85 Matching Annotations
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  2. pubs.acs.org pubs.acs.org
    A SMUG1 Inhibitor Modulates the Excision of Pyrimidine DNA Damage
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    pubs.acs.org/doi/10.1021/acsmedchemlett.6c00051
  3. Jul 2026
  4. www.biorxiv.org www.biorxiv.org
    The MIRO1-BAX Complex Dictates Life and Death at the Mitochondrial Gate
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    biorxiv.org/content/10.64898/2026.06.29.733391v1
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    Ubiquitin-like proteins NEDD8 and SUMO2 control epithelial homeostasis, regeneration, and inflammation
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    science.org/doi/10.1126/science.aeb3900
  6. Jun 2026
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    Phase II trial of cabozantinib in combination with nivolumab for advanced extrapancreatic neuroendocrine tumors (epNET)
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    aacrjournals.org/clincancerres/article/32/3/540/772029/Phase-II-Trial-of-Cabozantinib-in-Combination-with
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    Saxiphilin is a broad-spectrum toxin sponge for C13-modified saxitoxins
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    sciencedirect.com/science/article/pii/S0969212626001541
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    A SMUG1 Inhibitor Modulates the Excision of Pyrimidine DNA Damage
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    pubs.acs.org/doi/10.1021/acsmedchemlett.6c00051
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chemical Modulation of Miro1 Alleviates Cell-Type-Specific Vulnerabilities in Friedreich’s Ataxia
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    pmc.ncbi.nlm.nih.gov/articles/PMC13251323/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In Depth Characterization of the Promoter Proximal Proteome of Single Copy Locus FOXP2
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    pmc.ncbi.nlm.nih.gov/articles/PMC13227211/
  12. May 2026
  13. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70510
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    In Vivo mRNA Delivery to the Lung Vascular Endothelium by Dicationic Charge-Altering Releasable Transporters
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    pmc.ncbi.nlm.nih.gov/articles/PMC13186261/
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    Zero-shot design of a de novo metalloenzyme
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    biorxiv.org/content/10.64898/2026.04.23.720277v1
  16. Mar 2026
  17. www.nature.com www.nature.com
    Biomolecular condensates mediate C–N bond formation
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    nature.com/articles/s41589-026-02169-2
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Active maintenance of meiosis-specific chromosome structures in Caenorhabditis elegans by the deubiquitinase DUO-1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012089/
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    Saxiphilin is a broad-spectrum toxin sponge for C13-modified saxitoxins
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    biorxiv.org/content/10.64898/2026.03.10.710854v1
  20. pubs.acs.org pubs.acs.org
    Site-Specific Labeling of PD-L1 Fab through Disulfide Rebridging for ImmunoPET Imaging
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    pubs.acs.org/doi/full/10.1021/cbmi.6c00022
  21. Feb 2026
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Small-Molecule Activator of SMUG1 Enhances Repair of Pyrimidine Lesions in DNA
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    pmc.ncbi.nlm.nih.gov/articles/PMC11846699/
  23. Jan 2026
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Active maintenance of meiosis-specific chromosome structures in C. elegans by the deubiquitinase DUO-1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12802401/
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    EcDNA-borne structural variants drive oncogenic fusion transcript amplification
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    sciencedirect.com/science/article/pii/S0092867425014229
  26. Dec 2025
  27. pubs.aip.org pubs.aip.org
    Repetitive proteins that undergo large conformational changes evade structural prediction algorithms
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    pubs.aip.org/aip/jcp/article/163/22/224906/3374611/Repetitive-proteins-that-undergo-large
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Convenient syntheses of isotopically labeled pyrimidine 2´-deoxynucleosides and their 5-hydroxy oxidation products
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    pmc.ncbi.nlm.nih.gov/articles/PMC12146429/
