78 Matching Annotations
  1. Aug 2025
  2. www.nature.com www.nature.com
    Thymic epithelial cells amplify epigenetic noise to promote immune tolerance
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    nature.com/articles/s41586-025-09424-x
  3. www.medrxiv.org www.medrxiv.org
    Adapting Clinical Chemistry Plasma as a Source for Liquid Biopsies
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    medrxiv.org/content/10.1101/2025.08.13.25333564v1
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Oxygen-induced stress reveals context-specific gene regulatory effects in human brain organoids
    2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12315710/
  5. Jul 2025
  6. www.nature.com www.nature.com
    NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity
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    nature.com/articles/s41586-025-09303-5
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A universal chimeric antigen receptor (CAR)–fragment antibody binder (FAB) split system for cancer immunotherapy
    2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12227065/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatially Varying Selection Amplifies Intrapopulation Differentiation Among Phenotypic Traits in the Rocky‐Shore Mussel, Mytilus californianus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12207488/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Direct inhibition of tumor hypoxia response with synthetic transcriptional repressors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12206482/
  10. Jun 2025
  11. www.nature.com www.nature.com
    Radiation-induced amphiregulin drives tumour metastasis
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    nature.com/articles/s41586-025-08994-0
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comparative transcriptomics of iPSC-derived cardiomyocytes in a high and a low altitude population
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    pmc.ncbi.nlm.nih.gov/articles/PMC12157700/
  13. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/bf0f2a9c147624ca7b182a2a5608426c90ea27fc/PDF-html.html
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Mediator Kinase Module regulates cell cycle re-entry and transcriptional responses following DNA damage
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    pmc.ncbi.nlm.nih.gov/articles/PMC12139960/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PARP-1 as a novel target in endocrine-resistant breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12168341/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic, developmental, and neural changes underlying the evolution of butterfly mate preference
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    pmc.ncbi.nlm.nih.gov/articles/PMC12136153/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiplex gene editing models of del(7q) reveal combined CUX1 and EZH2 loss drives clonal expansion and drug resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12067884/
  18. May 2025
  19. 52.53.155.43 52.53.155.43
    zqaf020-html.html
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    52.53.155.43/925af1839a885e19c84544f59cb5bfafc7ef234e/zqaf020-html.html
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Liver portal fibroblasts induce the functions of primary human hepatocytes in vitro
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    pmc.ncbi.nlm.nih.gov/articles/PMC12064700/
  21. Apr 2025
  22. elifesciences.org elifesciences.org
    Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis
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    elifesciences.org/reviewed-preprints/106492
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952453/
  24. Mar 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A shared gene but distinct dynamics regulate mimicry polymorphisms in closely related species
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11908123/
  26. www.science.org www.science.org
    Regulatory T cells constrain T cells of shared specificity to enforce tolerance during infection
    1
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    science.org/doi/10.1126/science.adk3248
  27. www.biorxiv.org www.biorxiv.org
    Emergent 3D genome reorganization from the stepwise assembly of transcriptional condensates
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    biorxiv.org/content/10.1101/2025.02.23.639564v1
  28. Nov 2024
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Radiotherapy Enhances Metastasis Through Immune Suppression by Inducing PD-L1 and MDSC in Distal Sites
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    pmc.ncbi.nlm.nih.gov/articles/PMC11062826/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TGF-β promotes the postselection thymic development and peripheral function of interferon-γ- producing iNKT cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC10592054/
  31. Sep 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oxygen-induced stress reveals context-specific gene regulatory effects in human brain organoids
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11398411/
  33. journals.lww.com journals.lww.com
    Long-term HBV infection of engineered cultures of induced... : Hepatology Communications
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    journals.lww.com/hepcomm/fulltext/2024/08010/long_term_hbv_infection_of_engineered_cultures_of.12.aspx
