153 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In situ APMV-4 vaccination primes systemic response to subtherapeutic dosing of aCTLA-4 in colorectal carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13629906/
  3. Sep 2026
  4. www.sciencedirect.com www.sciencedirect.com
    Gliomas phenocopy an inborn error of metabolism to drive neuronal activity and tumor growth
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    sciencedirect.com/science/article/pii/S009286742601010X
  5. Aug 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glycolytic enolase 1-induced H4K12 lactylation activates quiescent breast cancer stem-like cells in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13493833/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune dysregulation and exhaustion in EBV- associated hemophagocytic lymphohistiocytosis: insights from single-cell transcriptomics and TCR repertoire analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13485814/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Endometriosis-derived iPSCs reveal conserved stromal maturation and endocrine responsiveness
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    pmc.ncbi.nlm.nih.gov/articles/PMC13488922/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Viral mimicry redirects immunosuppressed colorectal tumour landscapes towards a proinflammatory and CMS1-like regenerative state
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    pmc.ncbi.nlm.nih.gov/articles/PMC13486658/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Archetype analysis of lung adenocarcinoma premalignancy links heterogeneity in premalignant lesions to diverging features of invasive disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC13455826/
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    RASA1 deficiency aggravates the lesion burden of cerebral cavernous malformations via the Ras/Raf/MAPK pathway
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    sciencedirect.com/science/article/pii/S2589004226025046
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Evaluation of Tissue from Patients with Prostate Cancer Identifies B7-H3 as an Androgen-Regulated, Broadly Expressed, Combinatorial Therapeutic Target
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    pmc.ncbi.nlm.nih.gov/articles/PMC13399116/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Temporal Genomic Analysis of Homogeneous Tumor Models Reveals Key Regulators of Immune Evasion in Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11873729/
  14. Jul 2026
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional Reprogramming by AP-1-Bound Cis-Regulatory Elements Is Associated with Melanoma Development
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    pmc.ncbi.nlm.nih.gov/articles/PMC13411661/
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    Gene expression adaptation of metastases to their host tissue
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    sciencedirect.com/science/article/pii/S258900422602122X
  17. 54.241.53.176 54.241.53.176
    can-25-4717-html.html
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    54.241.53.176/636ef19faf4a637a43b1def54fbc2860d6c10bd3/can-25-4717-html.html
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ATM Deficiency Induces TGFβ-Mediated Stromal Programming in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13370118/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Survival Genie 2: a next-generation web server for targeted and single-cell-based survival analyses
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    pmc.ncbi.nlm.nih.gov/articles/PMC13343920/
  20. aacrjournals.org aacrjournals.org
    USP20-Driven Cholesterol Metabolism Links Inflammatory Signaling to Malignancy and Stromal Co-evolution in Pancreatic Cancer
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    aacrjournals.org/cancerres/article/86/3/712/771921/USP20-Driven-Cholesterol-Metabolism-Links
  21. aacrjournals.org aacrjournals.org
    Subtyping-Directed Precision Treatment Refines Traditional One-Size-Fits-All Therapy for HR+/HER2- Breast Cancer
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    aacrjournals.org/cancerres/article/85/20/3983/766091/Subtyping-Directed-Precision-Treatment-Refines
  22. 54.241.53.176 54.241.53.176
    Arginine deprivation enhances ASS1-negative glioblastoma radiosensitivity via epigenetic silencing of DNA repair genes
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    54.241.53.176/3b1580221671e68b563bc25b1dd66e50af60765e/s41419-026-08920-w_reference-html.html
  23. Jun 2026
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    The Hippo Pathway is Dysregulated in Cancer-Associated Fibroblasts in Anti-PD-L1 Resistant Cancer
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    aacrjournals.org/cancerres/article/86/11/2592/785307/The-Hippo-Pathway-Is-Dysregulated-in-Cancer
  25. www.biorxiv.org www.biorxiv.org
    A targetable opioid/cancer associated fibroblast axis drives extracellular matrix remodeling and tumor aggressiveness in pancreatic cancer
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    biorxiv.org/content/10.64898/2026.05.20.726559v1
  26. aacrjournals.org aacrjournals.org
    Bevacizumab plus erlotinib in advanced solid cancers with Krebs cycle gene mutations: A multicenter phase II study (BRISK; KCSG AL22-16)
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    aacrjournals.org/clincancerres/article/32/2/291/771740/Bevacizumab-plus-Erlotinib-in-Advanced-Solid
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cellular neighborhoods govern antitumor T-cell infiltration following anti-CTLA-4 in melanoma with primary resistance to anti-PD-1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13274726/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A malignant subpopulation of H2AFZ+ cells interacts with myeloid cells to promote an anti-inflammatory microenvironment and drive hepatic metastasis, revealing an immunotherapeutic strategy for pancreatic ductal adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13266339/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PI3K and MAPK Signaling Nodes Serve as Divergent Drivers of Phenotypic Plasticity in Cancer-Associated Fibroblasts in Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13266349/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reductive death is averted by a conserved de novo lipogenic switch
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    pmc.ncbi.nlm.nih.gov/articles/PMC13386819/
  31. May 2026
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Three-Gene Interferon Signature Predicts Sustained Complete Remission in Pediatric AML Patients
