Hypothesis

63 Matching Annotations

Aug 2025
www.biorxiv.org www.biorxiv.org

Using targeted therapy to promote a pro-inflammatory tumour microenvironment and anti-tumour immune response in high grade serous ovarian cancer

1
1. scibot 20 Aug 2025
  
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  RRID:SCR_019627
  
  DOI: 10.1101/2025.08.10.669554
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
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biorxiv.org/content/10.1101/2025.08.10.669554v1
journals.asm.org journals.asm.org

Inhibition of efflux pumps by FDA-approved drugs oxiconazole and sertaconazole restores antibiotic susceptibility in multidrug-resistant S. aureus

1
1. scibot 08 Aug 2025
  
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  RRID:SCR_019627
  
  DOI: 10.1128/aac.00320-25
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
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journals.asm.org/doi/10.1128/aac.00320-25
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer

1
1. scibot 25 Jul 2025
  
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  RRID:SCR_019627
  
  DOI: 10.1158/2767-9764.CRC-24-0591
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12277487/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Indole-3-lactic acid suppresses colorectal cancer via metabolic reprogramming

1
1. scibot 31 May 2025
  
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  RRID:SCR_019627
  
  DOI: 10.1080/19490976.2025.2508949
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12118437/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Comparison of Shared Class I HLA-Bound Noncanonical Neoepitopes between Normal and Neoplastic Tissues of Pancreatic Adenocarcinoma

1
1. scibot 20 May 2025
  
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  RRID:SCR_019627
  
  DOI: 10.1158/1078-0432.CCR-24-2251
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12079097/
link.springer.com link.springer.com

SPP1 + macrophages cause exhaustion of tumor-specific T cells in liver metastases

1
1. scibot 19 May 2025
  
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  RRID:SCR_019627
  
  DOI: 10.1038/s41467-025-59529-0
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
  Curator: @scibot
  
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link.springer.com/article/10.1038/s41467-025-59529-0
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Efflux pump modulation by Montelukast and its roles in restoring antibiotic susceptibility in multidrug-resistant Staphylococcus aureus

1
1. scibot 29 Mar 2025
  
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  RRID:SCR_019627
  
  DOI: 10.1016/j.ebiom.2025.105658
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
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sciencedirect.com/science/article/pii/S2352396425001021
www.sciencedirect.com www.sciencedirect.com

Anti-vascular endothelial growth factor treatment potentiates immune checkpoint blockade through a BAFF- and IL-12-dependent reprogramming of the TME

1
1. scibot 20 Mar 2025
  
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  RRID:SCR_019627
  
  DOI: 10.1016/j.immuni.2025.02.017
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1074761325000846
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

DCAF13-mediated K63-linked ubiquitination of RNA polymerase I promotes uncontrolled proliferation in Breast Cancer

7
1. scibot 07 Feb 2025
  
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  RRID:SCR_019627
  
  DOI: 10.1038/s41467-025-55851-9
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_019627
  
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  RRID:SCR_019627
2. scibot 06 Feb 2025
  
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  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
3. scibot 05 Feb 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
4. scibot 04 Feb 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
5. scibot 03 Feb 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
6. scibot 02 Feb 2025
  
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  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
7. scibot 01 Feb 2025
  
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  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
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URL

pmc.ncbi.nlm.nih.gov/articles/PMC11718263/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

DCAF13-mediated K63-linked ubiquitination of RNA polymerase I promotes uncontrolled proliferation in Breast Cancer

17
1. scibot 31 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
2. scibot 30 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
3. scibot 29 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
4. scibot 28 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
5. scibot 27 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
6. scibot 26 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
7. scibot 25 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
8. scibot 24 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
9. scibot 23 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
10. scibot 22 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
11. scibot 21 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
12. scibot 20 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
13. scibot 19 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
14. scibot 18 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
15. scibot 17 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
16. scibot 16 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
17. scibot 15 Jan 2025
  
  in Public
  
  RRID:SCR_019627
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:SCR_019627
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pmc.ncbi.nlm.nih.gov/articles/PMC11718263/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Therapeutic Targeting and Structural Characterization of a Sotorasib-Modified KRAS G12C–MHC I Complex Demonstrate the Antitumor Efficacy of Hapten-Based Strategies

1
1. scibot 25 Jan 2025
  
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  RRID:SCR_019627
  
  DOI: 10.1158/0008-5472.CAN-24-2450
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11733532/
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 04 Jan 2025
  
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  RRID:SCR_019627
  
  DOI: 10.1158/1078-0432.ccr-24-2251
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
  Curator: @scibot
  