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unraveling the Role of Bromodomain and Extra-Terminal Proteins in Human Uterine Leiomyosarcoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11394028/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Validation studies and multi-omics analysis of Zhx2 as a candidate quantitative trait gene underlying brain oxycodone metabolite (oxymorphone) levels and behavior
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    ncbi.nlm.nih.gov/pmc/articles/PMC11383981/
  36. Aug 2024
  37. www.pnas.org www.pnas.org
    Reduced Satb1 expression predisposes CD4+ T conventional cells to Treg suppression and promotes transplant survival
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    pnas.org/doi/10.1073/pnas.2205062119
  38. Jul 2024
  39. link.springer.com link.springer.com
    Targeting Bromodomain-Containing Protein 9 in Human Uterine Fibroid Cells
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    link.springer.com/article/10.1007/s43032-024-01608-6
  40. Jun 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CUX1 regulates human hematopoietic stem cell chromatin accessibility via the BAF complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC11163479/
  42. Apr 2024
  43. www.nature.com www.nature.com
    PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape
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    nature.com/articles/s41590-024-01807-y
  44. Mar 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The endogenous Mtv8 locus and the immunoglobulin repertoire
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    ncbi.nlm.nih.gov/pmc/articles/PMC10948529/
  46. Feb 2024
  47. www.mdpi.com www.mdpi.com
    Transcriptomic Analysis of Postnatal Rat Carotid Body Development
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    mdpi.com/2073-4425/15/3/302
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Supergene evolution via gain of auto-regulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802445/
  49. Jan 2024
  50. www.nature.com www.nature.com
    Loss of thymocyte competition underlies the tumor suppressive functions of the E2a transcription factor in T-ALL
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    nature.com/articles/s41375-023-02123-4
  51. www.mdpi.com www.mdpi.com
    Bromodomain-Containing Protein 9 Regulates Signaling Pathways and Reprograms the Epigenome in Immortalized Human Uterine Fibroid Cells
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    mdpi.com/1422-0067/25/2/905
  52. link.springer.com link.springer.com
    Transcriptomic signatures of individual cell types in cerebral cavernous malformation
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    link.springer.com/article/10.1186/s12964-023-01301-2
  53. Dec 2023
  54. www.nature.com www.nature.com
    ERα/PR crosstalk is altered in the context of the ERα Y537S mutation and contributes to endocrine therapy-resistant tumor proliferation
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    nature.com/articles/s41523-023-00601-7
  55. www.biorxiv.org www.biorxiv.org
    The endogenous Mtv8 locus and the immunoglobulin repertoire
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    biorxiv.org/content/10.1101/2023.11.24.567955v1
  56. Oct 2023
  57. link.springer.com link.springer.com
    Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice
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    link.springer.com/article/10.1186/s40478-023-01661-3
  58. Sep 2023
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gut microbes and the liver circadian clock partition glucose and lipid metabolism
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    ncbi.nlm.nih.gov/pmc/articles/PMC10503806/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide Mapping Implicates 5-Hydroxymethylcytosines in Diabetes Mellitus and Alzheimer’s Disease
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10490934/
  61. academic.oup.com academic.oup.com
    Acute and Long-Term Consequences of Co-opted doublesex on the Development of Mimetic Butterfly Color Patterns
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    academic.oup.com/mbe/article/40/9/msad196/7260046
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGFβ signaling links early life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10492698/
  63. www.nature.com www.nature.com
    Kunitz-type protease inhibitor TFPI2 remodels stemness and immunosuppressive tumor microenvironment in glioblastoma
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    nature.com/articles/s41590-023-01605-y
  64. Aug 2023
  65. 52.53.155.43 52.53.155.43
    Bromodomain Containing 9 Regulates Signaling Pathways and Reprograms the Epigenome in Human Uterine Fibroid Cells
    1
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    52.53.155.43/0d1eedff7a58f6e635f082ef0f4c0fef026770f9/preprints202307.1154.v1-html.html
  66. Jun 2023
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGFβ signaling links early-life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10274956/
  68. www.sciencedirect.com www.sciencedirect.com
    Epithelial tissue confinement inhibits cell growth and leads to volume-reducing divisions
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    sciencedirect.com/science/article/pii/S1534580723002666
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10260022/
  70. May 2023
  71. www.mdpi.com www.mdpi.com
    The Functional Role and Regulatory Mechanism of FTO m6A RNA Demethylase in Human Uterine Leiomyosarcoma
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    mdpi.com/1422-0067/24/9/7957
  72. www.biorxiv.org www.biorxiv.org
    Loss of thymocyte competition underlies the tumor suppressive functions of the E2a transcription factor in T lymphocyte acute lymphoblastic leukemia
