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    The immune landscape of murine skeletal muscle regeneration and aging
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    1. scibot 20 Nov 2024
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    sciencedirect.com/science/article/pii/S2211124724013263
  3. Nov 2024
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    Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair
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    1. scibot 16 Nov 2024
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    sciencedirect.com/science/article/pii/S0092867424011589
  5. 52.53.155.43 52.53.155.43
    can-24-2248-html.html
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    1. scibot 08 Nov 2024
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  6. Oct 2024
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    A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier
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    1. scibot 02 Oct 2024
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      DOI: 10.1158/0008-5472.CAN-19-3911

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    aacrjournals.org/cancerres/article/81/3/619/648134/A-High-Content-Screen-Identifies-Drugs-That
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    Transcriptomic cell-type specificity of local cortical circuits
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    1. scibot 02 Oct 2024
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    sciencedirect.com/science/article/pii/S0896627324006512
  9. Sep 2024
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    Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
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    sciencedirect.com/science/article/pii/S0012160624002343
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    A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies
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    1. scibot 27 Sep 2024
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    sciencedirect.com/science/article/pii/S2666379124004774
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    Discovery and characterization of a pan-betacoronavirus S2-binding antibody
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    1. scibot 27 Sep 2024
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    sciencedirect.com/science/article/pii/S0969212624003691
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    CXCR4 orchestrates the TOX-programmed exhausted phenotype of CD8+ T cells via JAK2/STAT3 pathway
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    1. scibot 26 Sep 2024
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    sciencedirect.com/science/article/pii/S2666979X24002702
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    Single-Cell Profiling Shows Murine Forebrain Neural Stem Cells Reacquire a Developmental State when Activated for Adult Neurogenesis
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    1. scibot 25 Sep 2024
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    Protocol for Dissection and Dissociation of Zebrafish Telencephalon for Single-Cell Sequencing
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    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.xpro.2020.100042

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    ABCA7-dependent induction of neuropeptide Y is required for synaptic resilience in Alzheimer’s disease through BDNF/NGFR signaling
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    1. scibot 04 Sep 2024
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    Regulatory mechanisms orchestrating cellular diversity of Cd36+ olfactory sensory neurons revealed by scRNA-seq and scATAC-seq analysis
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    1. scibot 04 Sep 2024
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    sciencedirect.com/science/article/pii/S2211124724010222
  18. Aug 2024
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    Genetic association with autoimmune diseases identifies molecular mechanisms of coronary artery disease
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    1. scibot 28 Aug 2024
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    Single-cell dissection of the human blood-brain barrier and glioma blood-tumor barrier
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    1. scibot 27 Aug 2024
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    cell.com/neuron/fulltext/S0896-6273(24)00571-3
  21. www.biorxiv.org www.biorxiv.org
    Experimental and Computational Methods for Allelic Imbalance Analysis from Single-Nucleus RNA-seq Data
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    Time- and cell-specific activation of BMP signaling restrains chondrocyte hypertrophy
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    sciencedirect.com/science/article/pii/S2589004224017620
  23. Jul 2024
  24. www.cell.com www.cell.com
    Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
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    cell.com/immunity/fulltext/S1074-7613(24)00348-0
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    The primitive endoderm supports lineage plasticity to enable regulative development
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    1. scibot 24 Jul 2024
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    The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1
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    1. scibot 23 Jul 2024
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      DOI: 10.1126/sciadv.adk1296

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    Single-cell spatial multiomics reveals tumor microenvironment vulnerabilities in cancer resistance to immunotherapy
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    cell.com/cell-reports/fulltext/S2211-1247(24)00720-4
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    Single-cell RNA Sequencing Identifies a Novel Subtype of Microglia with High Cd74 Expression that Facilitates White Matter Inflammation During Chronic Cerebral Hypoperfusion
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    1. scibot 23 Jul 2024
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      DOI: 10.1007/s11064-024-04206-9

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    Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer
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    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.medj.2024.06.002

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    sciencedirect.com/science/article/pii/S2666634024002484
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    Semaphorin 6D tunes amygdalar circuits for emotional, metabolic, and inflammatory outputs
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    1. scibot 17 Jul 2024
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      DOI: 10.1016/j.neuron.2024.06.017

