81 Matching Annotations
  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Discovery and characterization of a pan-betacoronavirus S2-binding antibody
    1
    1. scibot 27 Sep 2024
      SCR_017293

      DOI: 10.1016/j.str.2024.08.022

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    sciencedirect.com/science/article/pii/S0969212624003691
  3. www.sciencedirect.com www.sciencedirect.com
    Dynamic allostery drives autocrine and paracrine TGF-β signaling
    1
    1. scibot 17 Sep 2024
      RRID:SCR_017293

      DOI: 10.1016/j.cell.2024.08.036

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    sciencedirect.com/science/article/pii/S0092867424009656
  4. Jul 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-electron tomography reveals the microtubule-bound form of inactive LRRK2
    1
    1. scibot 14 Jul 2024
      RRID:SCR_017293

      DOI: 10.1101/2024.06.18.599606

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    ncbi.nlm.nih.gov/pmc/articles/PMC11212993/
  6. Jun 2024
  7. www.sciencedirect.com www.sciencedirect.com
    POT1 recruits and regulates CST-Polα/primase at human telomeres
    1
    1. scibot 05 Jun 2024
      RRID:SCR_017293

      DOI: 10.1016/j.cell.2024.05.002

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    sciencedirect.com/science/article/pii/S0092867424004938
  8. May 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Autophagy preferentially degrades non-fibrillar polyQ aggregates
    1
    1. scibot 17 May 2024
      RRID:SCR_017293

      DOI: 10.1016/j.molcel.2024.04.018

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    sciencedirect.com/science/article/pii/S1097276524003836
  10. Apr 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission
    1
    1. scibot 25 Apr 2024
      RRID:SCR_017293

      DOI: 10.1016/j.devcel.2024.04.008

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    sciencedirect.com/science/article/pii/S1534580724002338
  12. www.nature.com www.nature.com
    Visualizing chaperone-mediated multistep assembly of the human 20S proteasome
    1
    1. scibot 11 Apr 2024
      RRID:SCR_017293

      DOI: 10.1038/s41594-024-01268-9

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    nature.com/articles/s41594-024-01268-9
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of ligand specificity and channel activation in an insect gustatory receptor
    1
    1. scibot 04 Apr 2024
      RRID:SCR_017293

      DOI: 10.1016/j.celrep.2024.114035

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    ncbi.nlm.nih.gov/pmc/articles/PMC11100771/
  14. Mar 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural mechanisms for VMAT2 inhibition by tetrabenazine
    1
    1. scibot 27 Mar 2024
      RRID:SCR_017293

      DOI: 10.7554/eLife.91973

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959523/
  16. www.sciencedirect.com www.sciencedirect.com
    ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat
    2
    1. scibot 15 Mar 2024
      RRID:SCR_017293

      DOI: 10.1016/j.cell.2024.02.013

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    2. scibot 15 Mar 2024
      RRID:SCR_017293

      DOI: 10.1016/j.cell.2024.02.013

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    sciencedirect.com/science/article/pii/S009286742400179X
  17. Feb 2024
  18. www.sciencedirect.com www.sciencedirect.com
    A metabolically controlled contact site between vacuoles and lipid droplets in yeast
    3
    1. scibot 21 Feb 2024
      RRID:SCR_017293

      DOI: 10.1016/j.devcel.2024.01.016

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    2. scibot 21 Feb 2024
      RRID:SCR_017293

      DOI: 10.1016/j.devcel.2024.01.016

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    3. scibot 21 Feb 2024
      RRID:SCR_017293

      DOI: 10.1016/j.devcel.2024.01.016

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    sciencedirect.com/science/article/pii/S1534580724000364
  19. Nov 2023
  20. www.sciencedirect.com www.sciencedirect.com
    The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus
    1
    1. scibot 17 Nov 2023
      RRID:SCR_017293

      DOI: 10.1016/j.celrep.2023.113366

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    sciencedirect.com/science/article/pii/S2211124723013785
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Membrane remodeling properties of the Parkinson’s disease protein LRRK2
    1
    1. scibot 02 Nov 2023
      RRID:SCR_017293

      DOI: 10.1073/pnas.2309698120

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    ncbi.nlm.nih.gov/pmc/articles/PMC10614619/
  22. Oct 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly
    1
    1. scibot 28 Oct 2023
      RRID:SCR_017293

