83 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dissection of Gαs and Hedgehog Signaling Cross-talk Reveals Therapeutic Opportunities to Target Hedgehog-Dependent Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC13055637/
  3. Mar 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FASN Inhibition Enhances the Efficacy of Chemotherapy in Colorectal Cancer by Inhibiting the DNA Damage Response
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    pmc.ncbi.nlm.nih.gov/articles/PMC13007557/
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    Human pluripotent stem cell-derived atrioventricular node-like pacemaker cells exhibit biological conduction bridge properties
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    sciencedirect.com/science/article/pii/S1934590926001104
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Multi-Step Immune-Competent Genetically Engineered Mouse Model Reveals Phenotypic Plasticity in Uveal Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12974268/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Corticotropin-Releasing Factor Release From a Unique Subpopulation of Accumbal Neurons Constrains Action-Outcome Acquisition in Reward Learning
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    pmc.ncbi.nlm.nih.gov/articles/PMC11839403/
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    Potentiating dendritic cell immunotherapy by interrupting the Semaphorin 4D-induced immune-suppressive barrier
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    sciencedirect.com/science/article/pii/S2211124726001282
  9. Feb 2026
  10. www.medrxiv.org www.medrxiv.org
    Acellular Adipose Tissue promotes anti-fibrotic remodeling in Phase II Study
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    medrxiv.org/content/10.64898/2026.02.04.26345214v1
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    1-s2.0-S2589004226002336-main-html.html
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    Inhibition of focal adhesion kinase impairs tumor formation and preserves hearing in a murine model of NF2-related schwannomatosis
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    science.org/doi/10.1126/sciadv.ady8382
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nivolumab and Relatlimab for the treatment of patients with unresectable or metastatic mismatch repair proficient colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12456301/
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    Inhibition of focal adhesion kinase impairs tumor formation and preserves hearing in a murine model of NF2-related schwannomatosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12857737/
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    B cell-intrinsic IL-2 signaling regulates inflammation by promoting IL-10 expression in CD25+ age-associated B cells
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    sciencedirect.com/science/article/pii/S1074761326000373
  16. Jan 2026
  17. www.biorxiv.org www.biorxiv.org
    System-wide profiling reveals metabolic alterations in a G2019S LRRK2 knockin mouse model of Parkinson’s disease: systemic depletion of pyrimidine nucleosides
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    biorxiv.org/content/10.64898/2025.12.31.697225v1
  18. Dec 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intratumoral three-cell-type clusters are a conserved feature of endogenous antitumor immunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12707859/
  20. 54.241.53.176 54.241.53.176
    2025.12.05.692494.full-html.html
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  21. Oct 2025
  22. www.tandfonline.com www.tandfonline.com
    Internalized SNCA/α-synuclein fibrils become truncated and resist degradation in neurons while glial cells rapidly degrade SNCA fibrils
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    tandfonline.com/doi/abs/10.1080/15548627.2025.2579147
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interactions Between Ploidy and Resource Availability Shape Clonal Evolution in Glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12261341/
  24. Sep 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of a First-in-Class Click Chemistry–Based Cancer Therapeutic, from Preclinical Evaluation to a First-in-Human Dose Escalation Clinical Trial
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  26. Aug 2025
  27. app.jove.com app.jove.com
    SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments
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    app.jove.com/t/68746/scaned-an-open-source-skin-segmentation-macro-for-semi-automated-cell
  28. Jul 2025
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    Asynchronous aging and turnover of human circulating and tissue-resident memory T cells across sites
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  31. Jun 2025
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    Siglec ligand immunohistochemistry reveals association with immune exclusion and survival
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  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    P4HA1 Mediates Hypoxia-Induced Invasion in Human Pancreatic Cancer Organoids
