90 Matching Annotations
  1. Last 7 days
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    A first-in-class small-molecule inhibitor targeting AVIL exhibits safety and antitumor efficacy in preclinical models of glioblastoma
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    science.org/doi/10.1126/scitranslmed.adt1211
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineering Enhanced Immunogenicity of Surface-Displayed Immunogens in a Killed Whole-Cell Genome-Reduced Bacterial Vaccine Platform Using Class I Viral Fusion Peptides
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    pmc.ncbi.nlm.nih.gov/articles/PMC12846404/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The LMO2-LDB1-TAL1 complex regulates transcription networks in acute myeloid leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12835595/
  5. Jan 2026
  6. www.biorxiv.org www.biorxiv.org
    C4BP occludes the non-opsonic interaction of Neisseria gonorrhoeae with human neutrophil CEACAMs
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    biorxiv.org/content/10.64898/2026.01.19.700458v1
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    Methanogenic archaea bolster mucosal homeostasis and protect from colitis
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    biorxiv.org/content/10.64898/2026.01.19.700430v1
  8. Dec 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PCSK5M452I is a recessive hypomorph exclusive to MCF10DCIS.com cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12671455/
  10. Nov 2025
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    Metabolic network analysis of Crohn’s disease reveals sex- and age-specific cellular phenotypes
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    sciencedirect.com/science/article/pii/S2405471225002807
  12. 54.241.53.176 54.241.53.176
    2025.11.06.686987v1.full-html.html
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  13. Oct 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Co-Conservation of synaptic gene expression and circuitry in collicular neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC12528736/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Experimental TET2 Clonal Hematopoiesis Predisposes to Renal Hypertension Through an Inflammasome-Mediated Mechanism
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    pmc.ncbi.nlm.nih.gov/articles/PMC11519839/
  16. Sep 2025
  17. www.biorxiv.org www.biorxiv.org
    Cadherin-11 integrates Piezo1 and interleukin-6 signaling to promote fibroblast activation
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    biorxiv.org/content/10.1101/2025.09.16.674909v1
  18. Aug 2025
  19. www.sciencedirect.com www.sciencedirect.com
    Prevalence of Adverse Drug Reactions: Comparing Crotalidae Immune Polyvalent Antivenoms F(ab’)2 and F(ab) in a Galactose-alpha-1,3-galactose (alpha-gal) Endemic Area
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    sciencedirect.com/science/article/pii/S019606442501039X
  20. Jul 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanically Tunable Poly(Ethylene Glycol) Diacrylate Hydrogels Reveal Stiffness‐Related Impairments in Capillary Sprouting in Experimental Lung Fibrosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12271678/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification and characterization of functional and trans-dominant negative HERV-K (HML-2) Rec proteins encoded in the human genome
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    pmc.ncbi.nlm.nih.gov/articles/PMC12265724/
  23. www.medrxiv.org www.medrxiv.org
    From Breath to Brain: NICU Respiratory Interventions and Bedside Brain Signal Entropy Predict Later Autism Risk
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    medrxiv.org/content/10.1101/2025.07.07.25331007v1
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of DHX36/G4R1, a G4 resolvase, drives genome instability and regulates innate immune gene expression in cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214017/
  25. Jun 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety
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    pmc.ncbi.nlm.nih.gov/articles/PMC12186539/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synergistic activity of simvastatin and irinotecan chemotherapy against glioblastoma converges on TGF-β signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12263772/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lacritin cleavage-potentiated targeting of iron - respiratory reciprocity promotes bacterial death
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    pmc.ncbi.nlm.nih.gov/articles/PMC12147183/
  29. May 2025
  30. elifesciences.org elifesciences.org
    DNA replication in primary hepatocytes without the six-subunit ORC
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    elifesciences.org/articles/102915
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rev-RRE activity modulates HIV-1 replication and latency reactivation: Implications for viral persistence and cure strategies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12080775/
  32. Mar 2025
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PCSK5M452I is a recessive hypomorph exclusive to MCF10DCIS.com cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11908202/
  34. Jan 2025
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tet2-mediated clonal hematopoiesis modestly improves neurological deficits and is associated with inflammation resolution in the subacute phase of experimental stroke
