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    p53 activates chaperone-mediated autophagy to remodel metabolism and suppress tumorigenesis
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    sciencedirect.com/science/article/pii/S1534580726003953
  3. Aug 2026
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    The CNNM-binding interface drives PRL-3-dependent tumor progression in de novo cancer models
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    sciencedirect.com/science/article/pii/S2589004226027161
  5. Jul 2026
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    A self-amplifying nerve-fibroblast circuit drives colorectal cancer progression
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    sciencedirect.com/science/article/pii/S1535610826003053
  7. aacrjournals.org aacrjournals.org
    Stress-Induced ADGRL4 Orchestrates Tumor Progression and Metastasis by Inhibiting YAP1 Signaling and Activating Angiogenesis
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    aacrjournals.org/cancerres/article/86/11/2743/785311/Stress-Induced-ADGRL4-Orchestrates-Tumor
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    Mineralocorticoid and glucocorticoid receptor cooperation drives advanced phenotypes in triple-negative breast cancer
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    dx.doi.org/10.1210/endocr/bqag055
  9. May 2026
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    The proteomics and phosphoproteomics landscape of melanoma under T cell attack
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    sciencedirect.com/science/article/pii/S2666379126002466
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    Tissue tension fosters macrophage-driven lipid peroxidation-induced DNA damage
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    sciencedirect.com/science/article/pii/S1535610826001765
  12. Apr 2026
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    RASSF2 promoter hypermethylation determines malignant and microenvironmental features in lung cancer
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    nature.com/articles/s41435-026-00398-y
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An antibody-drug conjugate designed through clone and isotype selection restricts the growth of CSPG4-expressing triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13096323/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RHOV is a Detachment-Responsive Rho GTPase Necessary for Ovarian Cancer Peritoneal Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13089303/
  16. onlinelibrary.wiley.com onlinelibrary.wiley.com
    CCL26-Mediated Modulation of Endothelial Secretome by Hypoxia-Induced Tumor-Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer
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    onlinelibrary.wiley.com/doi/full/10.1002/hed.70259
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated bulk RNA-seq and scRNA-seq identification of a novel “PET-SPI1-MYL9” transcriptional axis in lung adenocarcinoma driven by polyethylene terephthalate exposure
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    pmc.ncbi.nlm.nih.gov/articles/PMC13067007/
  18. Feb 2026
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modulating the tumor immune phenotypes by radiotherapy: formulating and validating the combination therapy of radiation, PD-L1, and TIM-3 blockade in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12933762/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EHF as a key regulator mediating cell migration and may contribute to tumor immune infiltration and progression in human endometrial cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12882267/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cyclic di-GMP suppresses cancer metastasis by targeting proteasome 26S subunit non-ATPase 3 independently of STING
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    pmc.ncbi.nlm.nih.gov/articles/PMC12868630/
  22. Jan 2026
  23. www.nature.com www.nature.com
    RAS/MEK/PI3K pathway inhibition augments response to CD40 agonism by targeting CD11b+ Bregs thereby overcoming melanoma PD1-resistance
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    nature.com/articles/s41467-025-67315-1
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    SIRT2 Mitigates Radiation-Induced Oral Mucositis by Promoting Homologous Recombination-Mediated DNA Double-Strand Break Repair in Epithelial Stem Cells
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    sciencedirect.com/science/article/pii/S0304383526000029
  25. Dec 2025
  26. www.nature.com www.nature.com
    KRT81 promotes metastasis of colorectal cancer by acting as a protein scaffold for ezrin
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    nature.com/articles/s41388-025-03665-w
  27. Nov 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neutrophil Dynamics Contribute to Disease Progression and Poor Survival in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12607450/
  29. Oct 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bone-Induced Her2 Promotes Secondary Metastasis in HR+/Her2− Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964846/
  31. Sep 2025
  32. www.sciencedirect.com www.sciencedirect.com
    Anticancer effects of 6-diazo-5-oxo-L-norleucine (DON)-loaded PLGA nanoparticles in triple-negative breast cancer by inhibiting glutamine metabolism: An integrated bioinformatic and experimental approach
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    sciencedirect.com/science/article/pii/S1773224725009025
  33. Aug 2025
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A comparison of hepatitis B virus- and hepatitis C virus-related hepatocellular carcinoma: a bioinformatics analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12335692/
  35. Jun 2025
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphatase activity is dispensable for PRL-3-mediated oncogenesis and tumor progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12132575/
  37. May 2025
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Disruption of P2Y2 Signaling Promotes Breast Tumor Cell Dissemination by Reducing ATP-Dependent Calcium Elevation and Actin Localization to Cell Junctions
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    pmc.ncbi.nlm.nih.gov/articles/PMC12071985/
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    Magnolol facilitates mitochondrial-peroxisome dysfunction and induces oxeiptosis in lung cancer cells following transfer via tunneling nanotubes
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    sciencedirect.com/science/article/pii/S0753332225003208
  40. Apr 2025
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12009992/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lineage Tracing and Single-Cell RNA Sequencing Reveal a Common Transcriptional State in Breast Cancer Tumor–Initiating Cells Characterized by IFN/STAT1 Activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11997551/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    VAX014 Activates Tumor-Intrinsic STING and RIG-I to Promote the Development of Antitumor Immunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962400/
