128 Matching Annotations
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    Integrating large-scale in vitro functional genomic screen and multi-omics data to identify novel breast cancer targets
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    link.springer.com/article/10.1007/s10549-025-07817-0
  3. Aug 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Blocking NRF2 Translation by Inhibition of Cap-Dependent Initiation Sensitizes Lymphoma Cells to Ferroptosis and CAR T-cell Immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12363560/
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    ZYS-1 is not an ADAR1 inhibitor
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    biorxiv.org/content/10.1101/2025.08.08.669362v2
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TBK1 Targeting is Identified as a Therapeutic Strategy to Enhance CAR T-Cell Efficacy Using Patient-Derived Organotypic Tumor Spheroids
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    pmc.ncbi.nlm.nih.gov/articles/PMC11790382/
  7. Jul 2025
  8. www.science.org www.science.org
    Impaired mitochondrial metabolism is a critical cancer vulnerability for MYC inhibitors
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    science.org/doi/10.1126/sciadv.adw5228
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    MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD
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    PHGDH Induction by MAPK is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability
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    pmc.ncbi.nlm.nih.gov/articles/PMC11735329/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for Stearoyl-CoA desaturase (SCD1) (UniProt ID: O00767) for use in western blot, immunoprecipitation, and immunofluorescence
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    The Vps13-like protein BLTP2 regulates phosphatidylethanolamine levels to maintain plasma membrane fluidity and breast cancer aggressiveness
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    nature.com/articles/s41556-025-01672-3
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12202856/
  14. Jun 2025
  15. www.sciencedirect.com www.sciencedirect.com
    Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity
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    sciencedirect.com/science/article/pii/S2211124725006928
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for STING1 (Uniprot ID: Q86WV6) for use in western blot, immunoprecipitation, and immunofluorescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12175898/
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  18. May 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic Plasticity Drives Carcinogenesis and Multi-Therapy Resistance in Multiple Myeloma
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  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for S1PR1 (UniProt ID: P21453) for use in western blot, immunoprecipitation, and immunofluorescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12022542/
  21. Apr 2025
  22. www.sciencedirect.com www.sciencedirect.com
    Histamine 1 Receptor (HRH1): A potential therapeutic target for Pancreatic Ductal Adenocarcinoma
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    sciencedirect.com/science/article/pii/S0022356525397867
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for TAF15 (UniProt ID: Q92804) for use in western blot, immunoprecipitation, and immunofluorescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC11966097/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Profiling the Activity of the Potent and Highly Selective CDK2 Inhibitor BLU-222 Reveals Determinants of Response in CCNE1-Aberrant Ovarian and Endometrial Tumors
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  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KT-253, a Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy than MDM2 Small-Molecule Inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962396/
  26. Mar 2025
  27. www.biorxiv.org www.biorxiv.org
    The carnosinase dipeptidase CNDP1 is a novel metabolic vulnerability in brain metastasis
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    biorxiv.org/content/10.1101/2025.03.18.644053v1
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for Rab1A and Rab1B for use in Western Blot, immunoprecipitation and immunofluorescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC10979127/
  29. Feb 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Potent, Selective, Small-Molecule Inhibitor of DHX9 Abrogates Proliferation of Microsatellite Instable Cancers with Deficient Mismatch Repair
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    pmc.ncbi.nlm.nih.gov/articles/PMC11831107/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D) for use in Western Blot, immunoprecipitation and immunofluorescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC11811605/
  32. Jan 2025
  33. journals.sagepub.com journals.sagepub.com
    Exploring the Correlation Between Hypoxia, HIF1A Variants, and Breast Cancer in Different Ethnicities, and Bangladeshi Women: Through ELISA and Integrative Multi-Omics Analysis
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    journals.sagepub.com/doi/10.1177/11772719241278176
  34. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Efficacy of CBP/p300 Dual Inhibitors against De-repression of KREMEN2 in cBAF-Deficient Cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11701801/
  36. f1000research.com f1000research.com
    A guide to selecting high-performing antibodies for Stearoyl-CoA desaturase (SCD1) (UniProt ID: O00767) for use in western blot, immunoprecipitation, and immunofluorescence
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    f1000research.com/articles/14-10
  37. f1000research.com f1000research.com
    A guide to selecting high-performing antibodies for ADNP (UniProt ID: Q9H2P0) for use in western blot, immunoprecipitation, and immunofluorescence
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    f1000research.com/articles/13-1545
  38. Dec 2024
  39. f1000research.com f1000research.com
    A guide to selecting high-performing antibodies for VAPB (UniProt ID: O95292) for use in western blot, immunoprecipitation, and immunofluorescence
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    f1000research.com/articles/13-1559
  40. f1000research.com f1000research.com
    A guide to selecting high-performing antibodies for STXBP1 (UniProt ID: P61764) for use in western blot, immunoprecipitation, and immunofluorescence
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    f1000research.com/articles/13-1557
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines
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    pmc.ncbi.nlm.nih.gov/articles/PMC11621922/
  42. f1000research.com f1000research.com
    A guide to selecting high-performing antibodies for STING1 (Uniprot ID: Q86WV6) for use in western blot, immunoprecipitation, and immunofluorescence
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    f1000research.com/articles/13-1049
  43. Nov 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for CSNK2A1 (UniProt ID: P68400) for use in western blot, immunoprecipitation and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC11472280/
  45. Oct 2024
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for amyloid-beta precursor protein for use in Western Blot, immunoprecipitation and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC11445640/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacologic inhibition of eIF4A blocks NRF2 synthesis to prevent osteosarcoma metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443218/
