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    A high-resolution atlas of the brain predicts lineage and birth order underlying neuronal identity
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  3. Dec 2025
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    Digital twins for in vivo metabolic flux estimations in patients with brain cancer
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    A Multipotent PROX1+ Tumor Stem/Progenitor Cell Population Emerges during Intestinal Tumorigenesis and Mediates Radioresistance in Colorectal Cancer
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    C9orf72 Repeat Expansion Induces Metabolic Dysfunction in Human iPSC‐Derived Microglia and Modulates Glial‐Neuronal Crosstalk
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  7. Nov 2025
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    Deep profiling of human T cells defines compartmentalized clones and phenotypic trajectories across blood and tonsils
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    Identification of immunogenic KIF5B-RET fusion neopeptides driving immune stimulation in tumor specific CD8+ T cells
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    Hypertension-induced neurovascular and cognitive dysfunction at single-cell resolution
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    Circulating neoantigen- and viral oncoprotein–specific CD8+ T cells share a transcriptional signature
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    Trilaciclib triggers a neutrophil-related immune response and sensitizes non-small cell lung cancer to anti-PD-1 therapy
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  13. Sep 2025
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    PIN1 prolyl isomerase promotes initiation and progression of bladder cancer through the SREBP2-mediated cholesterol biosynthesis pathway
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    A phase I clinical trial adding OX40 agonism to in situ therapeutic cancer vaccination in patients with low-grade B cell lymphoma highlights challenges in translation from mouse to human studies
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    Plasma exosomes from individuals with type 2 diabetes drive breast cancer aggression in patient-derived organoids
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  17. Aug 2025
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    Preservation and Clonal Behavior of Extrachromosomal DNA in Patient-Derived Xenograft Models of Childhood Cancers
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    Lipid nanoparticles as a tool to dissect dendritic cell maturation pathways
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  20. Jul 2025
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    Imeglimin suppresses glucagon secretion and induces a loss of α cell identity
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    G-protein-coupled receptor ADGRG1 drives a protective microglial state in Alzheimer's disease through MYC activation
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    Cognate interaction-dependent pathogenicity of meningeal B cells drives neuroinflammation relapse
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    Dissecting FAP+ Cell Diversity in Pancreatic Cancer Uncovers an Interferon-Response Subtype of Cancer-Associated Fibroblasts with Tumor-Restraining Properties
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  26. Jun 2025
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    Temporal evolution of fibroblast responses following salivary gland ductal ligation injury
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    Single-Cell Transcriptomic Landscape Deciphers Intratumoral Heterogeneity and Subtypes of Acral and Mucosal Melanomas
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  32. May 2025
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    Multimodal analyses reveal genes driving electrophysiological maturation of neurons in the primate prefrontal cortex
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    Epigenetic silencing of DNA sensing pathway by FOXM1 blocks stress ligand-dependent antitumor immunity and immune memory
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    Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target
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  37. Apr 2025
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  39. Mar 2025
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    Lineage contribution of the mesendoderm progenitors in the gastrulating mouse embryo
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  41. Feb 2025
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    Methionine intervention induces PD-L1 expression to enhance the immune checkpoint therapy response in MTAP-deleted osteosarcoma
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  44. Jan 2025
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    Single-Cell RNA Sequencing before and after Light Chain Escape Reveals Intrapatient Multiple Myeloma Subpopulations with Divergent Osteolytic Gene Expression
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  48. Dec 2024
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    Expanding GABAergic Neuronal Diversity in iPSC-Derived Disease Models
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    Early downmodulation of tumor glycolysis predicts response to fasting-mimicking diet in triple-negative breast cancer patients
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  51. Nov 2024
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    NF-ΚB Activation as a Key Driver in Chronic Lymphocytic Leukemia Evolution to Richter’s Syndrome: Unraveling the Influence of Immune Microenvironment Dynamics
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  53. Oct 2024
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  55. Sep 2024
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    Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
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    Reconstitution of the Multiple Myeloma Microenvironment Following Lymphodepletion with BCMA CAR-T Therapy
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  58. Aug 2024
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  60. Jul 2024
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    Single-cell RNA Sequencing Identifies a Novel Subtype of Microglia with High Cd74 Expression that Facilitates White Matter Inflammation During Chronic Cerebral Hypoperfusion
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  63. May 2024
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    Psilocybin Promotes Cell-Type-Specific Changes in the Orbitofrontal Cortex Revealed by Single-Nucleus RNA-seq
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  66. Apr 2024
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    Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization
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  68. Mar 2024
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    Deciphering the spatiotemporal transcriptional and chromatin accessibility of human retinal organoid development at the single-cell level
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    A novel type of monocytic leukemia stem cell revealed by the clinical use of venetoclax-based therapy
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  71. Feb 2024
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    Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
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  73. Jan 2024
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    Establishing a 3D culture system for early organogenesis of monkey embryos ex vivo and single-cell transcriptome analysis of cultured embryos
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    FOXP1 regulates the development of excitatory synaptic inputs onto striatal neurons and induces phenotypic reversal with reinstatement
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  77. Dec 2023
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    Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection.
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  79. Nov 2023
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    Cancer-prone Phenotypes and Gene Expression Heterogeneity at Single-cell Resolution in Cigarette-smoking Lungs
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  81. Oct 2023
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    Single-cell transcriptomics illuminates regulatory steps driving anterior-posterior patterning of Drosophila embryonic mesoderm
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  83. Jul 2023
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    A single-cell atlas of the sexually dimorphic Drosophila foreleg and its sensory organs during development
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  85. Jun 2023
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    Organized B cell sites in cartilaginous fishes reveal the evolutionary foundation of germinal centers
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  87. Apr 2023
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    Brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke
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  90. Mar 2023
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    Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1
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  92. Feb 2023
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    Runx1 controls auditory sensory neuron diversity in mice
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  94. Dec 2022
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deciphering Transcriptional Networks during Human Cardiac Development
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  96. Aug 2022
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    Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors
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    Gliotransmission of D-serine promotes thirst-directed behaviors in Drosophila
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  99. Jun 2022
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    Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice
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  101. Mar 2022
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain
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  103. Feb 2022
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    Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target
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  105. Jun 2021
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    Single-cell transcriptomics defines heterogeneity of epicardial cells and fibroblasts within the infarcted murine heart
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  107. May 2021
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    A single-cell analysis of the Arabidopsis vegetative shoot apex
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  109. Feb 2021
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    RUNX1 marks a luminal castration-resistant lineage established at the onset of prostate development
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  111. Jan 2021
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    Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing
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  113. Dec 2020
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes
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