130 Matching Annotations
  1. Jan 2026
  2. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226000751-main-html.html
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    54.241.53.176/8da98ac6332f753b8185d342a799be711da2a242/1-s2.0-S2589004226000751-main-html.html
  3. www.sciencedirect.com www.sciencedirect.com
    Altered hepatic metabolism in Down syndrome
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    sciencedirect.com/science/article/pii/S2211124725016079
  4. www.biorxiv.org www.biorxiv.org
    A Pan-Cancer Single-Cell Compendium of Intratumoural Heterogeneity
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    biorxiv.org/content/10.64898/2026.01.06.693992v1
  5. www.biorxiv.org www.biorxiv.org
    Reverse molecular pharmacology identifies the non-canonical axis of IRAK as a chemoresistance factor in neuroblastoma
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    biorxiv.org/content/10.64898/2026.01.09.697473v1
  6. 54.241.53.176 54.241.53.176
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  7. Dec 2025
  8. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    TDP-43 dysfunction compromises UPF1-dependent mRNA metabolism in ALS
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    sciencedirect.com:5037/science/article/pii/S0896627325008487
  9. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004225026057-main-html.html
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    54.241.53.176/5f497281d2892d538c291382ed51dd6345426f4d/1-s2.0-S2589004225026057-main-html.html
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Monounsaturated Fatty Acid Metabolism for Radiosensitization of KRAS Mutant 3D Lung Cancer Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12137014/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immunocompetent murine models recapitulate the heterogeneous tumor immune microenvironment of human liposarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12664306/
  12. Nov 2025
  13. www.sciencedirect.com www.sciencedirect.com
    Epigenetic profiling reveals key super-enhancer networks driving oncogenesis in HPV-positive HNSCC
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    sciencedirect.com/science/article/pii/S2589004225021728
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanisms of maternal antibody interference with rotavirus vaccination
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    pmc.ncbi.nlm.nih.gov/articles/PMC12623505/
  15. Oct 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intratumoral B cell and interferon signatures in newly diagnosed glioblastoma are associated with longer survival in patients treated with SurVaxM
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    pmc.ncbi.nlm.nih.gov/articles/PMC12511503/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD27 agonist antibodies mediate clinical responses through intratumoral stimulation in B-cell malignancies: multicenter RiVa trial
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618221/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Surgical and Blood-Based Minimal Residual Disease in Patients with Ovarian Cancer after First-line Therapy: Clinical Outcomes and Translational Opportunities
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485385/
  19. Sep 2025
  20. www.sciencedirect.com www.sciencedirect.com
    Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4
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    sciencedirect.com/science/article/pii/S1074761325004145
  21. www.sciencedirect.com www.sciencedirect.com
    Identification of novel type 1 and type 2 diabetes genes by co-localization of human islet eQTL and GWAS variants with colocRedRibbon
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    sciencedirect.com/science/article/pii/S2666979X25002605
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Parp7 generates an ADP-ribosyl degron that controls negative feedback of androgen signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402299/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An antibody-toxin conjugate targeting CD47 linked to the bacterial toxin listeriolysin O for cancer immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952976/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Plasma exosomes from individuals with type 2 diabetes drive breast cancer aggression in patient-derived organoids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12381303/
  25. Aug 2025
  26. www.sciencedirect.com www.sciencedirect.com
    Phase 1/2 trial of encorafenib, cetuximab, and nivolumab in microsatellite stable BRAFV600E metastatic colorectal cancer
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    sciencedirect.com/science/article/pii/S153561082500340X
  27. www.sciencedirect.com www.sciencedirect.com
    AI-driven multimodal algorithm predicts immunotherapy and targeted therapy outcomes in clear cell renal cell carcinoma
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    sciencedirect.com/science/article/pii/S2666379125003726
  28. www.sciencedirect.com www.sciencedirect.com
    Reconstructed cell-type-specific rhythms in human brain link Alzheimer’s pathology, circadian stress, and ribosomal disruption
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    sciencedirect.com/science/article/pii/S0896627325005173
  29. Jul 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human gut microbiome gene co-expression network reveals a loss in taxonomic and functional diversity in Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12289924/
  31. 52.53.155.43 52.53.155.43
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  32. www.biorxiv.org www.biorxiv.org
    A developmental program of early residency promotes the differentiation of divergent uterine NK cell subsets in humans
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    biorxiv.org/content/10.1101/2025.07.05.663267v1
  33. www.mdpi.com www.mdpi.com
    Clinical and Transcriptomic Characterization of Metastatic Hormone-Sensitive Prostate Cancer Patients with Low PTEN Expression
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    mdpi.com/1422-0067/26/13/6244
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Developmental pyrethroid exposure disrupts molecular pathways for MAP kinase and circadian rhythms in mouse brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC12232972/
  35. www.sciencedirect.com www.sciencedirect.com
    The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
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    sciencedirect.com/science/article/pii/S1074761325002481
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defining Non–small Cell Lung Cancer Tumor Microenvironment Changes at Primary and Acquired Immune Checkpoint Inhibitor Resistance Using Clinical and Real-World Data
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    pmc.ncbi.nlm.nih.gov/articles/PMC12207206/
  37. Jun 2025
  38. www.cell.com www.cell.com
