136 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular Mechanisms Underlying FCCP-Induced Mitophagy in Human Airway Smooth Muscle Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13487762/
  3. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deciphering the Molecular Basis: Integrative Multi‐Method Analysis of Bioactive Constituents and Their Anti‐Lung Cancer Mechanisms in Clinical Traditional Chinese Medicine Formulations
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71606
  4. Aug 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HER2 heterogeneous breast cancer models reveal novel therapeutic targets and subclonal dynamics during evolution to resistance to HER2-targeted therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC13430225/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the NAD+ salvage pathway blocks metabolic recovery and enhances β-lapachone toxicity in NQO1-expressing glioblastoma cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13430001/
  7. Jul 2026
  8. 54.241.53.176 54.241.53.176
    mahadev-bhat-et-al-2026-molecular-mechanisms-underlying-fccp-induced-mitophagyin-human-airway-smooth-muscle-cells-html.html
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    54.241.53.176/de75a76d2d2b46ca55035530525641390ca5e88a/mahadev-bhat-et-al-2026-molecular-mechanisms-underlying-fccp-induced-mitophagyin-human-airway-smooth-muscle-cells-html.html
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epithelial-mesenchymal transition is associated with altered immune composition and cytotoxic function in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13374390/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KRAS-mediated CCDC6 degradation drives xCT upregulation and ferroptosis evasion
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    pmc.ncbi.nlm.nih.gov/articles/PMC13369686/
  11. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Genetic Deletion of Adenosine <fc>A<sub>2A</sub></fc> Receptors Attenuates Aged‐Related Alterations of Glial Cells Morphology and of Inflammasome in the Hippocampus and Prefrontal Cortex of Mice
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    onlinelibrary.wiley.com/doi/10.1002/glia.70197
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    Paternal exposure to chlorpyrifos disrupts protein regulation and abolishes PKCβ signaling in learning‑related neural circuits
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    sciencedirect.com/science/article/pii/S0161813X26001270
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss
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    pmc.ncbi.nlm.nih.gov/articles/PMC13318054/
  14. Jun 2026
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Circulating sphingosine-1-phosphate depletion is associated with endothelial activation and altered brain-endothelial S1P pathway expression in ischemic stroke
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    pmc.ncbi.nlm.nih.gov/articles/PMC13285081/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    WEE1 kinase inhibition to overcome acquired resistance to targeted therapies in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13269805/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeted KRASG12V Degradation in vivo Elicits Lung Adenocarcinoma Regression with Subsequent Relapse from Dysregulated Proteolysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC7619155/
  18. www.sciencedirect.com www.sciencedirect.com
    The HDAC Inhibitor RM-3-22 Suppresses Triple-Negative Breast Cancer by Uncoupling Autophagy to Drive FSP1-Dependent Ferroptosis
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    sciencedirect.com/science/article/pii/S1931524426001210
  19. May 2026
  20. www.biorxiv.org www.biorxiv.org
    YY1 Binding Motif at Upstream of Rep/Cap Increases AAV Yield and Full Capsids
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    biorxiv.org/content/10.64898/2026.05.21.726733v1
  21. link.springer.com link.springer.com
    Autophagy-lysosomal dependency defines a vulnerable physiological state in drug-tolerant persister cells of triple-negative breast cancer
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    link.springer.com/article/10.1007/s10495-026-02310-5
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dietary Fat Content Influences PanIN Progression and Pancreatic Cancer Development in Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC13139957/
  23. Apr 2026
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Myofibroblasts induce neuroplasticity to promote pancreatic inflammation and cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13102267/
  25. 54.241.53.176 54.241.53.176
    cd-25-1337-html.html
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    P21-positive senescent stromal cells promote prostate cancer immune suppression and progression that can be reversed by senolytic therapy
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    aacrjournals.org/cancerdiscovery/article/16/3/571/774737/p21-Positive-Senescent-Stromal-Cells-Promote
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    Inherent Lipid Composition Abnormalities in Astrocytes Associated with Late-Onset Alzheimer’s Disease (LOAD)
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    mdpi.com/2073-4409/15/6/549
  28. onlinelibrary.wiley.com onlinelibrary.wiley.com
    CCL26-Mediated Modulation of Endothelial Secretome by Hypoxia-Induced Tumor-Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer
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    onlinelibrary.wiley.com/doi/full/10.1002/hed.70259
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutational Signatures and Clonal Hematopoiesis in Intestinal Metaplasia across Countries with Varying Stomach Cancer Incidence
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    pmc.ncbi.nlm.nih.gov/articles/PMC13056296/
  30. link.springer.com link.springer.com
    Inflammaging-associated mitochondrial degeneration occurs in hypoglossal motor neurons prior to tongue muscle
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    link.springer.com/article/10.1007/s11357-026-02226-7
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    Genetic deletion of adenosine A2A receptors attenuates memory deterioration and alterations of synaptic plasticity and metabolic controllers in the hippocampus and prefrontal cortex of aged mice
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    link.springer.com/article/10.1007/s11357-026-02219-6
  32. Mar 2026