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    pmc.ncbi.nlm.nih.gov/articles/PMC11685025/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rev-RRE activity modulates HIV-1 replication and latency reactivation: Implications for viral persistence and cure strategies
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    pmc.ncbi.nlm.nih.gov/articles/PMC11741256/
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Characterizing Microglial Signaling Dynamics During Inflammation Using Single-Cell Mass Cytometry
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    onlinelibrary.wiley.com/doi/10.1002/glia.24670
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Patient-derived response estimates from zero-passage organoids of luminal breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11687200/
  39. elifesciences.org elifesciences.org
    DNA replication in primary hepatocytes without the six-subunit ORC
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    elifesciences.org/reviewed-preprints/102915
  40. Dec 2024
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-dimensional spectral flow cytometry of activation and phagocytosis by peripheral human polymorphonuclear leukocytes
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    A single-cell mass cytometry-based atlas of the developing mouse brain
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    nature.com/articles/s41593-024-01786-1
  43. www.biorxiv.org www.biorxiv.org
    The IL-33/ST2 signaling axis drives pathogenesis in acute SARS-CoV-2 infection
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    biorxiv.org/content/10.1101/2024.11.27.625579v1
  44. Aug 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tissue- and Temporal-Dependent Dynamics of Myeloablation in Response to Gemcitabine Chemotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11352862/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunotherapy with biodegradable nanoparticles encapsulating the oligosaccharide galactose-alpha-1,3-galactose enhance immune tolerance against alpha-gal sensitization in a murine model of alpha-gal syndrome
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    Poly I:C vaccination drives transient CXCL9 expression near B cell follicles in the lymph node through type-I and type-II interferon signaling
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    sciencedirect.com/science/article/pii/S1043466624002345
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A high-dimensional platform for observing neutrophil–parasite interactions
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    ncbi.nlm.nih.gov/pmc/articles/PMC11302258/
  49. www.biorxiv.org www.biorxiv.org
    Characterizing microglial signaling dynamics during inflammation using single-cell mass cytometry
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    biorxiv.org/content/10.1101/2024.07.27.605444v1
  50. Jul 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    B cells secrete functional antigen-specific IgG antibodies on extracellular vesicles
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    ncbi.nlm.nih.gov/pmc/articles/PMC11266516/
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    A Thy-1–negative immunofibroblast population emerges as a key determinant of fibrotic outcomes to biomaterials
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    science.org/doi/10.1126/sciadv.adf2675
  53. journals.asm.org journals.asm.org
    A high-dimensional platform for observing neutrophil–parasite interactions
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    journals.asm.org/doi/10.1128/spectrum.00472-24
  54. journals.plos.org journals.plos.org
    Dual species transcriptomics reveals conserved metabolic and immunologic processes in interactions between human neutrophils and Neisseria gonorrhoeae
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    journals.plos.org/plospathogens/article
  55. Jun 2024
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Thy-1–negative immunofibroblast population emerges as a key determinant of fibrotic outcomes to biomaterials
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    ncbi.nlm.nih.gov/pmc/articles/PMC11177936/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Persistent dysbiosis of duodenal microbiota in patients with controlled pediatric Crohn’s disease after resolution of inflammation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11148174/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Partitioning to ordered membrane domains regulates the kinetics of secretory traffic
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    ncbi.nlm.nih.gov/pmc/articles/PMC11152573/
  59. May 2024
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neisseria gonorrhoeae scavenges host sialic acid for Siglec-mediated, complement-independent suppression of neutrophil activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11078009/
  61. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Conjugation of IL-33 to Microporous Annealed Particle Scaffolds Enhances Type 2-Like Immune Responses In Vitro and In Vivo
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    onlinelibrary.wiley.com/doi/10.1002/adhm.202400249
  62. elifesciences.org elifesciences.org
    Partitioning to ordered membrane domains regulates the kinetics of secretory traffic