  48. Sep 2024
  49. f1000research.com f1000research.com
    A guide to selecting high-performing antibodies for Rab10 (UniProt ID: P61026) for use in western blot, immunoprecipitation, and immunofluorescence
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    f1000research.com/articles/13-1061
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for Secreted frizzled-related protein 1 (sFRP-1) for use in Western Blot and immunoprecipitation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11420615/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MED12 and CDK8/19 modulate androgen receptor activity and enzalutamide response in prostate cancer
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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for Huntingtin (UniProt ID: P42858) for use in western blot, immunoprecipitation, and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC11384196/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for Protein-glutamine gamma-glutamyltransferase 2 (TGM2) for use in western blot, immunoprecipitation and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC11362715/
  54. www.sciencedirect.com www.sciencedirect.com
    GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant
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    sciencedirect.com/science/article/pii/S1535610824003052
  55. Aug 2024
  56. www.sciencedirect.com www.sciencedirect.com
    MiRNA-3163 limits ovarian cancer stem-like cells via targeting SOX-2 transcription factor
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    sciencedirect.com/science/article/pii/S2468054024001173
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for human Midkine for use in Western blot and immunoprecipitation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292187/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p300 KAT Regulates SOX10 Stability and Function in Human Melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11293458/
  59. Jul 2024
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-Myristoyltransferase Inhibition causes Mitochondrial Iron Overload and Parthanatos in TIM17A-dependent Aggressive Lung Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11270646/
  61. f1000research.com f1000research.com
    A guide to selecting high-performing antibodies for Synaptotagmin-1 (Uniprot ID P21579) for use in western blot, immunoprecipitation, immunofluorescence and flow cytometry
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    f1000research.com/articles/13-817
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC11240082/
  63. f1000research.com f1000research.com
    A guide to selecting high-performing antibodies for S1PR1 (UniProt ID: P21453) for use in western blot, immunoprecipitation, and immunofluorescence
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    f1000research.com/articles/13-792
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    A guide to selecting high-performing antibodies for CSNK2A1 (UniProt ID: P68400) for use in western blot, immunoprecipitation and immunofluorescence
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    f1000research.com/articles/13-781
  65. Jun 2024
  66. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction
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    onlinelibrary.wiley.com/doi/10.1002/advs.202307695
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic Priming by Hypomethylation Enhances the Immunogenic Potential of Tolinapant in T-cell Lymphoma
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  68. May 2024
  69. www.researchsquare.com www.researchsquare.com
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  71. www.nature.com www.nature.com
    Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase
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    nature.com/articles/s41586-024-07318-y
  72. aacrjournals.org aacrjournals.org
    Molecular and pathological characterization of YAP1-expressing small cell lung cancer cell lines leads to reclassification as SMARCA4-deficient malignancies
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    aacrjournals.org/clincancerres/article/30/9/1846/743134/Molecular-and-Pathologic-Characterization-of-YAP1
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    Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations
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    Cetuximab–Toxin Conjugate and NPe6 with Light Enhanced Cytotoxic Effects in Head and Neck Squamous Cell Carcinoma In Vitro
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  75. Apr 2024
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for RNA-binding protein TIA1 for use in Western Blot, immunoprecipitation and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC11024596/
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    Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10993856/
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for Rab1A and Rab1B for use in Western Blot, immunoprecipitation and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC10979127/
  79. Mar 2024
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants
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    ncbi.nlm.nih.gov/pmc/articles/PMC10978866/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of high-performing antibodies for Vacuolar protein sorting-associated protein 35 (hVPS35) for use in Western Blot, immunoprecipitation and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC10905012/
  82. Feb 2024
  83. 52.53.155.43 52.53.155.43
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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal signals dominate gene expression signature scores that aim to describe cancer cell-intrinsic stemness or mesenchymality characteristics
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    ncbi.nlm.nih.gov/pmc/articles/PMC10885853/
  86. www.biorxiv.org www.biorxiv.org
    The Vps13-like protein BLTP2 is pro-survival and regulates phosphatidylethanolamine levels in the plasma membrane to maintain its fluidity and function
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    biorxiv.org/content/10.1101/2024.02.04.578804v1
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
  88. Jan 2024
  89. 52.53.155.43 52.53.155.43
    A guide to selecting high-performing antibodies for PLC-gamma-2 for use in Western Blot, immunoprecipitation and immunofluorescence
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10330305/
  91. f1000research.com f1000research.com
    A guide to selecting high-performing antibodies for Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D) for use in Western Blot, immunoprecipitation and immunofluorescence
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    f1000research.com/articles/13-1
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of high-performing antibodies for Apolipoprotein E for use in Western Blot and immunoprecipitation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10755264/
  93. Dec 2023
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of high-performing antibodies for Moesin for use in Western Blot, immunoprecipitation, and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC10724652/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality
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    ncbi.nlm.nih.gov/pmc/articles/PMC10722143/
  96. f1000research.com f1000research.com
    F1000Research Article: Identification of high-performing antibodies for Rab1A and Rab1B for use in Western Blot, immunoprecipitation and immunofluorescence.