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52.53.155.43/552ebf82c7b63a71fc3637cda550c2b6bc512688/PDF-html.html
Dec 2024
52.53.155.43 52.53.155.43

can-24-2450-html.html

1
1. scibot 19 Dec 2024
  
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  RRID:SCR_019627
  
  DOI: 10.1158/0008-5472.can-24-2450
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
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52.53.155.43/eda542f05a259fcd2586bec9365306e8eda4954b/can-24-2450-html.html
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pretargeted Radioimmunotherapy with the Novel Anti-oxMIF/HSG Bispecific Antibody ON105 Results in Significant Tumor Regression in Murine Models of Cancer

1
1. scibot 12 Sep 2024
  
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  RRID:SCR_019627
  
  DOI: 10.1158/1535-7163.MCT-24-0083
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11372362/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Adipose microenvironment promotes hypersialylation of ovarian cancer cells

1
1. scibot 19 Aug 2024
  
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  SCR_019627
  
  DOI: 10.3389/fonc.2024.1432333
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11299042/
Jun 2024
www.sciencedirect.com www.sciencedirect.com

Protein-energy restriction-induced lipid metabolism disruption causes stable-to-progressive disease shift in Mycobacterium avium-infected female mice

1
1. scibot 21 Jun 2024
  
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  RRID:SCR_019627
  
  DOI: 10.1016/j.ebiom.2024.105198
  
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sciencedirect.com/science/article/pii/S2352396424002330
May 2024
www.biorxiv.org www.biorxiv.org

Adipose microenvironment promotes hypersialylation of ovarian cancer cells

1
1. scibot 24 May 2024
  
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  RRID:SCR_019627
  
  DOI: 10.1101/2024.05.13.593990
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
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biorxiv.org/content/10.1101/2024.05.13.593990v1
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma

1
1. scibot 17 May 2024
  
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  RRID:SCR_019627
  
  DOI: 10.1158/0008-5472.CAN-23-2521
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11094425/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The crosstalk between intestinal microbiota and MDSCs fuels colitis associated cancer development

1
1. scibot 18 Apr 2024
  
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  RRID:SCR_019627
  
  DOI: 10.1158/2767-9764.CRC-23-0421
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11017962/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cancer-associated fibroblast-specific expression of the matricellular protein CCN1 coordinates neovascularization and stroma deposition in melanoma metastasis

1
1. scibot 02 Mar 2024
  
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  RRID:SCR_019627
  
  DOI: 10.1158/2767-9764.CRC-23-0571
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10898341/
Nov 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells

1
1. scibot 02 Nov 2023
  
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  SCR_019627
  
  DOI: 10.1084/jem.20222178
  
  Resource: Beckman Coulter CytoFLEX Flow Cytometer (RRID:SCR_019627)
  
  Curator: @scibot
  
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Aug 2023
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Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin

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The newly engineered monoclonal antibody ON104, targeting the oxidized Macrophage Migration Inhibitory Factor (oxMIF), ameliorates clinical and histopathological signs of collagen-induced arthritis

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Jul 2023
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Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses

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May 2023
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Preclinical Evaluation of ON203, A Novel Bioengineered mAb Targeting Oxidized Macrophage Migration Inhibitory Factor as an Anticancer Therapeutic

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Sex-specific Phenotypes in the Aging Mouse Heart and Consequences for Chronic Fibrosis

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  DOI: 10.1152/ajpheart.00078.2022
  
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Sex-specific phenotypes in the aging mouse heart and consequences for chronic fibrosis

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Allosteric targeting resolves limitations of earlier LFA-1 directed modalities

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Feb 2023
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PINK1-mediated mitophagy promotes oxidative phosphorylation and redox homeostasis to induce drug-tolerant persister cancer cells

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Jan 2023
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Click-chemistry-based protocol to quantitatively assess fatty acid uptake by Mycobacterium tuberculosis in axenic culture and inside mouse macrophages

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SSRN-id4221334-html.html

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Impact of SARS-CoV-2 vaccination on systemic immune responses in people living with HIV

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Sep 2022
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Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair

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BCGΔBCG1419c increased memory CD8+ T cell-associated immunogenicity and mitigated pulmonary inflammation compared with BCG in a model of chronic tuberculosis

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Dhx38 regulates the maintenance and differentiation of erythro-myeloid progenitors and hematopoietic stem cells by alternative splicing

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NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins

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Jul 2022
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An in vivo biosafety-level-2-compatible model of Mycobacterium tuberculosis infection for drug susceptibility testing

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BPS Publications

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  DOI: 10.1111/bph.15838
  
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Mar 2022
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Local treatment of a pediatric osteosarcoma model with a 4-1BBL armed oncolytic adenovirus results in an antitumor effect and leads to immune memory

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  DOI: 10.1158/1535-7163.MCT-21-0565
  
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Activating Mucosal-Associated Invariant T cells Induces a Broad Antitumor Response

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  DOI: 10.1158/2326-6066.CIR-20-0925
  
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