    Neurodevelopmental hijacking of oligodendrocyte lineage programs drives glioblastoma infiltration
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    cell.com/developmental-cell/abstract/S1534-5807(25)00260-6
  39. www.sciencedirect.com www.sciencedirect.com
    Transcription factor T-bet regulates the maintenance and differentiation potential of lymph node and lung effector memory B cell subsets
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    sciencedirect.com/science/article/pii/S1074761325002420
  40. www.sciencedirect.com www.sciencedirect.com
    A hexamer tandem repeat RNA embedded within an SVA retrotransposon drives R-loop formation and neurodegeneration
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    sciencedirect.com/science/article/pii/S2211124725005832
  41. 52.53.155.43 52.53.155.43
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  43. May 2025
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12068872/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clear-Cell Renal Cell Carcinoma Molecular Subtypes Differ by African and European Genetic Similarity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12044083/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Heterogeneous Responses to High-Dose Testosterone in Castration-Resistant Prostate Cancer Tumors with Mixed Rb-Proficient and Rb-Deficient Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12046331/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic Screen in a Pre-Clinical Model of Sarcoma Development Defines Drivers and Therapeutic Vulnerabilities
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    pmc.ncbi.nlm.nih.gov/articles/PMC11530313/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic silencing of DNA sensing pathway by FOXM1 blocks stress ligand-dependent antitumor immunity and immune memory
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    pmc.ncbi.nlm.nih.gov/articles/PMC12037779/
  49. Apr 2025
  50. www.nature.com www.nature.com
    α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells
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    nature.com/articles/s41556-025-01658-1
  51. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Comparative single-cell transcriptomic profiling of patient-derived renal carcinoma cells in cellular and animal models of kidney cancer
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70022
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clinical and Translational Results from PORTER, a Multicohort Phase I Platform Trial of Combination Immunotherapy in Metastatic Castration-Resistant Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11995007/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Global changes in Staphylococcus aureus virulence and metabolism during colonization of healthy skin
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    pmc.ncbi.nlm.nih.gov/articles/PMC11977313/
  54. www.sciencedirect.com www.sciencedirect.com
    A common ground: an in silico assessment of the sources of intrinsic ex vivo resistance to venetoclax in acute myeloid leukemia
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    sciencedirect.com/science/article/pii/S2531137925000264
  55. aacrjournals.org aacrjournals.org
    Exploring B7-H4’s Role in Prostate Cancer Dormancy after Androgen Deprivation Therapy: Extracellular Matrix Interactions and Therapeutic Opportunities
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    aacrjournals.org/mcr/article/23/4/327/754237/Exploring-B7-H4-s-Role-in-Prostate-Cancer-Dormancy
  56. aacrjournals.org aacrjournals.org
    Phase 1/2 trial of XPO1 inhibitor selinexor plus docetaxel in previously treated, advanced KRAS mutant non-small cell lung cancer
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    aacrjournals.org/clincancerres/article/31/4/639/751730/Phase-I-II-Trial-of-Exportin-1-Inhibitor-Selinexor
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Early Neutrophil Activation in Psoriatic Skin at Relapse Following Dead Sea Climatotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11969059/
  58. Mar 2025
  59. elifesciences.org elifesciences.org
    Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson’s disease
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    elifesciences.org/reviewed-preprints/101035
  60. Feb 2025
  61. www.sciencedirect.com www.sciencedirect.com
    The endogenous antigen-specific CD8+ T cell repertoire is composed of unbiased and biased clonotypes with differential fate commitments
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    sciencedirect.com/science/article/pii/S1074761325000688
  62. 52.53.155.43 52.53.155.43
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  63. aacrjournals.org aacrjournals.org
    Epigenome reprogramming through H3K27 and H3K4 trimethylation as a resistance mechanism to DNA methylation inhibition in BRAFV600E-mutated colorectal cancer
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    aacrjournals.org/clincancerres/article/30/22/5166/749574/Epigenome-Reprogramming-Through-H3K27-and-H3K4
  64. aacrjournals.org aacrjournals.org
    Platinum-based chemotherapy induces opposing effects on immunotherapy response-related spatial and stromal biomarkers in the bladder cancer microenvironment
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    aacrjournals.org/clincancerres/article/30/18/4227/747456/Platinum-Based-Chemotherapy-Induces-Opposing
  65. www.sciencedirect.com www.sciencedirect.com
    Using multiomic integration to improve blood biomarkers of major depressive disorder: a case-control study
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    sciencedirect.com/science/article/pii/S2352396425000131
  66. www.sciencedirect.com www.sciencedirect.com
    Myofibroblasts emerge during alveolar regeneration following influenza-virus-induced lung injury
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    sciencedirect.com/science/article/pii/S2211124725000191
  67. Jan 2025
  68. link.springer.com link.springer.com
    Steatohepatitis-induced vascular niche alterations promote melanoma metastasis
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    link.springer.com/article/10.1186/s40170-025-00374-6
  69. www.sciencedirect.com www.sciencedirect.com
    Cytoplasmic mRNA decay controlling inflammatory gene expression is determined by pre-mRNA fate decision
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    sciencedirect.com/science/article/pii/S1097276525000012
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aberrant Activation of Wound-Healing Programs within the Metastatic Niche Facilitates Lung Colonization by Osteosarcoma Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11739783/
  71. 52.53.155.43 52.53.155.43
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  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RECQL4 affects MHC class II‐mediated signalling and favours an immune‐evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11734436/
