82 Matching Annotations
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    Trilaciclib triggers a neutrophil-related immune response and sensitizes non-small cell lung cancer to anti-PD-1 therapy
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  3. Sep 2025
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    Cell-type-specific dysregulation of gene expression due to Chd8 haploinsufficiency during mouse cortical development
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    Single-cell analysis of Barrett’s esophagus and carcinoma reveals cell types conferring risk via genetic predisposition
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    Plasma exosomes from individuals with type 2 diabetes drive breast cancer aggression in patient-derived organoids
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    RACK1 attenuates pancreatic tumorigenesis by suppressing acinar-to-ductal metaplasia through inflammatory signaling modulation
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  8. Aug 2025
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    Characteristics of a CCL21 gene-modified dendritic cell vaccine utilized for a clinical trial in non-small cell lung cancer
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  10. Jul 2025
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    A developmental program of early residency promotes the differentiation of divergent uterine NK cell subsets in humans
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    Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity
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    An organ-chip model of sporadic ALS using iPSC-derived spinal cord motor neurons and an integrated blood-brain-like barrier
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    Single-Cell Transcriptomic Landscape Deciphers Intratumoral Heterogeneity and Subtypes of Acral and Mucosal Melanomas
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  16. May 2025
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    Microglia aging in the hippocampus advances through intermediate states that drive activation and cognitive decline
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    Multimodal analyses reveal genes driving electrophysiological maturation of neurons in the primate prefrontal cortex
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    Diversity and functional specialization of oyster immune cells uncovered by integrative single-cell level investigations
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    The 9p21.3 Coronary Artery Disease Risk Locus Drives Vascular Smooth Muscle Cells to an Osteochondrogenic State
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    Single-cell transcriptomic profiling reveals diversity in human iNKT cells across hematologic tissues
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  22. Apr 2025
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    Determinants of Response to Sequential Pembrolizumab with Trastuzumab plus Platinum/5-FU in HER2-Positive Gastric Cancer: A Phase II Chemoimmunotherapy Trial
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    Protocol for characterizing craniopharyngioma subtypes and their microenvironments using single-cell RNA sequencing and immunohistochemistry
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    MIRO1 mutation leads to metabolic maladaptation resulting in Parkinson’s disease-associated dopaminergic neuron loss
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    snRNA-seq analysis of the moss Physcomitrium patens reveals a conserved cytokinin-ESR module promoting pluripotent stem cell identity
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    Islet single-cell transcriptomic profiling during obesity-induced beta cell expansion in female mice
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    snRNA-seq analysis of the moss Physcomitrium patens identifies a conserved cytokinin-ESR module promoting pluripotent stem cell identity
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  31. Feb 2025
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    Copper Drives Remodeling of Metabolic State and Progression of Clear Cell Renal Cell Carcinoma
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    Phenotypic plasticity and increased infiltration of peripheral blood-derived TREM1+ mono-macrophages following radiotherapy in rectal cancer
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  36. Dec 2024
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  39. Nov 2024
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    Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma
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  41. Jul 2024
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    Single-cell RNA Sequencing Identifies a Novel Subtype of Microglia with High Cd74 Expression that Facilitates White Matter Inflammation During Chronic Cerebral Hypoperfusion
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  45. Jun 2024
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  47. May 2024
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    An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination
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    PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma
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  51. Feb 2024
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    Comparative transcriptomic analysis of bovine mesenchymal stromal cells reveals tissue-source and species-specific differences
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  53. Jan 2024
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    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
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  55. Dec 2023
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    scNAT: a deep learning method for integrating paired single-cell RNA and T cell receptor sequencing profiles
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    Multipotent progenitors instruct ontogeny of the superior colliculus
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    A single-cell multi-omic atlas spanning the adult rhesus macaque brain
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  59. Oct 2023
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  61. Sep 2023
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    Single-cell multi-omics defines the cell-type-specific impact of splicing aberrations in human hematopoietic clonal outgrowths
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    Spatially Distinct Otic Mesenchyme Cells show Molecular and Functional Heterogeneity Patterns Before Hearing Onset
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    Activin A-mediated polarization of cancer-associated fibroblasts and macrophages confers resistance to checkpoint immunotherapy in skin cancer
