142 Matching Annotations
  1. Last 7 days
  2. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Running-based rehabilitation does not improve muscle function after volumetric muscle loss despite improving hindlimb weight-bearing asymmetry in mice
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    physoc.onlinelibrary.wiley.com/doi/10.1113/EP094201
  3. onlinelibrary.wiley.com onlinelibrary.wiley.com
    <fc>AMPK</fc> Activator <fc>MK</fc>‐8722 Improves Spatial Memory Deficit and Alters Metabolome in <fc>APP</fc>/<fc>PS1 AD</fc> Mouse Model
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.70563
  4. Sep 2026
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    Directing GABAergic neuronal identity from human iPSCs through developmental patterning
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    sciencedirect.com/science/article/pii/S2213671126002973
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    Dysregulation of Hippocampal Autophagic Machinery in the Activity-Based Anorexia Rat Model
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70549
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    1-s2.0-S0531556526002822-main-html.html
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    54.241.53.176/4098b89ef2e7286504ea1b0e62210509f3424272/1-s2.0-S0531556526002822-main-html.html
  8. Aug 2026
  9. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Hippocampal Astrocytes Impact Postnatal Development of Inhibitory Connections, Parvalbumin Levels, Social, and Spatial Navigation Behaviors in a Mouse Model of Fragile X Syndrome
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70541
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular Mechanisms Underlying FCCP-Induced Mitophagy in Human Airway Smooth Muscle Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13487762/
  11. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deciphering the Molecular Basis: Integrative Multi‐Method Analysis of Bioactive Constituents and Their Anti‐Lung Cancer Mechanisms in Clinical Traditional Chinese Medicine Formulations
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71606
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HER2 heterogeneous breast cancer models reveal novel therapeutic targets and subclonal dynamics during evolution to resistance to HER2-targeted therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC13430225/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the NAD+ salvage pathway blocks metabolic recovery and enhances β-lapachone toxicity in NQO1-expressing glioblastoma cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13430001/
  14. Jul 2026
  15. 54.241.53.176 54.241.53.176
    mahadev-bhat-et-al-2026-molecular-mechanisms-underlying-fccp-induced-mitophagyin-human-airway-smooth-muscle-cells-html.html
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    Epithelial-mesenchymal transition is associated with altered immune composition and cytotoxic function in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13374390/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KRAS-mediated CCDC6 degradation drives xCT upregulation and ferroptosis evasion
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    pmc.ncbi.nlm.nih.gov/articles/PMC13369686/
  18. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Genetic Deletion of Adenosine <fc>A<sub>2A</sub></fc> Receptors Attenuates Aged‐Related Alterations of Glial Cells Morphology and of Inflammasome in the Hippocampus and Prefrontal Cortex of Mice
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    onlinelibrary.wiley.com/doi/10.1002/glia.70197
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    Paternal exposure to chlorpyrifos disrupts protein regulation and abolishes PKCβ signaling in learning‑related neural circuits
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    sciencedirect.com/science/article/pii/S0161813X26001270
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss
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    pmc.ncbi.nlm.nih.gov/articles/PMC13318054/
  21. Jun 2026
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Circulating sphingosine-1-phosphate depletion is associated with endothelial activation and altered brain-endothelial S1P pathway expression in ischemic stroke
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    pmc.ncbi.nlm.nih.gov/articles/PMC13285081/
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    WEE1 kinase inhibition to overcome acquired resistance to targeted therapies in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13269805/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeted KRASG12V Degradation in vivo Elicits Lung Adenocarcinoma Regression with Subsequent Relapse from Dysregulated Proteolysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC7619155/
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    The HDAC Inhibitor RM-3-22 Suppresses Triple-Negative Breast Cancer by Uncoupling Autophagy to Drive FSP1-Dependent Ferroptosis
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    sciencedirect.com/science/article/pii/S1931524426001210
  26. May 2026
  27. www.biorxiv.org www.biorxiv.org
    YY1 Binding Motif at Upstream of Rep/Cap Increases AAV Yield and Full Capsids
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    biorxiv.org/content/10.64898/2026.05.21.726733v1
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    Autophagy-lysosomal dependency defines a vulnerable physiological state in drug-tolerant persister cells of triple-negative breast cancer
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    link.springer.com/article/10.1007/s10495-026-02310-5
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dietary Fat Content Influences PanIN Progression and Pancreatic Cancer Development in Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC13139957/
