106 Matching Annotations
  1. Aug 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Phase 1/2 trial of encorafenib, cetuximab, and nivolumab in microsatellite stable BRAFV600E metastatic colorectal cancer
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    sciencedirect.com/science/article/pii/S153561082500340X
  3. www.biorxiv.org www.biorxiv.org
    Genetic and Epigenetic Reprogramming of Transposable Elements Drives ecDNA-Mediated Metastatic Prostate Cancer
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    biorxiv.org/content/10.1101/2025.08.08.668693v1
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Evaluating Gene Fusions as Prognostic Biomarkers and Therapeutic Targets in Immune Checkpoint Blockade-Treated Advanced Melanoma: a Retrospective Analysis.
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    pmc.ncbi.nlm.nih.gov/articles/PMC12344778/
  5. Jul 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Circulating tumor DNA monitoring detects minimal residual disease and predicts outcomes in patients with esophageal adenocarcinoma or squamous cell carcinoma after esophagectomy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12290085/
  7. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225013999-main-html.html
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    52.53.155.43/891a207af4fcb3deab6b33f31b53b463731ffd29/1-s2.0-S2589004225013999-main-html.html
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    β-catenin functions as a molecular adapter for disordered cBAF interactions
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    sciencedirect.com/science/article/pii/S1097276525005763
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    Fragmentomic-based algorithm to computationally predict tumor-somatic, germline, and clonal hematopoiesis variant origin in liquid biopsy
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    sciencedirect.com/science/article/pii/S295019542500027X
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214874/
  11. Jun 2025
  12. www.sciencedirect.com www.sciencedirect.com
    Functional assessment of all ATM SNVs using prime editing and deep learning
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    sciencedirect.com/science/article/pii/S0092867425006348
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-Cell Transcriptomic Landscape Deciphers Intratumoral Heterogeneity and Subtypes of Acral and Mucosal Melanomas
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    pmc.ncbi.nlm.nih.gov/articles/PMC12163602/
  14. 52.53.155.43 52.53.155.43
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  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the Glucose–Insulin Link in Head and Neck Squamous Cell Carcinoma Induces Cytotoxic Oxidative Stress and Inhibits Cancer Growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12141995/
  16. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70054
  17. May 2025
  18. www.sciencedirect.com www.sciencedirect.com
    Cross-organ hierarchy of HLA molecular mismatches in donor-specific antibody development in solid organ transplantations
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    sciencedirect.com/science/article/pii/S2666379125002265
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic Plasticity Drives Carcinogenesis and Multi-Therapy Resistance in Multiple Myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12048002/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Social–Environmental Burden Is Associated with Increased Colorectal Cancer Mortality in Metropolitan Detroit
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    pmc.ncbi.nlm.nih.gov/articles/PMC12036821/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Germline pathogenic variants in DNA repair pathways: a key feature in a significant subset of translocation-associated sarcomas
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    pmc.ncbi.nlm.nih.gov/articles/PMC12059086/
  22. link.springer.com link.springer.com
    Tumor break load quantitates structural variant-associated genomic instability with biological and clinical relevance across cancers
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    link.springer.com/article/10.1038/s41698-025-00922-9
  23. www.sciencedirect.com www.sciencedirect.com
    Malignant Chondroblastoma: An Epigenetically Distinct Subtype of Chondroblastoma with a Predilection for the Skeletally Mature
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    sciencedirect.com/science/article/pii/S0893395225000869
  24. link.springer.com link.springer.com
    Trends in kidney cancer: exploring the impact of sex and age on stage of disease, and prognosis during the past three decades in Denmark—a DaRenCa study
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    link.springer.com/article/10.1007/s10654-025-01236-7
  25. www.sciencedirect.com www.sciencedirect.com
    Immunosequencing identifies signatures of T cell responses for early detection of nasopharyngeal carcinoma
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    sciencedirect.com/science/article/pii/S1535610825001680
  26. Apr 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LncRNA SLNCR phenocopies the E2F1 DNA binding site to promote melanoma progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12172627/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Impact of Li Fraumeni and Germline Retinoblastoma Mutations on Leiomyosarcoma Initiation, Outcomes and Genetic Testing Recommendations
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    pmc.ncbi.nlm.nih.gov/articles/PMC11479842/
  29. 52.53.155.43 52.53.155.43
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  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11959268/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962398/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non-invasive multi-cancer detection using DNA hypomethylation of LINE-1 retrotransposons
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    pmc.ncbi.nlm.nih.gov/articles/PMC11959274/
  33. 52.53.155.43 52.53.155.43
    1-s2.0-S2666364325000451-main-html.html
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  34. Mar 2025
  35. www.sciencedirect.com www.sciencedirect.com