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    elifesciences.org/reviewed-preprints/89306
  63. Apr 2024
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of TET2 increases B-1 cell number and IgM production while limiting CDR3 diversity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11004297/
  65. www.biorxiv.org www.biorxiv.org
    Distinct Type 1 Immune Networks Underlie the Severity of Restrictive Lung Disease after COVID-19
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    biorxiv.org/content/10.1101/2024.04.03.587929v1
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Colonization during a key developmental window reveals microbiota-dependent shifts in growth and immunity during undernutrition
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    ncbi.nlm.nih.gov/pmc/articles/PMC11003143/
  67. Mar 2024
  68. link.springer.com link.springer.com
    Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism
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    link.springer.com/article/10.1186/s13059-024-03212-y
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Iron - Respiratory Reciprocity Promotes Bacterial Death
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    ncbi.nlm.nih.gov/pmc/articles/PMC10925246/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of the Uty epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure
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    ncbi.nlm.nih.gov/pmc/articles/PMC11343478/
  71. Feb 2024
  72. 52.53.155.43 52.53.155.43
    Obesogenic diet disrupts tissue specific mitochondrial gene signatures in the artery and capillary endothelium
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    52.53.155.43/a6a23a8c2d70229624aa8b2579ca10bb064fad6f/dunaway-et-al-2024-obesogenic-diet-disrupts-tissue-specific-mitochondrial-gene-signatures-in-the-artery-and-capillary-html.html
  73. www.biorxiv.org www.biorxiv.org
    UBA1-CDK16: A Sex-Specific Chimeric RNA and Its Role in Immune Sexual Dimorphism
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    biorxiv.org/content/10.1101/2024.02.13.580120v1
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development and implementation of a Type I-C CRISPR-based programmable repression system for Neisseria gonorrhoeae
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    ncbi.nlm.nih.gov/pmc/articles/PMC10865793/
  75. journals.asm.org journals.asm.org
    Development and implementation of a Type I-C CRISPR-based programmable repression system for Neisseria gonorrhoeae
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    journals.asm.org/doi/10.1128/mbio.03025-23
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neisseria gonorrhoeae scavenges host sialic acid for Siglec-mediated, complement-independent suppression of neutrophil activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10827150/
  77. www.biorxiv.org www.biorxiv.org
    Mouse Model of Heart Attack and Stroke Shows Improved Survival with MPO Inhibition
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    biorxiv.org/content/10.1101/2023.10.06.561304v1
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    Nanosphere pharmacodynamics improves safety of immunostimulatory cytokine therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831265/
  79. Dec 2023
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evaluating vaccine-elicited antibody activities against Neisseria gonorrhoeae: cross-protective responses elicited by the 4CMenB meningococcal vaccine
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    ncbi.nlm.nih.gov/pmc/articles/PMC10715150/
  81. Nov 2023
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effects
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    ncbi.nlm.nih.gov/pmc/articles/PMC10635799/
  83. www.biorxiv.org www.biorxiv.org
    Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety
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    biorxiv.org/content/10.1101/2023.10.31.564990v1
  84. www.sciencedirect.com www.sciencedirect.com
    Lactobacillus from the Altered Schaedler Flora maintain IFNγ homeostasis to promote behavioral stress resilience
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    sciencedirect.com/science/article/pii/S0889159123003343
  85. Sep 2023
  86. 52.53.155.43 52.53.155.43
    Rev-Rev Response Element Activity Selection Bias at the HIV Transmission Bottleneck
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    52.53.155.43/ab56c43d6decb72d9bd1625080f569a67fadb679/ofad486-html.html
  87. Aug 2023
  88. www.biorxiv.org www.biorxiv.org
    Evaluating vaccine-elicited antibody activities against Neisseria gonorrhoeae: cross-protective responses elicited by the 4CMenB meningococcal vaccine
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    biorxiv.org/content/10.1101/2023.08.03.551882v1
  89. Jul 2023
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Colonization during a key developmental window reveals microbiota-dependent shifts in growth and immunity during undernutrition
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    ncbi.nlm.nih.gov/pmc/articles/PMC10350093/
  91. dx.doi.org dx.doi.org
    Phagocytosis via complement receptor 3 enables microbes to evade killing by neutrophils
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    dx.doi.org/10.1093/jleuko/qiad028
  92. www.biorxiv.org www.biorxiv.org
    Loss of endothelial cell heterogeneity in arteries after obesogenic diet
