54 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    In vivo HSC gene therapy enables sustained eCD4-Ig expression for SIV prevention
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    sciencedirect.com/science/article/pii/S3117387X26000182
  3. www.sciencedirect.com www.sciencedirect.com
    In vivo production of an anti-HIV antibody in mice by non-viral gene knockin in primate hematopoietic stem and progenitor cells
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    sciencedirect.com/science/article/pii/S152500162600081X
  4. Feb 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comparative In Vitro Evaluation of Anti-HIV Immunotoxin, Antibody–Drug Conjugate, and Radioimmunoconjugate Targeted by the Same Antibody
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    pmc.ncbi.nlm.nih.gov/articles/PMC12921964/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engraftment of gene-edited hematopoietic stem cells after antibody-drug conjugate conditioning in nonhuman primates
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    pmc.ncbi.nlm.nih.gov/articles/PMC12915210/
  7. www.sciencedirect.com www.sciencedirect.com
    Transgenic mouse-derived human monoclonal antibodies targeting EBV gp350 and gp42 provide basis for therapeutic development
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    sciencedirect.com/science/article/pii/S2666379126000352
  8. Jan 2026
  9. www.sciencedirect.com www.sciencedirect.com
    In vitro evaluation of anti-HIV radioimmunoconjugates labeled with astatine-211, thorium-227 and actinium-225
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    sciencedirect.com/science/article/pii/S0969805126000016
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Monoclonal neutralizing antibodies elicited by infection with Kaposi sarcoma-associated herpesvirus reveal critical sites of vulnerability on gH/gL
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    pmc.ncbi.nlm.nih.gov/articles/PMC12795454/
  11. www.biorxiv.org www.biorxiv.org
    Influenza hemagglutinin subtypes have different sequence constraints despite sharing extremely similar structures
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    biorxiv.org/content/10.64898/2026.01.05.697808v1
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A CD8αβ co-receptor modified to contain an intracellular CD28 signaling tail enhances TCR-engineered T cell function independent of solid-tumor-associated co-stimulatory ligands
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    pmc.ncbi.nlm.nih.gov/articles/PMC12820041/
  13. Nov 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spike mutations that affect the function and antigenicity of recent KP.3.1.1-like SARS-CoV-2 variants
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    pmc.ncbi.nlm.nih.gov/articles/PMC12614646/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IL-2/IL-15 signaling induces NK cell production of FLT3LG augmenting anti-PD-1 immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12582536/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Heavy-chain immunoglobulin locus editing in rhesus macaque B cells to confer antibody production
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    pmc.ncbi.nlm.nih.gov/articles/PMC12554106/
  17. Oct 2025
  18. www.biorxiv.org www.biorxiv.org
    Functional and antigenic constraints on the Nipah virus fusion protein
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    biorxiv.org/content/10.1101/2025.10.15.682664v1
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Damage-induced IL-18 stimulates thymic NK cells limiting endogenous tissue regeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12479347/
  20. Sep 2025
  21. www.pnas.org www.pnas.org
    A TGF-βR/IL-2R immunomodulatory fusion protein transforms immunosuppression into T cell activation to enhance adoptive T cell therapy
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    pnas.org/doi/abs/10.1073/pnas.2516951122
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GroβT rapidly and reliably mobilizes primitive hematopoietic stem and progenitor cells in nonhuman primates
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    pmc.ncbi.nlm.nih.gov/articles/PMC12418998/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A discrete region of the D4Z4 is sufficient to initiate epigenetic silencing
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    pmc.ncbi.nlm.nih.gov/articles/PMC12409625/
  24. Aug 2025
  25. www.biorxiv.org www.biorxiv.org
    Spike mutations that affect the function and antigenicity of recent KP.3.1.1-like SARS-CoV-2 variants
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    biorxiv.org/content/10.1101/2025.08.18.671001v1
  26. www.science.org www.science.org
    Engraftment and persistence of HBB base-edited hematopoietic stem cells in nonhuman primates
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    science.org/doi/10.1126/scitranslmed.adn2601
  27. www.science.org www.science.org
    Breast milk IgG engages the mouse neonatal immune system to instruct responses to gut antigens
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    science.org/doi/10.1126/science.ado5294
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A rescue Fanconi anemia humanized mouse model with endogenous FA mutation and high human hematopoietic stem cell chimerism
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    pmc.ncbi.nlm.nih.gov/articles/PMC12355547/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Priming VRC01-precursor B cells with non-envelope immunogens disfavors boosting with HIV-1 envelope
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    pmc.ncbi.nlm.nih.gov/articles/PMC12325944/
  30. Jul 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RSV F evolution escapes some monoclonal antibodies but does not strongly erode neutralization by human polyclonal sera
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    pmc.ncbi.nlm.nih.gov/articles/PMC12282093/
  32. Jun 2025
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pleiotropic mutational effects on function and stability constrain the antigenic evolution of influenza hemagglutinin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12139742/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protection of CD33-modified hematopoietic stem cell progeny from CD33-directed CAR T cells in rhesus macaques
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    pmc.ncbi.nlm.nih.gov/articles/PMC12141896/
  35. May 2025
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    APOBEC3 Activity Promotes the Survival and Evolution of Drug-Tolerant Persister Cells during EGFR Inhibitor Resistance in Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12093302/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive maps of escape mutations from antibodies 10-1074 and 3BNC117 for Envs from two divergent HIV strains