  29. Nov 2025
  30. www.biorxiv.org www.biorxiv.org
    RNA switch model for localization and translation of the myelin basic protein mRNA
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    biorxiv.org/content/10.1101/2025.11.19.689361v1
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    A chemogenetic ligand-receptor pair for voltage-gated sodium channel subtype-selective inhibition
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    biorxiv.org/content/10.1101/2025.11.03.686046v1
  32. Oct 2025
  33. pubs.acs.org pubs.acs.org
    ApoE is Secreted as a Lipid Nanoparticle by Mammalian Cells: Implications for Alzheimer’s Disease Pathogenesis
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    pubs.acs.org/doi/10.1021/acs.biochem.5c00503
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    Ballistic Microscopy (BaM)
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    biorxiv.org/content/10.1101/2025.10.07.681030v1
  35. pubs.acs.org pubs.acs.org
    Cascade Mechanochemical Transformation of a Benzobarrelane Polymer
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    pubs.acs.org/doi/full/10.1021/jacs.5c14494
  36. pubs.acs.org pubs.acs.org
    Unidirectional Chain Transfer of Enol Ethers Yields Heterotelechelic Degradable Poly(Enol Ether)
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    pubs.acs.org/doi/full/10.1021/acsmacrolett.5c00524
  37. Aug 2025
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combinatory Treatment to Alleviate Cellular Stress and Improve Skeletal Muscle Phenotype in Spinal Muscular Atrophy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12295002/
  39. Jul 2025
  40. www.mdpi.com www.mdpi.com
    Room-Temperature Plasma Hydrogenation of Fatty Acid Methyl Esters (FAMEs)
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    mdpi.com/2227-9717/13/8/2333
  41. 52.53.155.43 52.53.155.43
    2025.07.10.663086v1.full-html.html
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    SNARE disassembly requires Sec18/NSF side loading
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    nature.com/articles/s41594-025-01590-w
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Light-controlled Intracellular Synthesis of Poly(luciferin) Polymers Induces Cell Paraptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12221825/
  44. Jun 2025
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis
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  46. May 2025
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Plasma Proteomics of the Fontan Circulation Reveal Signatures of Oxidative Stress and Cell Death
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    pmc.ncbi.nlm.nih.gov/articles/PMC12084025/
  48. Apr 2025
  49. www.sciencedirect.com www.sciencedirect.com
    DNA binding and mitotic phosphorylation protect polyglutamine proteins from assembly formation
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    sciencedirect.com/science/article/pii/S0092867425003496
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    A multi-institutional investigation of psilocybin’s effects on mouse behavior
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    biorxiv.org/content/10.1101/2025.04.08.647810v1
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multilayered HIV-1 resistance in HSPCs through CCR5 Knockout and B cell secretion of HIV-inhibiting antibodies
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    pmc.ncbi.nlm.nih.gov/articles/PMC11958643/
  52. Jan 2025
  53. pubs.acs.org pubs.acs.org
    Toughening Poly(lactic acid) without Compromise – Statistical Copolymerization with a Bioderived Bicyclic Lactone
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    pubs.acs.org/doi/full/10.1021/jacs.4c15697
  54. Dec 2024
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11657531/
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    Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11581111/
  57. Nov 2024
  58. pubs.acs.org pubs.acs.org
    Bridging the Translation of ICG-1-Maltotriose: A Multimodal Sensor for Monitoring and Detecting Bacterial Infections
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    pubs.acs.org/doi/10.1021/acssensors.3c02005
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    Fluorination Affects the Force Sensitivity and Nonequilibrium Dynamics of the Mechanochemical Unzipping of Ladderanes
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    pubs.acs.org/doi/full/10.1021/jacs.4c11912
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Repurposing mebendazole against triple-negative breast cancer leptomeningeal disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC10889063/
  61. Sep 2024
  62. pubs.acs.org pubs.acs.org