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  35. May 2025
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    Cell-death pathways and tau-associated neuronal vulnerability in Alzheimer’s disease
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  38. Apr 2025
  39. pathsocjournals.onlinelibrary.wiley.com pathsocjournals.onlinelibrary.wiley.com
    Activated immune infiltrates expand opportunities for targeted therapy in p53-abnormal endometrial carcinoma
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    pathsocjournals.onlinelibrary.wiley.com/doi/10.1002/path.6429
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962398/
  41. Mar 2025
  42. www.sciencedirect.com www.sciencedirect.com
    Single-cell transcriptomic and functional studies identify glial state changes and a role for inflammatory RIPK1 signaling in ALS pathogenesis
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    Phase I Trial of TTI-101, a First-in-Class Oral Inhibitor of STAT3, in Patients with Advanced Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11911802/
  45. Feb 2025
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic imaging distinguishes ovarian cancer subtypes and detects their early and variable responses to treatment
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  47. www.sciencedirect.com www.sciencedirect.com
    Targeting insulin-like growth factor 1 receptor restricts development and severity of secondary lymphedema in mice
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  48. aacrjournals.org aacrjournals.org
    Platinum-based chemotherapy induces opposing effects on immunotherapy response-related spatial and stromal biomarkers in the bladder cancer microenvironment
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    aacrjournals.org/clincancerres/article/30/18/4227/747456/Platinum-Based-Chemotherapy-Induces-Opposing
  49. Jan 2025
  50. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Activation of δ-opioid receptors blocks allodynia in a model of headache induced by PACAP
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17424
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  52. Dec 2024
  53. www.cell.com www.cell.com
    Cell therapy with human IL-10-producing ILC2s limits xenogeneic graft-versus-host disease by inhibiting pathogenic T cell responses
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    cell.com/cell-reports/fulltext/S2211-1247(24)01453-0
  54. Oct 2024
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Redirecting B7-H3.CAR T cells to Chemokines Expressed in Osteosarcoma Enhances Homing and Antitumor Activity in Preclinical Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443211/
  56. Sep 2024
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiplexed Spatial Profiling of Hodgkin Reed–Sternberg Cell Neighborhoods in Classic Hodgkin Lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369618/
  58. Aug 2024
  59. www.sciencedirect.com www.sciencedirect.com
    Multiplex Spatial Omics Reveals Changes in Immune-Epithelial Crosstalk During Inflammation and Dysplasia Development in Chronic IBD Patients
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    sciencedirect.com/science/article/pii/S2589004224017759
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    Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines
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    sciencedirect.com/science/article/pii/S2211124724009665
  61. journals.lww.com journals.lww.com
    Generation and Characterization of Ex Vivo Expanded... : Journal of Immunotherapy
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  62. www.cell.com www.cell.com
    Single-cell spatial multiomics reveals tumor microenvironment vulnerabilities in cancer resistance to immunotherapy
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    cell.com/cell-reports/fulltext/S2211-1247(24)00720-4
  63. Jul 2024
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adult-onset deletion of ATP13A2 in mice induces progressive nigrostriatal pathway dopaminergic degeneration and lysosomal abnormalities
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    ncbi.nlm.nih.gov/pmc/articles/PMC11271504/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake
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    ncbi.nlm.nih.gov/pmc/articles/PMC11219039/
  66. May 2024
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094425/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined CDK4/6 and ERK1/2 inhibition enhances anti-tumor activity in NF1-associated plexiform neurofibroma
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  69. Apr 2024
  70. www.sciencedirect.com www.sciencedirect.com
    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
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  71. Mar 2024
  72. www.thelancet.com www.thelancet.com
    Female mice display sex-specific differences in cerebrovascular function and subarachnoid haemorrhage-induced injury
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00093-8/abstract
  73. Feb 2024
  74. 52.53.155.43 52.53.155.43
    Imaging Glioblastoma Response to Radiotherapy Using 2H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism.