    1
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    biorxiv.org/content/10.1101/2023.04.23.537993v1
  73. Apr 2023
  74. journals.plos.org journals.plos.org
    Polyamines and eIF5A hypusination facilitate SREBP2 synthesis and cholesterol production leading to enhanced enterovirus attachment and infection
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    journals.plos.org/plospathogens/article
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants
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    ncbi.nlm.nih.gov/pmc/articles/PMC10104900/
  76. www.mdpi.com www.mdpi.com
    VEGF Induces Expression of Genes That Either Promote or Limit Relaxation of the Retinal Endothelial Barrier
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    mdpi.com/1422-0067/24/7/6402
  77. Feb 2023
  78. www.nature.com www.nature.com
    Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells
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    nature.com/articles/s41388-023-02612-x
  79. Nov 2022
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Asymmetrical forward and reverse developmental trajectories determine molecular programs of B cell antigen receptor editing
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    ncbi.nlm.nih.gov/pmc/articles/PMC9636592/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1α/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9600248/
  82. Oct 2022
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Evolution of immune genes is associated with the Black Death
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    pmc.ncbi.nlm.nih.gov/articles/PMC9580435/
  84. Sep 2022
  85. journals.asm.org journals.asm.org
    SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1α/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells
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    journals.asm.org/doi/10.1128/mbio.02415-22
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms
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    ncbi.nlm.nih.gov/pmc/articles/PMC8414261/
  87. Aug 2022
  88. www.sciencedirect.com www.sciencedirect.com
    NF-κB memory coordinates transcriptional responses to dynamic inflammatory stimuli
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    sciencedirect.com/science/article/pii/S2211124722009688
  89. Jul 2022
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    https://biorxiv.org/cgi/content/10.1101/2021.12.30.474519
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    ncbi.nlm.nih.gov/pmc/articles/PMC9275661/
  91. May 2022
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ancestry effects on the response to viral infection are pervasive but cell type-specific
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    ncbi.nlm.nih.gov/pmc/articles/PMC8957271/
  93. journals.plos.org journals.plos.org
    Dnmt1a is essential for gene body methylation and the regulation of the zygotic genome in a wasp
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    journals.plos.org/plosgenetics/article
  94. www.science.org www.science.org
    Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses
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    science.org/doi/10.1126/sciadv.abi6110
  95. Apr 2022
  96. insight.jci.org insight.jci.org
    Mutant ANP induces mitochondrial and ion channel remodeling in a human iPSC–derived atrial fibrillation model
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    insight.jci.org/articles/view/155640
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncogenic and Tumor Suppressor Functions for Lymphoid Enhancer Factor 1 in E2a-/- T Acute Lymphoblastic Leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8971981/
  98. Mar 2022
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC8940177/
  100. Jan 2022
  101. www.nature.com www.nature.com
    CRISPR screening in human hematopoietic stem and progenitor cells reveals an enrichment for tumor suppressor genes within chromosome 7 commonly deleted regions
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    nature.com/articles/s41375-021-01491-z
  102. Dec 2021
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-Neutralization of Emerging SARS-CoV-2 Variants of Concern by Antibodies Targeting Distinct Epitopes on Spike
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    ncbi.nlm.nih.gov/pmc/articles/PMC8593667/
  104. Nov 2021
  105. journals.asm.org journals.asm.org
    Cross-Neutralization of Emerging SARS-CoV-2 Variants of Concern by Antibodies Targeting Distinct Epitopes on Spike
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    journals.asm.org/doi/abs/10.1128/mBio.02975-21
  106. Oct 2021
  107. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    Benchmarking sequencing methods and tools that facilitate the study of alternative polyadenylation
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-021-02502-z
  108. Aug 2021
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross neutralization of emerging SARS-CoV-2 variants of concern by antibodies targeting distinct epitopes on spike
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    ncbi.nlm.nih.gov/pmc/articles/PMC8312900/
  110. May 2021
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets
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    ncbi.nlm.nih.gov/pmc/articles/PMC8101792/
  112. Apr 2021
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    https://biorxiv.org/cgi/content/10.1101/2021.03.10.432967
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    ncbi.nlm.nih.gov/pmc/articles/PMC7987002/