    Biguanide-Vancomycin Conjugates are Effective Broad-Spectrum Antibiotics against Actively Growing and Biofilm-Associated Gram-Positive and Gram-Negative ESKAPE Pathogens and Mycobacteria
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    pubs.acs.org/doi/10.1021/jacs.4c06520
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sec18 side-loading is essential for universal SNARE recycling across cellular contexts
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    ncbi.nlm.nih.gov/pmc/articles/PMC11384006/
  64. Aug 2024
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Saponin nanoparticle adjuvants incorporating Toll-like receptor agonists drive distinct immune signatures and potent vaccine responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC11305391/
  66. pubs.acs.org pubs.acs.org
    Influence of Autoclave Liner on Polyethylene Hydrogenolysis Selectivity
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    pubs.acs.org/doi/full/10.1021/acssusresmgt.4c00112
  67. pubs.acs.org pubs.acs.org
    Bridging the Translation of ICG-1-Maltotriose: A Multimodal Sensor for Monitoring and Detecting Bacterial Infections
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    pubs.acs.org/doi/10.1021/acssensors.3c02005
  68. pubs.acs.org pubs.acs.org
    Vancomycin-Polyguanidino Dendrimer Conjugates Inhibit Growth of Antibiotic-Resistant Gram-Positive and Gram-Negative Bacteria and Eradicate Biofilm-Associated S. aureus
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    pubs.acs.org/doi/full/10.1021/acsinfecdis.3c00168
  69. Jul 2024
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of protein aggregates in the aging vertebrate brain with prion-like and phase-separation properties
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure and topography of the synaptic V-ATPase–synaptophysin complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC11269182/
  72. Jun 2024
  73. www.biorxiv.org www.biorxiv.org
    Peptide sequencing via reverse translation of peptides into DNA
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    biorxiv.org/content/10.1101/2024.05.31.596913v1
  74. May 2024
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P66 is a bacterial mimic of CD47 that binds the anti-phagocytic receptor SIRPα and facilitates macrophage evasion by Borrelia burgdorferi
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    ncbi.nlm.nih.gov/pmc/articles/PMC11092639/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repurposing mebendazole against triple-negative breast cancer CNS metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11093727/
  77. Apr 2024
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Numb positively regulates Hedgehog signaling at the ciliary pocket
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  79. Feb 2024
  80. www.sciencedirect.com www.sciencedirect.com
    Impact of high-fat diet on cognitive behavior and central and systemic inflammation with aging and sex differences in mice
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    sciencedirect.com/science/article/pii/S0889159124002617
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A toxic environment selects for specialist microbiome in poison frogs
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802471/
  82. Jan 2024
  83. pubs.acs.org pubs.acs.org
    Mechanochemistry of Pterodactylane
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    pubs.acs.org/doi/10.1021/jacs.3c11293
  84. www.sciencedirect.com www.sciencedirect.com
    DNA-guided transcription factor cooperativity shapes face and limb mesenchyme
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    sciencedirect.com/science/article/pii/S0092867423014381
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conjugation of Vancomycin with a Single Arginine Improves Efficacy Against Mycobacteria by More Effective Peptidoglycan Targeting
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    ncbi.nlm.nih.gov/pmc/articles/PMC10783851/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plasmodium falciparum exploits CD44 as a coreceptor for erythrocyte invasion
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    A lethal mitonuclear incompatibility in complex I of natural hybrids
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    link.springer.com/article/10.1038/s41586-023-06895-8
  88. Dec 2023
  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Beta-2 adrenergic receptor agonism alters astrocyte phagocytic activity and has potential applications to psychiatric disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC10689618/
  90. Sep 2023
  91. www.science.org www.science.org
    An antibody-based molecular switch for continuous small-molecule biosensing
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    science.org/doi/10.1126/sciadv.adh4978
