptive manner
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    nature.com/articles/s41418-023-01141-0
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes
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    ncbi.nlm.nih.gov/pmc/articles/PMC9949800/
  105. Feb 2023
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9903082/
  107. aacrjournals.org aacrjournals.org
    Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling
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    aacrjournals.org/cancerres/article/83/2/219/715076/Plk1-Inhibitors-and-Abiraterone-Synergistically
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of PBRM1 alters promoter histone modifications and activates ALDH1A1 to drive renal cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9357026/
  109. Jan 2023
  110. onlinelibrary.wiley.com onlinelibrary.wiley.com
    In vitro characterization on the role of APOE polymorphism in human hippocampal neurogenesis
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    onlinelibrary.wiley.com/doi/10.1002/hipo.23502
  111. Nov 2022
  112. www.sciencedirect.com www.sciencedirect.com
    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
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    sciencedirect.com/science/article/abs/pii/S1097276522010644
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opposing effects of chronic glucagon receptor agonism and antagonism on amino acids, hepatic gene expression, and alpha cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9618771/
  114. Oct 2022
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cannabinoid signaling modulation through JZL184 restores key phenotypes of a mouse model for Williams–Beuren syndrome
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human PSCs determine the competency of cerebral organoid differentiation via FGF signaling and epigenetic mechanisms
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  117. Sep 2022
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    Loss of key endosymbiont genes may facilitate early host control of the chromatophore in Paulinella
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  119. Aug 2022
  120. 52.53.155.43 52.53.155.43
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells
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  122. Jun 2022
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  124. www.sciencedirect.com www.sciencedirect.com
    MacroH2As regulate enhancer-promoter contacts affecting enhancer activity and sensitivity to inflammatory cytokines
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  125. Apr 2022
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    CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity
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  127. Mar 2022
  128. elifesciences.org elifesciences.org
    Nuclear hormone receptor NHR-49 acts in parallel with HIF-1 to promote hypoxia adaptation in Caenorhabditis elegans
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  129. elifesciences.org elifesciences.org
    Novel insights from a multiomics dissection of the Hayflick limit
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  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A test of the pioneer factor hypothesis using ectopic liver gene activation
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  131. Feb 2022
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    Differential regulation of cranial and cardiac neural crest by serum response factor and its cofactors
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  133. Jan 2022
  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancer RNA Expression in Response to Glucocorticoid Treatment in Murine Macrophages
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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Altered temporal sequence of transcriptional regulators in the generation of human cerebellar granule cells
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Naive and memory CD4+ T cell subsets can contribute to the generation of human Tfh cells
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  138. Dec 2021
  139. elifesciences.org elifesciences.org
    scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution
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  140. Nov 2021
  141. www.sciencedirect.com www.sciencedirect.com
    Multi-tumor analysis of cancer-stroma interactomes of patient-derived xenografts unveils the unique homeostatic process in renal cell carcinomas
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    Homer1a regulates Shank3 expression and underlies behavioral vulnerability to stress in a model of Phelan-McDermid syndrome
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    CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies
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  144. Sep 2021
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    Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins
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    Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation
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  147. Aug 2021
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    Conditional stomatal closure in a fern shares molecular features with flowering plant active stomatal responses
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function
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    The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Global donor and acceptor splicing site kinetics in human cells
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  152. Jul 2021
  153. academic.oup.com academic.oup.com
    Sex Differences in Adrenal Bmal1 Deletion-Induced Augmentation of Glucocorticoid Responses to Stress and ACTH in Mice
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  154. elifesciences.org elifesciences.org
    Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans
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  155. www.sciencedirect.com www.sciencedirect.com
    Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphoma
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  156. Jun 2021
  157. www.frontiersin.org www.frontiersin.org
    Monocytic Ontogeny of Regenerated Macrophages Characterizes the Mesotheliomagenic Responses to Carbon Nanotubes
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  158. May 2021
  159. onlinelibrary.wiley.com onlinelibrary.wiley.com
    As above, so below: Whole transcriptome profiling demonstrates strong molecular similarities between avian dorsal and ventral pallial subdivisions
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  160. www.sciencedirect.com www.sciencedirect.com
    Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer
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  161. www.sciencedirect.com www.sciencedirect.com
    Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues
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  162. Apr 2021
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    Erosion of human X chromosome inactivation causes major remodeling of the iPSC proteome
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  164. www.sciencedirect.com www.sciencedirect.com
    Efficient RNA polymerase II pause release requires U2 snRNP function
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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional profiling reveals potential involvement of microvillous TRPM5-expressing cells in viral infection of the olfactory epithelium
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  166. Mar 2021
  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EKLF/KLF1 expression defines a unique macrophage subset during mouse erythropoiesis
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  168. Feb 2021
  169. www.sciencedirect.com www.sciencedirect.com
    CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes
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  170. www.sciencedirect.com www.sciencedirect.com
    The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers
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  171. Jan 2021
  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism
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  173. Nov 2020
  174. www.sciencedirect.com www.sciencedirect.com
    CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes
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  175. Sep 2020
  176. www.sciencedirect.com www.sciencedirect.com
    Regulatory Dynamics of Tet1 and Oct4 Resolve Stages of Global DNA Demethylation and Transcriptomic Changes in Reprogramming
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  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    De novo Assembly of Transcriptomes From a B73 Maize Line Introgressed With a QTL for Resistance to Gray Leaf Spot Disease Reveals a Candidate Allele of a Lectin Receptor-Like Kinase
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression
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  179. Jan 2020
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis
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  181. www.sciencedirect.com www.sciencedirect.com
    Active and Repressed Chromatin Domains Exhibit Distinct Nucleosome Segregation during DNA Replication
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  182. www.sciencedirect.com www.sciencedirect.com
    IL-10-Dependent Crosstalk between Murine Marginal Zone B Cells, Macrophages, and CD8α+ Dendritic Cells Promotes Listeria monocytogenes Infection
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  183. elifesciences.org elifesciences.org
    Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myofibril diameter is set by a finely tuned mechanism of protein oligomerization in Drosophila
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  185. www.sciencedirect.com www.sciencedirect.com
    A Pan-cancer Transcriptome Analysis Reveals Pervasive Regulation through Alternative Promoters
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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Accumulating computational resource usage of genomic data analysis workflow to optimize cloud computing instance selection
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