  30. Apr 2026
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Myofibroblasts induce neuroplasticity to promote pancreatic inflammation and cancer progression
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    P21-positive senescent stromal cells promote prostate cancer immune suppression and progression that can be reversed by senolytic therapy
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    aacrjournals.org/cancerdiscovery/article/16/3/571/774737/p21-Positive-Senescent-Stromal-Cells-Promote
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    Inherent Lipid Composition Abnormalities in Astrocytes Associated with Late-Onset Alzheimer’s Disease (LOAD)
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    mdpi.com/2073-4409/15/6/549
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    CCL26-Mediated Modulation of Endothelial Secretome by Hypoxia-Induced Tumor-Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer
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    onlinelibrary.wiley.com/doi/full/10.1002/hed.70259
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutational Signatures and Clonal Hematopoiesis in Intestinal Metaplasia across Countries with Varying Stomach Cancer Incidence
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    pmc.ncbi.nlm.nih.gov/articles/PMC13056296/
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    Inflammaging-associated mitochondrial degeneration occurs in hypoglossal motor neurons prior to tongue muscle
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    link.springer.com/article/10.1007/s11357-026-02226-7
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    Genetic deletion of adenosine A2A receptors attenuates memory deterioration and alterations of synaptic plasticity and metabolic controllers in the hippocampus and prefrontal cortex of aged mice
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    link.springer.com/article/10.1007/s11357-026-02219-6
  39. Mar 2026
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    Chemoradiation Reprograms Tumor Cells and the Immune Microenvironment in Cervical Cancer
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    Medium-Chain Fatty Acid Receptor GPR84 Modulates Cytotoxic CD8 T cells Antitumor Immunity Through Metabolic Reprogramming
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    CF10 Displays Improved Synergy with Oxaliplatin in TP53-Null and Wild-Type CRC Cells from Increased Top1cc and Replication Stress
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    Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy
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    Neuroprotection From Intracerebral Hemorrhage Following Pharmacological Inhibition of GSK3β Depends on HFE Gene Status
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    pmc.ncbi.nlm.nih.gov/articles/PMC12954159/
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    S6K1 Modulates STAT3 Activation to Promote Resistance to Radiotherapy in Lung Cancer
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    Targeting peptidyl-arginine deiminase 4 suppresses SARS-CoV-2 replication and modulates the inflammatory response
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  47. Feb 2026
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Unraveling Network Pharmacology‐Based Therapeutics of Anthranilate Sulfonamides via Sirtuins/FOXO3a Cascade in Alzheimer's Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12920268/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of CTLH component MAEA impairs DNA repair and replication and leads to developmental delay
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    pmc.ncbi.nlm.nih.gov/articles/PMC12905269/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    N‐Truncated Superoxide Dismutase‐1 in Cerebrospinal Fluid Is Folded and Active
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    Netrin-1 Promotes Pancreatic Tumorigenesis and Innervation through NEO1
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    Cyclic di-GMP suppresses cancer metastasis by targeting proteasome 26S subunit non-ATPase 3 independently of STING
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  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aberrant Hippo-YAP/TEAD Signaling Drives Malignant Transcriptional Reprogramming in External Auditory Canal Squamous Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12862246/
  54. Jan 2026
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Role of the ETV5/p38 signaling axis in aggressive thyroid cancer cells
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  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Wilm’s Tumor 1-Expressing Stromal Cells Promote Pancreatic Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12809115/
  57. 54.241.53.176 54.241.53.176
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  58. www.biorxiv.org www.biorxiv.org
    Reverse molecular pharmacology identifies the non-canonical axis of IRAK as a chemoresistance factor in neuroblastoma
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    biorxiv.org/content/10.64898/2026.01.09.697473v1
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    Candida albicans drives colorectal cancer progression by inducing hypoxia signaling
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    elifesciences.org/reviewed-preprints/108665
  60. Dec 2025
  61. www.sciencedirect.com www.sciencedirect.com
    Astrocytic GABA controls fidelity of temporal cortical processing in Fragile X Syndrome
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  62. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    TDP-43 dysfunction compromises UPF1-dependent mRNA metabolism in ALS
