76 Matching Annotations
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    Epigenetic and Transcriptional Programs Define Osteosarcoma Subtypes and Establish Targetable Vulnerabilities
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    pmc.ncbi.nlm.nih.gov/articles/PMC12877751/
  3. Jan 2026
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    Uncovering the signatures of aging and senescence in the human dorsolateral prefrontal cortex
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    sciencedirect.com/science/article/pii/S2666979X25003830
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    Biosafety assessment of engineered CCL20 locked dimers in vivo
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    Differential neuronal survival defines a novel axis of sexual dimorphism in the Drosophila brain
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    Protocol to evaluate mouse brain spatial cell type-resolved transcriptomic discoveries using 10× Visium spatial transcriptomics and FLEX scRNA-seq
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    sciencedirect.com/science/article/pii/S2666166725006835
  8. Dec 2025
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    A high-resolution atlas of the brain predicts lineage and birth order underlying neuronal identity
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    Mega-scale single-cell profiling reveals novel biomarkers associated with acute GvHD after allogeneic hematopoietic stem cell transplantation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12670839/
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    Digital twins for in vivo metabolic flux estimations in patients with brain cancer
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    C9orf72 Repeat Expansion Induces Metabolic Dysfunction in Human iPSC‐Derived Microglia and Modulates Glial‐Neuronal Crosstalk
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  13. Nov 2025
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    Circulating neoantigen- and viral oncoprotein–specific CD8+ T cells share a transcriptional signature
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    pmc.ncbi.nlm.nih.gov/articles/PMC12591038/
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    Trilaciclib triggers a neutrophil-related immune response and sensitizes non-small cell lung cancer to anti-PD-1 therapy
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  17. Oct 2025
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    Human heart-macrophage assembloids mimic immune-cardiac interactions and enable arrhythmia disease modeling
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    sciencedirect.com/science/article/pii/S1934590925003674
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    Fibroblast specialisation across microanatomy in a single-cell atlas of healthy human Achilles tendon
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    biorxiv.org/content/10.1101/2025.10.17.683019v1
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    Bone-Induced Her2 Promotes Secondary Metastasis in HR+/Her2− Breast Cancer
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  21. Sep 2025
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    Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4
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    A framework to mine laser microdissection-based omics data and uncover regulators of pancreatic cancer heterogeneity
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  24. Aug 2025
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    Endocardial primary cilia and blood flow regulate EndoMT during endocardial cushion development
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    AI-driven multimodal algorithm predicts immunotherapy and targeted therapy outcomes in clear cell renal cell carcinoma
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    HMGA2 Expression Predicts Subtype, Survival, and Treatment Outcome in Pancreatic Ductal Adenocarcinoma
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    Lipid nanoparticles as a tool to dissect dendritic cell maturation pathways
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    Characteristics of a CCL21 gene-modified dendritic cell vaccine utilized for a clinical trial in non-small cell lung cancer
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  30. Jul 2025
  31. www.biorxiv.org www.biorxiv.org
    A developmental program of early residency promotes the differentiation of divergent uterine NK cell subsets in humans
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    Insights into human melanocyte development and characteristics through pluripotent stem cells combined with single-cell sequencing
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  33. Jun 2025
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    Neurodevelopmental hijacking of oligodendrocyte lineage programs drives glioblastoma infiltration
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    cell.com/developmental-cell/abstract/S1534-5807(25)00260-6
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    Single-Cell Transcriptomic Landscape Deciphers Intratumoral Heterogeneity and Subtypes of Acral and Mucosal Melanomas
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  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial–Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune Microenvironment
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    Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics
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  38. May 2025
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    Multimodal analyses reveal genes driving electrophysiological maturation of neurons in the primate prefrontal cortex
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    Direct microglia replacement reveals pathologic and therapeutic contributions of brain macrophages to a monogenic neurological disease
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    Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target
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    Single-cell transcriptomic profiling reveals diversity in human iNKT cells across hematologic tissues
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  43. Apr 2025
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Determinants of Response to Sequential Pembrolizumab with Trastuzumab plus Platinum/5-FU in HER2-Positive Gastric Cancer: A Phase II Chemoimmunotherapy Trial
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    Lineage Tracing and Single-Cell RNA Sequencing Reveal a Common Transcriptional State in Breast Cancer Tumor–Initiating Cells Characterized by IFN/STAT1 Activity
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    Comparative single-cell transcriptomic profiling of patient-derived renal carcinoma cells in cellular and animal models of kidney cancer
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    Sex differences in DNMT3A-mutant clonal hematopoiesis and the effects of estrogen
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  48. Mar 2025