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  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptic plasticity in human thalamocortical assembloids
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    ncbi.nlm.nih.gov/pmc/articles/PMC11407288/
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    Mitochondrial perturbation in the intestine causes microbiota-dependent injury and gene signatures discriminative of inflammatory disease
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      DOI: 10.1016/j.chom.2024.06.013

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    sciencedirect.com/science/article/pii/S1931312824002312
  33. www.biorxiv.org www.biorxiv.org
    A rewiring of the earliest immune events leading to T-cell mediated disease following intestinal microbial infection in a PINK1KO mouse model of Parkinson’s disease
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    1. scibot 04 Jul 2024
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      DOI: 10.1101/2024.06.18.598931

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    biorxiv.org/content/10.1101/2024.06.18.598931v1
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1
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    1. scibot 02 Jul 2024
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      DOI: 10.1126/sciadv.adk1296

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  35. Jun 2024
  36. www.sciencedirect.com www.sciencedirect.com
    Intergenic risk variant rs56258221 skews the fate of naive CD4+ T cells via miR4464-BACH2 interplay in primary sclerosing cholangitis
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    The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies
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    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.immuni.2024.05.017

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    sciencedirect.com/science/article/pii/S1074761324002711
  38. May 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrating single‐cell and spatial analysis reveals MUC1‐mediated cellular crosstalk in mucinous colorectal adenocarcinoma
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      DOI: 10.1002/ctm2.1701

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    ncbi.nlm.nih.gov/pmc/articles/PMC11111627/
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    Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming
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    1. scibot 24 May 2024
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      DOI: 10.7554/eLife.87756

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    ncbi.nlm.nih.gov/pmc/articles/PMC11111218/
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    Phenotypic and spatial heterogeneity of brain myeloid cells after stroke is associated with cell ontogeny, tissue damage, and brain connectivity
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    sciencedirect.com/science/article/pii/S2211124724005783
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    Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma
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      DOI: 10.1016/j.ccell.2024.04.012

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    sciencedirect.com/science/article/pii/S1535610824001363
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    Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation
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      DOI: 10.1016/j.stem.2024.04.015

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    sciencedirect.com/science/article/pii/S1934590924001425
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    Antigen-level resolution of commensal-specific B cell responses can be enabled by phage display screening coupled with B cell tetramers
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      DOI: 10.1016/j.immuni.2024.04.014

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    sciencedirect.com/science/article/pii/S107476132400219X
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    Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy
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      DOI: 10.1016/j.cell.2024.04.015

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    sciencedirect.com/science/article/pii/S0092867424004100
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    Genome sequence analyses identify novel risk loci for multiple system atrophy
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      DOI: 10.1016/j.neuron.2024.04.002

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      DOI: 10.1016/j.neuron.2024.04.002

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    sciencedirect.com/science/article/pii/S089662732400240X
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thrombopoietin mimetic stimulates bone marrow vascular and stromal niches to mitigate acute radiation syndrome
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      DOI: 10.1186/s13287-024-03734-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC11057170/
  48. Apr 2024
  49. www.sciencedirect.com www.sciencedirect.com
    Changes in the cellular makeup of motor patterning circuits drive courtship song evolution in Drosophila
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      DOI: 10.1016/j.cub.2024.04.020