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  63. Nov 2025
  64. www.embopress.org www.embopress.org
    Inhibiting cholesterol synthesis halts rhabdomyosarcoma growth via ER stress and cell cycle arrest
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    embopress.org/doi/10.1038/s44321-025-00336-x
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Altered GABAergic Homeostasis in the Striatum of Dopamine Transporter Knockout Rats
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    pmc.ncbi.nlm.nih.gov/articles/PMC12613098/
  66. www.biorxiv.org www.biorxiv.org
    Acute AMPK activation does not adequately stimulate insulin signaling in skeletal muscle models of Myotonic Dystrophy Type 1
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    biorxiv.org/content/10.1101/2025.11.04.686135v1
  67. Oct 2025
  68. www.biorxiv.org www.biorxiv.org
    Epithelial-Mesenchymal Transition is Associated with Altered Immune Composition and Cytotoxic Function in Triple-Negative Breast Cancer
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    biorxiv.org/content/10.1101/2025.10.22.683714v1
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    Cryo-EM reveals how ASX-173 inhibits human asparagine synthetase to activate the integrated stress response
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    biorxiv.org/content/10.1101/2025.10.16.682859v2
  70. Sep 2025
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    ER stress tolerance is regulated by copper-dependent PERK kinase activity
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    High-throughput bioprinting to produce micropatterened neuroepithelial tissues and model TSC2-deficient brain malformations
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    Neurons sequester the cholesterol-inhibiting TFEB in oligodendrocyte cytoplasm to safeguard myelination and neural function
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  74. Aug 2025
  75. www.medrxiv.org www.medrxiv.org
    Specific Lipid Abnormalities Are Inherently Associated with Late-Onset Alzheimer’s Disease
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    medrxiv.org/content/10.1101/2025.08.08.25333304v1
  76. onlinelibrary.wiley.com onlinelibrary.wiley.com
    5-HT6 Receptor Inverse Agonists Modulate Diabetic Neuropathic Pain in Female Rats: Evidence for 5-HT6 Receptor Constitutive Activity
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    Methylphenidate triggers retinal oxidative stress and mitochondrial dysfunction under physiological conditions but has beneficial effects in inflammatory settings
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  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The CCL2-CCR2 axis drives neuromuscular denervation in amyotrophic lateral sclerosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12316999/
  80. Jul 2025
  81. www.oaepublish.com www.oaepublish.com
    CF10/LV overcomes acquired resistance to 5-FU/LV in colorectal cancer cells through downregulation of the c-Myc/ABCB5 axis
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    Ubiquitin chain variability directs substrates of the Tul1 ubiquitin ligase complex to different degradation pathways
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  83. Jun 2025
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    Gut dysbiosis from high-salt diet promotes glioma via propionate-mediated TGF-β activation
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    SOD1 Protein Content in Human Central Nervous System and Peripheral Tissues
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  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Store-operated Ca2+ entry is involved in endothelium-to-mesenchymal transition in lung vascular endothelial cells
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    In Vitro Anticancer Activity of Phytol on Human Non-Small Cell Lung Cancer A549 Cells
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    In Vitro Anticancer Activity of Phytol on Human Non-Small Cell Lung Cancer A549 Cells
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    journals.sagepub.com/doi/full/10.1177/15347354251344592
  90. May 2025
  91. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-resolution transcriptional impact of AIRE: effects of pathogenic variants p.Arg257Ter, p.Cys311Tyr, and polygenic risk variant p.Arg471Cys
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    pmc.ncbi.nlm.nih.gov/articles/PMC12053179/
  92. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Memory T‐Cell Phenotype in Cutaneous T‐Cell Lymphoma Is Modified by Germline Gene Gametocyte Specific Factor 1
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    Peroxisomes are critical for a unique metabolic demand and survival of alveolar macrophages
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  94. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modulation of GABAergic System in a Chicken Retinal Ischemic Model: The Role of Chloride Cotransporters
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    pmc.ncbi.nlm.nih.gov/articles/PMC12067523/
  95. Apr 2025
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    Impact of heterologous expression of Cannabis sativa tetraketide synthase on Phaeodactylum tricornutum metabolic profile
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    Both Proteins/Peptides and Non-Proteins/Peptides in Larval Oral Secretions of a Chewing Herbivore Function as Elicitors That Induce Plant Defenses
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  98. Mar 2025
  99. academic.oup.com academic.oup.com
    Homeodomain protein PRRX1 anchors the Ku heterodimers at DNA double-strand breaks to promote nonhomologous end-joining
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