  44. Mar 2025
  45. www.sciencedirect.com www.sciencedirect.com
    GEF-H1 drives breast cancer cells to tumor progression
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    sciencedirect.com/science/article/pii/S0925443925001619
  46. academic.oup.com academic.oup.com
    Homeodomain protein PRRX1 anchors the Ku heterodimers at DNA double-strand breaks to promote nonhomologous end-joining
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    academic.oup.com/nar/article/53/6/gkaf200/8089753
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Induction of Triple-Negative Breast Cancer Cell Death and Chemosensitivity Using mTORC2-Directed RNAi Nanomedicine
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    pmc.ncbi.nlm.nih.gov/articles/PMC11921867/
  48. Feb 2025
  49. aacrjournals.org aacrjournals.org
    HnRNPAB promotes pancreatic ductal adenocarcinoma extravasation and liver metastasis by stablizing MYC mRNA
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    aacrjournals.org/mcr/article/22/11/1022/749159/hnRNPAB-Promotes-Pancreatic-Ductal-Adenocarcinoma
  50. Mar 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MARCH2, a novel oncogene-regulated SNAIL E3 ligase, suppresses triple negative breast cancer metastases
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    ncbi.nlm.nih.gov/pmc/articles/PMC10977041/
  52. Feb 2024
  53. www.sciencedirect.com www.sciencedirect.com
    Cdc42-driven endosomal cholesterol transport promotes collateral resistance in HER2-positive gastric cancer
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    sciencedirect.com/science/article/pii/S0304383524000958
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant Upregulation of RUNX3 Activates Developmental Genes to Drive Metastasis in Gastric Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10836196/
  55. Jan 2024
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in Lung Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10790128/
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Therapeutic antibody targeting natriuretic peptide receptor 1 inhibits gastric cancer growth via BCL-2-mediated intrinsic apoptosis
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.34831
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    Genetic insights into carbohydrate sulfotransferase 8 and its impact on the immunotherapy efficacy of cancer
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    sciencedirect.com/science/article/pii/S2211124723016522
  59. Sep 2023
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    YAP/TEAD-induced PRIM1 contributes to the progression and poor prognosis of gastric carcinoma
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    sciencedirect.com/science/article/pii/S1936523323001778
  61. Jul 2023
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of VPS13C promotes cisplatin resistance in cervical cancer by upregulating GSTP1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10372835/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The combination of NDUFS1 with CD4+ T cell infiltration predicts favorable prognosis in kidney renal clear cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10352660/
  64. Apr 2023
  65. www.biorxiv.org www.biorxiv.org
    Metastatic breast cancer cells have reduced calcium and actin response after ATP-P2Y2 signaling
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    biorxiv.org/content/10.1101/2023.03.31.533191v1
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10069867/
  67. Mar 2023
  68. link.springer.com link.springer.com
    VE-822 upregulates the deubiquitinase OTUD1 to stabilize FHL1 to inhibit the progression of lung adenocarcinoma
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    link.springer.com/article/10.1007/s13402-023-00793-x
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    S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) inhibits lung cancer tumorigenesis by regulating cell plasticity
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    link.springer.com/article/10.1186/s13062-023-00364-y
  70. Jan 2023
  71. aacrjournals.org aacrjournals.org
    Spatial transcriptomic analysis of a diverse patient cohort reveals a conserved architecture in triple-negative breast cancer
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    aacrjournals.org/cancerres/article/83/1/34/711842/Spatial-Transcriptomic-Analysis-of-a-Diverse
  72. Dec 2022
  73. aacrjournals.org aacrjournals.org
    TFAP4 activates IGF2BP1 and promotes progression of non-small cell lung cancer by stabilizing TK1 expression through m6A modification
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    aacrjournals.org/mcr/article/20/12/1763/711001/TFAP4-Activates-IGF2BP1-and-Promotes-Progression
  74. Nov 2022
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genomic and transcriptomic study toward breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9596791/
  76. Sep 2022
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    E2F1 as a potential prognostic and therapeutic biomarker by affecting tumor development and immune microenvironment in hepatocellular carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9459514/
  78. Nov 2021
  79. elifesciences.org elifesciences.org
    Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion
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    elifesciences.org/articles/66721
  80. Oct 2021
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PDLIM5 inhibits STUB1-mediated degradation of SMAD3 and promotes the migration and invasion of lung cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC7535919/
  82. Aug 2021
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Helicobacter pylori infection downregulates the DNA glycosylase NEIL2, resulting in increased genome damage and inflammation in gastric epithelial cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC7415988/
  84. May 2021
  85. www.sciencedirect.com www.sciencedirect.com
    LDLR inhibition promotes hepatocellular carcinoma proliferation and metastasis by elevating intracellular cholesterol synthesis through MEK/ERK signaling pathway
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    sciencedirect.com/science/article/pii/S2212877821000752
  86. Apr 2021
  87. www.sciencedirect.com www.sciencedirect.com
    Dual blockade of EGFR and CDK4/6 delays head and neck squamous cell carcinoma progression by inducing metabolic rewiring
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    sciencedirect.com/science/article/pii/S0304383521001580
  88. Mar 2021
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The expression patterns and prognostic significance of pleckstrin homology-like domain family A (PHLDA) in lung cancer and malignant mesothelioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC7947487/
  90. Dec 2020
  91. www.frontiersin.org www.frontiersin.org
    Lysine in Combination With Estradiol Promote Dissemination of Estrogen Receptor Positive Breast Cancer via Upregulation of U2AF1 and RPN2 Proteins
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    frontiersin.org/article/10.3389/fonc.2020.598684/full