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    pmc.ncbi.nlm.nih.gov/articles/PMC13162913/
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    Transcriptome-guided development of a fibrosis-reversal compound reduces skin scarring and allows regeneration via mitochondrial uncoupling
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    sciencedirect.com/science/article/pii/S2666379126002387
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PET/CT-Guided Neoadjuvant Tislelizumab Plus Chemotherapy/Chemoradiotherapy for Resectable Esophageal Squamous Cell Carcinoma: RATIONALE-213 Final Analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13176819/
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    Region-resolved integrative multi-omic characterization reveals diverse tumor and microenvironment features of pituitary neuroendocrine tumors
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    sciencedirect.com/science/article/pii/S1535947626000794
  36. www.nature.com www.nature.com
    Identification of a distinct cluster of LY6E+ macrophages in esophageal squamous cell carcinoma: functional phenotype, spatial interaction, and prognostic significance
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    nature.com/articles/s41416-026-03456-4
  37. www-cell-com.eproxy.lib.hku.hk www-cell-com.eproxy.lib.hku.hk
    Whole-genome doubling drives immune evasion by silencing antigen presentation
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    www-cell-com.eproxy.lib.hku.hk/cancer-cell/fulltext/S1535-6108(26)00218-7
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TENT5A Maintains MYC mRNA Stability to Enhance Osteosarcoma Stemness
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    pmc.ncbi.nlm.nih.gov/articles/PMC13136882/
  39. aacrjournals.org aacrjournals.org
    Intra-tumoral tertiary lymphoid structures characterized by a B cell-related signature elicit antitumor effect through HAPLN3 in hepatocellular carcinoma
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    aacrjournals.org/cancerimmunolres/article/14/5/771/784463/Intratumoral-Tertiary-Lymphoid-Structures
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptomic subgroups in soft tissue tumors correlate with morphologic subtype, genomic features, and outcome
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133608/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD27 expression is a clinically accessible biomarker for predicting immunotherapy response in melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133361/
  42. www.sciencedirect.com www.sciencedirect.com
    Tissue tension fosters macrophage-driven lipid peroxidation-induced DNA damage
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    sciencedirect.com/science/article/pii/S1535610826001765
  43. Apr 2026
  44. 54.241.53.176 54.241.53.176
    Supplementary file-html.html
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    54.241.53.176/4d06b1922c474219b22e5a7827bebd122dca3f2f/Supplementary file-html.html
  45. www.biorxiv.org www.biorxiv.org
    ARID1A deficiency unleashes centromeric RNA transcription to drive chromosomal instability and boosts PKMYT1 inhibitor efficacy via RNA sensing
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    biorxiv.org/content/10.64898/2026.04.11.717899v1
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    Immune infiltration is associated with distinct transcriptional states and metabolic profiles in chordomas
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  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    T Cell Receptor and Immune Gene Expression Pharmacodynamics for Durvalumab alone and with Tremelimumab or Bevacizumab in Unresectable Hepatocellular Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13056246/
  48. www.sciencedirect.com www.sciencedirect.com
    From clusters to clinic: an 8-gene signature combined with mucinous component stratifies benefit of anti-CTLA-4 addition to anti-PD-1 in dMMR/MSI-H metastatic colorectal cancer
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    sciencedirect.com/science/article/pii/S0959804926005113
  49. Mar 2026
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Composition and functional state of T and NK cells in the extramedullary myeloma tumor microenvironment
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012251/
  51. Feb 2026
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modulating the tumor immune phenotypes by radiotherapy: formulating and validating the combination therapy of radiation, PD-L1, and TIM-3 blockade in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12933762/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hypoxia Promotes an Adrenergic to Mesenchymal Transcriptional Program Transition in Neuroblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12928030/
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Progranulin promotes glioma progression via interaction with cathepsin D and serves as a diagnostic and prognostic biomarker
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    pmc.ncbi.nlm.nih.gov/articles/PMC12917043/
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    Hormonal rewiring of immunity during dietary restriction ensures host defense and systemic glucose conservation
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    sciencedirect.com/science/article/pii/S1074761326000026
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The molecular and functional landscape of resistance to FOLFIRI chemotherapy in metastatic colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12877753/
  57. 54.241.53.176 54.241.53.176
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    Immunogenomic Profiles of HIV-associated Classic Hodgkin Lymphoma from Malawi
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    sciencedirect.com/science/article/pii/S3050565825000204
  59. journals.plos.org journals.plos.org
    The lipid-metabolic enzyme HSD17B12 drives lysosomal degradation of PD-L1 potentiating anti-tumor immunity in a mouse model
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    journals.plos.org/plosbiology/article
  60. Jan 2026
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pyroptosis modulates multiple immune cell populations in targeted therapy–treated melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12851756/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel super-enhancer-driven lncRNA LINC00973 governs head and neck squamous cell carcinoma progression through EN2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12848070/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lazertinib with stereotactic body radiotherapy in oligometastatic EGFR-mutant non-small-cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12874586/