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    pmc.ncbi.nlm.nih.gov/articles/PMC12090779/
  38. www.sciencedirect.com www.sciencedirect.com
    Deep mutational scanning of rabies glycoprotein defines mutational constraint and antibody-escape mutations
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    sciencedirect.com/science/article/pii/S1931312825001519
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Design of sensitive monospecific and bispecific synthetic chimeric T cell receptors for cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12037409/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD20 CAR T cells safely and reversibly ablate B cell follicles in a non-human primate model of HIV persistence
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    pmc.ncbi.nlm.nih.gov/articles/PMC11081808/
  41. Apr 2025
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RSV F evolution escapes some monoclonal antibodies but does not strongly erode neutralization by human polyclonal sera
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952455/
  43. Mar 2025
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Design of sensitive monospecific and bispecific synthetic chimeric T cell receptors for cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12037409/
  45. www.cell.com www.cell.com
    Functional and antigenic landscape of the Nipah virus receptor-binding protein
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    cell.com/cell/fulltext/S0092-8674(25)00257-0
  46. Feb 2025
  47. www.biorxiv.org www.biorxiv.org
    A discrete region of the D4Z4 is sufficient to initiate epigenetic silencing
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    biorxiv.org/content/10.1101/2025.02.19.639175v1
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive maps of escape mutations from antibodies 10-1074 and 3BNC117 for Envs from two divergent HIV strains
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    pmc.ncbi.nlm.nih.gov/articles/PMC11838258/
  49. Jan 2025
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deep mutational scanning of rabies glycoprotein defines mutational constraint and antibody-escape mutations
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    pmc.ncbi.nlm.nih.gov/articles/PMC11702696/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sir2 is required for the quiescence-specific condensed three-dimensional chromatin structure of rDNA
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    pmc.ncbi.nlm.nih.gov/articles/PMC11661206/
  52. Nov 2024
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional genomics screens reveal a role for TBC1D24 and SV2B in antibody-dependent enhancement of dengue virus infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC11578089/
  54. Jul 2024
  55. www.nature.com www.nature.com
    Spike deep mutational scanning helps predict success of SARS-CoV-2 clades
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    nature.com/articles/s41586-024-07636-1
  56. www.sciencedirect.com www.sciencedirect.com
    Deep mutational scanning reveals functional constraints and antibody-escape potential of Lassa virus glycoprotein complex
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    sciencedirect.com/science/article/pii/S1074761324003194
  57. May 2024
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sensitive bispecific chimeric T cell receptors for cancer therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11092799/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional and antigenic landscape of the Nipah virus receptor binding protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC11042328/
  60. Apr 2024
  61. onlinelibrary.wiley.com onlinelibrary.wiley.com
    OMIP-102: 50-color phenotyping of the human immune system with in-depth assessment of T cells and dendritic cells
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    onlinelibrary.wiley.com/doi/10.1002/cyto.a.24841
  62. Feb 2024
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deep mutational scanning reveals functional constraints and antigenic variability of Lassa virus glycoprotein complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC10871245/
  64. www.biorxiv.org www.biorxiv.org
    50-color phenotyping of the human immune system with in-depth assessment of T cells and dendritic cells
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    biorxiv.org/content/10.1101/2023.12.14.571745v1
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FLIP(C1orf112)-FIGNL1 complex regulates RAD51 chromatin association to promote viability after replication stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC10825145/
  66. Jan 2024
  67. www.biorxiv.org www.biorxiv.org
    50-color phenotyping of the human immune system with in-depth assessment of T cells and dendritic cells
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    biorxiv.org/content/10.1101/2023.12.14.571745v1
  68. Nov 2023
  69. www.biorxiv.org www.biorxiv.org
    Full-spike deep mutational scanning helps predict the evolutionary success of SARS-CoV-2 clades
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    biorxiv.org/content/10.1101/2023.11.13.566961v1
  70. Oct 2023
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses
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    ncbi.nlm.nih.gov/pmc/articles/PMC10586629/
  72. www.biorxiv.org www.biorxiv.org
    RADIF(C1orf112)-FIGNL1 Complex Regulates RAD51 Chromatin Association to Promote Viability After Replication Stress
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    biorxiv.org/content/10.1101/2023.09.25.556595v1
  73. Sep 2023
  74. journals.plos.org journals.plos.org
    The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs
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    journals.plos.org/plosbiology/article
  75. Jul 2023
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    APOBEC3 activity promotes the survival and evolution of drug-tolerant persister cells during acquired resistance to EGFR inhibitors in lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10350004/
  77. Jun 2023
  78. www.sciencedirect.com www.sciencedirect.com
    Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning
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    sciencedirect.com/science/article/pii/S1931312823002184
  79. Apr 2023
  80. www.biorxiv.org www.biorxiv.org
    Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning
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    biorxiv.org/content/10.1101/2023.03.23.533993v1