55 Matching Annotations
  1. Last 7 days
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    HOPX regulates the development and lineage progression of human stem cell-derived outer radial glia-like cells
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    sciencedirect.com/science/article/pii/S2213671126002985
  3. Sep 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inflammatory bone marrow microenvironment impairs the therapeutic effect of daratumumab-lenalidomide in multiple myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13546506/
  5. Aug 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinct Transcriptional Programs Controlled by NR5A1 and β-Catenin in Adrenocortical Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13515156/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combined MYC Activation and PTEN Loss Drives Molecular Features of Aggressive Preinvasive Lesions in Mouse Prostate
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    pmc.ncbi.nlm.nih.gov/articles/PMC13482967/
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    Glycolytic enolase 1-induced H4K12 lactylation activates quiescent breast cancer stem-like cells in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13493833/
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    Viral mimicry redirects immunosuppressed colorectal tumour landscapes towards a proinflammatory and CMS1-like regenerative state
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    pmc.ncbi.nlm.nih.gov/articles/PMC13486658/
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    Targeting CCR1 remodels the tumor microenvironment and relieves immune suppression in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13429029/
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    Notch2 signaling instructs viral and bacterial TLR responsiveness in B cells
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    sciencedirect.com/science/article/pii/S2211124726008260
  12. Jul 2026
  13. aacrjournals.org aacrjournals.org
    In Silico Reconstruction of Primary and Metastatic Tumor Architecture using Geographic Information System-Augmented Spatial Transcriptomics
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    aacrjournals.org/cancerres/article/86/10/2555/784899/In-Silico-Reconstruction-of-Primary-and-Metastatic
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    Single-Cell and Spatial Transcriptomic Profiling Reveals Epithelial Functional States and Fibroblast Phenotypes in Hormone Therapy–Naïve Localized Prostate Cancer
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    aacrjournals.org/cancerres/article/86/8/1836/782625/Single-Cell-and-Spatial-Transcriptomic-Profiling
  15. Jun 2026
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    DPY30 is an epigenetic decoupler linking replication stress to immunoediting in pancreatic cancer
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    aacrjournals.org/cancerres/article/86/12/2837/785625/DPY30-Is-an-Epigenetic-Decoupler-Linking
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    Low-Strength Type I Interferon Signaling Promotes CAR T Cell Treatment Efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13249101/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CCL3+ neutrophil signature predicts response to neoadjuvant toripalimab plus chemotherapy in patients with hypopharyngeal squamous cell carcinoma: A phase II trial
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    pmc.ncbi.nlm.nih.gov/articles/PMC13223550/
  19. May 2026
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    A human iPSC-derived sensory neuron platform for high-throughput discovery of neuroprotectants against chemotherapy-induced peripheral neuropathy
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    sciencedirect.com/science/article/pii/S2666379126002041
  21. Apr 2026
  22. 54.241.53.176 54.241.53.176
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    P21-positive senescent stromal cells promote prostate cancer immune suppression and progression that can be reversed by senolytic therapy
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    aacrjournals.org/cancerdiscovery/article/16/3/571/774737/p21-Positive-Senescent-Stromal-Cells-Promote
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    Organ injury in systemic autoimmunity is mediated by stem-like CD8+ T cells arising from tissue-draining lymph nodes
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    Airway microbiome–host transcriptome networks link microbial dysbiosis to survival outcomes and therapeutic opportunities in severe COVID-19
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  26. Mar 2026
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    Myofibroblast programming blocks differentiation of TLS-organizing fibroblastic reticular cells in pancreatic cancer
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    Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy
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    sciencedirect.com/science/article/pii/S009286742600173X
  29. Feb 2026
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hypoxia Promotes an Adrenergic to Mesenchymal Transcriptional Program Transition in Neuroblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12928030/
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    Integrative Clinical and Molecular Evaluation of Renal Cell Carcinoma with Merlin Protein Deficiency and Biallelic Loss of NF2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12924687/
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    Metabolic reprogramming regulates histone lactylation during zebrafish caudal fin regeneration
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    Hormonal rewiring of immunity during dietary restriction ensures host defense and systemic glucose conservation
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    The molecular and functional landscape of resistance to FOLFIRI chemotherapy in metastatic colorectal cancer
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    Inhibition of focal adhesion kinase impairs tumor formation and preserves hearing in a murine model of NF2-related schwannomatosis
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    science.org/doi/10.1126/sciadv.ady8382
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    Inhibition of focal adhesion kinase impairs tumor formation and preserves hearing in a murine model of NF2-related schwannomatosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12857737/