    Metallophilic marginal zone macrophages cross-prime CD8+ T cell-mediated protective immunity against blood-borne tumors
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    sciencedirect.com/science/article/pii/S1074761325000949
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comparative Single-Cell Transcriptomics of Human Neuroblastoma and Preclinical Models Reveals Conservation of an Adrenergic Cell State
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    pmc.ncbi.nlm.nih.gov/articles/PMC11907193/
  37. www.sciencedirect.com www.sciencedirect.com
    Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures across the Alzheimer disease continuum
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    sciencedirect.com/science/article/pii/S0896627325001321
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impact of Co-mutations and Transcriptional Signatures in Non–Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial
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    pmc.ncbi.nlm.nih.gov/articles/PMC11911804/
  39. www.cmghjournal.org www.cmghjournal.org
    1-s2.0-S2352345X25000268-main-html.html
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    cmghjournal.org/article/S2352-345X(25)00026-8/fulltext
  40. Feb 2025
  41. aacrjournals.org aacrjournals.org
    Serotonin receptor HTR2B facilitates colorectal cancer metastasis via CREB1-ZEB1 axis mediated epithelial-mesenchymal transition
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    aacrjournals.org/mcr/article/22/6/538/745428/Serotonin-Receptor-HTR2B-Facilitates-Colorectal
  42. 52.53.155.43 52.53.155.43
    ccr-24-2669-html.html
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  43. aacrjournals.org aacrjournals.org
    Predictive and dynamic signature for anti-angiogenics in combination with PD-1 inhibitor in soft-tissue sarcoma: correlative studies linked to the IMMUNOSARC trial
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    aacrjournals.org/clincancerres/article/30/22/5192/749561/Predictive-and-Dynamic-Signature-for
  44. aacrjournals.org aacrjournals.org
    The Tumour Immune Microenvironment Drives Survival Outcomes and Therapeutic Response in an Integrated Molecular Analysis of Gastric Adenocarcinoma
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    aacrjournals.org/clincancerres/article/30/23/5385/750202/The-Tumor-Immune-Microenvironment-Drives-Survival
  45. aacrjournals.org aacrjournals.org
    Radiodensities of skeletal muscle and visceral adipose tissues are prognostic factors in clear cell renal cell carcinoma
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    aacrjournals.org/cebp/article/33/10/1375/748658/Radiodensities-of-Skeletal-Muscle-and-Visceral
  46. aacrjournals.org aacrjournals.org
    Th17 cells secrete TWEAK to trigger epithelial-mesenchymal transition and promote colorectal cancer liver metastasis
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    aacrjournals.org/cancerres/article/84/8/1352/742976/Th17-Cells-Secrete-TWEAK-to-Trigger-Epithelial
  47. Jan 2025
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RECQL4 affects MHC class II‐mediated signalling and favours an immune‐evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11734436/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clonal Hematopoiesis of Indeterminate Potential and its Association with Treatment Outcomes and Adverse Events in Patients with Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11713863/
  50. Dec 2024
  51. aacrjournals.org aacrjournals.org
    Genomic Landscape of ctDNA and Real-World Outcomes in Advanced Endometrial Cancer
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    aacrjournals.org/clincancerres/article/30/24/5657/750431/Genomic-Landscape-of-ctDNA-and-Real-World-Outcomes
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11628624/
  53. Nov 2024
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11532741/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A comprehensive in silico analysis and experimental validation of miRNAs capable of discriminating between lung adenocarcinoma and squamous cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11460580/
  56. Oct 2024
  57. www.thelancet.com www.thelancet.com
    Profiling steroid hormone landscape of bladder cancer reveals depletion of intratumoural androgens to castration levels: a cross-sectional study
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00395-5/abstract
  58. Sep 2024
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circulating Tumor DNA Assessment for Treatment Monitoring Adds Value to PSA in Metastatic Castration Resistant Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393539/
  60. www.sciencedirect.com www.sciencedirect.com
    Exon Skipping-based Subtyping of Colorectal Cancers
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    sciencedirect.com/science/article/pii/S0016508524053575
  61. Jul 2024
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure
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    ncbi.nlm.nih.gov/pmc/articles/PMC11238266/
  63. Jun 2024
  64. journals.plos.org journals.plos.org
    Analysis of animal-to-human translation shows that only 5% of animal-tested therapeutic interventions obtain regulatory approval for human applications
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    journals.plos.org/plosbiology/article
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early detection and diagnosis of cancer with interpretable machine learning to uncover cancer-specific DNA methylation patterns
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    ncbi.nlm.nih.gov/pmc/articles/PMC11186673/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Measurement of ctDNA Tumor Fraction Identifies Informative Negative Liquid Biopsy Results and Informs Value of Tissue Confirmation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11145175/
  67. May 2024
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolomics for early pancreatic cancer detection in plasma samples from a Swedish prospective population-based biobank
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094504/
  69. www.sciencedirect.com www.sciencedirect.com
    Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma