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  75. aacrjournals.org aacrjournals.org
    Imaging glioblastoma response to radiotherapy using 2H magnetic resonance spectroscopy measurements of fumarate metabolism
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    aacrjournals.org/cancerres/article/82/19/3622/709416/Imaging-Glioblastoma-Response-to-Radiotherapy
  76. Jan 2024
  77. www.sciencedirect.com www.sciencedirect.com
    Ventral pallidum neurons projecting to the ventral tegmental area reinforce but do not invigorate reward-seeking behavior
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  78. Dec 2023
  79. www.sciencedirect.com www.sciencedirect.com
    A cluster of neuropeptide S neurons regulates breathing and arousal
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  80. Nov 2023
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    The bone transcription factor Osterix controls extracellular matrix- and node of Ranvier-related gene expression in oligodendrocytes
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  82. Oct 2023
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    IL-1R1 signaling in TBI: assessing chronic impacts and neuroinflammatory dynamics in a mouse model of mild closed-head injury
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    link.springer.com/article/10.1186/s12974-023-02934-3
  84. Aug 2023
  85. dx.doi.org dx.doi.org
    Circulating and intratumoral immune determinants of response to atezolizumab plus bevacizumab in patients with variant histology or sarcomatoid renal cell carcinoma
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    dx.doi.org/10.1158/2326-6066.CIR-22-0996
  86. Jun 2023
  87. www.nature.com www.nature.com
    Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
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  88. May 2023
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  90. Apr 2023
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    CX3CR1 deficiency-induced TIL tumor restriction as a novel addition for CAR-T design in solid malignancies
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Liposome-Encapsulated Eribulin Shows Enhanced Antitumor Activity over Eribulin for Combination Therapy with Anti–PD-1 Antibody
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    ncbi.nlm.nih.gov/pmc/articles/PMC10068443/
  93. Mar 2023
  94. www.sciencedirect.com www.sciencedirect.com
    Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer
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  95. Oct 2022
  96. aacrjournals.org aacrjournals.org
    Imaging glioblastoma response to radiotherapy using 2H magnetic resonance spectroscopy measurements of fumarate metabolism
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    aacrjournals.org/cancerres/article/82/19/3622/709416/Imaging-Glioblastoma-Response-to-Radiotherapy
  97. Sep 2022
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biological misinterpretation of transcriptional signatures in tumor samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data
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    ncbi.nlm.nih.gov/pmc/articles/PMC9475248/
  99. www.sciencedirect.com www.sciencedirect.com
    Metronomic cyclophosphamide is more effective than a single dose in resistant tumours Cyclophosphamide depletes tumour infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma
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  100. Jul 2022
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    Sensory neurons display cell-type-specific vulnerability to loss of neuron-glia interactions
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC9056178/
  103. Jun 2022
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive surfaceome profiling to identify and validate novel cell-surface targets in osteosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9167717/
  105. May 2022
  106. aacrjournals.org aacrjournals.org
    Single cell characterization of the cellular landscape of acral melanoma identifies novel targets for immunotherapy
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    aacrjournals.org/clincancerres/article/28/10/2131/694823/Single-cell-Characterization-of-the-Cellular
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intra-Tumoral CD8+ T-Cell Infiltration and PD-L1 Positivity in Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9082359/
  108. Dec 2021
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8633968/
  110. Nov 2021
  111. elifesciences.org elifesciences.org
    Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion
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    elifesciences.org/articles/66721
  112. www.sciencedirect.com www.sciencedirect.com
    Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells
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  113. Oct 2021
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    Transcriptional and functional divergence in lateral hypothalamic glutamate neurons projecting to the lateral habenula and ventral tegmental area
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    sciencedirect.com/science/article/pii/S0896627321006930
  115. Sep 2021
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of T-cell Exhaustion Molecules and Human Endogenous Retroviruses as Predictive Biomarkers for response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC8443005/
  117. May 2021
  118. www.sciencedirect.com www.sciencedirect.com
    RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
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    sciencedirect.com/science/article/pii/S2211124721004460
  119. Jan 2021
  120. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Monomeric/dimeric forms of Fgf15/FGF19 show differential activity in hepatocyte proliferation and metabolic function
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202002203R
  121. Dec 2020
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques
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