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    f1000research.com/articles/12-1578
  97. Nov 2023
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications
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    ncbi.nlm.nih.gov/pmc/articles/PMC10666931/
  99. Oct 2023
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inducing Mitotic Catastrophe as a Therapeutic Approach to Improve Outcomes in Ewing Sarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10605681/
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    DHODH: A promising target in the treatment of T-Acute Lymphoblastic Leukemia
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  102. 52.53.155.43 52.53.155.43
    Preprints202309.2164.v1-html.html
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  103. Sep 2023
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for Coiled-coil-helix-coiled-coil-helix domain containing protein 10 (CHCHD10) for use in Western Blot, immunoprecipitation and immunofluorescence
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  105. Aug 2023
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    The identification of high-performing antibodies for Profilin-1 for use in Western blot, immunoprecipitation and immunofluorescence
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    Combination drug screen targeting glioblastoma core vulnerabilities reveals pharmacological synergisms
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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Integrative single-cell and bulk transcriptomes analyses identify intrinsic HNSCC subtypes with distinct prognoses and therapeutic vulnerabilities
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    BET Inhibitors Target the SCLC-N subtype of Small Cell Lung Cancer by Blocking NEUROD1 Transactivation
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  112. Jun 2023
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    The identification of high-preforming antibodies for Ubiquilin-2 for use in Western Blot, immunoprecipitation, and immunofluorescence
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    The identification of high-performing antibodies for TDP-43 for use in Western Blot, immunoprecipitation and immunofluorescence
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    An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
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    The identification of high-performing antibodies for Vacuolar protein sorting-associated protein 35 (hVPS35) for use in Western Blot, immunoprecipitation and immunofluorescence
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    The identification of high-performing antibodies for Coiled-coil-helix-coiled-coil-helix domain containing protein 10 (CHCHD10) for use in Western Blot, immunoprecipitation and immunofluorescence
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    The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence
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    The identification of high-performing antibodies for Midkine for use in Western blot and immunoprecipitation
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  121. May 2023
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer
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  123. Apr 2023
  124. aacrjournals.org aacrjournals.org
    Targeting ULK1 decreases interferon-γ-mediated resistance to immune checkpoint inhibitors
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    Bayesian Machine Learning Enables Identification of Transcriptional Network Disruptions Associated with Drug-Resistant Prostate Cancer
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  126. www.sciencedirect.com www.sciencedirect.com
    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
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    Analysis of Cancer Genomic Amplifications Identifies Druggable Collateral Dependencies within the Amplicon
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  128. Mar 2023
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    F1000Research Article: The identification of high-performing antibodies for Secreted frizzled-related protein 1 (sFRP-1) for use in Western Blot and immunoprecipitation.
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  131. Feb 2023
  132. www.sciencedirect.com www.sciencedirect.com
    UHRF1/DNMT1-MZF1 axis-modulated intragenic site-specific CpGI methylation confers divergent expression and opposing functions of PRSS3 isoforms in lung cancer
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    Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endo180 (MRC2) Antibody–Drug Conjugate for the Treatment of Sarcoma
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  136. Dec 2022
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  138. Nov 2022
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    FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
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  140. Sep 2022
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    Experimental reproducibility limits the correlation between mRNA and protein abundances in tumor proteomic profiles
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins
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  143. Aug 2022
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    F1000Research Article: Identification of highly specific antibodies for Serine/threonine-protein kinase TBK1 for use in immunoblot, immunoprecipitation and immunofluorescence.
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  145. Jun 2022
  146. aacrjournals.org aacrjournals.org
    Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML
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  147. Mar 2022
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    The mTOR chromatin-bound interactome in prostate cancer
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective modulation of a pan-essential protein as a therapeutic strategy in cancer
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  150. Feb 2022
  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sesquiterpene Lactones Potentiate Olaparib-Induced DNA Damage in p53 Wildtype Cancer Cells
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  152. Jan 2022
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    A functional taxonomy of tumor suppression in oncogenic KRAS-driven lung cancer
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  154. Dec 2021
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    Uncovering drug repurposing candidates for head and neck cancers: insights from systematic pharmacogenomics data analysis
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  156. Sep 2021
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    Comprehensive prediction of robust synthetic lethality between paralog pairs in cancer cell lines
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  158. Jun 2021
  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition
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  160. Mar 2021
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    Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia
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  162. Feb 2021
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    Super-Enhancer Redistribution as a Mechanism of Broad Gene Dysregulation in Repeatedly Drug-Treated Cancer Cells
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  164. Sep 2020
  165. elifesciences.org elifesciences.org
    Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions
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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN and DNA-PK determine sensitivity and recovery in response to WEE1 inhibition in human breast cancer
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