      DOI: 10.1016/j.molcel.2023.09.037

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    sciencedirect.com/science/article/pii/S1097276523008031
  24. Aug 2023
  25. 52.53.155.43 52.53.155.43
    Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels
    2
    1. scibot 12 Aug 2023
      RRID:SCR_017293

      DOI: 10.1016/j.celrep.2023.112926

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    2. scibot 10 Aug 2023
      SCR_017293

      DOI: 10.1016/j.celrep.2023.112926

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    52.53.155.43/13d2314e1a08e5e99d70c8b4a30c497d5ddefb63/PIIS2211124723009373-html.html
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heterogeneous non-canonical nucleosomes predominate in yeast cells in situ
    1
    1. scibot 01 Aug 2023
      RRID:SCR_017293

      DOI: 10.7554/eLife.87672

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    ncbi.nlm.nih.gov/pmc/articles/PMC10382156/
  27. Jul 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor
    1
    1. scibot 14 Jul 2023
      RRID:SCR_017293

      DOI: 10.7554/eLife.86029

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    ncbi.nlm.nih.gov/pmc/articles/PMC10338036/
  29. Jun 2023
  30. www.sciencedirect.com www.sciencedirect.com
    A structural blueprint for interleukin-21 signal modulation
    1
    1. scibot 21 Jun 2023
      RRID:SCR_017293

      DOI: 10.1016/j.celrep.2023.112657

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    sciencedirect.com/science/article/pii/S221112472300668X
  31. Apr 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Systematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypes
    1
    1. scibot 08 Apr 2023
      RRID:SCR_017293

      DOI: 10.1016/j.celrep.2023.112370

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    sciencedirect.com/science/article/pii/S2211124723003819
  33. Feb 2023
  34. www.nature.com www.nature.com
    The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
    1
    1. scibot 04 Feb 2023
      RRID:SCR_017293

      DOI: 10.1038/s41467-023-36058-2

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    nature.com/articles/s41467-023-36058-2
  35. Jan 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Nucleosome dyad determines the H1 C-terminus collapse on distinct DNA arms
    1
    1. scibot 07 Jan 2023
      RRID:SCR_017293

      DOI: 10.1016/j.str.2022.12.005

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    sciencedirect.com/science/article/pii/S0969212622004919
  37. www.sciencedirect.com www.sciencedirect.com
    The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions
    1
    1. scibot 02 Jan 2023
      RRID:SCR_017293

      DOI: 10.1016/j.celrep.2022.111902

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    sciencedirect.com/science/article/pii/S2211124722018010
  38. Dec 2022
  39. jitc.bmj.com jitc.bmj.com
    Anti-CD73 antibody activates human B cells, enhances humoral responses and induces redistribution of B cells in patients with cancer
    1
    1. scibot 08 Dec 2022
      RRID:SCR_017293

      DOI: 10.1136/jitc-2022-005802

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    jitc.bmj.com/content/10/12/e005802
  40. Nov 2022
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes
    1
    1. scibot 16 Nov 2022
      RRID:SCR_017293

      DOI: 10.1016/j.immuni.2022.10.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC9606073/
  42. Oct 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Condensation of the fusion focus by the intrinsically disordered region of the formin Fus1 is essential for cell-cell fusion
    1
    1. scibot 06 Oct 2022
      RRID:SCR_017293

      DOI: 10.1016/j.cub.2022.09.026

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    sciencedirect.com/science/article/pii/S0960982222014701
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ structural analysis reveals membrane shape transitions during autophagosome formation
    1
    1. scibot 01 Oct 2022
      RRID:SCR_017293

      DOI: 10.1073/pnas.2209823119

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    ncbi.nlm.nih.gov/pmc/articles/PMC9522377/
  45. www.sciencedirect.com www.sciencedirect.com
    A step-by-step protocol for capturing conformational snapshots of ligand gated ion channels by single-particle cryo-EM
    1
    1. scibot 01 Oct 2022
      RRID:SCR_017293

      DOI: 10.1016/j.xpro.2022.101732

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    sciencedirect.com/science/article/pii/S2666166722006128
  46. Sep 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Ultrastructural analysis of wild-type and RIM1α knockout active zones in a large cortical synapse
    1
    1. scibot 21 Sep 2022
      RRID:SCR_017293

