66 Matching Annotations
  1. Last 7 days
  2. www.biorxiv.org www.biorxiv.org
    Functional and acid-stability constraints on the Junin virus glycoprotein complex
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    biorxiv.org/content/10.64898/2026.10.22.761119v1
  3. Sep 2026
  4. journals.asm.org journals.asm.org
    Evaluating an anti-idiotype derived germline-targeting immunogen designed to elicit VRC01-class precursors in human antibody transgenic mice
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    journals.asm.org/doi/10.1128/msphere.00317-26
  5. www.science.org www.science.org
    Reprogramming engineered autologous T cells to overcome resistance in patients with Merkel cell carcinoma
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    science.org/doi/10.1126/scitranslmed.aea8773
  6. Aug 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pooled CAR-T screening in pig-tailed macaques identifies designs with enhanced proliferation, trafficking, and persistence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12809228/
  8. Jun 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KLF18 is a necessary component of the DUX4-initiated transcriptional network and a candidate locus for phenotypic diversity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13224869/
  10. Apr 2026
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Junction opener enables CAR T cell treatment of solid tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC13086946/
  12. insight.jci.org insight.jci.org
    An at-home blood collection device for remote immune monitoring by high-parameter flow cytometry
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    insight.jci.org/articles/view/201116
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deep mutational scanning reveals functional constraints and antibody-escape potential of Lassa virus glycoprotein complex
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    pmc.ncbi.nlm.nih.gov/articles/PMC11390330/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Influenza hemagglutinin subtypes have different sequence constraints despite sharing extremely similar structures
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    pmc.ncbi.nlm.nih.gov/articles/PMC13064934/
  15. Mar 2026
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pleiotropic mutational effects on function and stability constrain the antigenic evolution of influenza haemagglutinin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12758803/
  17. www.biorxiv.org www.biorxiv.org
    Mutations to the HCoV-229E spike have counterbalancing effects on serum antibody neutralization and receptor binding
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    biorxiv.org/content/10.64898/2026.02.22.707297v1
  18. www.biorxiv.org www.biorxiv.org
    CaptureBody – an anti-CD45 x anti-IgG bispecific antibody enables accurate unmixing for spectral flow cytometry
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    biorxiv.org/content/10.64898/2026.02.13.704926v1
  19. Feb 2026
  20. www.sciencedirect.com www.sciencedirect.com
    In vivo HSC gene therapy enables sustained eCD4-Ig expression for SIV prevention
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    sciencedirect.com/science/article/pii/S3117387X26000182
  21. www.sciencedirect.com www.sciencedirect.com
    In vivo production of an anti-HIV antibody in mice by non-viral gene knockin in primate hematopoietic stem and progenitor cells
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    sciencedirect.com/science/article/pii/S152500162600081X
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comparative In Vitro Evaluation of Anti-HIV Immunotoxin, Antibody–Drug Conjugate, and Radioimmunoconjugate Targeted by the Same Antibody
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    pmc.ncbi.nlm.nih.gov/articles/PMC12921964/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engraftment of gene-edited hematopoietic stem cells after antibody-drug conjugate conditioning in nonhuman primates
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    pmc.ncbi.nlm.nih.gov/articles/PMC12915210/
  24. www.sciencedirect.com www.sciencedirect.com
    Transgenic mouse-derived human monoclonal antibodies targeting EBV gp350 and gp42 provide basis for therapeutic development
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    sciencedirect.com/science/article/pii/S2666379126000352
  25. Jan 2026
  26. www.sciencedirect.com www.sciencedirect.com
    In vitro evaluation of anti-HIV radioimmunoconjugates labeled with astatine-211, thorium-227 and actinium-225
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    sciencedirect.com/science/article/pii/S0969805126000016
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Monoclonal neutralizing antibodies elicited by infection with Kaposi sarcoma-associated herpesvirus reveal critical sites of vulnerability on gH/gL
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    pmc.ncbi.nlm.nih.gov/articles/PMC12795454/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Influenza hemagglutinin subtypes have different sequence constraints despite sharing extremely similar structures
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    pmc.ncbi.nlm.nih.gov/articles/PMC12803193/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A CD8αβ co-receptor modified to contain an intracellular CD28 signaling tail enhances TCR-engineered T cell function independent of solid-tumor-associated co-stimulatory ligands