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An antibody-based molecular switch for continuous small-molecule biosensing
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    ncbi.nlm.nih.gov/pmc/articles/PMC10516488/
  93. www.nature.com www.nature.com
    Pervasive transcriptome interactions of protein-targeted drugs
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    nature.com/articles/s41557-023-01309-8
  94. Aug 2023
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Host MOSPD2 enrichment at the parasitophorous vacuole membrane varies between Toxoplasma strains and involves complex interactions
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    ncbi.nlm.nih.gov/pmc/articles/PMC10449529/
  96. Jul 2023
  97. www.nature.com www.nature.com
    Reversible 2′-OH acylation enhances RNA stability
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    nature.com/articles/s41557-023-01246-6
  98. Jun 2023
  99. 52.53.155.43 52.53.155.43
    Antagonistic Insulin Derivative Suppresses Insulin-Induced Hypoglycemia
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    52.53.155.43/a39d77c3c1b0615359897ccf4b81d40d6d1d47cf/acs.jmedchem.3c00280-html.html
  100. www.biorxiv.org www.biorxiv.org
    DNA-guided transcription factor cooperativity shapes face and limb mesenchyme
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    biorxiv.org/content/10.1101/2023.05.29.541540v1
  101. Apr 2023
  102. www.biorxiv.org www.biorxiv.org
    Plasmodium falciparum exploits CD44 as a co-receptor for erythrocyte invasion
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    biorxiv.org/content/10.1101/2023.04.12.536503v1
  103. Mar 2023
  104. www.biorxiv.org www.biorxiv.org
    An Antibody-Based Molecular Switch for Continuous Biosensing
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    biorxiv.org/content/10.1101/2023.03.07.531602v1
  105. Jan 2023
  106. www.sciencedirect.com www.sciencedirect.com
    Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells
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    sciencedirect.com/science/article/pii/S0021925822012911
  107. Sep 2022
  108. www.nature.com www.nature.com
    CNS myelination requires VAMP2/3-mediated membrane expansion in oligodendrocytes
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    nature.com/articles/s41467-022-33200-4
  109. Aug 2022
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The interaction of SWI/SNF with the ribosome regulates translation and confers sensitivity to translation pathway inhibitors in cancers with complex perturbations
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    ncbi.nlm.nih.gov/pmc/articles/PMC9379364/
  111. May 2022
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PEX19 Coordinates Neutral Lipid Storage in Cells in a Peroxisome-Independent Fashion
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    ncbi.nlm.nih.gov/pmc/articles/PMC9086359/
  113. Apr 2022
  114. www.sciencedirect.com www.sciencedirect.com
    The cargo adaptor protein CLINT1 is phosphorylated by the Numb-associated kinase BIKE and mediates dengue virus infection
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    sciencedirect.com/science/article/pii/S0021925822003969
  115. www.biorxiv.org www.biorxiv.org
    A Lethal Genetic Incompatibility between Naturally Hybridizing Species in Mitochondrial Complex I
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    biorxiv.org/content/10.1101/2021.07.13.452279v2
  116. Nov 2021
  117. www.sciencedirect.com www.sciencedirect.com
    RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development
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    sciencedirect.com/science/article/pii/S0092867421012320
  118. Oct 2021
  119. pubs.acs.org pubs.acs.org
    Reversible Click Chemistry Tag for Universal Proteome Sample Preparation for Top-Down and Bottom-Up Analysis
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    pubs.acs.org/doi/10.1021/acs.jproteome.1c00443
  120. Sep 2021
  121. pubs.acs.org pubs.acs.org
    Reversible Click Chemistry Tag for Universal Proteome Sample Preparation for Top-Down and Bottom-Up Analysis
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    pubs.acs.org/doi/10.1021/acs.jproteome.1c00443
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A mitochondrial membrane-bridging machinery mediates signal transduction of intramitochondrial oxidation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8460615/
  123. Jun 2021
  124. www.sciencedirect.com www.sciencedirect.com
    Age-related neuroinflammation and pathology in the locus coeruleus and hippocampus: beta-adrenergic antagonists exacerbate impairment of learning and memory in aged mice
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    sciencedirect.com/science/article/pii/S0197458021002062