      DOI: 10.1016/j.celrep.2022.111382

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    sciencedirect.com/science/article/pii/S2211124722012177
  48. Jun 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex
    1
    1. scibot 10 Jun 2022
      RRID:SCR_017293

      DOI: 10.1016/j.cell.2022.04.016

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    sciencedirect.com/science/article/pii/S0092867422004639
  50. Apr 2022
  51. www.sciencedirect.com www.sciencedirect.com
    RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex
    1
    1. scibot 27 Apr 2022
      RRID:SCR_017293

      DOI: 10.1016/j.celrep.2022.110732

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    sciencedirect.com/science/article/pii/S2211124722004934
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis Of Memory B Cells Identifies Conserved Neutralizing Epitopes On The N-Terminal Domain Of Variant SARS-Cov-2 Spike Proteins
    1
    1. scibot 22 Apr 2022
      RRID:SCR_017293

      DOI: 10.1016/j.immuni.2022.04.003

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    ncbi.nlm.nih.gov/pmc/articles/PMC8986478/
  53. Mar 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB
    1
    1. scibot 06 Mar 2022
      RRID:SCR_017293

      DOI: 10.1016/j.str.2022.02.007

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    sciencedirect.com/science/article/pii/S0969212622000430
  55. Jan 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia elucidated by cryo-electron tomography
    1
    1. scibot 26 Jan 2022
      RRID:SCR_017293

      DOI: 10.7554/eLife.74512

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    ncbi.nlm.nih.gov/pmc/articles/PMC8776254/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern
    1
    1. scibot 05 Jan 2022
      SCR_017

      DOI: 10.1016/j.celrep.2021.110210

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    ncbi.nlm.nih.gov/pmc/articles/PMC8673750/
  58. Oct 2021
  59. rupress.org rupress.org
    Cnm1 mediates nucleus–mitochondria contact site formation in response to phospholipid levels
    1
    1. scibot 29 Oct 2021
      RRID:SCR_017293

      DOI: 10.1083/jcb.202104100

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    rupress.org/jcb/article/220/11/e202104100/212719/Cnm1-mediates-nucleus-mitochondria-contact-site
  60. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ultrastructure of ipsilateral and contralateral tectopulvinar projections in the mouse
    1
    1. scibot 29 Oct 2021
      RRID:SCR_017293

      DOI: 10.1002/cne.25264

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    onlinelibrary.wiley.com/doi/10.1002/cne.25264
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells
    1
    1. scibot 02 Oct 2021
      RRID:SCR_017293

      DOI: 10.7554/eLife.71474

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    ncbi.nlm.nih.gov/pmc/articles/PMC8480983/
  62. Sep 2021
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies
    1
    1. scibot 18 Sep 2021
      RRID:SCR_017293

      DOI: 10.1016/j.celrep.2021.109760

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    ncbi.nlm.nih.gov/pmc/articles/PMC8423902/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of human mTOR complexes by DEPTOR
    1
    1. scibot 18 Sep 2021
      RRID:SCR_017293