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    Human brain cell-type-specific aging clocks based on single-nuclei transcriptomics
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  50. Feb 2025
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    The endogenous antigen-specific CD8+ T cell repertoire is composed of unbiased and biased clonotypes with differential fate commitments
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    Methionine intervention induces PD-L1 expression to enhance the immune checkpoint therapy response in MTAP-deleted osteosarcoma
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    Copper Drives Remodeling of Metabolic State and Progression of Clear Cell Renal Cell Carcinoma
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    Myofibroblasts emerge during alveolar regeneration following influenza-virus-induced lung injury
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  55. Jan 2025
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    KDM6B-dependent epigenetic programming of uterine fibroblasts in early pregnancy regulates parturition timing in mice
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    Anatomical, subset, and HIV-dependent expression of viral sensors and restriction factors
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  58. Dec 2024
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    Early downmodulation of tumor glycolysis predicts response to fasting-mimicking diet in triple-negative breast cancer patients
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    Single-Cell Analysis of Bone Marrow CD8+ T Cells in Myeloid Neoplasms Reveals Pathways Associated with Disease Progression and Response to Treatment with Azacitidine
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    Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus
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    Combined inhibition of S100A4 and TIGIT suppresses late-stage breast cancer metastasis to the lung by activating T and NK cells
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  63. Nov 2024
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    Genetic requirement of dact1/2 to regulate noncanonical Wnt signaling and calpain 8 during embryonic convergent extension and craniofacial morphogenesis
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  66. Aug 2024
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    Mitochondrial serine catabolism safeguards maintenance of the hematopoietic stem cell pool in homeostasis and injury
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    Single-cell dissection of the human blood-brain barrier and glioma blood-tumor barrier
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    Experimental and Computational Methods for Allelic Imbalance Analysis from Single-Nucleus RNA-seq Data
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  70. Jul 2024
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    Timing of whole genome duplication is associated with tumor-specific MHC-II depletion in serous ovarian cancer
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    Synaptic plasticity in human thalamocortical assembloids
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  74. May 2024
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    PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma
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    Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma
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    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
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  78. Apr 2024
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    Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization
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    Single-cell transcriptomics reveals pre-existing COVID-19 vulnerability factors in lung cancer patients
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  81. Mar 2024
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    Deciphering the spatiotemporal transcriptional and chromatin accessibility of human retinal organoid development at the single-cell level
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    ncbi.nlm.nih.gov/pmc/articles/PMC10952046/
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    A TOPBP1 allele causing male infertility uncouples XY silencing dynamics from sex body formation
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  84. Dec 2023
  85. www.science.org www.science.org
    A single-cell multi-omic atlas spanning the adult rhesus macaque brain
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    science.org/doi/10.1126/sciadv.adh1914
  86. Nov 2023
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer-prone Phenotypes and Gene Expression Heterogeneity at Single-cell Resolution in Cigarette-smoking Lungs
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    ncbi.nlm.nih.gov/pmc/articles/PMC10637260/
  88. Oct 2023
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    A single-cell multi-omic atlas spanning the adult rhesus macaque brain
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  90. Aug 2023
  91. www.biorxiv.org www.biorxiv.org
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2
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    biorxiv.org/content/10.1101/2023.08.21.553157v1
  92. Jul 2023
  93. www.sciencedirect.com www.sciencedirect.com
    Cross-organ single-cell transcriptome profiling reveals macrophage and dendritic cell heterogeneity in zebrafish
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    Single-cell transcriptome atlas of Drosophila gastrula 2.0
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  95. Jun 2023
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    Organized B cell sites in cartilaginous fishes reveal the evolutionary foundation of germinal centers
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    hdWGCNA identifies co-expression networks in high-dimensional transcriptomics data
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  98. Apr 2023
  99. www.biorxiv.org www.biorxiv.org
    Brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke
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    biorxiv.org/content/10.1101/2023.03.31.535150v1
  100. Dec 2022
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell RNA sequencing uncovers dynamic roadmap and cell-cell communication during buffalo spermatogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9793287/
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    Nail-associated mesenchymal cells contribute to and are essential for dorsal digit tip regeneration
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    sciencedirect.com/science/article/pii/S2211124722017454
  103. aacrjournals.org aacrjournals.org
    BAF complex maintains glioma stem cells in pediatric H3K27M-glioma
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    aacrjournals.org/cancerdiscovery/article/12/12/2880/711164/BAF-Complex-Maintains-Glioma-Stem-Cells-in
  104. Jun 2022
  105. www.sciencedirect.com www.sciencedirect.com
    Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice
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