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chemoradiation Reprograms Tumor Cells and the Immune Microenvironment in Cervical Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13007708/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Medium-Chain Fatty Acid Receptor GPR84 Modulates Cytotoxic CD8 T cells Antitumor Immunity Through Metabolic Reprogramming
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    pmc.ncbi.nlm.nih.gov/articles/PMC12990994/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CF10 Displays Improved Synergy with Oxaliplatin in TP53-Null and Wild-Type CRC Cells from Increased Top1cc and Replication Stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC12984549/
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    Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy
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    sciencedirect.com/science/article/pii/S009286742600173X
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuroprotection From Intracerebral Hemorrhage Following Pharmacological Inhibition of GSK3β Depends on HFE Gene Status
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    pmc.ncbi.nlm.nih.gov/articles/PMC12954159/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    S6K1 Modulates STAT3 Activation to Promote Resistance to Radiotherapy in Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12940830/
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    Targeting peptidyl-arginine deiminase 4 suppresses SARS-CoV-2 replication and modulates the inflammatory response
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    sciencedirect.com/science/article/pii/S258900422600413X
  40. Feb 2026
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Unraveling Network Pharmacology‐Based Therapeutics of Anthranilate Sulfonamides via Sirtuins/FOXO3a Cascade in Alzheimer's Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12920268/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of CTLH component MAEA impairs DNA repair and replication and leads to developmental delay
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    pmc.ncbi.nlm.nih.gov/articles/PMC12905269/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    N‐Truncated Superoxide Dismutase‐1 in Cerebrospinal Fluid Is Folded and Active
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    pmc.ncbi.nlm.nih.gov/articles/PMC12887930/
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    Netrin-1 Promotes Pancreatic Tumorigenesis and Innervation through NEO1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12885529/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cyclic di-GMP suppresses cancer metastasis by targeting proteasome 26S subunit non-ATPase 3 independently of STING
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    pmc.ncbi.nlm.nih.gov/articles/PMC12868630/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aberrant Hippo-YAP/TEAD Signaling Drives Malignant Transcriptional Reprogramming in External Auditory Canal Squamous Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12862246/
  47. Jan 2026
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Role of the ETV5/p38 signaling axis in aggressive thyroid cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12818543/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Wilm’s Tumor 1-Expressing Stromal Cells Promote Pancreatic Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12809115/
  50. 54.241.53.176 54.241.53.176
    2026.01.07.694713v1.full-html.html
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  51. www.biorxiv.org www.biorxiv.org
    Reverse molecular pharmacology identifies the non-canonical axis of IRAK as a chemoresistance factor in neuroblastoma
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    biorxiv.org/content/10.64898/2026.01.09.697473v1
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    Candida albicans drives colorectal cancer progression by inducing hypoxia signaling
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    elifesciences.org/reviewed-preprints/108665
  53. Dec 2025
  54. www.sciencedirect.com www.sciencedirect.com
    Astrocytic GABA controls fidelity of temporal cortical processing in Fragile X Syndrome
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    sciencedirect.com/science/article/pii/S0969996125004504
  55. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    TDP-43 dysfunction compromises UPF1-dependent mRNA metabolism in ALS
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    sciencedirect.com:5037/science/article/pii/S0896627325008487
  56. Nov 2025
  57. www.embopress.org www.embopress.org
    Inhibiting cholesterol synthesis halts rhabdomyosarcoma growth via ER stress and cell cycle arrest
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    embopress.org/doi/10.1038/s44321-025-00336-x
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Altered GABAergic Homeostasis in the Striatum of Dopamine Transporter Knockout Rats
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    pmc.ncbi.nlm.nih.gov/articles/PMC12613098/
  59. www.biorxiv.org www.biorxiv.org
    Acute AMPK activation does not adequately stimulate insulin signaling in skeletal muscle models of Myotonic Dystrophy Type 1
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    biorxiv.org/content/10.1101/2025.11.04.686135v1
  60. Oct 2025
  61. www.biorxiv.org www.biorxiv.org
    Epithelial-Mesenchymal Transition is Associated with Altered Immune Composition and Cytotoxic Function in Triple-Negative Breast Cancer
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    biorxiv.org/content/10.1101/2025.10.22.683714v1
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    Cryo-EM reveals how ASX-173 inhibits human asparagine synthetase to activate the integrated stress response
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    biorxiv.org/content/10.1101/2025.10.16.682859v2
  63. Sep 2025
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    ER stress tolerance is regulated by copper-dependent PERK kinase activity
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    High-throughput bioprinting to produce micropatterened neuroepithelial tissues and model TSC2-deficient brain malformations
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    sciencedirect.com/science/article/pii/S2667237525002139
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    Neurons sequester the cholesterol-inhibiting TFEB in oligodendrocyte cytoplasm to safeguard myelination and neural function