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clinicogenomic characterization of inflammatory breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12255483/
  65. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202516965
  66. Dec 2025
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tertiary lymphoid structure‐related RNA indicator as metastasis risk factor in nasopharyngeal carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12705341/
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immunocompetent murine models recapitulate the heterogeneous tumor immune microenvironment of human liposarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12664306/
  69. Nov 2025
  70. www.sciencedirect.com www.sciencedirect.com
    Trilaciclib triggers a neutrophil-related immune response and sensitizes non-small cell lung cancer to anti-PD-1 therapy
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    sciencedirect.com/science/article/pii/S2666379125005075
  71. Oct 2025
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-cancer Analyses Refine the Single-Cell Portrait of Tumor-Infiltrating Dendritic Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485386/
  73. Sep 2025
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A framework to mine laser microdissection-based omics data and uncover regulators of pancreatic cancer heterogeneity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12412123/
  75. link.springer.com link.springer.com
    Transcriptomic and microenvironment characteristics of triple-negative breast cancer under three different neoadjuvant treatment regimens
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    link.springer.com/article/10.1007/s10549-025-07810-7
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    Cancer cell and microenvironmental rewiring by ADAR1 loss impairs glioblastoma tumor growth and extends survival
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    sciencedirect.com/science/article/pii/S2211124725009222
  77. Aug 2025
  78. www.sciencedirect.com www.sciencedirect.com
    Phase 1/2 trial of encorafenib, cetuximab, and nivolumab in microsatellite stable BRAFV600E metastatic colorectal cancer
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    sciencedirect.com/science/article/pii/S153561082500340X
  79. Jul 2025
  80. www.mdpi.com www.mdpi.com
    Clinical and Transcriptomic Characterization of Metastatic Hormone-Sensitive Prostate Cancer Patients with Low PTEN Expression
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    mdpi.com/1422-0067/26/13/6244
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SpatialDeX is a Reference-Free Method for Cell Type Deconvolution of Spatial Transcriptomics Data in Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11695180/
  82. www.biorxiv.org www.biorxiv.org
    Spatial determinants of tumor cell dedifferentiation and plasticity in primary cutaneous melanoma
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    biorxiv.org/content/10.1101/2025.06.21.660851v1
  83. Jun 2025
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-Cell Transcriptomic Landscape Deciphers Intratumoral Heterogeneity and Subtypes of Acral and Mucosal Melanomas
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    pmc.ncbi.nlm.nih.gov/articles/PMC12163602/
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    Piezo1 senses hyphae and initiates host defense against pathogenic fungi
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    sciencedirect.com/science/article/pii/S2211124725006102
  86. 52.53.155.43 52.53.155.43
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  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increasing Stemness Drives Prostate Cancer Progression, Plasticity, Therapy Resistance and Poor Patient Survival
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    pmc.ncbi.nlm.nih.gov/articles/PMC12129099/
  88. May 2025
  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clear-Cell Renal Cell Carcinoma Molecular Subtypes Differ by African and European Genetic Similarity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12044083/
  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Heterogeneous Responses to High-Dose Testosterone in Castration-Resistant Prostate Cancer Tumors with Mixed Rb-Proficient and Rb-Deficient Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12046331/
  91. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11534535/
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    Immunosequencing identifies signatures of T cell responses for early detection of nasopharyngeal carcinoma
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    sciencedirect.com/science/article/pii/S1535610825001680
  93. Apr 2025
  94. aacrjournals.org aacrjournals.org
    Ancestral differences in anti-cancer treatment efficacy and their underlying genomic and molecular alterations
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    aacrjournals.org/cancerdiscovery/article/15/3/511/752115/Ancestral-Differences-in-Anticancer-Treatment
  95. aacrjournals.org aacrjournals.org
    Exploring B7-H4’s Role in Prostate Cancer Dormancy after Androgen Deprivation Therapy: Extracellular Matrix Interactions and Therapeutic Opportunities
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    aacrjournals.org/mcr/article/23/4/327/754237/Exploring-B7-H4-s-Role-in-Prostate-Cancer-Dormancy
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    A Phase II Study of Abemaciclib for Patients with Retinoblastoma-Positive, Metastatic Triple-Negative Breast Cancer
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    aacrjournals.org/clincancerres/article/31/8/1427/754531/A-Phase-II-Study-of-Abemaciclib-for-Patients-with
  97. aacrjournals.org aacrjournals.org
    The Prostaglandin EP4 Antagonist Vorbipiprant Combined with PD-1 Blockade for Refractory Microsatellite Stable Metastatic Colorectal Cancer: A Phase 1b/2a Trial
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    aacrjournals.org/clincancerres/article/31/4/649/751732/The-Prostaglandin-EP4-Antagonist-Vorbipiprant
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    KRIT1 heterozygous mutations are sufficient to induce a pathological phenotype in patient-derived iPSC models of cerebral cavernous malformation
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    sciencedirect.com/science/article/pii/S221112472500347X
  99. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Early Neutrophil Activation in Psoriatic Skin at Relapse Following Dead Sea Climatotherapy
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