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    pmc.ncbi.nlm.nih.gov/articles/PMC12820041/
  30. Nov 2025
  31. journals.asm.org journals.asm.org
    Spike mutations that affect the function and antigenicity of recent KP.3.1.1-like SARS-CoV-2 variants | Journal of Virology
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    journals.asm.org/doi/10.1128/jvi.01423-25
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IL-2/IL-15 signaling induces NK cell production of FLT3LG augmenting anti-PD-1 immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12582536/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Heavy-chain immunoglobulin locus editing in rhesus macaque B cells to confer antibody production
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    pmc.ncbi.nlm.nih.gov/articles/PMC12554106/
  34. Oct 2025
  35. www.biorxiv.org www.biorxiv.org
    Functional and antigenic constraints on the Nipah virus fusion protein
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    biorxiv.org/content/10.1101/2025.10.15.682664v1
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Damage-induced IL-18 stimulates thymic NK cells limiting endogenous tissue regeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12479347/
  37. Sep 2025
  38. www.pnas.org www.pnas.org
    A TGF-βR/IL-2R immunomodulatory fusion protein transforms immunosuppression into T cell activation to enhance adoptive T cell therapy
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    pnas.org/doi/abs/10.1073/pnas.2516951122
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GroβT rapidly and reliably mobilizes primitive hematopoietic stem and progenitor cells in nonhuman primates
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    pmc.ncbi.nlm.nih.gov/articles/PMC12418998/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A discrete region of the D4Z4 is sufficient to initiate epigenetic silencing
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    pmc.ncbi.nlm.nih.gov/articles/PMC12409625/
  41. Aug 2025
  42. www.biorxiv.org www.biorxiv.org
    Spike mutations that affect the function and antigenicity of recent KP.3.1.1-like SARS-CoV-2 variants
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    biorxiv.org/content/10.1101/2025.08.18.671001v2
  43. www.science.org www.science.org
    Engraftment and persistence of HBB base-edited hematopoietic stem cells in nonhuman primates
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    science.org/doi/10.1126/scitranslmed.adn2601
  44. www.science.org www.science.org
    Breast milk IgG engages the mouse neonatal immune system to instruct responses to gut antigens
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    science.org/doi/10.1126/science.ado5294
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A rescue Fanconi anemia humanized mouse model with endogenous FA mutation and high human hematopoietic stem cell chimerism
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    pmc.ncbi.nlm.nih.gov/articles/PMC12355547/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Priming VRC01-precursor B cells with non-envelope immunogens disfavors boosting with HIV-1 envelope
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    pmc.ncbi.nlm.nih.gov/articles/PMC12325944/
  47. Jul 2025
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RSV F evolution escapes some monoclonal antibodies but does not strongly erode neutralization by human polyclonal sera
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    pmc.ncbi.nlm.nih.gov/articles/PMC12282093/
  49. Jun 2025
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pleiotropic mutational effects on function and stability constrain the antigenic evolution of influenza hemagglutinin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12139742/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protection of CD33-modified hematopoietic stem cell progeny from CD33-directed CAR T cells in rhesus macaques
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    pmc.ncbi.nlm.nih.gov/articles/PMC12141896/
  52. May 2025
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    APOBEC3 Activity Promotes the Survival and Evolution of Drug-Tolerant Persister Cells during EGFR Inhibitor Resistance in Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12093302/
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive maps of escape mutations from antibodies 10-1074 and 3BNC117 for Envs from two divergent HIV strains
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    pmc.ncbi.nlm.nih.gov/articles/PMC12090779/
  55. www.sciencedirect.com www.sciencedirect.com
    Deep mutational scanning of rabies glycoprotein defines mutational constraint and antibody-escape mutations
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    sciencedirect.com/science/article/pii/S1931312825001519
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Design of sensitive monospecific and bispecific synthetic chimeric T cell receptors for cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12037409/
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD20 CAR T cells safely and reversibly ablate B cell follicles in a non-human primate model of HIV persistence
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    pmc.ncbi.nlm.nih.gov/articles/PMC11081808/
  58. Apr 2025
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RSV F evolution escapes some monoclonal antibodies but does not strongly erode neutralization by human polyclonal sera