      DOI: 10.7554/eLife.70871

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  65. www.sciencedirect.com www.sciencedirect.com
    Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
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  66. www.sciencedirect.com www.sciencedirect.com
    Cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein
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    sciencedirect.com/science/article/pii/S2211124721010664
  67. Aug 2021
  68. www.sciencedirect.com www.sciencedirect.com
    The 3D architecture and molecular foundations of de novo centriole assembly via bicentrioles
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  69. www.sciencedirect.com www.sciencedirect.com
    Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural heterogeneity of cellular K5/K14 filaments as revealed by cryo-electron microscopy
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission
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  73. Jul 2021
  74. elifesciences.org elifesciences.org
    A contractile injection system stimulates tubeworm metamorphosis by translocating a proteinaceous effector
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  75. elifesciences.org elifesciences.org
    The molecular architecture of engulfment during Bacillus subtilis sporulation
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  76. elifesciences.org elifesciences.org
    Self-capping of nucleoprotein filaments protects Newcastle Disease Virus genome
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  77. Jun 2021
  78. www.sciencedirect.com www.sciencedirect.com
    B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV
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  79. May 2021
  80. www.cell.com www.cell.com
    The structure and spontaneous curvature of clathrin lattices at the plasma membrane
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    cell.com/developmental-cell/fulltext/S1534-5807(21)00243-4
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ architecture of neuronal α-Synuclein inclusions
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  82. Apr 2021
  83. www.sciencedirect.com www.sciencedirect.com
    Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex
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    sciencedirect.com/science/article/pii/S0969212621001192
  84. Mar 2021
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A pentameric protein ring with novel architecture is required for herpesviral packaging
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  87. www.sciencedirect.com www.sciencedirect.com
    Structural basis for self-cleavage prevention by tag:anti-tag pairing complementarity in type VI Cas13 CRISPR systems
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    sciencedirect.com/science/article/pii/S1097276520309540
  88. Feb 2021
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures reveal gatekeeping of the mitochondrial Ca2+ uniporter by MICU1-MICU2
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  90. elifesciences.org elifesciences.org
    Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy
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  91. www.sciencedirect.com www.sciencedirect.com
    Cone-shaped HIV-1 capsids are transported through intact nuclear pores
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  92. Jan 2021
  93. elifesciences.org elifesciences.org
    Atomic structures of respiratory complex III 2, complex IV, and supercomplex III 2-IV from vascular plants
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients
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    ncbi.nlm.nih.gov/pmc/articles/PMC7785296/
  95. Dec 2020
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7723414/
  97. www.sciencedirect.com www.sciencedirect.com
    Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition
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      DOI: 10.1016/j.chom.2020.11.007

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    sciencedirect.com/science/article/pii/S1931312820306247
  98. Oct 2020
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch
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  100. Sep 2020
  101. www.sciencedirect.com www.sciencedirect.com
    Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices
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      DOI: 10.1016/j.neuron.2020.09.004

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    sciencedirect.com/science/article/pii/S0896627320307042
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemical and structural investigation of the paroxetine-human serotonin transporter complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC7470834/
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structures of S-OPA1 reveal its interactions with membrane and changes upon nucleotide binding
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    ncbi.nlm.nih.gov/pmc/articles/PMC7156267/
  104. www.sciencedirect.com www.sciencedirect.com
    Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage
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  105. elifesciences.org elifesciences.org
    Structure and activation mechanism of the BBSome membrane protein trafficking complex
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      DOI: 10.7554/eLife.53322

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    elifesciences.org/articles/53322
  106. elifesciences.org elifesciences.org
    Cryo-EM structure of the lysosomal chloride-proton exchanger CLC-7 in complex with OSTM1
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      RRID:SCR_017293

      DOI: 10.7554/eLife.59555

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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atomic structure of a mitochondrial complex I intermediate from vascular plants
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      DOI: 10.7554/eLife.56664

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    ncbi.nlm.nih.gov/pmc/articles/PMC7447434/
  108. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM Reveals Integrin-Mediated TGF-β Activation without Release from Latent TGF-β
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      DOI: 10.1016/j.cell.2019.12.030

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    sciencedirect.com/science/article/pii/S0092867419313923
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies
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      DOI: 10.1016/j.cell.2020.06.025

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    ncbi.nlm.nih.gov/pmc/articles/PMC7311918/
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures reveal gatekeeping of the mitochondrial Ca2+ uniporter by MICU1-MICU2
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      RRID:SCR_017293

      DOI: 10.7554/eLife.59991

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    ncbi.nlm.nih.gov/pmc/articles/PMC7434445/
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gating and selectivity mechanisms for the lysosomal K+ channel TMEM175
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      DOI: 10.7554/eLife.53430

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    ncbi.nlm.nih.gov/pmc/articles/PMC7141809/
  112. Jan 2020
  113. www.sciencedirect.com www.sciencedirect.com
    Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity
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      DOI: 10.1016/j.devcel.2019.10.018

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    sciencedirect.com/science/article/pii/S1534580719308652
  114. www.sciencedirect.com www.sciencedirect.com
    Multisystem Proteinopathy Mutations in VCP/p97 Increase NPLOC4·UFD1L Binding and Substrate Processing
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      DOI: 10.1016/j.str.2019.09.011

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