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    sciencedirect.com/science/article/pii/S0960982224004603
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    Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses
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    Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti–PD-1 Therapy
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    Single-nucleus RNA sequencing demonstrates an autosomal dominant Alzheimer’s disease profile and possible mechanisms of disease protection
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    Protocol for the detection of defined T cell clones in a heterogeneous cell population
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    Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia
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    Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer
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  93. Nov 2023
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    Truncated radial glia as a common precursor in the late corticogenesis of gyrencephalic mammals
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    Structured wound angiogenesis instructs mesenchymal barrier compartments in the regenerating nerve
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    LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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    Single-cell and spatial analyses reveal a tradeoff between murine mammary proliferation and lineage programs associated with endocrine cues
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    Single-cell transcriptomics illuminates regulatory steps driving anterior-posterior patterning of Drosophila embryonic mesoderm
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    BRI2-mediated regulation of TREM2 processing in microglia and its potential implications for Alzheimer’s disease and related dementias
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  109. Sep 2023
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    Single-cell multi-omics defines the cell-type-specific impact of splicing aberrations in human hematopoietic clonal outgrowths
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    Enrichment of carcinogen-driven “mitochondria-primed” human skin stem cells and their identification using single-cell analyses
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    Molecularly targetable cell types in mouse visual cortex have distinguishable prediction error responses
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    Activin A-mediated polarization of cancer-associated fibroblasts and macrophages confers resistance to checkpoint immunotherapy in skin cancer
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    Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity
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    Interaction of an α-synuclein epitope with HLA-DRB1∗15:01 triggers enteric features in mice reminiscent of prodromal Parkinson’s disease
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    Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression
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    Homeostatic PD-1 signaling restrains EOMES-dependent oligoclonal expansion of liver-resident CD8 T cells
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    Early clonal extinction in glioblastoma progression revealed by genetic barcoding
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    Sex shapes cell-type-specific transcriptional signatures of stress exposure in the mouse hypothalamus
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    sox1a:eGFP transgenic line and single-cell transcriptomics reveal the origin of zebrafish intraspinal serotonergic neurons
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    GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of Colorectal Cancer
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    Low-level repressive histone marks fine-tune gene transcription in neural stem cells
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    A single-cell atlas of the sexually dimorphic Drosophila foreleg and its sensory organs during development
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  135. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Obesity during preclinical Alzheimer's disease development exacerbates brain metabolic decline
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  136. Jun 2023
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    Claustral neurons projecting to frontal cortex restrict opioid consumption
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    Transcriptomic landscape of early hair follicle and epidermal development
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    Single-cell RNA-seq uncovers novel metabolic functions of Schwann cells beyond myelination
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    The maturation and aging trajectory of Marchantia polymorpha at single-cell resolution
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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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    MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis
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    Asynchronous transcription and translation of neurotransmitter-related genes characterize the initial stages of neuronal maturation in Drosophila
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    Efficient self-organization of blastoids solely from mouse ESCs is facilitated by transient reactivation of 2C gene network
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    Immune mechanisms shape the clonal landscape during early progression of prostate cancer
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    Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia
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  154. www.biorxiv.org www.biorxiv.org
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  155. Apr 2023
  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
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  157. Mar 2023
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    GSK-3 inhibitor elraglusib enhances tumor-infiltrating immune cell activation in tumor biopsies and synergizes with anti-PD-L1 in a murine model of colorectal cancer
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    Endothelial and Leptin Receptor+ cells promote the maintenance of stem cells and hematopoiesis in early postnatal murine bone marrow
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    Single-cell transcriptomic profiling redefines the origin and specification of early adrenogonadal progenitors
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  161. Feb 2023
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    IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii
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    Human hematopoietic stem cell vulnerability to ferroptosis
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    Single-cell transcriptome profiles of Drosophila fruitless-expressing neurons from both sexes
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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver
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    Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells
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  167. Jan 2023
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    Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance
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    Mapping transcriptional heterogeneity and metabolic networks in fatty livers at single-cell resolution
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    Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy
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    Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits
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  172. Dec 2022
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    Clonal transcriptomics identifies mechanisms of chemoresistance and empowers rational design of combination therapies
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    TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development
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    Single-cell RNA sequencing uncovers dynamic roadmap and cell-cell communication during buffalo spermatogenesis
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    Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness Versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis
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    Single-cell RNA sequencing reveals distinct T cell populations in immune-related adverse events of checkpoint inhibitors
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    Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity
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    B cell expansion hinders the stroma-epithelium regenerative cross talk during mucosal healing
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  180. Nov 2022
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    Protein aggregation and calcium dysregulation are hallmarks of familial Parkinson’s disease in midbrain dopaminergic neurons
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    Systematic single-cell pathway analysis to characterize early T cell activation
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    Molecular and anatomical characterization of parabrachial neurons and their axonal projections
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    Derivation of nociceptive sensory neurons from hiPSCs with early patterning and temporally controlled NEUROG2 overexpression
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    CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation
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    Single-cell RNA sequencing reveals different signatures of mesenchymal stromal cell pluripotent-like and multipotent populations
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    Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia
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  188. Oct 2022
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    Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ
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    Interleukin-33-activated neuropeptide CGRP-producing memory Th2 cells cooperate with somatosensory neurons to induce conjunctival itch
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    Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation
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  192. Sep 2022
  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-Cell RNA Sequencing Reveals Molecular Features of Heterogeneity in the Murine Retinal Pigment Epithelium
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      DOI: 10.3390/ijms231810419