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  65. Aug 2023
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    Homeostatic PD-1 signaling restrains EOMES-dependent oligoclonal expansion of liver-resident CD8 T cells
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    Comparative single-cell profiling reveals distinct cardiac resident macrophages essential for zebrafish heart regeneration
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    Sex shapes cell-type-specific transcriptional signatures of stress exposure in the mouse hypothalamus
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  69. Jul 2023
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    Single-cell RNA-seq uncovers novel metabolic functions of Schwann cells beyond myelination
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    Endothelial and Leptin Receptor+ cells promote the maintenance of stem cells and hematopoiesis in early postnatal murine bone marrow
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    Lineage skewing and genome instability underlie marrow failure in a zebrafish model of GATA2 deficiency
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  77. May 2023
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    Integrative transcriptomics and cell systems analyses reveal protective pathways controlled by Igfbp-3 in anthracycline-induced cardiotoxicity
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    Metaphocytes are IL-22BP-producing cells regulated by ETS transcription factor Spic and essential for zebrafish barrier immunity
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    Bovine blastocyst-like structures derived from stem cell cultures
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  81. Apr 2023
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    Glucocerebrosidase is imported into mitochondria and preserves complex I integrity and energy metabolism
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  83. Mar 2023
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    Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1
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    Proliferative exhausted CD8+ T cells exacerbate long-lasting anti-tumor effects in human papillomavirus-positive head and neck squamous cell carcinoma
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  86. Dec 2022
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    Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness Versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis
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  88. Nov 2022
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    De-erosion of X chromosome dosage compensation by the editing of XIST regulatory regions restores the differentiation potential in hPSCs
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    CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation
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    Derivation of nociceptive sensory neurons from hiPSCs with early patterning and temporally controlled NEUROG2 overexpression
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  92. Oct 2022
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    Elevated pentose phosphate pathway flux supports appendage regeneration
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  94. Sep 2022
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    STAG2 promotes the myelination transcriptional program in oligodendrocytes
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  96. Aug 2022
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    Identification of a drug-response gene in multiple myeloma through longitudinal single-cell transcriptome sequencing
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    Single-cell and spatial mapping Identify cell types and signaling Networks in the human ureter
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  99. May 2022
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    Integrative analysis of scRNA-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator
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  101. Mar 2022
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    Novel insights from a multiomics dissection of the Hayflick limit
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    Hypertrophic chondrocytes serve as a reservoir for marrow-associated skeletal stem and progenitor cells, osteoblasts, and adipocytes during skeletal development
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    Cholesterol biosynthesis defines oligodendrocyte precursor heterogeneity between brain and spinal cord
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  105. Sep 2021
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    Loss of Mir146b with aging contributes to inflammation and mitochondrial dysfunction in thioglycollate-elicited peritoneal macrophages
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  107. Aug 2021
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    Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair
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  109. Jun 2021
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    Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states
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  111. May 2021
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    A phenotypically supervised single-cell analysis protocol to study within-cell-type heterogeneity of cultured mammalian cells
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    Dynamic profiles and transcriptional preferences of histone modifications during spermiogenesis
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  114. Apr 2021
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    Cascade diversification directs generation of neuronal diversity in the hypothalamus
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  116. Mar 2021
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    Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery
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  118. Jan 2021
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    Runx2-Twist1 interaction coordinates cranial neural crest guidance of soft palate myogenesis
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  120. Dec 2020
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    Excessive E2F Transcription in Single Cancer Cells Precludes Transient Cell-Cycle Exit after DNA Damage
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  122. Oct 2020
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    Lysosomal protein surface expression discriminates fat- from bone-forming human mesenchymal precursor cells
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