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952455/
  60. Mar 2025
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Design of sensitive monospecific and bispecific synthetic chimeric T cell receptors for cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12037409/
  62. www.cell.com www.cell.com
    Functional and antigenic landscape of the Nipah virus receptor-binding protein
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    cell.com/cell/fulltext/S0092-8674(25)00257-0
  63. Feb 2025
  64. www.biorxiv.org www.biorxiv.org
    A discrete region of the D4Z4 is sufficient to initiate epigenetic silencing
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    biorxiv.org/content/10.1101/2025.02.19.639175v1
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive maps of escape mutations from antibodies 10-1074 and 3BNC117 for Envs from two divergent HIV strains
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    pmc.ncbi.nlm.nih.gov/articles/PMC11838258/
  66. Jan 2025
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deep mutational scanning of rabies glycoprotein defines mutational constraint and antibody-escape mutations
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    pmc.ncbi.nlm.nih.gov/articles/PMC11702696/
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sir2 is required for the quiescence-specific condensed three-dimensional chromatin structure of rDNA
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    pmc.ncbi.nlm.nih.gov/articles/PMC11661206/
  69. Nov 2024
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional genomics screens reveal a role for TBC1D24 and SV2B in antibody-dependent enhancement of dengue virus infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC11578089/
  71. Jul 2024
  72. www.nature.com www.nature.com
    Spike deep mutational scanning helps predict success of SARS-CoV-2 clades
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    nature.com/articles/s41586-024-07636-1
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deep mutational scanning reveals functional constraints and antibody-escape potential of Lassa virus glycoprotein complex
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    pmc.ncbi.nlm.nih.gov/articles/PMC11390330/
  74. May 2024
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sensitive bispecific chimeric T cell receptors for cancer therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11092799/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional and antigenic landscape of the Nipah virus receptor binding protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC11042328/
  77. Apr 2024
  78. onlinelibrary.wiley.com onlinelibrary.wiley.com
    OMIP-102: 50-color phenotyping of the human immune system with in-depth assessment of T cells and dendritic cells
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    onlinelibrary.wiley.com/doi/10.1002/cyto.a.24841
  79. Feb 2024
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deep mutational scanning reveals functional constraints and antigenic variability of Lassa virus glycoprotein complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC10871245/
  81. www.biorxiv.org www.biorxiv.org
    50-color phenotyping of the human immune system with in-depth assessment of T cells and dendritic cells
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    biorxiv.org/content/10.1101/2023.12.14.571745v1
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FLIP(C1orf112)-FIGNL1 complex regulates RAD51 chromatin association to promote viability after replication stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC10825145/
  83. Jan 2024
  84. www.biorxiv.org www.biorxiv.org
    50-color phenotyping of the human immune system with in-depth assessment of T cells and dendritic cells
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    biorxiv.org/content/10.1101/2023.12.14.571745v1
  85. Nov 2023
  86. www.biorxiv.org www.biorxiv.org
    Full-spike deep mutational scanning helps predict the evolutionary success of SARS-CoV-2 clades
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    biorxiv.org/content/10.1101/2023.11.13.566961v1
  87. Oct 2023
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses
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    ncbi.nlm.nih.gov/pmc/articles/PMC10586629/
  89. www.biorxiv.org www.biorxiv.org
    RADIF(C1orf112)-FIGNL1 Complex Regulates RAD51 Chromatin Association to Promote Viability After Replication Stress
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    biorxiv.org/content/10.1101/2023.09.25.556595v1
  90. Sep 2023
  91. journals.plos.org journals.plos.org
    The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs
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    journals.plos.org/plosbiology/article
  92. Jul 2023
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    APOBEC3 activity promotes the survival and evolution of drug-tolerant persister cells during acquired resistance to EGFR inhibitors in lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10350004/
  94. Jun 2023
  95. www.sciencedirect.com www.sciencedirect.com
    Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning
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    sciencedirect.com/science/article/pii/S1931312823002184
  96. Apr 2023
  97. www.biorxiv.org www.biorxiv.org
    Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning
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    biorxiv.org/content/10.1101/2023.03.23.533993v1