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  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of cellular senescence in aging skeletal muscle
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    Landscape and age dynamics of immune cells in the Egyptian rousette bat
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    STAG2 promotes the myelination transcriptional program in oligodendrocytes
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      DOI: 10.7554/eLife.77848

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    Sublethal cytochrome c release generates drug-tolerant persister cells
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  198. Aug 2022
  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunodeficiency syndromes differentially impact the functional spectrum of SARS-CoV-2-specific T cells elicited by mRNA vaccination
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  200. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CXCR4high megakaryocytes regulate host-defense immunity against bacterial pathogens
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    Gliotransmission of D-serine promotes thirst-directed behaviors in Drosophila
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    sciencedirect.com/science/article/pii/S0960982222011757
  202. Jul 2022
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    Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer’s disease
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    Multiomics reveal the central role of pentose phosphate pathway in resident thymic macrophages to cope with efferocytosis-associated stress
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    Bacteria reduce flagellin synthesis to evade microglia-astrocyte-driven immunity in the brain
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  206. Jun 2022
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    Longitudinal single-cell dynamics of chromatin accessibility and mitochondrial mutations in chronic lymphocytic leukemia mirror disease history
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      DOI: 10.1158/2159-8290.CD-21-0276

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  208. May 2022
  209. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    A human breast atlas integrating single-cell proteomics and transcriptomics
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  210. elifesciences.org elifesciences.org
    Integrative analysis of scRNA-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator
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      DOI: 10.7554/eLife.73998

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    An integrated transcriptomic and epigenomic atlas of mouse primary motor cortex cell types
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      DOI: 10.1101/2020.02.29.970558

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    biorxiv.org/content/10.1101/2020.02.29.970558v2
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    Intracellular infection and immune system cues rewire adipocytes to acquire immune function
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      DOI: 10.1016/j.cmet.2022.04.008

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    sciencedirect.com/science/article/pii/S1550413122001358
  213. Apr 2022
  214. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis
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      DOI: 10.7554/eLife.74595

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    Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease
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      DOI: 10.1016/j.stem.2022.03.003

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    sciencedirect.com/science/article/pii/S1934590922001011
  216. www.sciencedirect.com www.sciencedirect.com
    Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease
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      DOI: 10.1016/j.neuron.2022.03.008

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    Cancer cells retrace a stepwise differentiation program during malignant progression
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      DOI: 10.1158/2159-8290.CD-20-1637

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    ncbi.nlm.nih.gov/pmc/articles/PMC7611766/
  218. Mar 2022
  219. www.sciencedirect.com www.sciencedirect.com
    Human and mouse trigeminal ganglia cell atlas implicates multiple cell types in migraine
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    Novel insights from a multiomics dissection of the Hayflick limit
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      DOI: 10.7554/eLife.70283

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  221. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Erythropoietin directly remodels the clonal composition of murine hematopoietic multipotent progenitor cells
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      DOI: 10.7554/eLife.66922

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    ncbi.nlm.nih.gov/pmc/articles/PMC8884727/
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    Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain
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      DOI: 10.7554/eLife.71864

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    Cholesterol biosynthesis defines oligodendrocyte precursor heterogeneity between brain and spinal cord
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      DOI: 10.1016/j.celrep.2022.110423

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    sciencedirect.com/science/article/pii/S2211124722001474
  224. Feb 2022
  225. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target
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      DOI: 10.1038/s41467-022-28372-y

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    The transcriptional corepressor CTBP-1 acts with the SOX family transcription factor EGL-13 to maintain AIA interneuron cell identity in Caenorhabditis elegans
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    ncbi.nlm.nih.gov/pmc/articles/PMC8816384/
  227. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stress conditions promote Leishmania hybridization in vitro marked by expression of the ancestral gamete fusogen HAP2 as revealed by single-cell RNA-seq
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      DOI: 10.7554/eLife.73488

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  228. Jan 2022
  229. www.sciencedirect.com www.sciencedirect.com
    scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells
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      DOI: 10.1016/j.molcel.2021.12.038

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    sciencedirect.com/science/article/pii/S1097276521011436
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    iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling
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      DOI: 10.7554/eLife.70341

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