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    sciencedirect.com/science/article/pii/S1535610824001363
  70. Apr 2024
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omics analysis reveals immune features associated with immunotherapy benefit in squamous cell lung cancer patients from Phase III Lung-MAP S1400I trial
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    ncbi.nlm.nih.gov/pmc/articles/PMC11016892/
  72. Mar 2024
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures for asymptomatic and symptomatic Alzheimer’s disease.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10896368/
  74. Feb 2024
  75. aacrjournals.org aacrjournals.org
    Comparative Genomic Analysis and Clinical Outcomes of BRAF-mutated Advanced Biliary Tract Cancers
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    aacrjournals.org/clincancerres/article/29/23/4853/730212/Comparative-Genomic-Analysis-and-Clinical-Outcomes
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10527051/
  77. www.nature.com www.nature.com
    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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    nature.com/articles/s41467-024-45067-8
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
  79. Jan 2024
  80. link.springer.com link.springer.com
    Molecular characteristics and improved survival prediction in a cohort of 2023 ependymomas
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    link.springer.com/article/10.1007/s00401-023-02674-x
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIB3, as a robust prognostic biomarker for HNSC, is associated with poor immune infiltration and cancer cell immune evasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10791810/
  82. www.nature.com www.nature.com
    A new genomic framework to categorize pediatric acute myeloid leukemia
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    nature.com/articles/s41588-023-01640-3
  83. Dec 2023
  84. www.mdpi.com www.mdpi.com
    High Expression of THY1 in Intestinal Gastric Cancer as a Key Factor in Tumor Biology: A Poor Prognosis-Independent Marker Related to the Epithelial–Mesenchymal Transition Profile
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    mdpi.com/2073-4425/15/1/28
  85. www.sciencedirect.com www.sciencedirect.com
    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S1535610823004014
  86. 52.53.155.43 52.53.155.43
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  87. Nov 2023
  88. www.mdpi.com www.mdpi.com
    Integrated Network Analysis of microRNAs, mRNAs, and Proteins Reveals the Regulatory Interaction between hsa-mir-200b and CFL2 Associated with Advanced Stage and Poor Prognosis in Patients with Intestinal Gastric Cancer
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    mdpi.com/2072-6694/15/22/5374
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer-prone Phenotypes and Gene Expression Heterogeneity at Single-cell Resolution in Cigarette-smoking Lungs
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    ncbi.nlm.nih.gov/pmc/articles/PMC10637260/
  90. Oct 2023
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MALAT1 Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10561629/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Analysis of Tumor Microenvironment Reveals Prognostic ceRNA Network Related to Immune Infiltration in Sarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10543973/
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prognostic Markers of DNA Methylation and Next-Generation Sequencing in Progressive Glioblastoma from the EORTC-26101 Trial
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    ncbi.nlm.nih.gov/pmc/articles/PMC10543963/
  94. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The role of differentiated dysplasia in the prediction of malignant transformation of oral leukoplakia
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    onlinelibrary.wiley.com/doi/10.1111/jop.13483
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-Scale Methylation Analysis Identifies Immune Profiles and Age Acceleration Associations with Bladder Cancer Outcomes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10543967/
  96. Sep 2023
  97. www.sciencedirect.com www.sciencedirect.com
    Single-cell profiling of murine bladder cancer identifies sex-specific transcriptional signatures with prognostic relevance
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    sciencedirect.com/science/article/pii/S2589004223017807
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic meta-analysis of levodopa induced dyskinesia in Parkinson’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10471743/
  99. Aug 2023
  100. bmcgastroenterol.biomedcentral.com bmcgastroenterol.biomedcentral.com
    Prognostic and biological function value of OSBPL3 in colorectal cancer analyzed by multi-omic data analysis
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    bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-023-02824-1
  101. dx.doi.org dx.doi.org
    Integrative single-cell and bulk transcriptomes analyses identify intrinsic HNSCC subtypes with distinct prognoses and therapeutic vulnerabilities
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    dx.doi.org/10.1158/1078-0432.CCR-22-3563
  102. Jul 2023
  103. link.springer.com link.springer.com
    Upregulation of FAM50A promotes cancer development
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    link.springer.com/article/10.1007/s12032-023-02072-z
  104. Jun 2023
  105. www.sciencedirect.com www.sciencedirect.com
    Microsatellite instability states serve as predictive biomarkers for tumors chemotherapy sensitivity
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    sciencedirect.com/science/article/pii/S2589004223011227
  106. May 2023
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Association of clinical outcomes and connectivity in awake versus asleep deep brain stimulation for Parkinson disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10215008/
  108. 52.53.155.43 52.53.155.43
    SAMHD1 Single Nucleotide Polymorphisms Impact Outcome in Children with Newly Diagnosed Acute Myeloid Leukemia
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  139. Sep 2021
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