30 Matching Annotations
  1. Last 7 days
  2. dx.doi.org dx.doi.org
    The class A repeats of Lrp5 are required for normal development of bone, retinal vasculature, and mammary gland in vivo
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    dx.doi.org/10.1242/dmm.052280
  3. 54.241.53.176 54.241.53.176
    Bone marrow microenvironment signatures associate with patient survival after guadecitabine and atezolizumab therapy in HMA-resistant MDS
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    54.241.53.176/7ff534498f0f0e1bfd0b96ba61c0012f6b975734/1-s2.0-S2950328026000543-main-html.html
  4. Apr 2026
  5. www.biorxiv.org www.biorxiv.org
    Rise-and-fall dynamics reveal a molecular and cellular vulnerability axis in prion-like α-synuclein propagation
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    biorxiv.org/content/10.64898/2026.03.27.714785v1
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of ZNRF3/RNF43 unleashes EGFR in cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13068435/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Midbrain Tet1 dosage defines inter-individual binge-eating susceptibility
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    pmc.ncbi.nlm.nih.gov/articles/PMC13015413/
  8. www.biorxiv.org www.biorxiv.org
    Deletion of the Wnt regulator Znrf3 alters bone geometry without inducing high bone mass
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    biorxiv.org/content/10.64898/2026.03.30.715366v1
  9. Jan 2026
  10. www.biorxiv.org www.biorxiv.org
    System-wide profiling reveals metabolic alterations in a G2019S LRRK2 knockin mouse model of Parkinson’s disease: systemic depletion of pyrimidine nucleosides
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    biorxiv.org/content/10.64898/2025.12.31.697225v1
  11. Dec 2025
  12. www.nature.com www.nature.com
    Dnmt3a2 expression during embryonic development is required for phenotypic stability
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    nature.com/articles/s42003-025-09311-1
  13. Oct 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency
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    pmc.ncbi.nlm.nih.gov/articles/PMC12534512/
  15. Sep 2025
  16. www.biorxiv.org www.biorxiv.org
    EHMT2 Controls Neural Crest-Derived Craniofacial Development but is Dispensable in Limb Development
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    biorxiv.org/content/10.1101/2025.09.07.674526v1
  17. www.biorxiv.org www.biorxiv.org
    Lewy pathology accumulates in swollen corticostriatal synapses in α-synucleinopathies
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    biorxiv.org/content/10.1101/2025.08.27.672679v1
  18. Aug 2025
  19. www.sciencedirect.com www.sciencedirect.com
    Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T cell function and tumor control
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    sciencedirect.com/science/article/pii/S155041312500333X
  20. Jul 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dnmt3a2 expression during embryonic development is required for phenotypic stability
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12236915/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The prostacyclin receptor PTGIR is a NRF2-dependent regulator of CD8+ T cell exhaustion
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    pmc.ncbi.nlm.nih.gov/articles/PMC12208871/
  23. Jun 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pathological α-synuclein elicits granulovacuolar degeneration independent of tau
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    pmc.ncbi.nlm.nih.gov/articles/PMC12177994/
  25. Apr 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impact of BRCA mutations, age, surgical indication, and hormone status on the molecular phenotype of the human Fallopian tube
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    pmc.ncbi.nlm.nih.gov/articles/PMC11947093/
  27. Mar 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Expression of ENL YEATS domain tumor mutations in nephrogenic or stromal lineage impairs kidney development
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    pmc.ncbi.nlm.nih.gov/articles/PMC11909213/
  29. www.biorxiv.org www.biorxiv.org
    Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency
    1
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    biorxiv.org/content/10.1101/2025.03.07.642026v1
  30. Feb 2025
  31. www.biorxiv.org www.biorxiv.org
    Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability
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    biorxiv.org/content/10.1101/2024.10.22.619411v1
  32. Nov 2024
  33. 54.241.53.176 54.241.53.176
    Bone marrow microenvironment signatures associate with patient survival after guadecitabine and atezolizumab therapy in HMA-resistant MDS
    1
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    54.241.53.176/7ff534498f0f0e1bfd0b96ba61c0012f6b975734/1-s2.0-S2950328026000543-main-html.html
  34. Aug 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A potent and selective ENL degrader suppresses oncogenic gene expression and leukemia progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11352836/
  36. May 2024
  37. www.biorxiv.org www.biorxiv.org
    Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities
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    biorxiv.org/content/10.1101/2024.01.25.577280v1
  38. Mar 2024
  39. www.nature.com www.nature.com
    Spatial transcriptomics reveals molecular dysfunction associated with cortical Lewy pathology
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    nature.com/articles/s41467-024-47027-8
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10910783/
  41. Feb 2024
  42. www.biorxiv.org www.biorxiv.org
    Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer
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    biorxiv.org/content/10.1101/2024.01.10.574969v1
  43. Nov 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin-dependent High Bone Mass Induced by Loss of APC in Osteoblasts Does Not Require Lrp5 or Lrp6
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    ncbi.nlm.nih.gov/pmc/articles/PMC10613880/
  45. Oct 2023
  46. www.biorxiv.org www.biorxiv.org
    LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology spread
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    biorxiv.org/content/10.1101/2023.10.06.561190v1
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental priming of cancer susceptibility
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    ncbi.nlm.nih.gov/pmc/articles/PMC10515831/
  48. Aug 2023
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibiting WNT secretion reduces high bone mass caused by Sost loss-of-function or gain-of-function mutations in Lrp5
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    ncbi.nlm.nih.gov/pmc/articles/PMC10447437/
  50. May 2023
  51. www.biorxiv.org www.biorxiv.org
    Spatial transcriptomics reveals molecular dysfunction associated with Lewy pathology
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    biorxiv.org/content/10.1101/2023.05.17.541144v1