  37. Dec 2025
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    SM08502-Mediated β-Catenin Repression Synergizes with Olaparib to Inhibit Tumor Progression
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  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Olaparib and radiotherapy induce type I interferon and CD8+ T cell-dependent sensitization to immunotherapy in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12137021/
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    Immunocompetent murine models recapitulate the heterogeneous tumor immune microenvironment of human liposarcoma
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  41. Nov 2025
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    Human fallopian tube epithelial organoids with TP53 mutation recapitulate features of serous tubal intraepithelial carcinoma (STIC)
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    sciencedirect.com/science/article/pii/S0090825825010765
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    Epigenetic profiling reveals key super-enhancer networks driving oncogenesis in HPV-positive HNSCC
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  44. Sep 2025
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Extracellular vesicle-associated transcriptomic and proteomic biomarkers show in vitro potential for vandetanib treatment monitoring in anaplastic thyroid cancer
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  46. Aug 2025
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    Phase 1/2 trial of encorafenib, cetuximab, and nivolumab in microsatellite stable BRAFV600E metastatic colorectal cancer
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  48. Jul 2025
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    Insights into human melanocyte development and characteristics through pluripotent stem cells combined with single-cell sequencing
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    pmc.ncbi.nlm.nih.gov/articles/PMC12245449/
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    Dissecting FAP+ Cell Diversity in Pancreatic Cancer Uncovers an Interferon-Response Subtype of Cancer-Associated Fibroblasts with Tumor-Restraining Properties
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    Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer
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    sciencedirect.com/science/article/pii/S1074761325002742
  52. Jun 2025
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-Cell Transcriptomic Landscape Deciphers Intratumoral Heterogeneity and Subtypes of Acral and Mucosal Melanomas
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    pmc.ncbi.nlm.nih.gov/articles/PMC12163602/
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  55. May 2025
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Heterogeneous Responses to High-Dose Testosterone in Castration-Resistant Prostate Cancer Tumors with Mixed Rb-Proficient and Rb-Deficient Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12046331/
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    Tumor break load quantitates structural variant-associated genomic instability with biological and clinical relevance across cancers
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    link.springer.com/article/10.1038/s41698-025-00922-9
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    High expression of THY1 is a prognostic marker for gastric Cancer: Deciphering its transcriptional regulation as a component of the Epithelial–mesenchymal transition
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    sciencedirect.com/science/article/pii/S2405580825001372
  59. Apr 2025
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clinical and Translational Results from PORTER, a Multicohort Phase I Platform Trial of Combination Immunotherapy in Metastatic Castration-Resistant Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11995007/
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    Comparative single-cell transcriptomic profiling of patient-derived renal carcinoma cells in cellular and animal models of kidney cancer
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70022
  62. Mar 2025
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    Antagonistic roles for MITF and TFE3 in melanoma plasticity
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    sciencedirect.com/science/article/pii/S2211124725002451
  64. Jan 2025
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    Cytoplasmic mRNA decay controlling inflammatory gene expression is determined by pre-mRNA fate decision
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    sciencedirect.com/science/article/pii/S1097276525000012
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  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RECQL4 affects MHC class II‐mediated signalling and favours an immune‐evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11734436/
  68. Dec 2024
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    Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer
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  70. Oct 2024
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    Oncogenic KRAS-dependent stromal interleukin-33 directs the pancreatic microenvironment to promote tumor growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC11450371/
  72. Apr 2024
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    Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization
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    sciencedirect.com/science/article/pii/S1535610824001193
  74. Oct 2023
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell transcriptome analysis illuminating the characteristics of species-specific innate immune responses against viral infections
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    ncbi.nlm.nih.gov/pmc/articles/PMC10580374/
  76. Jul 2023
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    Bacterial clade-specific analysis identifies distinct epithelial responses in inflammatory bowel disease
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    sciencedirect.com/science/article/pii/S2666379123002525
  78. May 2023
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    Modeling breast cancer proliferation, drug synergies, and alternating therapies
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    sciencedirect.com/science/article/pii/S2589004223007915