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    biorxiv.org/content/10.1101/2023.06.23.546320v1
  93. Jun 2023
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histotripsy ablation for the treatment of feline injection site sarcomas: a first-in-cat in vivo feasibility study
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    ncbi.nlm.nih.gov/pmc/articles/PMC10278555/
  95. 52.53.155.43 52.53.155.43
    Secondary bile acids function through the vitamin D receptor in myeloid progenitors to promote myelopoiesis
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    52.53.155.43/7c36fda2245bc32de5518194fb76180bc1ab318d/bloodadvances.2022009618-html.html
  96. www.biorxiv.org www.biorxiv.org
    Novel TRPM7 inhibitors with potent anti-inflammatory effects in vivo
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    biorxiv.org/content/10.1101/2023.05.22.541802v1
  97. www.sciencedirect.com www.sciencedirect.com
    Sexual dimorphism in the dorsal root ganglia of neonatal mice identified by protein expression profiling with single-cell mass cytometry
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    sciencedirect.com/science/article/pii/S104474312300060X
  98. Apr 2023
  99. www.biorxiv.org www.biorxiv.org
    Partitioning to ordered membrane domains regulates the kinetics of secretory traffic
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    biorxiv.org/content/10.1101/2023.04.18.537395v2
  100. www.biorxiv.org www.biorxiv.org
    Rev-Rev Response Element Activity Selection Bias at the HIV Transmission Bottleneck
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    biorxiv.org/content/10.1101/2023.04.05.535732v1
  101. www.sciencedirect.com www.sciencedirect.com
    Regadenoson Reduces Soluble Receptor for Advanced Glycation End-Products in Lung Recipients
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    sciencedirect.com/science/article/pii/S0003497523002783
  102. www.nature.com www.nature.com
    Priming a vascular-selective cytokine response permits CD8+ T-cell entry into tumors
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    nature.com/articles/s41467-023-37807-z
  103. Mar 2023
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neisseria gonorrhoeae co-opts C4b-binding protein to enhance complement-independent survival from neutrophils
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    ncbi.nlm.nih.gov/pmc/articles/PMC10013916/
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ANKLE1 cleaves mitochondrial DNA and contributes to cancer risk by promoting apoptosis resistance and metabolic dysregulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9977882/
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BMP-6 promotes type 2 immune response during enhancement of rat mandibular bone defect healing
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    ncbi.nlm.nih.gov/pmc/articles/PMC9950738/
  107. Feb 2023
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The activity of the aryl hydrocarbon receptor in T cells tunes the gut microenvironment to sustain autoimmunity and neuroinflammation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9928083/
  109. Nov 2022
  110. www.nature.com www.nature.com
    HIV-1 Rev-RRE functional activity in primary isolates is highly dependent on minimal context-dependent changes in Rev
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    nature.com/articles/s41598-022-21714-2
  111. Oct 2022
  112. www.nature.com www.nature.com
    A developmental atlas of somatosensory diversification and maturation in the dorsal root ganglia by single-cell mass cytometry
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    nature.com/articles/s41593-022-01181-8
  113. Sep 2022
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437978/
  115. Jul 2022
  116. www.science.org www.science.org
    Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality
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    science.org/doi/10.1126/science.abn3100
  117. www.medrxiv.org www.medrxiv.org
    Fecal microbiota transplantation increases colonic IL-25 and dampens tissue inflammation in patients with recurrent Clostridioides difficile
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    medrxiv.org/content/10.1101/2021.07.16.21260643v1
  118. journals.asm.org journals.asm.org
    Fecal Microbiota Transplantation Increases Colonic IL-25 and Dampens Tissue Inflammation in Patients with Recurrent Clostridioides difficile
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    journals.asm.org/doi/10.1128/mSphere.00669-21
  119. Jun 2022
  120. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cluster Analysis of Nasal Cytokines During Rhinovirus Infection Identifies Different Immunophenotypes in Both Children and Adults with Allergic Asthma
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    onlinelibrary.wiley.com/doi/10.1111/cea.14176
  121. Apr 2022
  122. www.biorxiv.org www.biorxiv.org
    ANKLE1 cleaves mitochondrial DNA and contributes to cancer risk by driving the Warburg effect and apoptosis resistance
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    biorxiv.org/content/10.1101/2021.10.27.466184v1
  123. Nov 2021
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8551335/
  125. Sep 2021
  126. www.mdpi.com www.mdpi.com
    A Novel Monoclonal Antibody Targeting Cancer-Specific Plectin Has Potent Antitumor Activity in Ovarian Cancer
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    mdpi.com/2073-4409/10/9/2218/htm