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Tumor Immune Microenvironment and Therapeutic Efficacy of Trastuzumab Deruxtecan in Gastric Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11729160/
  74. 52.53.155.43 52.53.155.43
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  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    JAK inhibition decreases the autoimmune burden in Down syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC11687933/
  76. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nuclear respiratory factor-1 (NRF1) induction as a powerful strategy to deter mitochondrial dysfunction and senescence in mesenchymal stem cells
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    onlinelibrary.wiley.com/doi/10.1111/acel.14446
  77. 52.53.155.43 52.53.155.43
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  78. Dec 2024
  79. 52.53.155.43 52.53.155.43
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    Early downmodulation of tumor glycolysis predicts response to fasting-mimicking diet in triple-negative breast cancer patients
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    sciencedirect.com/science/article/pii/S1550413124004509
  81. Nov 2024
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  83. Oct 2024
  84. aacrjournals.org aacrjournals.org
    NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs
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    aacrjournals.org/cancerimmunolres/article/12/10/1421/748722/NK-Receptor-Signaling-Lowers-TCR-Activation
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biomarker analyses investigating disease biology and associations with outcomes in the JAVELIN Merkel 200 trial of avelumab in metastatic Merkel cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443199/
  86. Sep 2024
  87. www.sciencedirect.com www.sciencedirect.com
    Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
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    sciencedirect.com/science/article/pii/S0012160624002343
  88. May 2024
  89. www.cell.com www.cell.com
    The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
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    cell.com/immunity/fulltext/S1074-7613(24)00231-0
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor niche network-defined subtypes predict immunotherapy response of esophageal squamous cell cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11089351/
  91. elifesciences.org elifesciences.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
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    elifesciences.org/articles/90683
  92. Apr 2024
  93. www.sciencedirect.com www.sciencedirect.com
    ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection
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    sciencedirect.com/science/article/pii/S2211124724004844
  94. www.sciencedirect.com www.sciencedirect.com
    Generation of human cerebral organoids with a structured outer subventricular zone
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    sciencedirect.com/science/article/pii/S2211124724003590
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental pyrethroid exposure disrupts molecular pathways for MAP kinase and circadian rhythms in mouse brain
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    ncbi.nlm.nih.gov/pmc/articles/PMC10515776/
  96. Feb 2024
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10862846/
  98. www.sciencedirect.com www.sciencedirect.com
    Single-cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, aging, and disease
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    sciencedirect.com/science/article/pii/S2211124724001128
  99. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Multi-organ single-cell RNA sequencing in mice reveals early hyperglycemia responses that converge on fibroblast dysregulation
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202302003R
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative transcriptomic analysis of bovine mesenchymal stromal cells reveals tissue-source and species-specific differences
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    ncbi.nlm.nih.gov/pmc/articles/PMC10838956/
  101. link.springer.com link.springer.com
    Gestational diabetes augments group B Streptococcus infection by disrupting maternal immunity and the vaginal microbiota
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  103. Jan 2024
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  105. Dec 2023
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  108. Nov 2023
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    Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids
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  116. Sep 2023
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  118. Aug 2023
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  121. Jul 2023
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  125. Jun 2023
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  127. May 2023
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  129. Apr 2023
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  131. Mar 2023
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  135. Feb 2023
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  137. Jan 2023
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  142. Dec 2022
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  145. Nov 2022
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  149. Oct 2022
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  151. Sep 2022
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  153. Jun 2022
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  157. May 2022
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    Comprehensive profiling of myxopapillary ependymomas identifies a distinct molecular subtype with relapsing disease
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  160. Mar 2022
  161. elifesciences.org elifesciences.org
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  163. Feb 2022
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    Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target
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    FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons
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  166. Nov 2021
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    Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice
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  168. Oct 2021
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  170. Sep 2021
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  172. Jun 2021
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    Single-cell BCR and transcriptome analysis after influenza infection reveals spatiotemporal dynamics of antigen-specific B cells
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