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  67. Aug 2025
  68. www.medrxiv.org www.medrxiv.org
    Specific Lipid Abnormalities Are Inherently Associated with Late-Onset Alzheimer’s Disease
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    medrxiv.org/content/10.1101/2025.08.08.25333304v1
  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    5-HT6 Receptor Inverse Agonists Modulate Diabetic Neuropathic Pain in Female Rats: Evidence for 5-HT6 Receptor Constitutive Activity
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70179
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70107
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    Methylphenidate triggers retinal oxidative stress and mitochondrial dysfunction under physiological conditions but has beneficial effects in inflammatory settings
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    sciencedirect.com/science/article/pii/S0028390825003314
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The CCL2-CCR2 axis drives neuromuscular denervation in amyotrophic lateral sclerosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12316999/
  73. Jul 2025
  74. www.oaepublish.com www.oaepublish.com
    CF10/LV overcomes acquired resistance to 5-FU/LV in colorectal cancer cells through downregulation of the c-Myc/ABCB5 axis
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  75. rupress.org rupress.org
    Ubiquitin chain variability directs substrates of the Tul1 ubiquitin ligase complex to different degradation pathways
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    rupress.org/jcb/article/224/9/e202312133/278137/Ubiquitin-chain-variability-directs-substrates-of
  76. Jun 2025
  77. rupress.org rupress.org
    Gut dysbiosis from high-salt diet promotes glioma via propionate-mediated TGF-β activation
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    rupress.org/jem/article/222/8/e20241135/277968/Gut-dysbiosis-from-high-salt-diet-promotes-glioma
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    SOD1 Protein Content in Human Central Nervous System and Peripheral Tissues
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70136
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Store-operated Ca2+ entry is involved in endothelium-to-mesenchymal transition in lung vascular endothelial cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12169631/
  80. 52.53.155.43 52.53.155.43
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  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In Vitro Anticancer Activity of Phytol on Human Non-Small Cell Lung Cancer A549 Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12141803/
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    In Vitro Anticancer Activity of Phytol on Human Non-Small Cell Lung Cancer A549 Cells
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    journals.sagepub.com/doi/full/10.1177/15347354251344592
  83. May 2025
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-resolution transcriptional impact of AIRE: effects of pathogenic variants p.Arg257Ter, p.Cys311Tyr, and polygenic risk variant p.Arg471Cys
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    pmc.ncbi.nlm.nih.gov/articles/PMC12053179/
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Memory T‐Cell Phenotype in Cutaneous T‐Cell Lymphoma Is Modified by Germline Gene Gametocyte Specific Factor 1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12078864/
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    Peroxisomes are critical for a unique metabolic demand and survival of alveolar macrophages
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    sciencedirect.com/science/article/pii/S2211124725003948
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modulation of GABAergic System in a Chicken Retinal Ischemic Model: The Role of Chloride Cotransporters
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    pmc.ncbi.nlm.nih.gov/articles/PMC12067523/
  88. Apr 2025
  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impact of heterologous expression of Cannabis sativa tetraketide synthase on Phaeodactylum tricornutum metabolic profile
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    pmc.ncbi.nlm.nih.gov/articles/PMC11969993/
  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Both Proteins/Peptides and Non-Proteins/Peptides in Larval Oral Secretions of a Chewing Herbivore Function as Elicitors That Induce Plant Defenses
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    onlinelibrary.wiley.com/doi/10.1111/pce.15523
  91. Mar 2025
  92. academic.oup.com academic.oup.com
    Homeodomain protein PRRX1 anchors the Ku heterodimers at DNA double-strand breaks to promote nonhomologous end-joining
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    academic.oup.com/nar/article/53/6/gkaf200/8089753
  93. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The costimulatory domain influences CD19 CAR-T cell resistance development in B-cell malignancies
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    pmc.ncbi.nlm.nih.gov/articles/PMC11908201/
  94. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol to identify genes important for Candida albicans fitness in diverse environmental conditions using pooled bar-seq screening approach
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    pmc.ncbi.nlm.nih.gov/articles/PMC11889967/
  95. Feb 2025
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    A novel human SDHA‑knockout cell line model for the functional analysis of clinically‑relevant SDHA variants
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    aacrjournals.org/clincancerres/article/30/23/5399/750191/A-Novel-Human-SDHA-Knockout-Cell-Line-Model-for
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    Aβ*56 is present in brain extracts enriched for extracellular proteins
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  99. Jan 2025
  100. www.sciencedirect.com www.sciencedirect.com
    Endocrine-targeting therapies shift the breast microbiome to reduce estrogen receptor-α breast cancer risk
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    sciencedirect.com/science/article/pii/S2666379124006517
  101. Dec 2024
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    Expanding GABAergic Neuronal Diversity in iPSC-Derived Disease Models
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  168. May 2022
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  181. Mar 2021
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